Found 54 hits Enz. Inhib. hit(s) with all data for entry = 50044130 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004514
(CHEMBL3233394)Show SMILES NS(=O)(=O)c1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C15H11N5O5S2/c16-26(22,23)11-3-1-2-9(6-11)13-8-20(19-17-13)10-4-5-12-14(7-10)27(24,25)18-15(12)21/h1-8H,(H,18,21)(H2,16,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004514
(CHEMBL3233394)Show SMILES NS(=O)(=O)c1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C15H11N5O5S2/c16-26(22,23)11-3-1-2-9(6-11)13-8-20(19-17-13)10-4-5-12-14(7-10)27(24,25)18-15(12)21/h1-8H,(H,18,21)(H2,16,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 7 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004512
(CHEMBL3233392)Show SMILES Cc1cc(ccc1F)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H11FN4O3S/c1-9-6-10(2-5-13(9)17)14-8-21(20-18-14)11-3-4-12-15(7-11)25(23,24)19-16(12)22/h2-8H,1H3,(H,19,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004515
(CHEMBL3233395)Show SMILES OC[C@H]1O[C@@H](OCc2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C16H18N4O9S/c21-5-10-12(22)13(23)14(24)16(29-10)28-6-7-4-20(19-17-7)8-1-2-9-11(3-8)30(26,27)18-15(9)25/h1-4,10,12-14,16,21-24H,5-6H2,(H,18,25)/t10-,12-,13+,14-,16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004509
(CHEMBL3233389)Show SMILES Cc1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O3S/c1-10-3-2-4-11(7-10)14-9-20(19-17-14)12-5-6-13-15(8-12)24(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004512
(CHEMBL3233392)Show SMILES Cc1cc(ccc1F)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H11FN4O3S/c1-9-6-10(2-5-13(9)17)14-8-21(20-18-14)11-3-4-12-15(7-11)25(23,24)19-16(12)22/h2-8H,1H3,(H,19,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004508
(CHEMBL3233388)Show SMILES O=C1NS(=O)(=O)c2cc(ccc12)-n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H10N4O3S/c20-15-12-7-6-11(8-14(12)23(21,22)17-15)19-9-13(16-18-19)10-4-2-1-3-5-10/h1-9H,(H,17,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004514
(CHEMBL3233394)Show SMILES NS(=O)(=O)c1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C15H11N5O5S2/c16-26(22,23)11-3-1-2-9(6-11)13-8-20(19-17-13)10-4-5-12-14(7-10)27(24,25)18-15(12)21/h1-8H,(H,18,21)(H2,16,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004509
(CHEMBL3233389)Show SMILES Cc1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O3S/c1-10-3-2-4-11(7-10)14-9-20(19-17-14)12-5-6-13-15(8-12)24(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004484
(CHEMBL3233386)Show InChI InChI=1S/C7H4N2O5S/c10-7-5-2-1-4(9(11)12)3-6(5)15(13,14)8-7/h1-3H,(H,8,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004513
(CHEMBL3233393)Show SMILES COc1ccc(-c2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)c(C)c1 Show InChI InChI=1S/C17H14N4O4S/c1-10-7-12(25-2)4-6-13(10)15-9-21(20-18-15)11-3-5-14-16(8-11)26(23,24)19-17(14)22/h3-9H,1-2H3,(H,19,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004513
(CHEMBL3233393)Show SMILES COc1ccc(-c2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)c(C)c1 Show InChI InChI=1S/C17H14N4O4S/c1-10-7-12(25-2)4-6-13(10)15-9-21(20-18-15)11-3-5-14-16(8-11)26(23,24)19-17(14)22/h3-9H,1-2H3,(H,19,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004511
(CHEMBL3233391)Show SMILES COc1ccc(cc1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O4S/c1-24-12-5-2-10(3-6-12)14-9-20(19-17-14)11-4-7-13-15(8-11)25(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 341 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004514
(CHEMBL3233394)Show SMILES NS(=O)(=O)c1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C15H11N5O5S2/c16-26(22,23)11-3-1-2-9(6-11)13-8-20(19-17-13)10-4-5-12-14(7-10)27(24,25)18-15(12)21/h1-8H,(H,18,21)(H2,16,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 354 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004510
(CHEMBL3233390)Show SMILES FC(F)(F)c1ccccc1-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H9F3N4O3S/c17-16(18,19)12-4-2-1-3-10(12)13-8-23(22-20-13)9-5-6-11-14(7-9)27(25,26)21-15(11)24/h1-8H,(H,21,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 443 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004507
(CHEMBL3233387)Show InChI InChI=1S/C7H4N4O3S/c8-11-9-4-1-2-5-6(3-4)15(13,14)10-7(5)12/h1-3H,(H,10,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 466 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004508
(CHEMBL3233388)Show SMILES O=C1NS(=O)(=O)c2cc(ccc12)-n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H10N4O3S/c20-15-12-7-6-11(8-14(12)23(21,22)17-15)19-9-13(16-18-19)10-4-2-1-3-5-10/h1-9H,(H,17,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 484 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004515
(CHEMBL3233395)Show SMILES OC[C@H]1O[C@@H](OCc2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C16H18N4O9S/c21-5-10-12(22)13(23)14(24)16(29-10)28-6-7-4-20(19-17-7)8-1-2-9-11(3-8)30(26,27)18-15(9)25/h1-4,10,12-14,16,21-24H,5-6H2,(H,18,25)/t10-,12-,13+,14-,16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 572 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50004506
(6-Aminosaccharin | CHEMBL2016952 | Saccharin deriv...)Show InChI InChI=1S/C7H6N2O3S/c8-4-1-2-5-6(3-4)13(11,12)9-7(5)10/h1-3H,8H2,(H,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 9 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 633 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004507
(CHEMBL3233387)Show InChI InChI=1S/C7H4N4O3S/c8-11-9-4-1-2-5-6(3-4)15(13,14)10-7(5)12/h1-3H,(H,10,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 665 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004510
(CHEMBL3233390)Show SMILES FC(F)(F)c1ccccc1-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H9F3N4O3S/c17-16(18,19)12-4-2-1-3-10(12)13-8-23(22-20-13)9-5-6-11-14(7-9)27(25,26)21-15(11)24/h1-8H,(H,21,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 747 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| 773 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 14 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004511
(CHEMBL3233391)Show SMILES COc1ccc(cc1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O4S/c1-24-12-5-2-10(3-6-12)14-9-20(19-17-14)11-4-7-13-15(8-11)25(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 866 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| 935 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 6 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004506
(6-Aminosaccharin | CHEMBL2016952 | Saccharin deriv...)Show InChI InChI=1S/C7H6N2O3S/c8-4-1-2-5-6(3-4)13(11,12)9-7(5)10/h1-3H,8H2,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| Article PubMed
| 2.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004512
(CHEMBL3233392)Show SMILES Cc1cc(ccc1F)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H11FN4O3S/c1-9-6-10(2-5-13(9)17)14-8-21(20-18-14)11-3-4-12-15(7-11)25(23,24)19-16(12)22/h2-8H,1H3,(H,19,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004507
(CHEMBL3233387)Show InChI InChI=1S/C7H4N4O3S/c8-11-9-4-1-2-5-6(3-4)15(13,14)10-7(5)12/h1-3H,(H,10,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004511
(CHEMBL3233391)Show SMILES COc1ccc(cc1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O4S/c1-24-12-5-2-10(3-6-12)14-9-20(19-17-14)11-4-7-13-15(8-11)25(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| MMDB PDB Article PubMed
| 5.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 7.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 5B expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| 7.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 4 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004510
(CHEMBL3233390)Show SMILES FC(F)(F)c1ccccc1-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H9F3N4O3S/c17-16(18,19)12-4-2-1-3-10(12)13-8-23(22-20-13)9-5-6-11-14(7-9)27(25,26)21-15(11)24/h1-8H,(H,21,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004507
(CHEMBL3233387)Show InChI InChI=1S/C7H4N4O3S/c8-11-9-4-1-2-5-6(3-4)15(13,14)10-7(5)12/h1-3H,(H,10,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004509
(CHEMBL3233389)Show SMILES Cc1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O3S/c1-10-3-2-4-11(7-10)14-9-20(19-17-14)12-5-6-13-15(8-12)24(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004513
(CHEMBL3233393)Show SMILES COc1ccc(-c2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)c(C)c1 Show InChI InChI=1S/C17H14N4O4S/c1-10-7-12(25-2)4-6-13(10)15-9-21(20-18-15)11-3-5-14-16(8-11)26(23,24)19-17(14)22/h3-9H,1-2H3,(H,19,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004508
(CHEMBL3233388)Show SMILES O=C1NS(=O)(=O)c2cc(ccc12)-n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H10N4O3S/c20-15-12-7-6-11(8-14(12)23(21,22)17-15)19-9-13(16-18-19)10-4-2-1-3-5-10/h1-9H,(H,17,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 5A expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50004484
(CHEMBL3233386)Show InChI InChI=1S/C7H4N2O5S/c10-7-5-2-1-4(9(11)12)3-6(5)15(13,14)8-7/h1-3H,(H,8,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 1.56E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 12 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM29278
(CHEMBL310671 | Garantose | SAC | Saccharimide | Sa...)Show InChI InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004506
(6-Aminosaccharin | CHEMBL2016952 | Saccharin deriv...)Show InChI InChI=1S/C7H6N2O3S/c8-4-1-2-5-6(3-4)13(11,12)9-7(5)10/h1-3H,8H2,(H,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004484
(CHEMBL3233386)Show InChI InChI=1S/C7H4N2O5S/c10-7-5-2-1-4(9(11)12)3-6(5)15(13,14)8-7/h1-3H,(H,8,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004508
(CHEMBL3233388)Show SMILES O=C1NS(=O)(=O)c2cc(ccc12)-n1cc(nn1)-c1ccccc1 Show InChI InChI=1S/C15H10N4O3S/c20-15-12-7-6-11(8-14(12)23(21,22)17-15)19-9-13(16-18-19)10-4-2-1-3-5-10/h1-9H,(H,17,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004509
(CHEMBL3233389)Show SMILES Cc1cccc(c1)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H12N4O3S/c1-10-3-2-4-11(7-10)14-9-20(19-17-14)12-5-6-13-15(8-12)24(22,23)18-16(13)21/h2-9H,1H3,(H,18,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004512
(CHEMBL3233392)Show SMILES Cc1cc(ccc1F)-c1cn(nn1)-c1ccc2C(=O)NS(=O)(=O)c2c1 Show InChI InChI=1S/C16H11FN4O3S/c1-9-6-10(2-5-13(9)17)14-8-21(20-18-14)11-3-4-12-15(7-11)25(23,24)19-16(12)22/h2-8H,1H3,(H,19,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50004515
(CHEMBL3233395)Show SMILES OC[C@H]1O[C@@H](OCc2cn(nn2)-c2ccc3C(=O)NS(=O)(=O)c3c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C16H18N4O9S/c21-5-10-12(22)13(23)14(24)16(29-10)28-6-7-4-20(19-17-7)8-1-2-9-11(3-8)30(26,27)18-15(9)25/h1-4,10,12-14,16,21-24H,5-6H2,(H,18,25)/t10-,12-,13+,14-,16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 1 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004484
(CHEMBL3233386)Show InChI InChI=1S/C7H4N2O5S/c10-7-5-2-1-4(9(11)12)3-6(5)15(13,14)8-7/h1-3H,(H,8,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50004506
(6-Aminosaccharin | CHEMBL2016952 | Saccharin deriv...)Show InChI InChI=1S/C7H6N2O3S/c8-4-1-2-5-6(3-4)13(11,12)9-7(5)10/h1-3H,8H2,(H,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carbonic anhydrase 2 expressed in Escherichia coli by stopped flow CO2 hydration assay |
J Med Chem 57: 3522-31 (2014)
Article DOI: 10.1021/jm500255y BindingDB Entry DOI: 10.7270/Q2NS0WF1 |
More data for this Ligand-Target Pair | |