Found 43 hits Enz. Inhib. hit(s) with all data for entry = 50011273 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104486
(CHEMBL432562 | [(S)-1-[(S)-1-{12-[(2-Chloro-phenox...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H59ClN5O8P/c1-45(2,3)58-44(54)51-40(30-34-28-32-20-12-15-23-37(32)49-34)43(53)50-39(29-33-31-48-38-24-16-13-21-35(33)38)42(52)47-26-18-10-8-6-4-5-7-9-11-19-27-57-60(55,56)59-41-25-17-14-22-36(41)46/h12-17,20-25,28,31,39-40,48-49H,4-11,18-19,26-27,29-30H2,1-3H3,(H,47,52)(H,50,53)(H,51,54)(H,55,56)/t39-,40-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104475
(CHEMBL83388 | Phosphoric acid 2-chloro-phenyl este...)Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCCCCCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C40H51ClN3O5P/c1-32-30-43(37-22-13-10-19-34(32)37)26-18-27-44-31-33(35-20-11-14-23-38(35)44)29-40(45)42-25-16-8-6-4-2-3-5-7-9-17-28-48-50(46,47)49-39-24-15-12-21-36(39)41/h10-15,19-24,30-31H,2-9,16-18,25-29H2,1H3,(H,42,45)(H,46,47) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104490
(CHEMBL314864 | [(R)-1-{12-[(2-Chloro-phenoxy)-hydr...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)Oc1ccccc1Cl Show InChI InChI=1S/C37H47ClN3O7P/c38-32-21-13-15-23-35(32)48-49(44,45)47-25-17-8-6-4-2-1-3-5-7-16-24-39-36(42)34(26-30-27-40-33-22-14-12-20-31(30)33)41-37(43)46-28-29-18-10-9-11-19-29/h9-15,18-23,27,34,40H,1-8,16-17,24-26,28H2,(H,39,42)(H,41,43)(H,44,45)/t34-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104495
((R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-ch...)Show SMILES CC(C)(C)OC(=O)N[C@H](CCC(=O)OCc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C46H62ClN4O10P/c1-46(2,3)60-45(55)51-39(27-28-42(52)58-33-34-21-13-12-14-22-34)44(54)50-40(31-35-32-49-38-25-17-15-23-36(35)38)43(53)48-29-19-10-8-6-4-5-7-9-11-20-30-59-62(56,57)61-41-26-18-16-24-37(41)47/h12-18,21-26,32,39-40,49H,4-11,19-20,27-31,33H2,1-3H3,(H,48,53)(H,50,54)(H,51,55)(H,56,57)/t39-,40-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104466
(CHEMBL314040 | {(R)-1-[(R)-1-{12-[(2-Chloro-phenox...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C43H58ClN4O8P/c1-43(2,3)55-42(51)48-37(29-32-21-13-12-14-22-32)41(50)47-38(30-33-31-46-36-25-17-15-23-34(33)36)40(49)45-27-19-10-8-6-4-5-7-9-11-20-28-54-57(52,53)56-39-26-18-16-24-35(39)44/h12-18,21-26,31,37-38,46H,4-11,19-20,27-30H2,1-3H3,(H,45,49)(H,47,50)(H,48,51)(H,52,53)/t37-,38-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104484
(CHEMBL314057 | Phosphoric acid 12-[(R)-2-benzoylam...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1)Oc1ccccc1Cl Show InChI InChI=1S/C36H45ClN3O6P/c37-31-21-13-15-23-34(31)46-47(43,44)45-25-17-8-6-4-2-1-3-5-7-16-24-38-36(42)33(40-35(41)28-18-10-9-11-19-28)26-29-27-39-32-22-14-12-20-30(29)32/h9-15,18-23,27,33,39H,1-8,16-17,24-26H2,(H,38,42)(H,40,41)(H,43,44)/t33-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104473
((R)-2-[(R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosp...)Show SMILES CC(C)(C)OC(=O)N1CCC[C@@H]1C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C39H56ClN4O8P/c1-39(2,3)51-38(47)44-25-18-22-34(44)37(46)43-33(27-29-28-42-32-21-14-12-19-30(29)32)36(45)41-24-16-10-8-6-4-5-7-9-11-17-26-50-53(48,49)52-35-23-15-13-20-31(35)40/h12-15,19-21,23,28,33-34,42H,4-11,16-18,22,24-27H2,1-3H3,(H,41,45)(H,43,46)(H,48,49)/t33-,34-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104489
(CHEMBL313020 | Phosphoric acid 12-[(S)-2-[(R)-2-am...)Show SMILES N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H51ClN5O6P/c41-33-19-11-14-22-38(33)52-53(49,50)51-24-16-8-6-4-2-1-3-5-7-15-23-43-40(48)37(26-30-28-44-36-21-13-10-18-32(30)36)46-39(47)34(42)27-31-25-29-17-9-12-20-35(29)45-31/h9-14,17-22,25,28,34,37,44-45H,1-8,15-16,23-24,26-27,42H2,(H,43,48)(H,46,47)(H,49,50)/t34-,37+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104464
(CHEMBL405650 | Phosphoric acid 12-[(S)-2-[(S)-2-am...)Show SMILES N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H51ClN5O6P/c41-33-19-11-14-22-38(33)52-53(49,50)51-24-16-8-6-4-2-1-3-5-7-15-23-43-40(48)37(26-30-28-44-36-21-13-10-18-32(30)36)46-39(47)34(42)27-31-25-29-17-9-12-20-35(29)45-31/h9-14,17-22,25,28,34,37,44-45H,1-8,15-16,23-24,26-27,42H2,(H,43,48)(H,46,47)(H,49,50)/t34-,37-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104467
(CHEMBL437042 | {[(R)-1-{12-[(2-Chloro-phenoxy)-hyd...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)OCc1ccccc1)Oc1ccccc1Cl Show InChI InChI=1S/C39H50ClN4O8P/c40-33-21-13-15-23-36(33)52-53(48,49)51-25-17-8-6-4-2-1-3-5-7-16-24-41-38(46)35(26-31-27-42-34-22-14-12-20-32(31)34)44-37(45)28-43-39(47)50-29-30-18-10-9-11-19-30/h9-15,18-23,27,35,42H,1-8,16-17,24-26,28-29H2,(H,41,46)(H,43,47)(H,44,45)(H,48,49)/t35-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104471
(CHEMBL87995 | Phosphoric acid 12-[(R)-2-[(R)-2-ami...)Show SMILES N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H51ClN5O6P/c41-33-19-11-14-22-38(33)52-53(49,50)51-24-16-8-6-4-2-1-3-5-7-15-23-43-40(48)37(26-30-28-44-36-21-13-10-18-32(30)36)46-39(47)34(42)27-31-25-29-17-9-12-20-35(29)45-31/h9-14,17-22,25,28,34,37,44-45H,1-8,15-16,23-24,26-27,42H2,(H,43,48)(H,46,47)(H,49,50)/t34-,37-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104469
(CHEMBL85749 | Phosphoric acid 12-[(S)-2-amino-3-(1...)Show SMILES N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C29H41ClN3O5P/c30-25-16-10-12-18-28(25)38-39(35,36)37-20-14-8-6-4-2-1-3-5-7-13-19-32-29(34)26(31)21-23-22-33-27-17-11-9-15-24(23)27/h9-12,15-18,22,26,33H,1-8,13-14,19-21,31H2,(H,32,34)(H,35,36)/t26-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104457
(CHEMBL85239 | [(R)-1-{12-[(2-Chloro-phenoxy)-hydro...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C34H49ClN3O7P/c1-34(2,3)44-33(40)38-30(24-26-25-37-29-20-14-12-18-27(26)29)32(39)36-22-16-10-8-6-4-5-7-9-11-17-23-43-46(41,42)45-31-21-15-13-19-28(31)35/h12-15,18-21,25,30,37H,4-11,16-17,22-24H2,1-3H3,(H,36,39)(H,38,40)(H,41,42)/t30-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104470
(CHEMBL431613 | [(R)-1-[(R)-1-{12-[(2-Chloro-phenox...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H59ClN5O8P/c1-45(2,3)58-44(54)51-40(30-34-28-32-20-12-15-23-37(32)49-34)43(53)50-39(29-33-31-48-38-24-16-13-21-35(33)38)42(52)47-26-18-10-8-6-4-5-7-9-11-19-27-57-60(55,56)59-41-25-17-14-22-36(41)46/h12-17,20-25,28,31,39-40,48-49H,4-11,18-19,26-27,29-30H2,1-3H3,(H,47,52)(H,50,53)(H,51,54)(H,55,56)/t39-,40-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104465
(CHEMBL85748 | [(S)-1-{12-[(2-Chloro-phenoxy)-hydro...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C34H49ClN3O7P/c1-34(2,3)44-33(40)38-30(24-26-25-37-29-20-14-12-18-27(26)29)32(39)36-22-16-10-8-6-4-5-7-9-11-17-23-43-46(41,42)45-31-21-15-13-19-28(31)35/h12-15,18-21,25,30,37H,4-11,16-17,22-24H2,1-3H3,(H,36,39)(H,38,40)(H,41,42)/t30-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104478
(CHEMBL409072 | Phosphoric acid 12-[(R)-2-((R)-2-am...)Show SMILES N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C38H50ClN4O6P/c39-32-21-13-15-23-36(32)49-50(46,47)48-25-17-8-6-4-2-1-3-5-7-16-24-41-38(45)35(27-30-28-42-34-22-14-12-20-31(30)34)43-37(44)33(40)26-29-18-10-9-11-19-29/h9-15,18-23,28,33,35,42H,1-8,16-17,24-27,40H2,(H,41,45)(H,43,44)(H,46,47)/t33-,35-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104497
(CHEMBL87116 | Phosphoric acid 12-[(R)-2-[(R)-2-ace...)Show SMILES CC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C42H53ClN5O7P/c1-30(49)46-39(28-33-26-31-18-10-13-21-36(31)47-33)42(51)48-38(27-32-29-45-37-22-14-11-19-34(32)37)41(50)44-24-16-8-6-4-2-3-5-7-9-17-25-54-56(52,53)55-40-23-15-12-20-35(40)43/h10-15,18-23,26,29,38-39,45,47H,2-9,16-17,24-25,27-28H2,1H3,(H,44,50)(H,46,49)(H,48,51)(H,52,53)/t38-,39-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104483
(CHEMBL313009 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C34H39ClN3O5P/c1-26-24-37(31-16-7-4-13-28(26)31)20-12-21-38-25-27(29-14-5-8-17-32(29)38)23-34(39)36-19-10-2-3-11-22-42-44(40,41)43-33-18-9-6-15-30(33)35/h4-9,13-18,24-25H,2-3,10-12,19-23H2,1H3,(H,36,39)(H,40,41) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104499
(CHEMBL313818 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)CCCc1c[nH]c2ccccc12)Oc1ccccc1Cl Show InChI InChI=1S/C30H42ClN2O5P/c31-27-18-10-12-20-29(27)38-39(35,36)37-23-14-8-6-4-2-1-3-5-7-13-22-32-30(34)21-15-16-25-24-33-28-19-11-9-17-26(25)28/h9-12,17-20,24,33H,1-8,13-16,21-23H2,(H,32,34)(H,35,36) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104485
(CHEMBL86349 | Phosphoric acid 2-chloro-phenyl este...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)Cc1c[nH]c2ccccc12)Oc1ccccc1Cl Show InChI InChI=1S/C28H38ClN2O5P/c29-25-16-10-12-18-27(25)36-37(33,34)35-20-14-8-6-4-2-1-3-5-7-13-19-30-28(32)21-23-22-31-26-17-11-9-15-24(23)26/h9-12,15-18,22,31H,1-8,13-14,19-21H2,(H,30,32)(H,33,34) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104474
(CHEMBL262163 | Phosphoric acid 12-[(R)-2-amino-3-(...)Show SMILES N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C29H41ClN3O5P/c30-25-16-10-12-18-28(25)38-39(35,36)37-20-14-8-6-4-2-1-3-5-7-13-19-32-29(34)26(31)21-23-22-33-27-17-11-9-15-24(23)27/h9-12,15-18,22,26,33H,1-8,13-14,19-21,31H2,(H,32,34)(H,35,36)/t26-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104480
(CHEMBL420795 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCC(=O)N3CCCC3C(=O)NCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C43H53ClN5O7P/c1-32-30-47(37-18-7-4-15-34(32)37)25-14-26-48-31-33(35-16-5-8-19-38(35)48)29-41(50)45-24-12-22-42(51)49-27-13-20-39(49)43(52)46-23-10-2-3-11-28-55-57(53,54)56-40-21-9-6-17-36(40)44/h4-9,15-19,21,30-31,39H,2-3,10-14,20,22-29H2,1H3,(H,45,50)(H,46,52)(H,53,54) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104458
(CHEMBL84794 | Phosphoric acid 12-[(R)-2-acetylamin...)Show SMILES CC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C31H43ClN3O6P/c1-24(36)35-29(22-25-23-34-28-18-12-10-16-26(25)28)31(37)33-20-14-8-6-4-2-3-5-7-9-15-21-40-42(38,39)41-30-19-13-11-17-27(30)32/h10-13,16-19,23,29,34H,2-9,14-15,20-22H2,1H3,(H,33,37)(H,35,36)(H,38,39)/t29-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 9.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104477
(CHEMBL274683 | [(R)-1-[(R)-1-{3-[({6-[(2-Chloro-ph...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H57ClN7O10P/c1-45(2,3)62-44(58)53-38(27-32-25-30-15-6-9-18-35(30)51-32)43(57)52-37(26-31-28-49-36-19-10-7-16-33(31)36)42(56)48-23-14-21-40(54)50-29-41(55)47-22-12-4-5-13-24-61-64(59,60)63-39-20-11-8-17-34(39)46/h6-11,15-20,25,28,37-38,49,51H,4-5,12-14,21-24,26-27,29H2,1-3H3,(H,47,55)(H,48,56)(H,50,54)(H,52,57)(H,53,58)(H,59,60)/t37-,38-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104481
(CHEMBL315683 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C40H49ClN5O7P/c1-30-28-45(35-17-7-4-14-32(30)35)23-13-24-46-29-31(33-15-5-8-18-36(33)46)26-39(48)42-22-12-20-38(47)44-27-40(49)43-21-10-2-3-11-25-52-54(50,51)53-37-19-9-6-16-34(37)41/h4-9,14-19,28-29H,2-3,10-13,20-27H2,1H3,(H,42,48)(H,43,49)(H,44,47)(H,50,51) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104482
(CHEMBL316111 | Phosphoric acid 6-(2-{4-[(S)-2-[(R)...)Show SMILES N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H49ClN7O8P/c41-31-14-5-8-17-36(31)56-57(53,54)55-21-10-2-1-9-19-43-38(50)26-46-37(49)18-11-20-44-40(52)35(23-28-25-45-34-16-7-4-13-30(28)34)48-39(51)32(42)24-29-22-27-12-3-6-15-33(27)47-29/h3-8,12-17,22,25,32,35,45,47H,1-2,9-11,18-21,23-24,26,42H2,(H,43,50)(H,44,52)(H,46,49)(H,48,51)(H,53,54)/t32-,35+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104476
(CHEMBL315431 | Phosphoric acid 12-[(R)-2-((S)-2-am...)Show SMILES N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C38H50ClN4O6P/c39-32-21-13-15-23-36(32)49-50(46,47)48-25-17-8-6-4-2-1-3-5-7-16-24-41-38(45)35(27-30-28-42-34-22-14-12-20-31(30)34)43-37(44)33(40)26-29-18-10-9-11-19-29/h9-15,18-23,28,33,35,42H,1-8,16-17,24-27,40H2,(H,41,45)(H,43,44)(H,46,47)/t33-,35+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104472
(CHEMBL314161 | {(S)-1-[(R)-1-{12-[(2-Chloro-phenox...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C43H58ClN4O8P/c1-43(2,3)55-42(51)48-37(29-32-21-13-12-14-22-32)41(50)47-38(30-33-31-46-36-25-17-15-23-34(33)36)40(49)45-27-19-10-8-6-4-5-7-9-11-20-28-54-57(52,53)56-39-26-18-16-24-35(39)44/h12-18,21-26,31,37-38,46H,4-11,19-20,27-30H2,1-3H3,(H,45,49)(H,47,50)(H,48,51)(H,52,53)/t37-,38+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104468
(CHEMBL313345 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1)Oc1ccccc1Cl Show InChI InChI=1S/C34H48ClN4O6P/c35-28-17-10-12-20-32(28)45-46(42,43)44-23-14-8-6-4-2-1-3-5-7-13-21-37-33(40)31(39-34(41)30-19-15-22-36-30)24-26-25-38-29-18-11-9-16-27(26)29/h9-12,16-18,20,25,30-31,36,38H,1-8,13-15,19,21-24H2,(H,37,40)(H,39,41)(H,42,43)/t30-,31-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104463
(((R)-1-{12-[(2-Chloro-phenoxy)-hydroxy-phosphorylo...)Show SMILES OP(=O)(OCCCCCCCCCCCCNC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1)Oc1ccccc1Cl Show InChI InChI=1S/C35H46ClN2O7P/c36-31-23-15-16-24-33(31)45-46(41,42)44-26-18-8-6-4-2-1-3-5-7-17-25-37-34(39)32(27-29-19-11-9-12-20-29)38-35(40)43-28-30-21-13-10-14-22-30/h9-16,19-24,32H,1-8,17-18,25-28H2,(H,37,39)(H,38,40)(H,41,42)/t32-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104488
(CHEMBL384288 | [(S)-1-[(S)-1-{3-[({6-[(2-Chloro-ph...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H57ClN7O10P/c1-45(2,3)62-44(58)53-38(27-32-25-30-15-6-9-18-35(30)51-32)43(57)52-37(26-31-28-49-36-19-10-7-16-33(31)36)42(56)48-23-14-21-40(54)50-29-41(55)47-22-12-4-5-13-24-61-64(59,60)63-39-20-11-8-17-34(39)46/h6-11,15-20,25,28,37-38,49,51H,4-5,12-14,21-24,26-27,29H2,1-3H3,(H,47,55)(H,48,56)(H,50,54)(H,52,57)(H,53,58)(H,59,60)/t37-,38-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104462
(CHEMBL85434 | [(S)-1-[(R)-1-{12-[(2-Chloro-phenoxy...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H59ClN5O8P/c1-45(2,3)58-44(54)51-40(30-34-28-32-20-12-15-23-37(32)49-34)43(53)50-39(29-33-31-48-38-24-16-13-21-35(33)38)42(52)47-26-18-10-8-6-4-5-7-9-11-19-27-57-60(55,56)59-41-25-17-14-22-36(41)46/h12-17,20-25,28,31,39-40,48-49H,4-11,18-19,26-27,29-30H2,1-3H3,(H,47,52)(H,50,53)(H,51,54)(H,55,56)/t39-,40+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104487
(CHEMBL430453 | Phosphoric acid 2-chloro-phenyl est...)Show SMILES Cc1cn(CCCn2cc(CC(=O)NCCOCCOCCOCCOP(O)(=O)Oc3ccccc3Cl)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C36H43ClN3O8P/c1-28-26-39(33-12-5-2-9-30(28)33)16-8-17-40-27-29(31-10-3-6-13-34(31)40)25-36(41)38-15-18-44-19-20-45-21-22-46-23-24-47-49(42,43)48-35-14-7-4-11-32(35)37/h2-7,9-14,26-27H,8,15-25H2,1H3,(H,38,41)(H,42,43) | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104493
((R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-ch...)Show SMILES CC(C)(C)OC(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C39H56ClN4O10P/c1-39(2,3)53-38(49)44-32(22-23-35(45)46)37(48)43-33(26-28-27-42-31-20-14-12-18-29(28)31)36(47)41-24-16-10-8-6-4-5-7-9-11-17-25-52-55(50,51)54-34-21-15-13-19-30(34)40/h12-15,18-21,27,32-33,42H,4-11,16-17,22-26H2,1-3H3,(H,41,47)(H,43,48)(H,44,49)(H,45,46)(H,50,51)/t32-,33-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104492
(CHEMBL407131 | [(S)-1-[(R)-1-{3-[({6-[(2-Chloro-ph...)Show SMILES CC(C)(C)OC(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H57ClN7O10P/c1-45(2,3)62-44(58)53-38(27-32-25-30-15-6-9-18-35(30)51-32)43(57)52-37(26-31-28-49-36-19-10-7-16-33(31)36)42(56)48-23-14-21-40(54)50-29-41(55)47-22-12-4-5-13-24-61-64(59,60)63-39-20-11-8-17-34(39)46/h6-11,15-20,25,28,37-38,49,51H,4-5,12-14,21-24,26-27,29H2,1-3H3,(H,47,55)(H,48,56)(H,50,54)(H,52,57)(H,53,58)(H,59,60)/t37-,38+/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104491
(CHEMBL83234 | Phosphoric acid 6-(2-{4-[(S)-2-[(S)-...)Show SMILES N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H49ClN7O8P/c41-31-14-5-8-17-36(31)56-57(53,54)55-21-10-2-1-9-19-43-38(50)26-46-37(49)18-11-20-44-40(52)35(23-28-25-45-34-16-7-4-13-30(28)34)48-39(51)32(42)24-29-22-27-12-3-6-15-33(27)47-29/h3-8,12-17,22,25,32,35,45,47H,1-2,9-11,18-21,23-24,26,42H2,(H,43,50)(H,44,52)(H,46,49)(H,48,51)(H,53,54)/t32-,35-/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104461
(CHEMBL313922 | Phosphoric acid 6-[(R)-2-amino-3-(1...)Show SMILES N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C23H29ClN3O5P/c24-19-10-4-6-12-22(19)32-33(29,30)31-14-8-2-1-7-13-26-23(28)20(25)15-17-16-27-21-11-5-3-9-18(17)21/h3-6,9-12,16,20,27H,1-2,7-8,13-15,25H2,(H,26,28)(H,29,30)/t20-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104494
(CHEMBL87554 | Phosphoric acid 6-(2-{4-[(R)-2-[(R)-...)Show SMILES N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H49ClN7O8P/c41-31-14-5-8-17-36(31)56-57(53,54)55-21-10-2-1-9-19-43-38(50)26-46-37(49)18-11-20-44-40(52)35(23-28-25-45-34-16-7-4-13-30(28)34)48-39(51)32(42)24-29-22-27-12-3-6-15-33(27)47-29/h3-8,12-17,22,25,32,35,45,47H,1-2,9-11,18-21,23-24,26,42H2,(H,43,50)(H,44,52)(H,46,49)(H,48,51)(H,53,54)/t32-,35-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104460
(CHEMBL86385 | Phosphoric acid 6-(2-{4-[(R)-2-[(S)-...)Show SMILES N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C40H49ClN7O8P/c41-31-14-5-8-17-36(31)56-57(53,54)55-21-10-2-1-9-19-43-38(50)26-46-37(49)18-11-20-44-40(52)35(23-28-25-45-34-16-7-4-13-30(28)34)48-39(51)32(42)24-29-22-27-12-3-6-15-33(27)47-29/h3-8,12-17,22,25,32,35,45,47H,1-2,9-11,18-21,23-24,26,42H2,(H,43,50)(H,44,52)(H,46,49)(H,48,51)(H,53,54)/t32-,35+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104459
(CHEMBL314847 | [(R)-1-{6-[(2-Chloro-phenoxy)-hydro...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C28H37ClN3O7P/c1-28(2,3)38-27(34)32-24(18-20-19-31-23-14-8-6-12-21(20)23)26(33)30-16-10-4-5-11-17-37-40(35,36)39-25-15-9-7-13-22(25)29/h6-9,12-15,19,24,31H,4-5,10-11,16-18H2,1-3H3,(H,30,33)(H,32,34)(H,35,36)/t24-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104498
(CHEMBL266842 | [(R)-1-[(S)-1-{3-[({6-[(2-Chloro-ph...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)NCC(=O)NCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H57ClN7O10P/c1-45(2,3)62-44(58)53-38(27-32-25-30-15-6-9-18-35(30)51-32)43(57)52-37(26-31-28-49-36-19-10-7-16-33(31)36)42(56)48-23-14-21-40(54)50-29-41(55)47-22-12-4-5-13-24-61-64(59,60)63-39-20-11-8-17-34(39)46/h6-11,15-20,25,28,37-38,49,51H,4-5,12-14,21-24,26-27,29H2,1-3H3,(H,47,55)(H,48,56)(H,50,54)(H,52,57)(H,53,58)(H,59,60)/t37-,38+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104496
((R)-4-Amino-4-[(R)-1-{12-[(2-chloro-phenoxy)-hydro...)Show SMILES N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C34H48ClN4O8P/c35-27-16-10-12-18-31(27)47-48(44,45)46-22-14-8-6-4-2-1-3-5-7-13-21-37-34(43)30(39-33(42)28(36)19-20-32(40)41)23-25-24-38-29-17-11-9-15-26(25)29/h9-12,15-18,24,28,30,38H,1-8,13-14,19-23,36H2,(H,37,43)(H,39,42)(H,40,41)(H,44,45)/t28-,30-/m1/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
Telomerase reverse transcriptase
(Homo sapiens (Human)) | BDBM50104479
(CHEMBL421541 | [(R)-1-[(S)-1-{12-[(2-Chloro-phenox...)Show SMILES CC(C)(C)OC(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C45H59ClN5O8P/c1-45(2,3)58-44(54)51-40(30-34-28-32-20-12-15-23-37(32)49-34)43(53)50-39(29-33-31-48-38-24-16-13-21-35(33)38)42(52)47-26-18-10-8-6-4-5-7-9-11-19-27-57-60(55,56)59-41-25-17-14-22-36(41)46/h12-17,20-25,28,31,39-40,48-49H,4-11,18-19,26-27,29-30H2,1-3H3,(H,47,52)(H,50,53)(H,51,54)(H,55,56)/t39-,40+/m0/s1 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University
Curated by ChEMBL
| Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines |
Bioorg Med Chem Lett 11: 2581-4 (2001)
BindingDB Entry DOI: 10.7270/Q2XD10Z2 |
More data for this
Ligand-Target Pair | |
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