Compile Data Set for Download or QSAR

Found 578 hits with Last Name = 'williams' and Initial = 'w'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068455 (CHEMBL342809 | {4-Oxo-4-[4-(3-phenyl-propyl)-piper...) Show SMILES CC(C)(C)OC(=O)NCCCC(=O)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H35N3O3/c1-22(2,3)28-21(27)23-13-7-12-20(26)25-17-15-24(16-18-25)14-8-11-19-9-5-4-6-10-19/h4-6,9-10H,7-8,11-18H2,1-3H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50180197 ((2S,3S,4R,5R)-5-(2-chloro-6-(3-iodobenzylamino)-9H...) Show SMILES CNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12 |r| Show InChI InChI=1S/C18H18ClIN6O3S/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ABMECA from human adenosine A3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 1612-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.070 BindingDB Entry DOI: 10.7270/Q2RN38QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125092 (1-Benzyl-4-(3-methoxy-benzyl)-piperazine | CHEMBL1...) Show SMILES COc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C19H24N2O/c1-22-19-9-5-8-18(14-19)16-21-12-10-20(11-13-21)15-17-6-3-2-4-7-17/h2-9,14H,10-13,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125098 (1-Benzyl-4-(3-chloro-benzyl)-piperazine | CHEMBL16...) Show SMILES Clc1cccc(CN2CCN(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C18H21ClN2/c19-18-8-4-7-17(13-18)15-21-11-9-20(10-12-21)14-16-5-2-1-3-6-16/h1-8,13H,9-12,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125099 (1-Benzyl-4-(4-methoxy-benzyl)-piperazine | 1-benzy...) Show SMILES COc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C19H24N2O/c1-22-19-9-7-18(8-10-19)16-21-13-11-20(12-14-21)15-17-5-3-2-4-6-17/h2-10H,11-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044714 (1-Butyl-4-[2-(3,4-dichloro-phenyl)-ethyl]-piperazi...) Show SMILES CCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C16H24Cl2N2/c1-2-3-7-19-9-11-20(12-10-19)8-6-14-4-5-15(17)16(18)13-14/h4-5,13H,2-3,6-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125093 (1-Benzyl-4-(3,4-dichloro-benzyl)-piperazine | CHEM...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1Cl Show InChI InChI=1S/C18H20Cl2N2/c19-17-7-6-16(12-18(17)20)14-22-10-8-21(9-11-22)13-15-4-2-1-3-5-15/h1-7,12H,8-11,13-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036227 ((2S,6S,11S)-3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hex...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3/t15-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032410 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligand				J Med Chem 38: 2986-9 (1995) BindingDB Entry DOI: 10.7270/Q2XK8DMX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036227 ((2S,6S,11S)-3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hex...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H25NO/c1-15-20-12-17-8-9-18(23)13-19(17)21(15,2)10-11-22(20)14-16-6-4-3-5-7-16/h3-9,13,15,20,23H,10-12,14H2,1-2H3/t15-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity against Sigma opioid receptor type 1 using [3H]-(+)-Pentazocine in guinea pig brain membranes				J Med Chem 42: 4621-9 (1999) BindingDB Entry DOI: 10.7270/Q2T43SBK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068432 (1-[2-(3-Nitro-phenyl)-ethyl]-4-(3-phenyl-propyl)-p...) Show SMILES [O-][N+](=O)c1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 Show InChI InChI=1S/C21H27N3O2/c25-24(26)21-10-4-8-20(18-21)11-13-23-16-14-22(15-17-23)12-5-9-19-6-2-1-3-7-19/h1-4,6-8,10,18H,5,9,11-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]-SCH-23390 from human dopamine D1 receptor expressed in HEK293 cells after 30 mins by scintillation counting				Bioorg Med Chem 20: 6366-74 (2012) Article DOI: 10.1016/j.bmc.2012.08.058 BindingDB Entry DOI: 10.7270/Q2G161X3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50082625 ((2R,6R,11R)-3-Benzyl-11-methyl-1,2,3,4,5,6-hexahyd...) Show SMILES C[C@H]1[C@H]2Cc3ccccc3[C@@H]1CCN2Cc1ccccc1 |TLB:14:13:1:9.3.4| Show InChI InChI=1S/C20H23N/c1-15-18-11-12-21(14-16-7-3-2-4-8-16)20(15)13-17-9-5-6-10-19(17)18/h2-10,15,18,20H,11-14H2,1H3/t15-,18-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Affinity against Sigma opioid receptor type 1 using [3H]-(+)-Pentazocine in guinea pig brain membranes				J Med Chem 42: 4621-9 (1999) BindingDB Entry DOI: 10.7270/Q2T43SBK
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036229 ((2S,6S,11S)-3-(4-Fluoro-benzyl)-6,11-dimethyl-1,2,...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(F)cc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H24FNO/c1-14-20-11-16-5-8-18(24)12-19(16)21(14,2)9-10-23(20)13-15-3-6-17(22)7-4-15/h3-8,12,14,20,24H,9-11,13H2,1-2H3/t14-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044713 (2-[2-(3,4-Dichloro-phenyl)-ethyl]-octahydro-pyrido...) Show SMILES Clc1ccc(CCN2CCN3CCCCC3C2)cc1Cl Show InChI InChI=1S/C16H22Cl2N2/c17-15-5-4-13(11-16(15)18)6-8-19-9-10-20-7-2-1-3-14(20)12-19/h4-5,11,14H,1-3,6-10,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50394089 (CHEMBL2158640) Show SMILES CCCN1C[C@@H](C[C@H]2[C@H]1CCc1cc(O)c(O)cc21)c1ccc(O)cc1 |r| Show InChI InChI=1S/C22H27NO3/c1-2-9-23-13-16(14-3-6-17(24)7-4-14)10-19-18-12-22(26)21(25)11-15(18)5-8-20(19)23/h3-4,6-7,11-12,16,19-20,24-26H,2,5,8-10,13H2,1H3/t16-,19-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation counting				Bioorg Med Chem 20: 6366-74 (2012) Article DOI: 10.1016/j.bmc.2012.08.058 BindingDB Entry DOI: 10.7270/Q2G161X3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068429 (1-[2-(2-Nitro-phenyl)-ethyl]-4-(3-phenyl-propyl)-p...) Show SMILES [O-][N+](=O)c1ccccc1CCN1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C21H27N3O2/c25-24(26)21-11-5-4-10-20(21)12-14-23-17-15-22(16-18-23)13-6-9-19-7-2-1-3-8-19/h1-5,7-8,10-11H,6,9,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001888 ((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...) Show SMILES CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation counting				Bioorg Med Chem 20: 6366-74 (2012) Article DOI: 10.1016/j.bmc.2012.08.058 BindingDB Entry DOI: 10.7270/Q2G161X3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000776 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...) Show SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C15H22Cl2N2/c1-2-6-18-8-10-19(11-9-18)7-5-13-3-4-14(16)15(17)12-13/h3-4,12H,2,5-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068459 (1-[2-(4-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...) Show SMILES COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H30N2O/c1-25-22-11-9-21(10-12-22)13-15-24-18-16-23(17-19-24)14-5-8-20-6-3-2-4-7-20/h2-4,6-7,9-12H,5,8,13-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044710 ((6,7-Dichloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CN(CCN1CCCC1)C1CCc2cc(Cl)c(Cl)cc2C1 Show InChI InChI=1S/C17H24Cl2N2/c1-20(8-9-21-6-2-3-7-21)15-5-4-13-11-16(18)17(19)12-14(13)10-15/h11-12,15H,2-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50003753 (6,7-Dichloro-2-(2-pyrrolidin-1-yl-ethyl)-1,2,3,4-t...) Show SMILES Clc1cc2CCN(CCN3CCCC3)Cc2cc1Cl Show InChI InChI=1S/C15H20Cl2N2/c16-14-9-12-3-6-19(11-13(12)10-15(14)17)8-7-18-4-1-2-5-18/h9-10H,1-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenates				J Med Chem 35: 4334-43 (1992) BindingDB Entry DOI: 10.7270/Q2PN94MH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068454 (1-[2-(3-Methoxy-phenyl)-ethyl]-4-(3-phenyl-propyl)...) Show SMILES COc1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 Show InChI InChI=1S/C22H30N2O/c1-25-22-11-5-9-21(19-22)12-14-24-17-15-23(16-18-24)13-6-10-20-7-3-2-4-8-20/h2-5,7-9,11,19H,6,10,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50125095 (1-Benzyl-4-(4-chloro-benzyl)-piperazine | CHEMBL16...) Show SMILES Clc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C18H21ClN2/c19-18-8-6-17(7-9-18)15-21-12-10-20(11-13-21)14-16-4-2-1-3-5-16/h1-9H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM21221 ((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...) Show SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12 Show InChI InChI=1S/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Displacement of [3H]ABMECA from human adenosine A3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 1612-6 (2008) Article DOI: 10.1016/j.bmcl.2008.01.070 BindingDB Entry DOI: 10.7270/Q2RN38QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044726 (2-[2-(3,4-Dichloro-phenyl)-ethyl]-octahydro-pyrrol...) Show SMILES Clc1ccc(CCN2CCN3CCC[C@@H]3C2)cc1Cl Show InChI InChI=1S/C15H20Cl2N2/c16-14-4-3-12(10-15(14)17)5-7-18-8-9-19-6-1-2-13(19)11-18/h3-4,10,13H,1-2,5-9,11H2/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036234 ((2S,6S,11S)-3-(2-Fluoro-benzyl)-6,11-dimethyl-1,2,...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccccc1F |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C21H24FNO/c1-14-20-11-15-7-8-17(24)12-18(15)21(14,2)9-10-23(20)13-16-5-3-4-6-19(16)22/h3-8,12,14,20,24H,9-11,13H2,1-2H3/t14-,20+,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50003748 (CHEMBL342223 | [2-(3,4-Dichloro-phenyl)-ethyl]-(1-...) Show SMILES CCN1CCCC1CN(C)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H24Cl2N2/c1-3-20-9-4-5-14(20)12-19(2)10-8-13-6-7-15(17)16(18)11-13/h6-7,11,14H,3-5,8-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenates				J Med Chem 35: 4334-43 (1992) BindingDB Entry DOI: 10.7270/Q2PN94MH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032406 (3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-m...) Show SMILES CC1C2Cc3ccc(N)cc3C1(C)CCN2Cc1ccccc1 |TLB:16:15:1:10.4.3,9:10:1:15.13.14| Show InChI InChI=1S/C21H26N2/c1-15-20-12-17-8-9-18(22)13-19(17)21(15,2)10-11-23(20)14-16-6-4-3-5-7-16/h3-9,13,15,20H,10-12,14,22H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044047 (CHEMBL109026 | N-(3,4-Dichloro-benzyl)-N,N'-dimeth...) Show SMILES CN(CCN(C)Cc1ccc(Cl)c(Cl)c1)CCN1CCCC1 Show InChI InChI=1S/C17H27Cl2N3/c1-20(11-12-22-7-3-4-8-22)9-10-21(2)14-15-5-6-16(18)17(19)13-15/h5-6,13H,3-4,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity towards sigma 1 receptor was determined in guinea pig brain membrane using [3H](+)-pentazocine as radioligand				J Med Chem 37: 314-21 (1994) BindingDB Entry DOI: 10.7270/Q20C4WFH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036238 (4-((2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,2,5,6-tet...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(cc1)C#N |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C22H24N2O/c1-15-21-11-18-7-8-19(25)12-20(18)22(15,2)9-10-24(21)14-17-5-3-16(13-23)4-6-17/h3-8,12,15,21,25H,9-11,14H2,1-2H3/t15-,21+,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032404 (6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-...) Show SMILES [#6]-[#6]1-[#6]-2-[#6]-c3ccccc3C1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |TLB:15:14:1:9.3.4,8:9:1:14.12.13| Show InChI InChI=1S/C19H27N/c1-14(2)9-11-20-12-10-19(4)15(3)18(20)13-16-7-5-6-8-17(16)19/h5-9,15,18H,10-13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044723 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-ethyl-piperazi...) Show SMILES CCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C14H20Cl2N2/c1-2-17-7-9-18(10-8-17)6-5-12-3-4-13(15)14(16)11-12/h3-4,11H,2,5-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032404 (6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-...) Show SMILES [#6]-[#6]1-[#6]-2-[#6]-c3ccccc3C1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6] |TLB:15:14:1:9.3.4,8:9:1:14.12.13| Show InChI InChI=1S/C19H27N/c1-14(2)9-11-20-12-10-19(4)15(3)18(20)13-16-7-5-6-8-17(16)19/h5-9,15,18H,10-13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044721 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-pentyl-piperaz...) Show SMILES CCCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C17H26Cl2N2/c1-2-3-4-8-20-10-12-21(13-11-20)9-7-15-5-6-16(18)17(19)14-15/h5-6,14H,2-4,7-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50044720 (1,4-Bis-[2-(3,4-dichloro-phenyl)-ethyl]-piperazine...) Show SMILES Clc1ccc(CCN2CCN(CCc3ccc(Cl)c(Cl)c3)CC2)cc1Cl Show InChI InChI=1S/C20H22Cl4N2/c21-17-3-1-15(13-19(17)23)5-7-25-9-11-26(12-10-25)8-6-16-2-4-18(22)20(24)14-16/h1-4,13-14H,5-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Ability to displace [3H](+)-pentazocine at sigma receptor in guinea pig brain membrane was determined				J Med Chem 36: 2311-20 (1993) BindingDB Entry DOI: 10.7270/Q2RF5VNP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032422 (3-Benzyl-7-chloro-6,11-dimethyl-1,2,3,4,5,6-hexahy...) Show SMILES CC1C2Cc3ccc(O)c(Cl)c3C1(C)CCN2Cc1ccccc1 |TLB:9:11:1:16.14.15,17:16:1:11.4.3| Show InChI InChI=1S/C21H24ClNO/c1-14-17-12-16-8-9-18(24)20(22)19(16)21(14,2)10-11-23(17)13-15-6-4-3-5-7-15/h3-9,14,17,24H,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligand				J Med Chem 38: 2986-9 (1995) BindingDB Entry DOI: 10.7270/Q2XK8DMX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032426 (3-Benzyl-7-bromo-6,11-dimethyl-1,2,3,4,5,6-hexahyd...) Show SMILES CC1C2Cc3ccc(O)c(Br)c3C1(C)CCN2Cc1ccccc1 |TLB:9:11:1:16.14.15,17:16:1:11.4.3| Show InChI InChI=1S/C21H24BrNO/c1-14-17-12-16-8-9-18(24)20(22)19(16)21(14,2)10-11-23(17)13-15-6-4-3-5-7-15/h3-9,14,17,24H,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity was measured on Sigma receptor type 1 using [3H]- pentazocine as radioligand				J Med Chem 38: 2986-9 (1995) BindingDB Entry DOI: 10.7270/Q2XK8DMX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50032407 ((3-Benzyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-...) Show SMILES CC1C2Cc3ccc(cc3C1(C)CCN2Cc1ccccc1)N(C)C |TLB:8:9:1:14.12.13,15:14:1:9.4.3| Show InChI InChI=1S/C23H30N2/c1-17-22-14-19-10-11-20(24(3)4)15-21(19)23(17,2)12-13-25(22)16-18-8-6-5-7-9-18/h5-11,15,17,22H,12-14,16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity measured on Sigma receptor type 1 from guinea pig brain membranes using [3H]pentazocine as radioligand.				J Med Chem 38: 2978-85 (1995) BindingDB Entry DOI: 10.7270/Q2V988RP
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50003754 ((-)-1-[2-(3,4-Dichloro-phenyl)-ethyl]-2-pyrrolidin...) Show SMILES Clc1ccc(CCN2CCC[C@H]2CN2CCCC2)cc1Cl Show InChI InChI=1S/C17H24Cl2N2/c18-16-6-5-14(12-17(16)19)7-11-21-10-3-4-15(21)13-20-8-1-2-9-20/h5-6,12,15H,1-4,7-11,13H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenates				J Med Chem 35: 4334-43 (1992) BindingDB Entry DOI: 10.7270/Q2PN94MH
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (BOVINE)	BDBM50101828 (7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Laboratories Inc. Curated by PDSP Ki Database									J Pharmacol Exp Ther 286: 1094-102 (1998) BindingDB Entry DOI: 10.7270/Q2KK99BC
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity towards Sigma-1 receptor				Bioorg Med Chem Lett 13: 749-51 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10C4
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068430 (3-{2-[4-(3-Phenyl-propyl)-piperazin-1-yl]-ethyl}-p...) Show SMILES Nc1cccc(CCN2CCN(CCCc3ccccc3)CC2)c1 Show InChI InChI=1S/C21H29N3/c22-21-10-4-8-20(18-21)11-13-24-16-14-23(15-17-24)12-5-9-19-6-2-1-3-7-19/h1-4,6-8,10,18H,5,9,11-17,22H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50047726 ((4-Iodo-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-a...) Show SMILES CN(CCN1CCCC1)Cc1ccc(I)cc1 Show InChI InChI=1S/C14H21IN2/c1-16(10-11-17-8-2-3-9-17)12-13-4-6-14(15)7-5-13/h4-7H,2-3,8-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- Pentazocine				J Med Chem 36: 566-71 (1993) BindingDB Entry DOI: 10.7270/Q2DV1KH3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036241 ((2S,6S,11S)-6,11-Dimethyl-3-(4-methyl-benzyl)-1,2,...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(C)cc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C22H27NO/c1-15-4-6-17(7-5-15)14-23-11-10-22(3)16(2)21(23)12-18-8-9-19(24)13-20(18)22/h4-9,13,16,21,24H,10-12,14H2,1-3H3/t16-,21+,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenates				J Med Chem 35: 4334-43 (1992) BindingDB Entry DOI: 10.7270/Q2PN94MH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was evaluated against sigma-1 binding site in guinea pig,using [3H]- -(+)- Pentazocine				J Med Chem 36: 566-71 (1993) BindingDB Entry DOI: 10.7270/Q2DV1KH3
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity towards sigma 1 receptor was determined in guinea pig brain membrane using [3H](+)-pentazocine as radioligand				J Med Chem 37: 314-21 (1994) BindingDB Entry DOI: 10.7270/Q20C4WFH
					More data for this Ligand-Target Pair

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