Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5140 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5146 (5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5138 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5145 ((5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5134 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5144 ((5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-5-{[3-methy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5127 (3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5139 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(3,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5130 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5137 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5141 (5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5129 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5128 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5142 (5-{[(5Z)-4-[(4-chloro-2-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5126 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-di...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5133 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5124 (3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5125 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5135 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({4-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5138 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5140 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5136 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5142 (5-{[(5Z)-4-[(4-chloro-2-fluorophenyl)amino]-6-oxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5143 ((5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5139 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(3,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.63E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5144 ((5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-5-{[3-methy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5145 ((5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5143 ((5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5125 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5146 (5-{[(5Z)-4-[(1-benzyl-1H-indol-5-yl)amino]-6-oxo-5...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5132 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-7-meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM5142 (5-{[(5Z)-4-[(4-chloro-2-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5131 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.82E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5128 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.92E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM5145 ((5Z)-4-[(1-benzyl-1H-indazol-5-yl)amino]-5-{[3-met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5132 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-7-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5126 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-[(3,5-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5123 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-(1H-pyrr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5124 (3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-o...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5127 (3-(5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-o...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5129 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5130 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5133 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-{[3-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5134 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5135 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({4-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5136 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({3-meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5137 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-({5-[(4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5141 (5-{[(5Z)-4-[(3-ethynylphenyl)amino]-6-oxo-5H,6H,7H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM5147 ((5Z)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-py...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM5123 ((5Z)-4-[(3-chloro-4-fluorophenyl)amino]-5-(1H-pyrr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
SUGEN, Inc. | Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well... | Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N | |||||||||||
More data for this Ligand-Target Pair |
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