Compile Data Set for Download or QSAR

Found 1645 hits with Last Name = 'curry' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074509 (CHEMBL354886 | [3-(2,4-Dibromo-phenyl)-5-methyl-3H...) Show SMILES CCCC(CCC)Nc1nc(C)nc2n(nnc12)-c1ccc(Br)cc1Br Show InChI InChI=1S/C18H22Br2N6/c1-4-6-13(7-5-2)23-17-16-18(22-11(3)21-17)26(25-24-16)15-9-8-12(19)10-14(15)20/h8-10,13H,4-7H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074501 (Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-ph...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(C)c(C)c12)-c1c(C)cc(C)cc1C |(4.9,1.82,;3.57,2.56,;2.24,1.79,;.91,2.55,;-.44,1.78,;-1.76,2.55,;-3.1,1.78,;-.42,.25,;-1.75,-.52,;-1.75,-2.06,;-3.08,-2.83,;-.42,-2.83,;.91,-2.06,;2.38,-2.54,;3.31,-1.29,;4.85,-1.29,;2.38,-.03,;2.86,1.43,;.91,-.52,;2.86,-4.02,;4.37,-4.33,;5.39,-3.17,;4.85,-5.78,;3.82,-6.93,;4.31,-8.4,;2.32,-6.61,;1.84,-5.14,;.33,-4.82,)| Show InChI InChI=1S/C24H34N4/c1-9-11-12-27(10-2)23-21-18(6)19(7)28(24(21)26-20(8)25-23)22-16(4)13-15(3)14-17(22)5/h13-14H,9-12H2,1-8H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074492 (CHEMBL168554 | [9-(2-Bromo-4-isopropyl-phenyl)-2,8...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(C)nc12)-c1ccc(cc1Br)C(C)C |(12.64,1.78,;12.64,.23,;11.31,-.54,;11.31,-2.08,;9.99,-2.85,;8.64,-2.08,;7.32,-2.85,;9.99,-4.38,;8.64,-5.15,;8.64,-6.69,;7.31,-7.46,;9.99,-7.46,;11.31,-6.69,;12.76,-7.15,;13.67,-5.92,;15.21,-5.94,;12.76,-4.68,;11.31,-5.15,;13.39,-8.57,;12.49,-9.81,;13.11,-11.22,;14.65,-11.38,;15.56,-10.13,;14.93,-8.73,;15.84,-7.48,;15.27,-12.8,;16.79,-12.97,;14.35,-14.04,)| Show InChI InChI=1S/C22H30BrN5/c1-7-9-12-27(8-2)21-20-22(25-15(5)24-21)28(16(6)26-20)19-11-10-17(14(3)4)13-18(19)23/h10-11,13-14H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074465 (CHEMBL354982 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(nc12)C(F)(F)F)-c1ccc(cc1Br)C(C)C |(12.23,1.79,;12.23,.23,;10.9,-.54,;10.9,-2.08,;9.57,-2.85,;8.22,-2.08,;6.89,-2.85,;9.57,-4.39,;8.22,-5.16,;8.22,-6.7,;6.88,-7.47,;9.57,-7.47,;10.9,-6.7,;12.35,-7.17,;13.26,-5.93,;12.35,-4.69,;10.9,-5.16,;14.8,-5.95,;16.34,-5.96,;14.79,-7.47,;14.8,-4.41,;12.68,-8.68,;11.55,-9.71,;11.88,-11.21,;13.33,-11.69,;14.47,-10.65,;14.15,-9.15,;15.41,-8.29,;13.66,-13.21,;12.51,-14.24,;15.13,-13.7,)| Show InChI InChI=1S/C22H27BrF3N5/c1-6-8-11-30(7-2)19-18-20(28-14(5)27-19)31(21(29-18)22(24,25)26)17-10-9-15(13(3)4)12-16(17)23/h9-10,12-13H,6-8,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074500 (3-(2-Bromo-4-isopropyl-phenyl)-7-(1-ethyl-pentylox...) Show SMILES CCCCC(CC)Oc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5O/c1-6-8-9-16(7-2)28-21-19-20(23-14(5)24-21)27(26-25-19)18-11-10-15(13(3)4)12-17(18)22/h10-13,16H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076613 (CHEMBL367253 | [9-(2-Bromo-4-isopropyl-phenyl)-8-m...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(OC)nc12)-c1ccc(cc1Br)C(C)C |(5.24,-4.86,;5.24,-6.4,;6.57,-7.17,;6.59,-8.71,;7.92,-9.48,;9.28,-8.71,;9.25,-7.17,;7.95,-11.02,;6.61,-11.79,;6.61,-13.33,;5.26,-14.1,;7.95,-14.1,;9.28,-13.33,;10.75,-13.8,;11.66,-12.54,;13.2,-12.54,;13.74,-13.32,;10.75,-11.3,;9.28,-11.79,;11.24,-15.24,;10.21,-16.39,;10.7,-17.86,;12.21,-18.16,;13.24,-17.02,;12.75,-15.55,;13.83,-14.45,;12.7,-19.63,;11.67,-20.78,;14.2,-19.94,)| Show InChI InChI=1S/C22H30BrN5O/c1-7-9-12-27(8-2)20-19-21(25-15(5)24-20)28(22(26-19)29-6)18-11-10-16(14(3)4)13-17(18)23/h10-11,13-14H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...				Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076602 (CHEMBL368772 | [9-(2-Bromo-4-isopropyl-phenyl)-8-c...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(Cl)nc12)-c1ccc(cc1Br)C(C)C |(-1.35,.74,;-1.35,-.8,;.01,-1.57,;.01,-3.11,;1.36,-3.87,;2.69,-3.1,;2.69,-1.56,;1.36,-5.41,;.03,-6.18,;.03,-7.73,;-1.3,-8.5,;1.36,-8.5,;2.71,-7.71,;4.18,-8.17,;5.07,-6.94,;6.61,-6.93,;4.16,-5.69,;2.69,-6.18,;4.65,-9.64,;3.62,-10.79,;4.11,-12.26,;5.63,-12.56,;6.66,-11.41,;6.17,-9.94,;7.26,-8.85,;6.1,-14.02,;5.09,-15.17,;7.61,-14.33,)| Show InChI InChI=1S/C21H27BrClN5/c1-6-8-11-27(7-2)19-18-20(25-14(5)24-19)28(21(23)26-18)17-10-9-15(13(3)4)12-16(17)22/h9-10,12-13H,6-8,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...				Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50058163 (Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...) Show SMILES CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c1c(C)cc(C)cc1C |(-10.62,2.69,;-9.29,3.46,;-7.95,2.7,;-6.62,3.48,;-5.28,2.71,;-3.95,3.49,;-3.96,5.03,;-5.27,1.17,;-6.6,.4,;-6.6,-1.14,;-7.94,-1.91,;-5.27,-1.91,;-3.92,-1.14,;-2.44,-1.61,;-1.54,-.35,;-2.46,.9,;-1.99,2.37,;-3.93,.41,;-1.96,-3.07,;-2.99,-4.22,;-4.49,-3.91,;-2.5,-5.68,;-.99,-5.99,;-.51,-7.46,;.03,-4.83,;-.46,-3.38,;.56,-2.22,)| Show InChI InChI=1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074482 (3-(2-Bromo-4-isopropyl-phenyl)-7-(1-methoxymethyl-...) Show SMILES CCC(COC)Oc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C19H24BrN5O2/c1-6-14(10-26-5)27-19-17-18(21-12(4)22-19)25(24-23-17)16-8-7-13(11(2)3)9-15(16)20/h7-9,11,14H,6,10H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074470 (3-(2-Bromo-4-isopropyl-phenyl)-7-(1-ethyl-propoxy)...) Show SMILES CCC(CC)Oc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C19H24BrN5O/c1-6-14(7-2)26-19-17-18(21-12(5)22-19)25(24-23-17)16-9-8-13(11(3)4)10-15(16)20/h8-11,14H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074349 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-(1-ethyl-pro...) Show SMILES CCC(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H30BrN3/c1-7-16(8-2)19-12-15(6)23-21(24-19)25(9-3)20-11-10-17(14(4)5)13-18(20)22/h10-14,16H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074468 (Butyl-ethyl-[3-(4-isopropyl-2-methylsulfanyl-pheny...) Show SMILES CCCCN(CC)c1cc(C)nc2n(nnc12)-c1ccc(cc1SC)C(C)C Show InChI InChI=1S/C22H31N5S/c1-7-9-12-26(8-2)19-13-16(5)23-22-21(19)24-25-27(22)18-11-10-17(15(3)4)14-20(18)28-6/h10-11,13-15H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074474 (CHEMBL166669 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES CCCC(CC)Nc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H27BrN6/c1-6-8-15(7-2)24-19-18-20(23-13(5)22-19)27(26-25-18)17-10-9-14(12(3)4)11-16(17)21/h9-12,15H,6-8H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074459 (9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-pentylox...) Show SMILES CCCCC(CC)Oc1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H29BrN4O/c1-6-8-9-17(7-2)28-22-20-21(25-15(5)26-22)27(13-24-20)19-11-10-16(14(3)4)12-18(19)23/h10-14,17H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076608 (7-(Butyl-ethyl-amino)-1,5-dimethyl-3-phenyl-1,3-di...) Show SMILES CCCCN(CC)c1cc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)n(C)c12 |(-6.64,.67,;-6.63,-.87,;-5.3,-1.64,;-5.29,-3.18,;-3.94,-3.95,;-2.61,-3.18,;-2.61,-1.64,;-3.94,-5.49,;-5.27,-6.26,;-5.27,-7.8,;-6.6,-8.57,;-3.94,-8.57,;-2.59,-7.8,;-1.12,-8.27,;-.65,-9.71,;-1.67,-10.86,;-1.18,-12.33,;.33,-12.63,;1.36,-11.49,;.87,-10.02,;1.96,-8.92,;.82,-14.1,;2.33,-14.4,;-.2,-15.24,;-.21,-7.01,;1.33,-7.01,;-1.14,-5.77,;-.67,-4.3,;-2.59,-6.26,)| Show InChI InChI=1S/C23H31BrN4O/c1-7-9-12-27(8-2)20-13-16(5)25-22-21(20)26(6)23(29)28(22)19-11-10-17(15(3)4)14-18(19)24/h10-11,13-15H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...				Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074354 (CHEMBL168131 | N,N-Diallyl-N'-(2-bromo-4-dimethyla...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)N(C)C Show InChI InChI=1S/C20H27BrN6/c1-7-12-26(13-8-2)19-22-15(4)23-20(24-19)27(9-3)18-11-10-16(25(5)6)14-17(18)21/h7-8,10-11,14H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074458 (CHEMBL9633 | [3-(2-Bromo-4,6-dimethoxy-phenyl)-5-m...) Show SMILES CCCCN(CC)c1nc(C)nc2n(nnc12)-c1c(Br)cc(OC)cc1OC |(13.26,-.73,;11.93,.04,;10.59,-.73,;9.26,.02,;7.91,-.75,;6.58,.02,;5.24,-.76,;7.92,-2.29,;6.59,-3.06,;6.59,-4.61,;5.24,-5.38,;7.92,-5.38,;9.26,-4.6,;10.73,-5.08,;11.64,-3.83,;10.73,-2.58,;9.26,-3.06,;11.2,-6.55,;12.7,-6.86,;13.73,-5.71,;13.19,-8.31,;12.16,-9.47,;12.63,-10.95,;11.6,-12.09,;10.64,-9.15,;10.17,-7.69,;8.66,-7.37,;7.63,-8.52,)| Show InChI InChI=1S/C19H25BrN6O2/c1-6-8-9-25(7-2)18-16-19(22-12(3)21-18)26(24-23-16)17-14(20)10-13(27-4)11-15(17)28-5/h10-11H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074452 (CHEMBL169952 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES CCCCC(CC)Nc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H29BrN6/c1-6-8-9-16(7-2)25-20-19-21(24-14(5)23-20)28(27-26-19)18-11-10-15(13(3)4)12-17(18)22/h10-13,16H,6-9H2,1-5H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074453 (CHEMBL171202 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES CCCCN(CC)c1cc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-6-8-11-26(7-2)19-12-15(5)23-21-20(19)24-25-27(21)18-10-9-16(14(3)4)13-17(18)22/h9-10,12-14H,6-8,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074496 (Butyl-[9-(2-chloro-4,6-dimethoxy-phenyl)-2,8-dimet...) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(C)nc12)-c1c(Cl)cc(OC)cc1OC |(12.72,1.93,;12.72,.39,;11.39,-.38,;11.39,-1.94,;10.06,-2.71,;8.73,-1.94,;7.38,-2.71,;10.06,-4.25,;8.73,-5.02,;8.73,-6.56,;7.38,-7.33,;10.06,-7.33,;11.39,-6.56,;12.86,-7.03,;13.75,-5.79,;15.29,-5.79,;12.86,-4.53,;11.39,-5.02,;13.49,-8.43,;15.01,-8.59,;15.92,-7.35,;15.64,-10.01,;14.73,-11.25,;15.36,-12.68,;16.9,-12.86,;13.21,-11.09,;12.58,-9.69,;11.04,-9.53,;10.13,-10.79,)| Show InChI InChI=1S/C21H28ClN5O2/c1-7-9-10-26(8-2)20-18-21(24-13(3)23-20)27(14(4)25-18)19-16(22)11-15(28-5)12-17(19)29-6/h11-12H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074542 (9-(2-Bromo-4-isopropyl-phenyl)-6-(1-ethyl-propoxy)...) Show SMILES CCC(CC)Oc1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H25BrN4O/c1-6-15(7-2)26-20-18-19(23-13(5)24-20)25(11-22-18)17-9-8-14(12(3)4)10-16(17)21/h8-12,15H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074522 (CHEMBL354940 | [9-(2-Bromo-4,6-dimethoxy-phenyl)-2...) Show SMILES CCCCN(CC)c1nc(C)nc2n(cnc12)-c1c(Br)cc(OC)cc1OC |(15.36,-2.57,;14.02,-1.8,;12.68,-2.57,;11.35,-1.8,;10.02,-2.57,;8.68,-1.8,;8.68,-.24,;10.02,-4.11,;8.68,-4.88,;8.68,-6.42,;7.33,-7.19,;10.02,-7.19,;11.35,-6.42,;12.81,-6.89,;13.7,-5.63,;12.81,-4.39,;11.35,-4.88,;13.14,-8.38,;14.59,-8.87,;15.73,-7.82,;14.92,-10.37,;13.79,-11.39,;14.12,-12.91,;13,-13.96,;12.32,-10.93,;11.99,-9.43,;10.52,-8.96,;9.38,-9.99,)| Show InChI InChI=1S/C20H26BrN5O2/c1-6-8-9-25(7-2)19-17-20(24-13(3)23-19)26(12-22-17)18-15(21)10-14(27-4)11-16(18)28-5/h10-12H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074546 (CHEMBL169430 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...) Show SMILES CCCC(CCC)Nc1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H30BrN5/c1-6-8-17(9-7-2)27-21-20-22(26-15(5)25-21)28(13-24-20)19-11-10-16(14(3)4)12-18(19)23/h10-14,17H,6-9H2,1-5H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074456 (CHEMBL10504 | SC241 | [3-(2-Bromo-4-isopropyl-phen...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H27BrN6O2/c1-13(2)15-6-7-17(16(21)12-15)27-20-18(24-25-27)19(22-14(3)23-20)26(8-10-28-4)9-11-29-5/h6-7,12-13H,8-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM84745 (CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 |r| Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of rat NET				Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074495 (CHEMBL355049 | [3-(2-Bromo-4-isopropyl-phenyl)-2,5...) Show SMILES CCCCN(CC)c1cc(C)nc2n(c(C)nc12)-c1ccc(cc1Br)C(C)C |(12.66,1.93,;12.66,.37,;11.33,-.4,;11.33,-1.94,;10,-2.71,;8.67,-1.94,;7.32,-2.71,;10,-4.25,;8.67,-5.02,;8.67,-6.55,;7.32,-7.34,;10,-7.32,;11.33,-6.55,;12.79,-7.02,;13.68,-5.79,;15.22,-5.8,;12.79,-4.54,;11.33,-5.02,;13.42,-8.43,;12.51,-9.68,;13.14,-11.09,;14.66,-11.25,;15.57,-10,;14.94,-8.6,;15.85,-7.35,;15.29,-12.67,;16.82,-12.85,;14.38,-13.92,)| Show InChI InChI=1S/C23H31BrN4/c1-7-9-12-27(8-2)21-13-16(5)25-23-22(21)26-17(6)28(23)20-11-10-18(15(3)4)14-19(20)24/h10-11,13-15H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074525 (CHEMBL355689 | [5-Methyl-3-(2,4,6-trimethyl-phenyl...) Show SMILES CCCC(CCC)Nc1nc(C)nc2n(nnc12)-c1c(C)cc(C)cc1C |(7.49,-7.24,;8.82,-6.47,;8.82,-4.93,;10.15,-4.16,;10.15,-2.61,;8.82,-1.84,;8.82,-.29,;11.49,-4.93,;11.49,-6.47,;10.15,-7.24,;10.15,-8.78,;8.8,-9.55,;11.49,-9.55,;12.82,-8.78,;14.28,-9.25,;15.17,-8,;14.28,-6.77,;12.82,-7.24,;14.61,-10.76,;16.06,-11.23,;17.2,-10.2,;16.39,-12.72,;15.26,-13.77,;15.59,-15.27,;13.79,-13.28,;13.46,-11.79,;11.99,-11.32,)| Show InChI InChI=1S/C21H30N6/c1-7-9-17(10-8-2)24-20-18-21(23-16(6)22-20)27(26-25-18)19-14(4)11-13(3)12-15(19)5/h11-12,17H,7-10H2,1-6H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074404 (CHEMBL168844 | N-(2-Bromo-4-isopropyl-phenyl)-N-et...) Show SMILES CCCN(CCC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H32BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h10-11,14-15H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074391 (CHEMBL424555 | N,N-Diallyl-N'-(2-bromo-4-isopropyl...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h7-8,10-11,14-15H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074332 (CHEMBL167463 | N,N-Diallyl-N'-(2-bromo-4-trifluoro...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(OC(F)(F)F)cc1Br Show InChI InChI=1S/C19H21BrF3N5O/c1-5-10-27(11-6-2)17-24-13(4)25-18(26-17)28(7-3)16-9-8-14(12-15(16)20)29-19(21,22)23/h5-6,8-9,12H,1-2,7,10-11H2,3-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076903 (3-(2-Bromo-4-isopropyl-phenyl)-7-(cyclopropylmethy...) Show SMILES CCCN(CC1CC1)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)sc12 |(16.46,-9.59,;15.12,-10.36,;15.13,-11.91,;13.8,-12.68,;12.46,-11.92,;12.46,-10.39,;13.22,-9.05,;11.69,-9.05,;13.8,-14.21,;12.48,-14.97,;12.48,-16.52,;11.14,-17.3,;13.8,-17.3,;15.15,-16.52,;16.62,-16.98,;17.1,-18.44,;16.08,-19.58,;16.55,-21.04,;18.06,-21.34,;19.08,-20.19,;18.59,-18.75,;19.67,-17.65,;18.54,-22.81,;17.52,-23.95,;20.06,-23.12,;17.52,-15.74,;19.05,-15.74,;16.6,-14.5,;15.13,-14.97,)| Show InChI InChI=1S/C22H27BrN4OS/c1-5-10-26(12-15-6-7-15)20-19-21(25-14(4)24-20)27(22(28)29-19)18-9-8-16(13(2)3)11-17(18)23/h8-9,11,13,15H,5-7,10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076905 (3-(2-Bromo-4-isopropyl-phenyl)-7-diethylamino-5-me...) Show SMILES CCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=S)sc12 |(12.56,-9.82,;12.57,-11.35,;13.88,-12.12,;15.23,-11.35,;15.23,-9.8,;13.91,-13.66,;12.57,-14.45,;12.57,-15.97,;11.25,-16.74,;13.91,-16.74,;15.25,-15.97,;16.7,-16.44,;17.18,-17.89,;16.16,-19.04,;16.64,-20.51,;18.17,-20.8,;19.19,-19.65,;18.69,-18.2,;19.78,-17.11,;18.65,-22.27,;17.62,-23.42,;20.15,-22.59,;17.62,-15.19,;19.16,-15.19,;16.7,-13.95,;15.23,-14.43,)| Show InChI InChI=1S/C19H23BrN4S2/c1-6-23(7-2)17-16-18(22-12(5)21-17)24(19(25)26-16)15-9-8-13(11(3)4)10-14(15)20/h8-11H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074472 (CHEMBL352340 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...) Show SMILES CCCCN(CC)c1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-6-8-11-26(7-2)20-19-21(25-15(5)24-20)27(13-23-19)18-10-9-16(14(3)4)12-17(18)22/h9-10,12-14H,6-8,11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074520 (Allyl-[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-...) Show SMILES COCCN(CC=C)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H25BrN6O/c1-6-9-26(10-11-28-5)19-18-20(23-14(4)22-19)27(25-24-18)17-8-7-15(13(2)3)12-16(17)21/h6-8,12-13H,1,9-11H2,2-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074534 (CHEMBL367110 | [9-(2-Bromo-4-isopropyl-phenyl)-2-m...) Show SMILES CCCC(CC)Nc1nc(C)nc2n(cnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-6-8-16(7-2)26-20-19-21(25-14(5)24-20)27(12-23-19)18-10-9-15(13(3)4)11-17(18)22/h9-13,16H,6-8H2,1-5H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074447 (Butyl-[3-(2-chloro-4,6-dimethoxy-phenyl)-5-methyl-...) Show SMILES CCCCN(CC)c1nc(C)nc2n(nnc12)-c1c(Cl)cc(OC)cc1OC |(15.38,-2.71,;14.03,-1.94,;12.71,-2.71,;11.37,-1.94,;10.04,-2.71,;8.7,-1.94,;8.7,-.4,;10.04,-4.25,;8.7,-5.02,;8.7,-6.55,;7.36,-7.32,;10.04,-7.32,;11.37,-6.55,;12.82,-7.04,;13.73,-5.79,;12.82,-4.55,;11.37,-5.02,;13.15,-8.54,;14.62,-9,;15.76,-7.98,;14.94,-10.51,;13.8,-11.54,;14.15,-13.05,;13.01,-14.1,;12.33,-11.07,;12.01,-9.56,;10.54,-9.09,;9.4,-10.13,)| Show InChI InChI=1S/C19H25ClN6O2/c1-6-8-9-25(7-2)18-16-19(22-12(3)21-18)26(24-23-16)17-14(20)10-13(27-4)11-15(17)28-5/h10-11H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076609 (6-(Butyl-ethyl-amino)-2,7-dimethyl-9-(2,4,6-trimet...) Show SMILES CCCCN(CC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=O)n(C)c12 |(5.81,1.7,;5.81,.16,;4.48,-.61,;4.5,-2.15,;5.84,-2.91,;7.18,-2.14,;7.17,-.61,;5.85,-4.45,;4.52,-5.22,;4.52,-6.77,;3.18,-7.54,;5.85,-7.54,;7.19,-6.76,;8.66,-7.23,;9.15,-8.68,;10.64,-8.98,;11.66,-7.82,;11.13,-10.44,;10.1,-11.59,;10.59,-13.06,;8.6,-11.29,;8.12,-9.82,;6.61,-9.51,;9.57,-5.98,;11.11,-5.97,;8.65,-4.73,;9.12,-3.27,;7.19,-5.22,)| Show InChI InChI=1S/C22H31N5O/c1-8-10-11-26(9-2)20-19-21(24-17(6)23-20)27(22(28)25(19)7)18-15(4)12-14(3)13-16(18)5/h12-13H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...				Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50401743 (CHEMBL2206526) Show SMILES CN1CC(c2ccc(C)c(F)c2)c2ccccc2C1 Show InChI InChI=1S/C17H18FN/c1-12-7-8-13(9-17(12)18)16-11-19(2)10-14-5-3-4-6-15(14)16/h3-9,16H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human NET				Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074454 (CHEMBL169781 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES CCCCC(CCCC)Nc1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C23H33BrN6/c1-6-8-10-18(11-9-7-2)27-22-21-23(26-16(5)25-22)30(29-28-21)20-13-12-17(15(3)4)14-19(20)24/h12-15,18H,6-11H2,1-5H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074457 (CHEMBL355329 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES COCCN(CC1CC1)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H27BrN6O/c1-13(2)16-7-8-18(17(22)11-16)28-21-19(25-26-28)20(23-14(3)24-21)27(9-10-29-4)12-15-5-6-15/h7-8,11,13,15H,5-6,9-10,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074449 (CHEMBL352353 | [3-(4-Isopropyl-2-methylsulfanyl-ph...) Show SMILES COCCN(CCOC)c1cc(C)nc2n(nnc12)-c1ccc(cc1SC)C(C)C Show InChI InChI=1S/C22H31N5O2S/c1-15(2)17-7-8-18(20(14-17)30-6)27-22-21(24-25-27)19(13-16(3)23-22)26(9-11-28-4)10-12-29-5/h7-8,13-15H,9-12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074503 (CHEMBL169561 | [3-(2-Bromo-4-isopropyl-phenyl)-5-m...) Show SMILES COCCN(CCOC)c1cc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5O2/c1-14(2)16-6-7-18(17(22)13-16)27-21-20(24-25-27)19(12-15(3)23-21)26(8-10-28-4)9-11-29-5/h6-7,12-14H,8-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50401732 (CHEMBL2206507) Show SMILES CN1CC(c2cccc(Cl)c2)c2ccc(C)cc2C1 Show InChI InChI=1S/C17H18ClN/c1-12-6-7-16-14(8-12)10-19(2)11-17(16)13-4-3-5-15(18)9-13/h3-9,17H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human NET				Bioorg Med Chem Lett 22: 7219-22 (2012) Article DOI: 10.1016/j.bmcl.2012.09.050 BindingDB Entry DOI: 10.7270/Q20K29QC
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076902 (7-[Bis-(2-methoxy-ethyl)-amino]-5-methyl-3-(2,4,6-...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=O)sc12 |(18.84,-10.28,;17.3,-10.28,;15.96,-11.05,;15.96,-12.59,;14.63,-13.38,;13.29,-12.61,;13.29,-11.07,;12.51,-9.75,;10.97,-9.73,;14.64,-14.92,;13.31,-15.69,;13.31,-17.23,;11.97,-18,;14.64,-18,;15.99,-17.23,;17.45,-17.69,;17.93,-19.15,;19.44,-19.45,;20.45,-18.3,;19.92,-20.9,;18.9,-22.07,;19.39,-23.53,;17.39,-21.76,;16.91,-20.29,;15.4,-19.97,;18.36,-16.44,;19.9,-16.44,;17.43,-15.19,;15.98,-15.69,)| Show InChI InChI=1S/C21H28N4O3S/c1-13-11-14(2)17(15(3)12-13)25-20-18(29-21(25)26)19(22-16(4)23-20)24(7-9-27-5)8-10-28-6/h11-12H,7-10H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity against human Corticotropin releasing factor receptor 1 expressed in HEK 293E cells using [125I]-TYR-oCRH				Bioorg Med Chem Lett 9: 1185-8 (1999) BindingDB Entry DOI: 10.7270/Q24M93Q4
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076619 (9-(2-Bromo-4-isopropyl-phenyl)-6-(butyl-ethyl-amin...) Show SMILES CCCCN(CC)c1nc(C)nc2n(-c3ccc(cc3Br)C(C)C)c(=O)n(C)c12 |(4.5,1.47,;3.17,2.22,;1.83,1.45,;.48,2.21,;-.83,1.44,;-2.18,2.21,;-3.51,1.42,;-.83,-.1,;-2.16,-.86,;-2.16,-2.41,;-3.5,-3.18,;-.83,-3.18,;.51,-2.41,;1.98,-2.86,;2.47,-4.33,;1.44,-5.45,;1.95,-6.94,;3.46,-7.22,;4.48,-6.07,;3.98,-4.61,;5,-3.46,;3.94,-8.7,;2.95,-9.85,;5.45,-8.99,;2.88,-1.61,;4.42,-1.59,;1.96,-.38,;2.71,.96,;.5,-.86,)| Show InChI InChI=1S/C22H30BrN5O/c1-7-9-12-27(8-2)20-19-21(25-15(5)24-20)28(22(29)26(19)6)18-11-10-16(14(3)4)13-17(18)23/h10-11,13-14H,7-9,12H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for transfected human Corticotropin releasing factor receptor expressed in HEK 293E cells using [125I]-TYR-oCRH as the displaced rad...				Bioorg Med Chem Lett 9: 967-72 (1999) BindingDB Entry DOI: 10.7270/Q26H4GKK
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074490 (Benzyl-[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H...) Show SMILES COCCN(Cc1ccccc1)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C24H27BrN6O/c1-16(2)19-10-11-21(20(25)14-19)31-24-22(28-29-31)23(26-17(3)27-24)30(12-13-32-4)15-18-8-6-5-7-9-18/h5-11,14,16H,12-13,15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity to recombinant human Corticotropin releasing factor receptor 1 (hCRF1) expressed in 293EBNA cells				J Med Chem 42: 833-48 (1999) Article DOI: 10.1021/jm980224g BindingDB Entry DOI: 10.7270/Q2610ZGP
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074401 (CHEMBL166345 | N-Allyl-N'-(2-bromo-4-isopropyl-phe...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)C1CC1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-6-12-27(17-9-10-17)21-24-15(5)23-20(25-21)26(7-2)19-11-8-16(14(3)4)13-18(19)22/h6,8,11,13-14,17H,1,7,9-10,12H2,2-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074399 (CHEMBL354367 | N-(2-Bromo-4-trifluoromethoxy-pheny...) Show SMILES CCCCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(OC(F)(F)F)cc1Br Show InChI InChI=1S/C19H25BrF3N5O/c1-5-8-11-27(6-2)17-24-13(4)25-18(26-17)28(7-3)16-10-9-14(12-15(16)20)29-19(21,22)23/h9-10,12H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074333 (CHEMBL353877 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...) Show SMILES CCCN(C1CC1)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H31BrN4/c1-6-12-27(18-9-10-18)21-13-16(5)24-22(25-21)26(7-2)20-11-8-17(15(3)4)14-19(20)23/h8,11,13-15,18H,6-7,9-10,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074330 (3-({4-[(4-Dimethylamino-2-trifluoromethyl-phenyl)-...) Show SMILES CCCN(CCC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C21H28F3N7/c1-6-12-30(13-8-11-25)19-26-15(3)27-20(28-19)31(7-2)18-10-9-16(29(4)5)14-17(18)21(22,23)24/h9-10,14H,6-8,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1645 total )  |  Next  |  Last  >>

Jump to: