Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343301![]() (2-((4-(4-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343305![]() (2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 91 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343299![]() (2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50277957![]() ((R)-3-((2',4'-difluorobiphenyl-4-yl)methyl)-5-meth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 323 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343317![]() (1-methyl-2-(((1R,5S)-3-(4-(trifluoromethyl)phenyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 355 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343308![]() (1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 404 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343295![]() (2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 426 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343306![]() (1-methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 561 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343316![]() (CHEMBL1774224 | cis-1-methyl-2-(((2R,4R)-2-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 589 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343309![]() (1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 671 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343314![]() (2-((4-(2-Fluoro-4-(trifluoromethoxy)phenyl)piperid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343321![]() (CHEMBL1774229 | cis-2-(((3R,4R)-4-(4-chloro-2-fluo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343313![]() (2-((4-(2-Fluoro-4-(trifluoromethyl)phenyl)piperidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50277955![]() ((R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343312![]() (2-((4-(2-Methoxy-4-(trifluoromethyl)phenyl)piperid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343318![]() ((S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343319![]() (CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343320![]() (CHEMBL1774228 | cis-1-methyl-2-(((3S,4S)-3-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343319![]() (CHEMBL1774227 | cis-1-methyl-2-(((3R,4R)-3-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50277956![]() ((R)-3-((2'-fluoro-4'-(trifluoromethoxy)biphenyl-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50278007![]() ((R)-3-((6-(2-fluoro-4-(trifluoromethoxy)phenyl)pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | >3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50278009![]() ((R)-3-((6-(3,4-difluorophenyl)pyridin-3-yl)methyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50277846![]() ((5R)-3-(4-(1-cyclohexylethoxy)benzyl)-5-methyloxaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human 5HT2A receptor | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343327![]() (CHEMBL1774235 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >4.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343323![]() (CHEMBL1774231 | cis-2-(((3R,4R)-4-(2-methoxy-4-(tr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50343325![]() (CHEMBL1774233 | cis-2-(((3R,4R)-4-(2-fluoro-4-(tri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation counting | J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277806![]() ((5S)-3-(4-(1-cyclohexylethoxy)benzyl)-5-methyloxaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 22.1 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277920![]() ((R)-3-((2'-ethoxybiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277883![]() ((R)-3-((2'-chlorobiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277955![]() ((R)-3-((3'-chloro-4'-fluorobiphenyl-4-yl)methyl)-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277956![]() ((R)-3-((2'-fluoro-4'-(trifluoromethoxy)biphenyl-4-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277880![]() ((R)-3-((2'-fluorobiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277917![]() ((R)-3-((2'-methoxybiphenyl-4-yl)methyl)-5-methylox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 41 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277919![]() ((R)-3-((4'-methoxybiphenyl-4-yl)methyl)-5-methylox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 53 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277957![]() ((R)-3-((2',4'-difluorobiphenyl-4-yl)methyl)-5-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277771![]() (3-(4-(1-cyclohexylethoxy)benzyl)-1,3-oxazinan-2-on...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 75 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277916![]() ((R)-3-((4'-chlorobiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 76 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277882![]() ((R)-3-((4'-fluorobiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 84 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277878![]() ((5R)-3-((6-(1-cyclohexylethoxy)pyridin-3-yl)methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 88 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277953![]() ((R)-3-((4'-ethoxybiphenyl-4-yl)methyl)-5-methyloxa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 97 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277770![]() (3-(4-(cyclohexylmethoxy)benzyl)-1,3-oxazinan-2-one...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 117 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277805![]() (3-(4-(cyclohexylmethoxy)benzyl)-5-methyloxazolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50278009![]() ((R)-3-((6-(3,4-difluorophenyl)pyridin-3-yl)methyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50278006![]() ((R)-5-methyl-3-(4-(pyrimidin-5-yl)benzyl)oxazolidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.38E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277958![]() ((R)-5-methyl-3-(4-(pyridin-4-yl)benzyl)oxazolidin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.79E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50278054![]() ((R)-3-((2'-((dimethylamino)methyl)biphenyl-4-yl)me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.36E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50278005![]() ((R)-5-methyl-3-(4-(pyridin-3-yl)benzyl)oxazolidin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.55E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277844![]() (3-(4-(pyridin-3-ylmethoxy)benzyl)-1,3-oxazinan-2-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277845![]() (5-methyl-3-(4-(tetrahydro-2H-pyran-4-yloxy)benzyl)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50277847![]() ((R)-3-(4-((cyclohexyl(methyl)amino)methyl)benzyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate | Bioorg Med Chem Lett 19: 2524-9 (2009) Article DOI: 10.1016/j.bmcl.2009.03.032 BindingDB Entry DOI: 10.7270/Q2F18ZK7 | |||||||||||
More data for this Ligand-Target Pair |
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