Compile Data Set for Download or QSAR

Found 46 hits Enz. Inhib. hit(s) with all data for entry = 50047961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198721 (CHEMBL3920504) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H25Cl2FN8O2/c1-19(21-5-3-2-4-6-21)36-31(44)29-25-16-40(28(43)17-41-18-35-38-39-41)15-22(13-20-7-10-24(34)11-8-20)30(25)42(37-29)27-12-9-23(32)14-26(27)33/h2-14,18-19H,15-17H2,1H3,(H,36,44)/b22-13+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198736 (CHEMBL3977281) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)CNS(C)(=O)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H27Cl3N6O4S/c1-18(25-5-3-4-12-34-25)36-30(41)28-23-17-38(27(40)15-35-44(2,42)43)16-20(13-19-6-8-21(31)9-7-19)29(23)39(37-28)26-11-10-22(32)14-24(26)33/h3-14,18,35H,15-17H2,1-2H3,(H,36,41)/b20-13+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198723 (CHEMBL3906628) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CNS(C)(=O)=O)-c1ccc(Cl)cc1)c1ccccn1 |r| Show InChI InChI=1S/C30H28ClFN6O4S/c1-19(26-5-3-4-14-33-26)35-30(40)28-25-18-37(27(39)16-34-43(2,41)42)17-21(15-20-6-10-23(32)11-7-20)29(25)38(36-28)24-12-8-22(31)9-13-24/h3-15,19,34H,16-18H2,1-2H3,(H,35,40)/b21-15+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198724 (CHEMBL3902561) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)CN)cc1 |r| Show InChI InChI=1S/C31H29Cl2N5O3/c1-19(21-6-4-3-5-7-21)35-31(40)29-25-18-37(28(39)16-34)17-22(14-20-8-11-24(41-2)12-9-20)30(25)38(36-29)27-13-10-23(32)15-26(27)33/h3-15,19H,16-18,34H2,1-2H3,(H,35,40)/b22-14+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198725 (CHEMBL3911571) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)c2cc[nH]n2)cc1 |r| Show InChI InChI=1S/C33H28Cl2N6O3/c1-20(22-6-4-3-5-7-22)37-32(42)30-26-19-40(33(43)28-14-15-36-38-28)18-23(16-21-8-11-25(44-2)12-9-21)31(26)41(39-30)29-13-10-24(34)17-27(29)35/h3-17,20H,18-19H2,1-2H3,(H,36,38)(H,37,42)/b23-16+/t20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198726 (CHEMBL3930555) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2N8O2/c1-18(25-4-2-3-13-33-25)36-29(41)26-24-16-39(30(42)28-34-17-35-37-28)15-20(14-19-5-7-21(31)8-6-19)27(24)40(38-26)23-11-9-22(32)10-12-23/h2-14,17-18H,15-16H2,1H3,(H,36,41)(H,34,35,37)/b20-14+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198727 (CHEMBL3905508) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H25Cl2FN6O3/c1-17(24-4-2-3-11-35-24)36-30(42)28-22-16-38(27(41)14-26(34)40)15-19(12-18-5-8-21(33)9-6-18)29(22)39(37-28)25-10-7-20(31)13-23(25)32/h2-13,17H,14-16H2,1H3,(H2,34,40)(H,36,42)/b19-12+/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198728 (CHEMBL3947225) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2FN9O2/c1-18(25-4-2-3-11-34-25)36-30(44)28-23-15-40(27(43)16-41-17-35-38-39-41)14-20(12-19-5-8-22(33)9-6-19)29(23)42(37-28)26-10-7-21(31)13-24(26)32/h2-13,17-18H,14-16H2,1H3,(H,36,44)/b20-12+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198728 (CHEMBL3947225) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2FN9O2/c1-18(25-4-2-3-11-34-25)36-30(44)28-23-15-40(27(43)16-41-17-35-38-39-41)14-20(12-19-5-8-22(33)9-6-19)29(23)42(37-28)26-10-7-21(31)13-24(26)32/h2-13,17-18H,14-16H2,1H3,(H,36,44)/b20-12+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.61E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198729 (CHEMBL3932505) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)c2nc[nH]n2)cc1 |r| Show InChI InChI=1S/C32H27Cl2N7O3/c1-19(21-6-4-3-5-7-21)37-31(42)28-25-17-40(32(43)30-35-18-36-38-30)16-22(14-20-8-11-24(44-2)12-9-20)29(25)41(39-28)27-13-10-23(33)15-26(27)34/h3-15,18-19H,16-17H2,1-2H3,(H,37,42)(H,35,36,38)/b22-14+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198727 (CHEMBL3905508) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H25Cl2FN6O3/c1-17(24-4-2-3-11-35-24)36-30(42)28-22-16-38(27(41)14-26(34)40)15-19(12-18-5-8-21(33)9-6-18)29(22)39(37-28)25-10-7-20(31)13-23(25)32/h2-13,17H,14-16H2,1H3,(H2,34,40)(H,36,42)/b19-12+/t17-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198730 (CHEMBL3950659) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnn2)cc1 |r| Show InChI InChI=1S/C33H29Cl2N7O3/c1-21(23-6-4-3-5-7-23)37-33(44)31-27-19-40(30(43)20-41-15-14-36-39-41)18-24(16-22-8-11-26(45-2)12-9-22)32(27)42(38-31)29-13-10-25(34)17-28(29)35/h3-17,21H,18-20H2,1-2H3,(H,37,44)/b24-16+/t21-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198731 (CHEMBL3951226) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CC(O)=O)cc1 |r| Show InChI InChI=1S/C31H27Cl2N5O5/c1-18(25-5-3-4-12-34-25)35-31(42)29-23-17-37(27(39)15-28(40)41)16-20(13-19-6-9-22(43-2)10-7-19)30(23)38(36-29)26-11-8-21(32)14-24(26)33/h3-14,18H,15-17H2,1-2H3,(H,35,42)(H,40,41)/b20-13+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198732 (CHEMBL3976516) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)c(Cl)c1)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2FN9O2/c1-18(26-4-2-3-11-34-26)36-30(44)28-23-15-40(27(43)16-41-17-35-38-39-41)14-20(12-19-5-7-21(33)8-6-19)29(23)42(37-28)22-9-10-24(31)25(32)13-22/h2-13,17-18H,14-16H2,1H3,(H,36,44)/b20-12+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198733 (CHEMBL3896570) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CS(N)(=O)=O)cc1 |r| Show InChI InChI=1S/C30H28Cl2N6O5S/c1-18(25-5-3-4-12-34-25)35-30(40)28-23-16-37(27(39)17-44(33,41)42)15-20(13-19-6-9-22(43-2)10-7-19)29(23)38(36-28)26-11-8-21(31)14-24(26)32/h3-14,18H,15-17H2,1-2H3,(H,35,40)(H2,33,41,42)/b20-13+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198734 (CHEMBL3921605) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H27Cl3N4O4/c1-18(20-5-3-2-4-6-20)35-30(41)28-24-16-37(31(42)27(40)17-39)15-21(13-19-7-9-22(32)10-8-19)29(24)38(36-28)26-12-11-23(33)14-25(26)34/h2-14,18,27,39-40H,15-17H2,1H3,(H,35,41)/b21-13+/t18-,27+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198729 (CHEMBL3932505) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)c2nc[nH]n2)cc1 |r| Show InChI InChI=1S/C32H27Cl2N7O3/c1-19(21-6-4-3-5-7-21)37-31(42)28-25-17-40(32(43)30-35-18-36-38-30)16-22(14-20-8-11-24(44-2)12-9-20)29(25)41(39-28)27-13-10-23(33)15-26(27)34/h3-15,18-19H,16-17H2,1-2H3,(H,37,42)(H,35,36,38)/b22-14+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198735 (CHEMBL3960011) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H24Cl2FN7O2/c1-18(20-5-3-2-4-6-20)37-30(42)27-24-16-40(31(43)29-35-17-36-38-29)15-21(13-19-7-10-23(34)11-8-19)28(24)41(39-27)26-12-9-22(32)14-25(26)33/h2-14,17-18H,15-16H2,1H3,(H,37,42)(H,35,36,38)/b21-13+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198724 (CHEMBL3902561) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)CN)cc1 |r| Show InChI InChI=1S/C31H29Cl2N5O3/c1-19(21-6-4-3-5-7-21)35-31(40)29-25-18-37(28(39)16-34)17-22(14-20-8-11-24(41-2)12-9-20)30(25)38(36-29)27-13-10-23(32)15-26(27)33/h3-15,19H,16-18,34H2,1-2H3,(H,35,40)/b22-14+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198732 (CHEMBL3976516) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)c(Cl)c1)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2FN9O2/c1-18(26-4-2-3-11-34-26)36-30(44)28-23-15-40(27(43)16-41-17-35-38-39-41)14-20(12-19-5-7-21(33)8-6-19)29(23)42(37-28)22-9-10-24(31)25(32)13-22/h2-13,17-18H,14-16H2,1H3,(H,36,44)/b20-12+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.66E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198723 (CHEMBL3906628) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CNS(C)(=O)=O)-c1ccc(Cl)cc1)c1ccccn1 |r| Show InChI InChI=1S/C30H28ClFN6O4S/c1-19(26-5-3-4-14-33-26)35-30(40)28-25-18-37(27(39)16-34-43(2,41)42)17-21(15-20-6-10-23(32)11-7-20)29(25)38(36-28)24-12-8-22(31)9-13-24/h3-15,19,34H,16-18H2,1-2H3,(H,35,40)/b21-15+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198736 (CHEMBL3977281) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)CNS(C)(=O)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H27Cl3N6O4S/c1-18(25-5-3-4-12-34-25)36-30(41)28-23-17-38(27(40)15-35-44(2,42)43)16-20(13-19-6-8-21(31)9-7-19)29(23)39(37-28)26-11-10-22(32)14-24(26)33/h3-14,18,35H,15-17H2,1-2H3,(H,36,41)/b20-13+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198733 (CHEMBL3896570) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CS(N)(=O)=O)cc1 |r| Show InChI InChI=1S/C30H28Cl2N6O5S/c1-18(25-5-3-4-12-34-25)35-30(40)28-23-16-37(27(39)17-44(33,41)42)15-20(13-19-6-9-22(43-2)10-7-19)29(23)38(36-28)26-11-8-21(31)14-24(26)32/h3-14,18H,15-17H2,1-2H3,(H,35,40)(H2,33,41,42)/b20-13+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198737 (CHEMBL3939540) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2cnnn2)cc1 |r| Show InChI InChI=1S/C32H28Cl2N8O3/c1-20(22-6-4-3-5-7-22)36-32(44)30-26-17-40(29(43)18-41-19-35-38-39-41)16-23(14-21-8-11-25(45-2)12-9-21)31(26)42(37-30)28-13-10-24(33)15-27(28)34/h3-15,19-20H,16-18H2,1-2H3,(H,36,44)/b23-14+/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198725 (CHEMBL3911571) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)c2cc[nH]n2)cc1 |r| Show InChI InChI=1S/C33H28Cl2N6O3/c1-20(22-6-4-3-5-7-22)37-32(42)30-26-19-40(33(43)28-14-15-36-38-28)18-23(16-21-8-11-25(44-2)12-9-21)31(26)41(39-30)29-13-10-24(34)17-27(29)35/h3-17,20H,18-19H2,1-2H3,(H,36,38)(H,37,42)/b23-16+/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.66E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198735 (CHEMBL3960011) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H24Cl2FN7O2/c1-18(20-5-3-2-4-6-20)37-30(42)27-24-16-40(31(43)29-35-17-36-38-29)15-21(13-19-7-10-23(34)11-8-19)28(24)41(39-27)26-12-9-22(32)14-25(26)33/h2-14,17-18H,15-16H2,1H3,(H,37,42)(H,35,36,38)/b21-13+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198731 (CHEMBL3951226) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CC(O)=O)cc1 |r| Show InChI InChI=1S/C31H27Cl2N5O5/c1-18(25-5-3-4-12-34-25)35-31(42)29-23-17-37(27(39)15-28(40)41)16-20(13-19-6-9-22(43-2)10-7-19)30(23)38(36-29)26-11-8-21(32)14-24(26)33/h3-14,18H,15-17H2,1-2H3,(H,35,42)(H,40,41)/b20-13+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198738 (CHEMBL3985361) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H26Cl3N5O4/c1-17(24-4-2-3-11-34-24)35-29(41)27-22-15-37(30(42)26(40)16-39)14-19(12-18-5-7-20(31)8-6-18)28(22)38(36-27)25-10-9-21(32)13-23(25)33/h2-13,17,26,39-40H,14-16H2,1H3,(H,35,41)/b19-12+/t17-,26+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198739 (CHEMBL3915613) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)Cn1cncn1)-c1ccc(Cl)c(Cl)c1)c1ccccn1 |r| Show InChI InChI=1S/C31H25Cl3N8O2/c1-19(27-4-2-3-11-36-27)38-31(44)29-24-15-40(28(43)16-41-18-35-17-37-41)14-21(12-20-5-7-22(32)8-6-20)30(24)42(39-29)23-9-10-25(33)26(34)13-23/h2-13,17-19H,14-16H2,1H3,(H,38,44)/b21-12+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198726 (CHEMBL3930555) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccn1 |r| Show InChI InChI=1S/C30H24Cl2N8O2/c1-18(25-4-2-3-13-33-25)36-29(41)26-24-16-39(30(42)28-34-17-35-37-28)15-20(14-19-5-7-21(31)8-6-19)27(24)40(38-26)23-11-9-22(32)10-12-23/h2-14,17-18H,15-16H2,1H3,(H,36,41)(H,34,35,37)/b20-14+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198734 (CHEMBL3921605) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H27Cl3N4O4/c1-18(20-5-3-2-4-6-20)35-30(41)28-24-16-37(31(42)27(40)17-39)15-21(13-19-7-9-22(32)10-8-19)29(24)38(36-28)26-12-11-23(33)14-25(26)34/h2-14,18,27,39-40H,15-17H2,1H3,(H,35,41)/b21-13+/t18-,27+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.91E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198740 (CHEMBL3924597) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CCS(N)(=O)=O)cc1 |r| Show InChI InChI=1S/C31H30Cl2N6O5S/c1-19(26-5-3-4-13-35-26)36-31(41)29-24-18-38(28(40)12-14-45(34,42)43)17-21(15-20-6-9-23(44-2)10-7-20)30(24)39(37-29)27-11-8-22(32)16-25(27)33/h3-11,13,15-16,19H,12,14,17-18H2,1-2H3,(H,36,41)(H2,34,42,43)/b21-15+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198738 (CHEMBL3985361) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)[C@@H](O)CO)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C30H26Cl3N5O4/c1-17(24-4-2-3-11-34-24)35-29(41)27-22-15-37(30(42)26(40)16-39)14-19(12-18-5-7-20(31)8-6-18)28(22)38(36-27)25-10-9-21(32)13-23(25)33/h2-13,17,26,39-40H,14-16H2,1H3,(H,35,41)/b19-12+/t17-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198741 (CHEMBL3977295) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C31H25ClFN7O2/c1-19(21-5-3-2-4-6-21)36-30(41)27-26-17-39(31(42)29-34-18-35-37-29)16-22(15-20-7-11-24(33)12-8-20)28(26)40(38-27)25-13-9-23(32)10-14-25/h2-15,18-19H,16-17H2,1H3,(H,36,41)(H,34,35,37)/b22-15+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198721 (CHEMBL3920504) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)Cn1cnnn1)-c1ccc(Cl)cc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C31H25Cl2FN8O2/c1-19(21-5-3-2-4-6-21)36-31(44)29-25-16-40(28(43)17-41-18-35-38-39-41)15-22(13-20-7-10-24(34)11-8-20)30(25)42(37-29)27-12-9-23(32)14-26(27)33/h2-14,18-19H,15-17H2,1H3,(H,36,44)/b22-13+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198743 (CHEMBL3893586) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnc2)cc1 |r| Show InChI InChI=1S/C34H30Cl2N6O3/c1-22(24-6-4-3-5-7-24)38-34(44)32-28-19-41(31(43)20-40-15-14-37-21-40)18-25(16-23-8-11-27(45-2)12-9-23)33(28)42(39-32)30-13-10-26(35)17-29(30)36/h3-17,21-22H,18-20H2,1-2H3,(H,38,44)/b25-16+/t22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198742 (CHEMBL3933518) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CCC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C31H27Cl2FN6O3/c1-18(25-4-2-3-13-36-25)37-31(43)29-23-17-39(28(42)12-11-27(35)41)16-20(14-19-5-8-22(34)9-6-19)30(23)40(38-29)26-10-7-21(32)15-24(26)33/h2-10,13-15,18H,11-12,16-17H2,1H3,(H2,35,41)(H,37,43)/b20-14+/t18-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198737 (CHEMBL3939540) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2cnnn2)cc1 |r| Show InChI InChI=1S/C32H28Cl2N8O3/c1-20(22-6-4-3-5-7-22)36-32(44)30-26-17-40(29(43)18-41-19-35-38-39-41)16-23(14-21-8-11-25(45-2)12-9-21)31(26)42(37-30)28-13-10-24(33)15-27(28)34/h3-15,19-20H,16-18H2,1-2H3,(H,36,44)/b23-14+/t20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198741 (CHEMBL3977295) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C31H25ClFN7O2/c1-19(21-5-3-2-4-6-21)36-30(41)27-26-17-39(31(42)29-34-18-35-37-29)16-22(15-20-7-11-24(33)12-8-20)28(26)40(38-27)25-13-9-23(32)10-14-25/h2-15,18-19H,16-17H2,1H3,(H,36,41)(H,34,35,37)/b22-15+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198739 (CHEMBL3915613) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)Cn1cncn1)-c1ccc(Cl)c(Cl)c1)c1ccccn1 |r| Show InChI InChI=1S/C31H25Cl3N8O2/c1-19(27-4-2-3-11-36-27)38-31(44)29-24-15-40(28(43)16-41-18-35-17-37-41)14-21(12-20-5-7-22(32)8-6-20)30(24)42(39-29)23-9-10-25(33)26(34)13-23/h2-13,17-19H,14-16H2,1H3,(H,38,44)/b21-12+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198742 (CHEMBL3933518) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(F)cc1)C(=O)CCC(N)=O)-c1ccc(Cl)cc1Cl)c1ccccn1 |r| Show InChI InChI=1S/C31H27Cl2FN6O3/c1-18(25-4-2-3-13-36-25)37-31(43)29-23-17-39(28(42)12-11-27(35)41)16-20(14-19-5-8-22(34)9-6-19)30(23)40(38-29)26-10-7-21(32)15-24(26)33/h2-10,13-15,18H,11-12,16-17H2,1H3,(H2,35,41)(H,37,43)/b20-14+/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198730 (CHEMBL3950659) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnn2)cc1 |r| Show InChI InChI=1S/C33H29Cl2N7O3/c1-21(23-6-4-3-5-7-23)37-33(44)31-27-19-40(30(43)20-41-15-14-36-39-41)18-24(16-22-8-11-26(45-2)12-9-22)32(27)42(38-31)29-13-10-25(34)17-28(29)35/h3-17,21H,18-20H2,1-2H3,(H,37,44)/b24-16+/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198722 (CHEMBL3915676) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C31H25Cl2N7O2/c1-19(21-5-3-2-4-6-21)36-30(41)27-26-17-39(31(42)29-34-18-35-37-29)16-22(15-20-7-9-23(32)10-8-20)28(26)40(38-27)25-13-11-24(33)12-14-25/h2-15,18-19H,16-17H2,1H3,(H,36,41)(H,34,35,37)/b22-15+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198743 (CHEMBL3893586) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccc2)C(=O)Cn2ccnc2)cc1 |r| Show InChI InChI=1S/C34H30Cl2N6O3/c1-22(24-6-4-3-5-7-24)38-34(44)32-28-19-41(31(43)20-40-15-14-37-21-40)18-25(16-23-8-11-27(45-2)12-9-23)33(28)42(39-32)30-13-10-26(35)17-29(30)36/h3-17,21-22H,18-20H2,1-2H3,(H,38,44)/b25-16+/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198740 (CHEMBL3924597) Show SMILES COc1ccc(\C=C2/CN(Cc3c(nn(c23)-c2ccc(Cl)cc2Cl)C(=O)N[C@H](C)c2ccccn2)C(=O)CCS(N)(=O)=O)cc1 |r| Show InChI InChI=1S/C31H30Cl2N6O5S/c1-19(26-5-3-4-13-35-26)36-31(41)29-24-18-38(28(40)12-14-45(34,42)43)17-21(15-20-6-9-23(44-2)10-7-20)30(24)39(37-29)27-11-8-22(32)16-25(27)33/h3-11,13,15-16,19H,12,14,17-18H2,1-2H3,(H,36,41)(H2,34,42,43)/b21-15+/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB1 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198722 (CHEMBL3915676) Show SMILES C[C@@H](NC(=O)c1nn(c2c1CN(C\C2=C/c1ccc(Cl)cc1)C(=O)c1nc[nH]n1)-c1ccc(Cl)cc1)c1ccccc1 |r| Show InChI InChI=1S/C31H25Cl2N7O2/c1-19(21-5-3-2-4-6-21)36-30(41)27-26-17-39(31(42)29-34-18-35-37-29)16-22(15-20-7-9-23(32)10-8-20)28(26)40(38-27)25-13-11-24(33)12-14-25/h2-15,18-19H,16-17H2,1H3,(H,36,41)(H,34,35,37)/b22-15+/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human CB2 receptor transfected in HEK293 cells assessed as increase of forskolin-induced cAMP production incubated for 30...				Bioorg Med Chem Lett 26: 5597-5601 (2016) Article DOI: 10.1016/j.bmcl.2016.09.026 BindingDB Entry DOI: 10.7270/Q2GM898H
					More data for this Ligand-Target Pair