Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for entry = 50030252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293202 ((S)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293200 (4-cyclopentyl-2-((4-(piperidin-1-ylmethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C22H34N2O2/c1-4-12-23(13-5-1)16-19-8-10-21(11-9-19)26-18-22-17-24(14-15-25-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293189 (4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293202 ((S)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293200 (4-cyclopentyl-2-((4-(piperidin-1-ylmethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C22H34N2O2/c1-4-12-23(13-5-1)16-19-8-10-21(11-9-19)26-18-22-17-24(14-15-25-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293189 (4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293201 ((R)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293192 (4-cyclobutyl-2-((3-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-3-17(14-21-7-10-23-11-8-21)13-19(6-1)25-16-20-15-22(9-12-24-20)18-4-2-5-18/h1,3,6,13,18,20H,2,4-5,7-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293187 (4-isopropyl-2-((4-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-9-12-23-19(14-21)15-24-18-5-3-17(4-6-18)13-20-7-10-22-11-8-20/h3-6,16,19H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293187 (4-isopropyl-2-((4-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-9-12-23-19(14-21)15-24-18-5-3-17(4-6-18)13-20-7-10-22-11-8-20/h3-6,16,19H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293191 (4-isopropyl-2-((3-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2cccc(CN3CCOCC3)c2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-8-11-23-19(14-21)15-24-18-5-3-4-17(12-18)13-20-6-9-22-10-7-20/h3-5,12,16,19H,6-11,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293185 (4-cyclopropyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CC1 Show InChI InChI=1S/C19H28N2O3/c1-5-18(6-2-16(1)13-20-7-10-22-11-8-20)24-15-19-14-21(9-12-23-19)17-3-4-17/h1-2,5-6,17,19H,3-4,7-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293201 ((R)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293184 (4-ethyl-2-((4-(morpholinomethyl)phenoxy)methyl)mor...) Show SMILES CCN1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C18H28N2O3/c1-2-19-9-12-22-18(14-19)15-23-17-5-3-16(4-6-17)13-20-7-10-21-11-8-20/h3-6,18H,2,7-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293192 (4-cyclobutyl-2-((3-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-3-17(14-21-7-10-23-11-8-21)13-19(6-1)25-16-20-15-22(9-12-24-20)18-4-2-5-18/h1,3,6,13,18,20H,2,4-5,7-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293191 (4-isopropyl-2-((3-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2cccc(CN3CCOCC3)c2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-8-11-23-19(14-21)15-24-18-5-3-4-17(12-18)13-20-6-9-22-10-7-20/h3-5,12,16,19H,6-11,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293190 (4-cyclopropyl-2-((3-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CC1 Show InChI InChI=1S/C19H28N2O3/c1-2-16(13-20-6-9-22-10-7-20)12-18(3-1)24-15-19-14-21(8-11-23-19)17-4-5-17/h1-3,12,17,19H,4-11,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	566	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293186 (4-methyl-2-((4-(morpholinomethyl)phenoxy)methyl)mo...) Show SMILES CN1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C17H26N2O3/c1-18-6-11-21-17(13-18)14-22-16-4-2-15(3-5-16)12-19-7-9-20-10-8-19/h2-5,17H,6-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293194 (4-isopropyl-2-(phenoxymethyl)morpholine | CHEMBL51...) Show SMILES CC(C)N1CCOC(COc2ccccc2)C1 Show InChI InChI=1S/C14H21NO2/c1-12(2)15-8-9-16-14(10-15)11-17-13-6-4-3-5-7-13/h3-7,12,14H,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293198 (4-cyclopentyl-2-((2-ethoxyphenoxy)methyl)morpholin...) Show SMILES CCOc1ccccc1OCC1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C18H27NO3/c1-2-20-17-9-5-6-10-18(17)22-14-16-13-19(11-12-21-16)15-7-3-4-8-15/h5-6,9-10,15-16H,2-4,7-8,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293196 (4-cyclobutyl-2-((2-ethoxyphenoxy)methyl)morpholine...) Show SMILES CCOc1ccccc1OCC1CN(CCO1)C1CCC1 Show InChI InChI=1S/C17H25NO3/c1-2-19-16-8-3-4-9-17(16)21-13-15-12-18(10-11-20-15)14-6-5-7-14/h3-4,8-9,14-15H,2,5-7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293195 (2-((2-ethoxyphenoxy)methyl)-4-isopropylmorpholine ...) Show SMILES CCOc1ccccc1OCC1CN(CCO1)C(C)C Show InChI InChI=1S/C16H25NO3/c1-4-18-15-7-5-6-8-16(15)20-12-14-11-17(13(2)3)9-10-19-14/h5-8,13-14H,4,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293193 (2-(phenoxymethyl)morpholine | CHEMBL502684) Show SMILES C(Oc1ccccc1)C1CNCCO1 Show InChI InChI=1S/C11H15NO2/c1-2-4-10(5-3-1)14-9-11-8-12-6-7-13-11/h1-5,11-12H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293197 (4-cyclopropyl-2-((2-ethoxyphenoxy)methyl)morpholin...) Show SMILES CCOc1ccccc1OCC1CN(CCO1)C1CC1 Show InChI InChI=1S/C16H23NO3/c1-2-18-15-5-3-4-6-16(15)20-12-14-11-17(9-10-19-14)13-7-8-13/h3-6,13-14H,2,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair