Found 1281 hits with Last Name = 'meng' and Initial = 'q' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090516
![PNG](/data/jpeg/tenK5009/BindingDB_50090516.png) (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...)Show InChI InChI=1S/C18H26N2/c1-18(2,3)14-7-8-17-16(11-14)13(12-19-17)10-15-6-5-9-20(15)4/h7-8,11-12,15,19H,5-6,9-10H2,1-4H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090517
![PNG](/data/jpeg/tenK5009/BindingDB_50090517.png) (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)Show InChI InChI=1S/C17H24N2/c1-12(2)13-6-7-17-16(10-13)14(11-18-17)9-15-5-4-8-19(15)3/h6-7,10-12,15,18H,4-5,8-9H2,1-3H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090519
![PNG](/data/jpeg/tenK5009/BindingDB_50090519.png) (CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...)Show InChI InChI=1S/C15H22N2/c1-11(2)12-5-6-15-14(9-12)13(10-16-15)7-8-17(3)4/h5-6,9-11,16H,7-8H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090523
![PNG](/data/jpeg/tenK5009/BindingDB_50090523.png) (2-(5-tert-Butyl-1-methyl-1H-indol-3-yl)-ethylamine...)Show InChI InChI=1S/C15H22N2/c1-15(2,3)12-5-6-14-13(9-12)11(7-8-16)10-17(14)4/h5-6,9-10H,7-8,16H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088870
![PNG](/data/jpeg/tenK5008/BindingDB_50088870.png) (CHEMBL171129 | Dimethyl-[2-(5-thiophen-3-yl-1H-ind...)Show InChI InChI=1S/C16H18N2S/c1-18(2)7-5-13-10-17-16-4-3-12(9-15(13)16)14-6-8-19-11-14/h3-4,6,8-11,17H,5,7H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088867
![PNG](/data/jpeg/tenK5008/BindingDB_50088867.png) (CHEMBL170192 | Dimethyl-[2-(5-thiophen-2-yl-1H-ind...)Show InChI InChI=1S/C16H18N2S/c1-18(2)8-7-13-11-17-15-6-5-12(10-14(13)15)16-4-3-9-19-16/h3-6,9-11,17H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090522
![PNG](/data/jpeg/tenK5009/BindingDB_50090522.png) (5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...)Show InChI InChI=1S/C16H22N2/c1-3-12-6-7-16-15(9-12)13(11-17-16)10-14-5-4-8-18(14)2/h6-7,9,11,14,17H,3-5,8,10H2,1-2H3/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088863
![PNG](/data/jpeg/tenK5008/BindingDB_50088863.png) (2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine | CHE...)Show InChI InChI=1S/C14H14N2S/c15-6-5-11-9-16-13-4-3-10(8-12(11)13)14-2-1-7-17-14/h1-4,7-9,16H,5-6,15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088864
![PNG](/data/jpeg/tenK5008/BindingDB_50088864.png) (3-[2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-ethyl]-...)Show SMILES COC[C@@H]1CCCN1CCc1c[nH]c2ccc(cc12)-c1cccs1 Show InChI InChI=1S/C20H24N2OS/c1-23-14-17-4-2-9-22(17)10-8-16-13-21-19-7-6-15(12-18(16)19)20-5-3-11-24-20/h3,5-7,11-13,17,21H,2,4,8-10,14H2,1H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090521
![PNG](/data/jpeg/tenK5009/BindingDB_50090521.png) (5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...)Show InChI InChI=1S/C18H26N2/c1-18(2,3)15-6-7-17-16(12-15)14(13-19-17)8-11-20-9-4-5-10-20/h6-7,12-13,19H,4-5,8-11H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088869
![PNG](/data/jpeg/tenK5008/BindingDB_50088869.png) (3-[2-(2,5-Dimethyl-pyrrolidin-1-yl)-ethyl]-5-thiop...)Show InChI InChI=1S/C20H24N2S/c1-14-5-6-15(2)22(14)10-9-17-13-21-19-8-7-16(12-18(17)19)20-4-3-11-23-20/h3-4,7-8,11-15,21H,5-6,9-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088866
![PNG](/data/jpeg/tenK5008/BindingDB_50088866.png) (CHEMBL174355 | Dimethyl-{2-[5-(5-methyl-thiophen-2...)Show InChI InChI=1S/C17H20N2S/c1-12-4-7-17(20-12)13-5-6-16-15(10-13)14(11-18-16)8-9-19(2)3/h4-7,10-11,18H,8-9H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090515
![PNG](/data/jpeg/tenK5009/BindingDB_50090515.png) (5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...)Show InChI InChI=1S/C15H20N2/c1-11-5-6-15-14(8-11)12(10-16-15)9-13-4-3-7-17(13)2/h5-6,8,10,13,16H,3-4,7,9H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088868
![PNG](/data/jpeg/tenK5008/BindingDB_50088868.png) (3-[2-(2,5-Dihydro-pyrrol-1-yl)-ethyl]-5-thiophen-2...)Show SMILES C(Cc1c[nH]c2ccc(cc12)-c1cccs1)N1CC=CC1 |c:21| Show InChI InChI=1S/C18H18N2S/c1-2-9-20(8-1)10-7-15-13-19-17-6-5-14(12-16(15)17)18-4-3-11-21-18/h1-6,11-13,19H,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090518
![PNG](/data/jpeg/tenK5009/BindingDB_50090518.png) (5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...)Show InChI InChI=1S/C17H24N2/c1-13(2)14-5-6-17-16(11-14)15(12-18-17)7-10-19-8-3-4-9-19/h5-6,11-13,18H,3-4,7-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50005835
![PNG](/data/jpeg/tenK5000/BindingDB_50005835.png) ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
| DrugBank PubMed
| 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088860
![PNG](/data/jpeg/tenK5008/BindingDB_50088860.png) (CHEMBL422737 | {2-[5-(5-Chloro-thiophen-2-yl)-1H-i...)Show InChI InChI=1S/C16H17ClN2S/c1-19(2)8-7-12-10-18-14-4-3-11(9-13(12)14)15-5-6-16(17)20-15/h3-6,9-10,18H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088865
![PNG](/data/jpeg/tenK5008/BindingDB_50088865.png) (CHEMBL174141 | {(S)-1-[2-(5-Thiophen-2-yl-1H-indol...)Show InChI InChI=1S/C19H22N2OS/c22-13-16-3-1-8-21(16)9-7-15-12-20-18-6-5-14(11-17(15)18)19-4-2-10-23-19/h2,4-6,10-12,16,20,22H,1,3,7-9,13H2/t16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088864
![PNG](/data/jpeg/tenK5008/BindingDB_50088864.png) (3-[2-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-ethyl]-...)Show SMILES COC[C@@H]1CCCN1CCc1c[nH]c2ccc(cc12)-c1cccs1 Show InChI InChI=1S/C20H24N2OS/c1-23-14-17-4-2-9-22(17)10-8-16-13-21-19-7-6-15(12-18(16)19)20-5-3-11-24-20/h3,5-7,11-13,17,21H,2,4,8-10,14H2,1H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090517
![PNG](/data/jpeg/tenK5009/BindingDB_50090517.png) (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...)Show InChI InChI=1S/C17H24N2/c1-12(2)13-6-7-17-16(10-13)14(11-18-17)9-15-5-4-8-19(15)3/h6-7,10-12,15,18H,4-5,8-9H2,1-3H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50005835
![PNG](/data/jpeg/tenK5000/BindingDB_50005835.png) ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
| DrugBank PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090519
![PNG](/data/jpeg/tenK5009/BindingDB_50090519.png) (CHEMBL300519 | [2-(5-Isopropyl-1H-indol-3-yl)-ethy...)Show InChI InChI=1S/C15H22N2/c1-11(2)12-5-6-15-14(9-12)13(10-16-15)7-8-17(3)4/h5-6,9-11,16H,7-8H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50049099
![PNG](/data/jpeg/tenK5004/BindingDB_50049099.png) (CHEMBL50492 | [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...)Show InChI InChI=1S/C14H20N2/c1-4-11-5-6-14-13(9-11)12(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090516
![PNG](/data/jpeg/tenK5009/BindingDB_50090516.png) (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...)Show InChI InChI=1S/C18H26N2/c1-18(2,3)14-7-8-17-16(11-14)13(12-19-17)10-15-6-5-9-20(15)4/h7-8,11-12,15,19H,5-6,9-10H2,1-4H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088870
![PNG](/data/jpeg/tenK5008/BindingDB_50088870.png) (CHEMBL171129 | Dimethyl-[2-(5-thiophen-3-yl-1H-ind...)Show InChI InChI=1S/C16H18N2S/c1-18(2)7-5-13-10-17-16-4-3-12(9-15(13)16)14-6-8-19-11-14/h3-4,6,8-11,17H,5,7H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088861
![PNG](/data/jpeg/tenK5008/BindingDB_50088861.png) (3-(2-Pyrrolidin-1-yl-ethyl)-5-thiophen-2-yl-1H-ind...)Show InChI InChI=1S/C18H20N2S/c1-2-9-20(8-1)10-7-15-13-19-17-6-5-14(12-16(15)17)18-4-3-11-21-18/h3-6,11-13,19H,1-2,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088867
![PNG](/data/jpeg/tenK5008/BindingDB_50088867.png) (CHEMBL170192 | Dimethyl-[2-(5-thiophen-2-yl-1H-ind...)Show InChI InChI=1S/C16H18N2S/c1-18(2)8-7-13-11-17-15-6-5-12(10-14(13)15)16-4-3-9-19-16/h3-6,9-11,17H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50088862
![PNG](/data/jpeg/tenK5008/BindingDB_50088862.png) (5-(5-Chloro-thiophen-2-yl)-3-(2-pyrrolidin-1-yl-et...)Show InChI InChI=1S/C18H19ClN2S/c19-18-6-5-17(22-18)13-3-4-16-15(11-13)14(12-20-16)7-10-21-8-1-2-9-21/h3-6,11-12,20H,1-2,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088863
![PNG](/data/jpeg/tenK5008/BindingDB_50088863.png) (2-(5-Thiophen-2-yl-1H-indol-3-yl)-ethylamine | CHE...)Show InChI InChI=1S/C14H14N2S/c15-6-5-11-9-16-13-4-3-10(8-12(11)13)14-2-1-7-17-14/h1-4,7-9,16H,5-6,15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50005835
![PNG](/data/jpeg/tenK5000/BindingDB_50005835.png) ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
| DrugBank PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50090520
![PNG](/data/jpeg/tenK5009/BindingDB_50090520.png) (5-Ethyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CH...)Show InChI InChI=1S/C16H22N2/c1-2-13-5-6-16-15(11-13)14(12-17-16)7-10-18-8-3-4-9-18/h5-6,11-12,17H,2-4,7-10H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090522
![PNG](/data/jpeg/tenK5009/BindingDB_50090522.png) (5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...)Show InChI InChI=1S/C16H22N2/c1-3-12-6-7-16-15(9-12)13(11-17-16)10-14-5-4-8-18(14)2/h6-7,9,11,14,17H,3-5,8,10H2,1-2H3/t14-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 47 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50005835
![PNG](/data/jpeg/tenK5000/BindingDB_50005835.png) ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...)Show InChI InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
| DrugBank PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088869
![PNG](/data/jpeg/tenK5008/BindingDB_50088869.png) (3-[2-(2,5-Dimethyl-pyrrolidin-1-yl)-ethyl]-5-thiop...)Show InChI InChI=1S/C20H24N2S/c1-14-5-6-15(2)22(14)10-9-17-13-21-19-8-7-16(12-18(17)19)20-4-3-11-23-20/h3-4,7-8,11-15,21H,5-6,9-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088868
![PNG](/data/jpeg/tenK5008/BindingDB_50088868.png) (3-[2-(2,5-Dihydro-pyrrol-1-yl)-ethyl]-5-thiophen-2...)Show SMILES C(Cc1c[nH]c2ccc(cc12)-c1cccs1)N1CC=CC1 |c:21| Show InChI InChI=1S/C18H18N2S/c1-2-9-20(8-1)10-7-15-13-19-17-6-5-14(12-16(15)17)18-4-3-11-21-18/h1-6,11-13,19H,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088865
![PNG](/data/jpeg/tenK5008/BindingDB_50088865.png) (CHEMBL174141 | {(S)-1-[2-(5-Thiophen-2-yl-1H-indol...)Show InChI InChI=1S/C19H22N2OS/c22-13-16-3-1-8-21(16)9-7-15-12-20-18-6-5-14(11-17(15)18)19-4-2-10-23-19/h2,4-6,10-12,16,20,22H,1,3,7-9,13H2/t16-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090515
![PNG](/data/jpeg/tenK5009/BindingDB_50090515.png) (5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...)Show InChI InChI=1S/C15H20N2/c1-11-5-6-15-14(8-11)12(10-16-15)9-13-4-3-7-17(13)2/h5-6,8,10,13,16H,3-4,7,9H2,1-2H3/t13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 118 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088866
![PNG](/data/jpeg/tenK5008/BindingDB_50088866.png) (CHEMBL174355 | Dimethyl-{2-[5-(5-methyl-thiophen-2...)Show InChI InChI=1S/C17H20N2S/c1-12-4-7-17(20-12)13-5-6-16-15(10-13)14(11-18-16)8-9-19(2)3/h4-7,10-11,18H,8-9H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50049099
![PNG](/data/jpeg/tenK5004/BindingDB_50049099.png) (CHEMBL50492 | [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...)Show InChI InChI=1S/C14H20N2/c1-4-11-5-6-14-13(9-11)12(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 286 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088860
![PNG](/data/jpeg/tenK5008/BindingDB_50088860.png) (CHEMBL422737 | {2-[5-(5-Chloro-thiophen-2-yl)-1H-i...)Show InChI InChI=1S/C16H17ClN2S/c1-19(2)8-7-12-10-18-14-4-3-11(9-13(12)14)15-5-6-16(17)20-15/h3-6,9-10,18H,7-8H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 303 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090521
![PNG](/data/jpeg/tenK5009/BindingDB_50090521.png) (5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...)Show InChI InChI=1S/C18H26N2/c1-18(2,3)15-6-7-17-16(12-15)14(13-19-17)8-11-20-9-4-5-10-20/h6-7,12-13,19H,4-5,8-11H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 312 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090518
![PNG](/data/jpeg/tenK5009/BindingDB_50090518.png) (5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...)Show InChI InChI=1S/C17H24N2/c1-13(2)14-5-6-17-16(11-14)15(12-18-17)7-10-19-8-3-4-9-19/h5-6,11-13,18H,3-4,7-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 472 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088862
![PNG](/data/jpeg/tenK5008/BindingDB_50088862.png) (5-(5-Chloro-thiophen-2-yl)-3-(2-pyrrolidin-1-yl-et...)Show InChI InChI=1S/C18H19ClN2S/c19-18-6-5-17(22-18)13-3-4-16-15(11-13)14(12-20-16)7-10-21-8-1-2-9-21/h3-6,11-12,20H,1-2,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 476 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50088861
![PNG](/data/jpeg/tenK5008/BindingDB_50088861.png) (3-(2-Pyrrolidin-1-yl-ethyl)-5-thiophen-2-yl-1H-ind...)Show InChI InChI=1S/C18H20N2S/c1-2-9-20(8-1)10-7-15-13-19-17-6-5-14(12-16(15)17)18-4-3-11-21-18/h3-6,11-13,19H,1-2,7-10H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 714 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 903-5 (2000)
BindingDB Entry DOI: 10.7270/Q24F1PZJ |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human)) | BDBM50088500
![PNG](/data/jpeg/tenK5008/BindingDB_50088500.png) (CHEBI:74023 | Dioscin)Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O |r,t:8| Show InChI InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University
Curated by ChEMBL
| Assay Description Cellular uptake in HEK293 cells expressing OATP1B3 (unknown origin) assessed as inhibition of telmisartan-mediated drug transport |
Drug Metab Dispos 41: 994-1003 (2013)
Article DOI: 10.1124/dmd.112.049452 BindingDB Entry DOI: 10.7270/Q2D220B8 |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human)) | BDBM50088500
![PNG](/data/jpeg/tenK5008/BindingDB_50088500.png) (CHEBI:74023 | Dioscin)Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O |r,t:8| Show InChI InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University
Curated by ChEMBL
| Assay Description Cellular uptake in HEK293 cells expressing OATP1B3 (unknown origin) assessed as inhibition of cyclosporin A-mediated drug transport |
Drug Metab Dispos 41: 994-1003 (2013)
Article DOI: 10.1124/dmd.112.049452 BindingDB Entry DOI: 10.7270/Q2D220B8 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50090520
![PNG](/data/jpeg/tenK5009/BindingDB_50090520.png) (5-Ethyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole | CH...)Show InChI InChI=1S/C16H22N2/c1-2-13-5-6-16-15(11-13)14(12-17-16)7-10-18-8-3-4-9-18/h5-6,11-12,17H,2-4,7-10H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Allelix Corp.
Curated by ChEMBL
| Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor |
Bioorg Med Chem Lett 10: 1707-9 (2000)
BindingDB Entry DOI: 10.7270/Q2GF0SRT |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human)) | BDBM50088500
![PNG](/data/jpeg/tenK5008/BindingDB_50088500.png) (CHEBI:74023 | Dioscin)Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O |r,t:8| Show InChI InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 4.55E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University
Curated by ChEMBL
| Assay Description Cellular uptake in HEK293 cells expressing OATP1B3 (unknown origin) assessed as inhibition of rifampicin-mediated drug transport |
Drug Metab Dispos 41: 994-1003 (2013)
Article DOI: 10.1124/dmd.112.049452 BindingDB Entry DOI: 10.7270/Q2D220B8 |
More data for this Ligand-Target Pair | |
Solute carrier organic anion transporter family member 1B3
(Homo sapiens (Human)) | BDBM50088500
![PNG](/data/jpeg/tenK5008/BindingDB_50088500.png) (CHEBI:74023 | Dioscin)Show SMILES [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@@H](O[C@]2([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O |r,t:8| Show InChI InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 8.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian Medical University
Curated by ChEMBL
| Assay Description Cellular uptake in HEK293 cells expressing OATP1B3 (unknown origin) assessed as inhibition of (-)-epigallocatechin gallate-mediated drug transport |
Drug Metab Dispos 41: 994-1003 (2013)
Article DOI: 10.1124/dmd.112.049452 BindingDB Entry DOI: 10.7270/Q2D220B8 |
More data for this Ligand-Target Pair | |
Neutrophil elastase
(Homo sapiens (Human)) | BDBM50583309
![PNG](/data/jpeg/tenK5058/BindingDB_50583309.png) (CHEMBL4204851)Show SMILES [Na;v0+].[#6]-[#6]-[#6]-[#6@@H]-1-[#7]-[#6](=O)-[#6@H](-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]S([#8-])(=O)=O)-[#7]-[#6](=O)\[#6]=[#6]\c2csc(n2)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6](=O)-[#6@@H](-[#7]-[#6]-1=O)-[#6@@H](-[#6])-[#6]-[#6])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1ccc(-[#8])cc1 |r,t:21| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.0340 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human neutrophil elastase |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01583 BindingDB Entry DOI: 10.7270/Q2R78K38 |
More data for this Ligand-Target Pair | |