Compile Data Set for Download or QSAR

Found 133 hits with Last Name = 'chippari' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50257270 (CHEMBL4088158) Show SMILES Cn1c(ccc1-c1ccc(O)cc1Cl)C#N Show InChI InChI=1S/C12H9ClN2O/c1-15-8(7-14)2-5-12(15)10-4-3-9(16)6-11(10)13/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257265 (CHEMBL4095364) Show SMILES Cn1c(ccc1-c1c(F)cc(O)cc1F)C#N |(9.8,-30.9,;9.75,-29.36,;8.48,-28.5,;8.91,-27.02,;10.45,-26.97,;10.97,-28.42,;12.44,-28.84,;13.55,-27.78,;13.18,-26.29,;15.03,-28.2,;15.4,-29.71,;16.88,-30.13,;14.29,-30.77,;12.81,-30.34,;11.7,-31.41,;7.02,-29.02,;5.57,-29.54,)| Show InChI InChI=1S/C12H8F2N2O/c1-16-7(6-15)2-3-11(16)12-9(13)4-8(17)5-10(12)14/h2-5,17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257275 (CHEMBL4065842) Show SMILES Cc1cc(ccc1O)-c1ccc(C#N)n1C Show InChI InChI=1S/C13H12N2O/c1-9-7-10(3-6-13(9)16)12-5-4-11(8-14)15(12)2/h3-7,16H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157485 (4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl...) Show SMILES CC(C)n1nc(-c2ccc(O)cc2)c2cccc(c12)C(F)(F)F Show InChI InChI=1S/C17H15F3N2O/c1-10(2)22-16-13(4-3-5-14(16)17(18,19)20)15(21-22)11-6-8-12(23)9-7-11/h3-10,23H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257272 (CHEMBL4095883) Show SMILES Cn1c(ccc1-c1ccc(O)cc1F)C#N Show InChI InChI=1S/C12H9FN2O/c1-15-8(7-14)2-5-12(15)10-4-3-9(16)6-11(10)13/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50257274 (CHEMBL4079377) Show SMILES Cc1cc(O)ccc1-c1ccc(C#N)n1C Show InChI InChI=1S/C13H12N2O/c1-9-7-11(16)4-5-12(9)13-6-3-10(8-14)15(13)2/h3-7,16H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257284 (CHEMBL4072730) Show SMILES Cc1c(O)ccc(-c2ccc(C#N)n2C)c1C Show InChI InChI=1S/C14H14N2O/c1-9-10(2)14(17)7-5-12(9)13-6-4-11(8-15)16(13)3/h4-7,17H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257276 (CHEMBL4087256) Show SMILES Cn1c(ccc1-c1ccc(O)cc1)C#N Show InChI InChI=1S/C12H10N2O/c1-14-10(8-13)4-7-12(14)9-2-5-11(15)6-3-9/h2-7,15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257315 (CHEMBL4066319) Show SMILES Cn1c(ccc1-c1ccc(O)cc1C#N)C#N Show InChI InChI=1S/C13H9N3O/c1-16-10(8-15)2-5-13(16)12-4-3-11(17)6-9(12)7-14/h2-6,17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257314 (CHEMBL4103641) Show SMILES CCc1cc(ccc1O)-c1ccc(C#N)n1C Show InChI InChI=1S/C14H14N2O/c1-3-10-8-11(4-7-14(10)17)13-6-5-12(9-15)16(13)2/h4-8,17H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257313 (CHEMBL4061510) Show SMILES Cn1c(ccc1-c1ccc(O)c2CCCc12)C#N Show InChI InChI=1S/C15H14N2O/c1-17-10(9-16)5-7-14(17)12-6-8-15(18)13-4-2-3-11(12)13/h5-8,18H,2-4H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257319 (CHEMBL4088572) Show SMILES Cn1c(cc(c1C#N)C(F)(F)F)-c1ccc(O)cc1 Show InChI InChI=1S/C13H9F3N2O/c1-18-11(8-2-4-9(19)5-3-8)6-10(12(18)7-17)13(14,15)16/h2-6,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157496 (4-[1-(2,5-dichlorophenyl)-6-hydroxy-1H-indazol-3-y...) Show SMILES Oc1ccc(-c2nn(-c3cc(Cl)ccc3Cl)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C19H12Cl2N2O3/c20-10-1-6-15(21)17(7-10)23-16-8-11(24)2-4-13(16)19(22-23)14-5-3-12(25)9-18(14)26/h1-9,24-26H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257269 (CHEMBL4073399) Show SMILES Cn1c(ccc1-c1ccc(O)cc1C(F)(F)F)C#N Show InChI InChI=1S/C13H9F3N2O/c1-18-8(7-17)2-5-12(18)10-4-3-9(19)6-11(10)13(14,15)16/h2-6,19H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157488 (4-(7-chloro-1-cyclopentyl-1H-indazol-3-yl)phenol |...) Show SMILES Oc1ccc(cc1)-c1nn(C2CCCC2)c2c(Cl)cccc12 Show InChI InChI=1S/C18H17ClN2O/c19-16-7-3-6-15-17(12-8-10-14(22)11-9-12)20-21(18(15)16)13-4-1-2-5-13/h3,6-11,13,22H,1-2,4-5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157483 (4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenol |...) Show SMILES Oc1ccc(cc1)-c1nn(C2CCCC2)c2c(F)cccc12 Show InChI InChI=1S/C18H17FN2O/c19-16-7-3-6-15-17(12-8-10-14(22)11-9-12)20-21(18(15)16)13-4-1-2-5-13/h3,6-11,13,22H,1-2,4-5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157501 (4-[1-isopropyl-7-(trifluoromethyl)-1H-indazol-3-yl...) Show SMILES CC(C)n1nc(-c2ccc(O)cc2C)c2cccc(c12)C(F)(F)F Show InChI InChI=1S/C18H17F3N2O/c1-10(2)23-17-14(5-4-6-15(17)18(19,20)21)16(22-23)13-8-7-12(24)9-11(13)3/h4-10,24H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157498 (4-(1-butyl-7-chloro-1H-indazol-3-yl)phenol | CHEMB...) Show SMILES CCCCn1nc(-c2ccc(O)cc2)c2cccc(Cl)c12 Show InChI InChI=1S/C17H17ClN2O/c1-2-3-11-20-17-14(5-4-6-15(17)18)16(19-20)12-7-9-13(21)10-8-12/h4-10,21H,2-3,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257278 (CHEMBL4074555) Show SMILES Cn1c(ccc1-c1c(Cl)cc(O)cc1Cl)C#N |(33.03,-30.55,;32.98,-29.01,;31.71,-28.14,;32.14,-26.67,;33.68,-26.61,;34.2,-28.07,;35.68,-28.49,;36.78,-27.43,;36.41,-25.93,;38.26,-27.85,;38.63,-29.35,;40.11,-29.78,;37.52,-30.42,;36.04,-29.99,;34.93,-31.05,;30.25,-28.67,;28.81,-29.19,)| Show InChI InChI=1S/C12H8Cl2N2O/c1-16-7(6-15)2-3-11(16)12-9(13)4-8(17)5-10(12)14/h2-5,17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157491 (4-[1-(2,5-difluorophenyl)-6-hydroxy-1H-indazol-3-y...) Show SMILES Oc1ccc(-c2nn(-c3cc(F)ccc3F)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C19H12F2N2O3/c20-10-1-6-15(21)17(7-10)23-16-8-11(24)2-4-13(16)19(22-23)14-5-3-12(25)9-18(14)26/h1-9,24-26H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157504 (4-(7-chloro-1-cyclohexyl-1H-indazol-3-yl)phenol | ...) Show SMILES Oc1ccc(cc1)-c1nn(C2CCCCC2)c2c(Cl)cccc12 Show InChI InChI=1S/C19H19ClN2O/c20-17-8-4-7-16-18(13-9-11-15(23)12-10-13)21-22(19(16)17)14-5-2-1-3-6-14/h4,7-12,14,23H,1-3,5-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257264 (CHEMBL4069026) Show SMILES Cn1c(ccc1-c1ccc(O)c(F)c1F)C#N Show InChI InChI=1S/C12H8F2N2O/c1-16-7(6-15)2-4-9(16)8-3-5-10(17)12(14)11(8)13/h2-5,17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157489 (4-[1-(3-fluorophenyl)-6-hydroxy-1H-indazol-3-yl]be...) Show SMILES Oc1ccc(-c2nn(-c3cccc(F)c3)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C19H13FN2O3/c20-11-2-1-3-12(8-11)22-17-9-13(23)4-6-15(17)19(21-22)16-7-5-14(24)10-18(16)25/h1-10,23-25H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157500 (4-[6-hydroxy-1-(4-methylphenyl)-1H-indazol-3-yl]be...) Show SMILES Cc1ccc(cc1)-n1nc(-c2ccc(O)cc2O)c2ccc(O)cc12 Show InChI InChI=1S/C20H16N2O3/c1-12-2-4-13(5-3-12)22-18-10-14(23)6-8-16(18)20(21-22)17-9-7-15(24)11-19(17)25/h2-11,23-25H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157503 (4-(7-methyl-1-propyl-1H-indazol-3-yl)phenol | CHEM...) Show SMILES CCCn1nc(-c2ccc(O)cc2)c2cccc(C)c12 Show InChI InChI=1S/C17H18N2O/c1-3-11-19-17-12(2)5-4-6-15(17)16(18-19)13-7-9-14(20)10-8-13/h4-10,20H,3,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257321 (CHEMBL4062016) Show SMILES Cn1c(ccc1-c1ccc(O)c(Cl)c1)C#N Show InChI InChI=1S/C12H9ClN2O/c1-15-9(7-14)3-4-11(15)8-2-5-12(16)10(13)6-8/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157486 (4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL | CH...) Show SMILES Oc1ccc(-c2n[nH]c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C13H10N2O3/c16-7-1-3-9-11(5-7)14-15-13(9)10-4-2-8(17)6-12(10)18/h1-6,16-18H,(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM50157508 (4-[1-(3-chlorophenyl)-6-hydroxy-1H-indazol-3-yl]be...) Show SMILES Oc1ccc(-c2nn(-c3cccc(Cl)c3)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C19H13ClN2O3/c20-11-2-1-3-12(8-11)22-17-9-13(23)4-6-15(17)19(21-22)16-7-5-14(24)10-18(16)25/h1-10,23-25H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157502 (4-(7-chloro-1-propyl-1H-indazol-3-yl)phenol | CHEM...) Show SMILES CCCn1nc(-c2ccc(O)cc2)c2cccc(Cl)c12 Show InChI InChI=1S/C16H15ClN2O/c1-2-10-19-16-13(4-3-5-14(16)17)15(18-19)11-6-8-12(20)9-7-11/h3-9,20H,2,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Cannabinoid receptor 1/2 (Rattus norvegicus (Rat)-Rattus norvegicus (rat))	BDBM50212379 (CHEMBL125462) Show SMILES COc1ccc(\C=C2/C=C(CCN3CCOCC3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C23H25NO2/c1-25-21-8-6-18(7-9-21)16-20-17-19(22-4-2-3-5-23(20)22)10-11-24-12-14-26-15-13-24/h2-9,16-17H,10-15H2,1H3/b20-16+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of 0.5 nM [3H](R)-(+)-WIN-55212-2 from Cannabinoid receptor of rat cerebellar membranes				Bioorg Med Chem Lett 5: 381-386 (1995) Article DOI: 10.1016/0960-894X(95)00040-Z BindingDB Entry DOI: 10.7270/Q2571BZN
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157507 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]-3-...) Show SMILES Cc1cc(O)ccc1-c1nn(CC=C)c2c(cccc12)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O/c1-3-9-23-17-14(5-4-6-15(17)18(19,20)21)16(22-23)13-8-7-12(24)10-11(13)2/h3-8,10,24H,1,9H2,2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257273 (CHEMBL4068562) Show SMILES Cn1c(ccc1-c1ccc(O)c(F)c1)C#N Show InChI InChI=1S/C12H9FN2O/c1-15-9(7-14)3-4-11(15)8-2-5-12(16)10(13)6-8/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157487 (4-(6-hydroxy-1-propyl-1H-indazol-3-yl)benzene-1,3-...) Show SMILES CCCn1nc(-c2ccc(O)cc2O)c2ccc(O)cc12 Show InChI InChI=1S/C16H16N2O3/c1-2-7-18-14-8-10(19)3-5-12(14)16(17-18)13-6-4-11(20)9-15(13)21/h3-6,8-9,19-21H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257268 (CHEMBL4100251) Show SMILES Cn1c(ccc1-c1ccc(O)cc1[N+]([O-])=O)C#N Show InChI InChI=1S/C12H9N3O3/c1-14-8(7-13)2-5-11(14)10-4-3-9(16)6-12(10)15(17)18/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257263 (CHEMBL4104046) Show SMILES Cn1c(ccc1-c1c(F)cc(O)cc1C#N)C#N |(32.18,-19.02,;32.14,-17.48,;30.86,-16.62,;31.29,-15.14,;32.83,-15.09,;33.36,-16.54,;34.83,-16.96,;35.94,-15.9,;35.57,-14.4,;37.42,-16.33,;37.79,-17.83,;39.27,-18.26,;36.67,-18.9,;35.2,-18.46,;34.09,-19.53,;32.97,-20.6,;29.4,-17.14,;27.95,-17.66,)| Show InChI InChI=1S/C13H8FN3O/c1-17-9(7-16)2-3-12(17)13-8(6-15)4-10(18)5-11(13)14/h2-5,18H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257324 (CHEMBL4091403) Show SMILES Cn1c(ccc1-c1cc(F)c(O)cc1F)C#N Show InChI InChI=1S/C12H8F2N2O/c1-16-7(6-15)2-3-11(16)8-4-10(14)12(17)5-9(8)13/h2-5,17H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157493 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...) Show SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C17H13F3N2O2/c1-2-8-22-16-12(4-3-5-13(16)17(18,19)20)15(21-22)11-7-6-10(23)9-14(11)24/h2-7,9,23-24H,1,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM50157505 (4-[1-(2-hydroxyethyl)-7-(trifluoromethyl)-1H-indaz...) Show SMILES OCCn1nc(-c2ccc(O)cc2)c2cccc(c12)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2/c17-16(18,19)13-3-1-2-12-14(10-4-6-11(23)7-5-10)20-21(8-9-22)15(12)13/h1-7,22-23H,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157484 (4-(1-benzyl-7-chloro-1H-indazol-3-yl)phenol | CHEM...) Show SMILES Oc1ccc(cc1)-c1nn(Cc2ccccc2)c2c(Cl)cccc12 Show InChI InChI=1S/C20H15ClN2O/c21-18-8-4-7-17-19(15-9-11-16(24)12-10-15)22-23(20(17)18)13-14-5-2-1-3-6-14/h1-12,24H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50157493 (4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...) Show SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1 Show InChI InChI=1S/C17H13F3N2O2/c1-2-8-22-16-12(4-3-5-13(16)17(18,19)20)15(21-22)11-7-6-10(23)9-14(11)24/h2-7,9,23-24H,1,8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]E2 from ERbeta ligand binding domain				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157494 (4-(1-butyl-6-hydroxy-1H-indazol-3-yl)benzene-1,3-d...) Show SMILES CCCCn1nc(-c2ccc(O)cc2O)c2ccc(O)cc12 Show InChI InChI=1S/C17H18N2O3/c1-2-3-8-19-15-9-11(20)4-6-13(15)17(18-19)14-7-5-12(21)10-16(14)22/h4-7,9-10,20-22H,2-3,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257311 (CHEMBL4060340) Show SMILES CCn1c(ccc1-c1ccc(O)cc1F)C#N Show InChI InChI=1S/C13H11FN2O/c1-2-16-9(8-15)3-6-13(16)11-5-4-10(17)7-12(11)14/h3-7,17H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157497 (4-[6-hydroxy-1-(2,2,2-trifluoroethyl)-1H-indazol-3...) Show SMILES Oc1ccc(-c2nn(CC(F)(F)F)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C15H11F3N2O3/c16-15(17,18)7-20-12-5-8(21)1-3-10(12)14(19-20)11-4-2-9(22)6-13(11)23/h1-6,21-23H,7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257310 (CHEMBL4073869) Show SMILES Cn1c(cc(Br)c1-c1ccc(O)cc1)C#N Show InChI InChI=1S/C12H9BrN2O/c1-15-9(7-14)6-11(13)12(15)8-2-4-10(16)5-3-8/h2-6,16H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157506 (4-[1-benzyl-7-(trifluoromethyl)-1H-indazol-3-yl]ph...) Show SMILES Oc1ccc(cc1)-c1nn(Cc2ccccc2)c2c(cccc12)C(F)(F)F Show InChI InChI=1S/C21H15F3N2O/c22-21(23,24)18-8-4-7-17-19(15-9-11-16(27)12-10-15)25-26(20(17)18)13-14-5-2-1-3-6-14/h1-12,27H,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157495 (4-(1-ethyl-6-hydroxy-1H-indazol-3-yl)benzene-1,3-d...) Show SMILES CCn1nc(-c2ccc(O)cc2O)c2ccc(O)cc12 Show InChI InChI=1S/C15H14N2O3/c1-2-17-13-7-9(18)3-5-11(13)15(16-17)12-6-4-10(19)8-14(12)20/h3-8,18-20H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50257267 (CHEMBL4087674) Show SMILES COC(=O)c1cc(O)ccc1-c1ccc(C#N)n1C Show InChI InChI=1S/C14H12N2O3/c1-16-9(8-15)3-6-13(16)11-5-4-10(17)7-12(11)14(18)19-2/h3-7,17H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Worldwide Research& Development , 610 Main Street, Cambridge, Massachusetts 02139, United States. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from human androgen receptor expressed in African green monkey COS cells after 3.5 hrs by scintillation and luminescen...				J Med Chem 60: 6451-6457 (2017) Article DOI: 10.1021/acs.jmedchem.7b00373 BindingDB Entry DOI: 10.7270/Q2HH6NH9
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157490 (4-[7-chloro-1-(2-hydroxyethyl)-1H-indazol-3-yl]phe...) Show SMILES OCCn1nc(-c2ccc(O)cc2)c2cccc(Cl)c12 Show InChI InChI=1S/C15H13ClN2O2/c16-13-3-1-2-12-14(10-4-6-11(20)7-5-10)17-18(8-9-19)15(12)13/h1-7,19-20H,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157492 (4-(1-cyclohexyl-6-hydroxy-1H-indazol-3-yl)benzene-...) Show SMILES Oc1ccc(-c2nn(C3CCCCC3)c3cc(O)ccc23)c(O)c1 Show InChI InChI=1S/C19H20N2O3/c22-13-6-8-15-17(10-13)21(12-4-2-1-3-5-12)20-19(15)16-9-7-14(23)11-18(16)24/h6-12,22-24H,1-5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	443	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50157499 (4-(1-methyl-6-hydroxy-1H-indazol-3-yl)benzene-1,3-...) Show SMILES Cn1nc(-c2ccc(O)cc2O)c2ccc(O)cc12 Show InChI InChI=1S/C14H12N2O3/c1-16-12-6-8(17)2-4-10(12)14(15-16)11-5-3-9(18)7-13(11)19/h2-7,17-19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	622	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcription				J Med Chem 47: 6435-8 (2004) Article DOI: 10.1021/jm049194+ BindingDB Entry DOI: 10.7270/Q2639P7B
					More data for this Ligand-Target Pair

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