Compile Data Set for Download or QSAR

Found 166 hits with Last Name = 'brooks' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50432188 (CHEMBL2346976) Show SMILES CC(=O)N1CCN(CCOc2ccc(cc2)C2CCN(CC2)C2=Nn3c(CC2)nnc3C(F)(F)F)CC1 |t:24| Show InChI InChI=1S/C25H32F3N7O2/c1-18(36)33-14-12-32(13-15-33)16-17-37-21-4-2-19(3-5-21)20-8-10-34(11-9-20)23-7-6-22-29-30-24(25(26,27)28)35(22)31-23/h2-5,20H,6-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]R1881 from full length androgen receptor in human LNCAP cells				Bioorg Med Chem Lett 23: 1945-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.056 BindingDB Entry DOI: 10.7270/Q21J9C5N
					More data for this Ligand-Target Pair
Androgen receptor (Rattus norvegicus (Rat))	BDBM50432188 (CHEMBL2346976) Show SMILES CC(=O)N1CCN(CCOc2ccc(cc2)C2CCN(CC2)C2=Nn3c(CC2)nnc3C(F)(F)F)CC1 |t:24| Show InChI InChI=1S/C25H32F3N7O2/c1-18(36)33-14-12-32(13-15-33)16-17-37-21-4-2-19(3-5-21)20-8-10-34(11-9-20)23-7-6-22-29-30-24(25(26,27)28)35(22)31-23/h2-5,20H,6-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to rat androgen receptor ligand binding domain by fluorescence polarization assay				Bioorg Med Chem Lett 23: 1945-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.056 BindingDB Entry DOI: 10.7270/Q21J9C5N
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329079 (CHEMBL1270280 | N2-(2,6-dimorpholinopyridin-4-yl)-...) Show SMILES CN(c1ccnc(Nc2cc(nc(c2)N2CCOCC2)N2CCOCC2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C25H29N9O2/c1-32(21-4-2-3-20-19(21)17-27-31-20)22-5-6-26-25(30-22)28-18-15-23(33-7-11-35-12-8-33)29-24(16-18)34-9-13-36-14-10-34/h2-6,15-17H,7-14H2,1H3,(H,27,31)(H,26,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329070 (CHEMBL1269858 | N2-(3,5-dimorpholinophenyl)-N4-(1H...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C26H30N8O2/c1-32(24-4-2-3-23-22(24)18-28-31-23)25-5-6-27-26(30-25)29-19-15-20(33-7-11-35-12-8-33)17-21(16-19)34-9-13-36-14-10-34/h2-6,15-18H,7-14H2,1H3,(H,28,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340570 ((2-chloro-5-((2-(3,5-dimorpholinophenylamino)pyrim...) Show SMILES CN(c1ccc(Cl)c(CO)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H31ClN6O3/c1-31(21-2-3-24(27)19(14-21)18-34)25-4-5-28-26(30-25)29-20-15-22(32-6-10-35-11-7-32)17-23(16-20)33-8-12-36-13-9-33/h2-5,14-17,34H,6-13,18H2,1H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340566 (CHEMBL1762535 | N2-(3,5-dimorpholinophenyl)-N4-(5-...) Show SMILES COc1cncc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H31N7O3/c1-30(22-16-23(33-2)18-26-17-22)24-3-4-27-25(29-24)28-19-13-20(31-5-9-34-10-6-31)15-21(14-19)32-7-11-35-12-8-32/h3-4,13-18H,5-12H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340572 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES COc1cc(CO)cc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C27H34N6O4/c1-31(22-13-20(19-34)14-25(18-22)35-2)26-3-4-28-27(30-26)29-21-15-23(32-5-9-36-10-6-32)17-24(16-21)33-7-11-37-12-8-33/h3-4,13-18,34H,5-12,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340576 (CHEMBL1762525 | N2-(3,5-dimorpholinophenyl)-N4-(3-...) Show SMILES COc1cccc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H32N6O3/c1-30(21-4-3-5-24(19-21)33-2)25-6-7-27-26(29-25)28-20-16-22(31-8-12-34-13-9-31)18-23(17-20)32-10-14-35-15-11-32/h3-7,16-19H,8-15H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340551 ((3-(isopropyl(2-(3-(methylsulfonyl)-5-morpholinoph...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C26H33N5O4S/c1-18(2)31(24-13-20(17-32)6-5-19(24)3)25-7-8-27-26(29-25)28-21-14-22(30-9-11-35-12-10-30)16-23(15-21)36(4,33)34/h5-8,13-16,18,32H,9-12,17H2,1-4H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329080 (CHEMBL1270378 | N2-(2,6-dimorpholinopyrimidin-4-yl...) Show SMILES CN(c1ccnc(Nc2cc(nc(n2)N2CCOCC2)N2CCOCC2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C24H28N10O2/c1-32(19-4-2-3-18-17(19)16-26-31-18)21-5-6-25-23(29-21)27-20-15-22(33-7-11-35-12-8-33)30-24(28-20)34-9-13-36-14-10-34/h2-6,15-16H,7-14H2,1H3,(H,26,31)(H,25,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340555 ((4-methyl-3-(methyl(2-(3-(methylsulfonyl)-5-morpho...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C24H29N5O4S/c1-17-4-5-18(16-30)12-22(17)28(2)23-6-7-25-24(27-23)26-19-13-20(29-8-10-33-11-9-29)15-21(14-19)34(3,31)32/h4-7,12-15,30H,8-11,16H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340571 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H34N6O3/c1-20-3-4-21(19-34)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-11-35-12-8-32)18-24(17-22)33-9-13-36-14-10-33/h3-6,15-18,34H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340562 ((4-methyl-3-(methyl(2-(3-(4-methylpiperazin-1-yl)-...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCN(C)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H37N7O2/c1-21-4-5-22(20-36)16-26(21)33(3)27-6-7-29-28(31-27)30-23-17-24(34-10-8-32(2)9-11-34)19-25(18-23)35-12-14-37-15-13-35/h4-7,16-19,36H,8-15,20H2,1-3H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340554 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-3-34(26-16-22(20-35)5-4-21(26)2)27-6-7-29-28(31-27)30-23-17-24(32-8-12-36-13-9-32)19-25(18-23)33-10-14-37-15-11-33/h4-7,16-19,35H,3,8-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50293247 (CHEMBL468970 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...) Show SMILES Clc1ccc2OCOc2c1Nc1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H27ClN6O4/c26-20-1-2-21-24(36-16-35-21)23(20)29-22-3-4-27-25(30-22)28-17-13-18(31-5-9-33-10-6-31)15-19(14-17)32-7-11-34-12-8-32/h1-4,13-15H,5-12,16H2,(H2,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329079 (CHEMBL1270280 | N2-(2,6-dimorpholinopyridin-4-yl)-...) Show SMILES CN(c1ccnc(Nc2cc(nc(c2)N2CCOCC2)N2CCOCC2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C25H29N9O2/c1-32(21-4-2-3-20-19(21)17-27-31-20)22-5-6-26-25(30-22)28-18-15-23(33-7-11-35-12-8-33)29-24(16-18)34-9-13-36-14-10-34/h2-6,15-17H,7-14H2,1H3,(H,27,31)(H,26,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340556 ((3-((2-(3-methoxy-5-morpholinophenylamino)pyrimidi...) Show SMILES COc1cc(Nc2nccc(n2)N(C)c2cc(CO)ccc2C)cc(c1)N1CCOCC1 Show InChI InChI=1S/C24H29N5O3/c1-17-4-5-18(16-30)12-22(17)28(2)23-6-7-25-24(27-23)26-19-13-20(15-21(14-19)31-3)29-8-10-32-11-9-29/h4-7,12-15,30H,8-11,16H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340553 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C29H38N6O3/c1-21(2)35(27-16-23(20-36)5-4-22(27)3)28-6-7-30-29(32-28)31-24-17-25(33-8-12-37-13-9-33)19-26(18-24)34-10-14-38-15-11-34/h4-7,16-19,21,36H,8-15,20H2,1-3H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340577 (CHEMBL1762524 | N4-(3-chlorophenyl)-N2-(3,5-dimorp...) Show SMILES CN(c1cccc(Cl)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H29ClN6O2/c1-30(21-4-2-3-19(26)15-21)24-5-6-27-25(29-24)28-20-16-22(31-7-11-33-12-8-31)18-23(17-20)32-9-13-34-14-10-32/h2-6,15-18H,7-14H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340567 (CHEMBL1762534 | N2-(3,5-dimorpholinophenyl)-N4-(6-...) Show SMILES COc1cccc(n1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H31N7O3/c1-30(22-4-3-5-24(28-22)33-2)23-6-7-26-25(29-23)27-19-16-20(31-8-12-34-13-9-31)18-21(17-19)32-10-14-35-15-11-32/h3-7,16-18H,8-15H2,1-2H3,(H,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340560 ((4-methyl-3-(methyl(2-(3-morpholino-5-(morpholinom...) Show SMILES CN(c1ccnc(Nc2cc(CN3CCOCC3)cc(c2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-21-3-4-22(20-35)17-26(21)32(2)27-5-6-29-28(31-27)30-24-15-23(19-33-7-11-36-12-8-33)16-25(18-24)34-9-13-37-14-10-34/h3-6,15-18,35H,7-14,19-20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340551 ((3-(isopropyl(2-(3-(methylsulfonyl)-5-morpholinoph...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C26H33N5O4S/c1-18(2)31(24-13-20(17-32)6-5-19(24)3)25-7-8-27-26(29-25)28-21-14-22(30-9-11-35-12-10-30)16-23(15-21)36(4,33)34/h5-8,13-16,18,32H,9-12,17H2,1-4H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340561 (4-(3-(4-((5-(hydroxymethyl)-2-methylphenyl)(methyl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCN(O)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H35N7O3/c1-20-3-4-21(19-35)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-9-34(36)10-8-32)18-24(17-22)33-11-13-37-14-12-33/h3-6,15-18,35-36H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340572 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES COc1cc(CO)cc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C27H34N6O4/c1-31(22-13-20(19-34)14-25(18-22)35-2)26-3-4-28-27(30-26)29-21-15-23(32-5-9-36-10-6-32)17-24(16-21)33-7-11-37-12-8-33/h3-4,13-18,34H,5-12,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340558 ((4-methyl-3-(methyl(2-(3-morpholino-5-(tetrahydro-...) Show SMILES CN(c1ccnc(Nc2cc(OC3CCOCC3)cc(c2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H35N5O4/c1-20-3-4-21(19-34)15-26(20)32(2)27-5-8-29-28(31-27)30-22-16-23(33-9-13-36-14-10-33)18-25(17-22)37-24-6-11-35-12-7-24/h3-5,8,15-18,24,34H,6-7,9-14,19H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340578 (CHEMBL1762523 | N2-(3,5-dimorpholinophenyl)-N4-met...) Show SMILES CN(c1cccc(C)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H32N6O2/c1-20-4-3-5-22(16-20)30(2)25-6-7-27-26(29-25)28-21-17-23(31-8-12-33-13-9-31)19-24(18-21)32-10-14-34-15-11-32/h3-7,16-19H,8-15H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340557 ((3-((2-(3-(2-methoxyethoxy)-5-morpholinophenylamin...) Show SMILES COCCOc1cc(Nc2nccc(n2)N(C)c2cc(CO)ccc2C)cc(c1)N1CCOCC1 Show InChI InChI=1S/C26H33N5O4/c1-19-4-5-20(18-32)14-24(19)30(2)25-6-7-27-26(29-25)28-21-15-22(31-8-10-34-11-9-31)17-23(16-21)35-13-12-33-3/h4-7,14-17,32H,8-13,18H2,1-3H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340550 ((3-((2-(2,6-dimorpholinopyridin-4-ylamino)pyrimidi...) Show SMILES CN(c1ccnc(Nc2cc(nc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C26H33N7O3/c1-19-3-4-20(18-34)15-22(19)31(2)23-5-6-27-26(30-23)28-21-16-24(32-7-11-35-12-8-32)29-25(17-21)33-9-13-36-14-10-33/h3-6,15-17,34H,7-14,18H2,1-2H3,(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340563 ((4-methyl-3-(methyl(2-(3-morpholino-5-(1,4-oxazepa...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-21-4-5-22(20-35)16-26(21)32(2)27-6-7-29-28(31-27)30-23-17-24(33-8-3-12-36-13-9-33)19-25(18-23)34-10-14-37-15-11-34/h4-7,16-19,35H,3,8-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329070 (CHEMBL1269858 | N2-(3,5-dimorpholinophenyl)-N4-(1H...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C26H30N8O2/c1-32(24-4-2-3-23-22(24)18-28-31-23)25-5-6-27-26(30-25)29-19-15-20(33-7-11-35-12-8-33)17-21(16-19)34-9-13-36-14-10-34/h2-6,15-18H,7-14H2,1H3,(H,28,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340574 (CHEMBL1762527 | N2-(3,5-dimorpholinophenyl)-N4-(5-...) Show SMILES COc1ccc(C)c(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C27H34N6O3/c1-20-4-5-24(34-3)19-25(20)31(2)26-6-7-28-27(30-26)29-21-16-22(32-8-12-35-13-9-32)18-23(17-21)33-10-14-36-15-11-33/h4-7,16-19H,8-15H2,1-3H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340576 (CHEMBL1762525 | N2-(3,5-dimorpholinophenyl)-N4-(3-...) Show SMILES COc1cccc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H32N6O3/c1-30(21-4-3-5-24(19-21)33-2)25-6-7-27-26(29-25)28-20-16-22(31-8-12-34-13-9-31)18-23(17-20)32-10-14-35-15-11-32/h3-7,16-19H,8-15H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340564 ((4-methyl-3-(methyl(2-(3-morpholino-5-(piperidin-1...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCCCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O2/c1-21-6-7-22(20-35)16-26(21)32(2)27-8-9-29-28(31-27)30-23-17-24(33-10-4-3-5-11-33)19-25(18-23)34-12-14-36-15-13-34/h6-9,16-19,35H,3-5,10-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340573 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CN(c1cccc(CO)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H32N6O3/c1-30(22-4-2-3-20(15-22)19-33)25-5-6-27-26(29-25)28-21-16-23(31-7-11-34-12-8-31)18-24(17-21)32-9-13-35-14-10-32/h2-6,15-18,33H,7-14,19H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340579 (CHEMBL1762522 | N2-(3,5-dimorpholinophenyl)-N4-met...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1ccccc1C Show InChI InChI=1S/C26H32N6O2/c1-20-5-3-4-6-24(20)30(2)25-7-8-27-26(29-25)28-21-17-22(31-9-13-33-14-10-31)19-23(18-21)32-11-15-34-16-12-32/h3-8,17-19H,9-16H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340555 ((4-methyl-3-(methyl(2-(3-(methylsulfonyl)-5-morpho...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)S(C)(=O)=O)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C24H29N5O4S/c1-17-4-5-18(16-30)12-22(17)28(2)23-6-7-25-24(27-23)26-19-13-20(29-8-10-33-11-9-29)15-21(14-19)34(3,31)32/h4-7,12-15,30H,8-11,16H2,1-3H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340564 ((4-methyl-3-(methyl(2-(3-morpholino-5-(piperidin-1...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCCCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O2/c1-21-6-7-22(20-35)16-26(21)32(2)27-8-9-29-28(31-27)30-23-17-24(33-10-4-3-5-11-33)19-25(18-23)34-12-14-36-15-13-34/h6-9,16-19,35H,3-5,10-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329065 (CHEMBL1271187 | N2-(3,5-dimorpholinophenyl)-N4-(1H...) Show SMILES C1CN(CCO1)c1cc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)cc(c1)N1CCOCC1 Show InChI InChI=1S/C25H28N8O2/c1-2-22(21-17-27-31-23(21)3-1)29-24-4-5-26-25(30-24)28-18-14-19(32-6-10-34-11-7-32)16-20(15-18)33-8-12-35-13-9-33/h1-5,14-17H,6-13H2,(H,27,31)(H2,26,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340552 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES COCCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C29H38N6O4/c1-22-3-4-23(21-36)17-27(22)35(11-12-37-2)28-5-6-30-29(32-28)31-24-18-25(33-7-13-38-14-8-33)20-26(19-24)34-9-15-39-16-10-34/h3-6,17-20,36H,7-16,21H2,1-2H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340571 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H34N6O3/c1-20-3-4-21(19-34)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-11-35-12-8-32)18-24(17-22)33-9-13-36-14-10-33/h3-6,15-18,34H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340577 (CHEMBL1762524 | N4-(3-chlorophenyl)-N2-(3,5-dimorp...) Show SMILES CN(c1cccc(Cl)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H29ClN6O2/c1-30(21-4-2-3-19(26)15-21)24-5-6-27-25(29-24)28-20-16-22(31-7-11-33-12-8-31)18-23(17-20)32-9-13-34-14-10-32/h2-6,15-18H,7-14H2,1H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340552 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES COCCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C29H38N6O4/c1-22-3-4-23(21-36)17-27(22)35(11-12-37-2)28-5-6-30-29(32-28)31-24-18-25(33-7-13-38-14-8-33)20-26(19-24)34-9-15-39-16-10-34/h3-6,17-20,36H,7-16,21H2,1-2H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50329076 (CHEMBL1270182 | N-(3-(4-((1H-indazol-4-yl)(methyl)...) Show SMILES CN(c1ccnc(Nc2cccc(NS(C)(=O)=O)c2)n1)c1cccc2[nH]ncc12 Show InChI InChI=1S/C19H19N7O2S/c1-26(17-8-4-7-16-15(17)12-21-24-16)18-9-10-20-19(23-18)22-13-5-3-6-14(11-13)25-29(2,27)28/h3-12,25H,1-2H3,(H,21,24)(H,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 by acoustic dispensing assay				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340553 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CC(C)N(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C29H38N6O3/c1-21(2)35(27-16-23(20-36)5-4-22(27)3)28-6-7-30-29(32-28)31-24-17-25(33-8-12-37-13-9-33)19-26(18-24)34-10-14-38-15-11-34/h4-7,16-19,21,36H,8-15,20H2,1-3H3,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340570 ((2-chloro-5-((2-(3,5-dimorpholinophenylamino)pyrim...) Show SMILES CN(c1ccc(Cl)c(CO)c1)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C26H31ClN6O3/c1-31(21-2-3-24(27)19(14-21)18-34)25-4-5-28-26(30-25)29-20-15-22(32-6-10-35-11-7-32)17-23(16-20)33-8-12-36-13-9-33/h2-5,14-17,34H,6-13,18H2,1H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340568 (CHEMBL1762533 | N2-(3,5-dimorpholinophenyl)-N4-(4-...) Show SMILES COc1ccnc(c1)N(C)c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H31N7O3/c1-30(24-18-22(33-2)3-5-26-24)23-4-6-27-25(29-23)28-19-15-20(31-7-11-34-12-8-31)17-21(16-19)32-9-13-35-14-10-32/h3-6,15-18H,7-14H2,1-2H3,(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340554 ((3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl...) Show SMILES CCN(c1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C28H36N6O3/c1-3-34(26-16-22(20-35)5-4-21(26)2)27-6-7-29-28(31-27)30-23-17-24(32-8-12-36-13-9-32)19-25(18-23)33-10-14-37-15-11-33/h4-7,16-19,35H,3,8-15,20H2,1-2H3,(H,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340550 ((3-((2-(2,6-dimorpholinopyridin-4-ylamino)pyrimidi...) Show SMILES CN(c1ccnc(Nc2cc(nc(c2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C26H33N7O3/c1-19-3-4-20(18-34)15-22(19)31(2)23-5-6-27-26(30-23)28-21-16-24(32-7-11-35-12-8-32)29-25(17-21)33-9-13-36-14-10-33/h3-6,15-17,34H,7-14,18H2,1-2H3,(H,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50293247 (CHEMBL468970 | N4-(5-chlorobenzo[d][1,3]dioxol-4-y...) Show SMILES Clc1ccc2OCOc2c1Nc1ccnc(Nc2cc(cc(c2)N2CCOCC2)N2CCOCC2)n1 Show InChI InChI=1S/C25H27ClN6O4/c26-20-1-2-21-24(36-16-35-21)23(20)29-22-3-4-27-25(30-22)28-17-13-18(31-5-9-33-10-6-31)15-19(14-17)32-7-11-34-12-8-32/h1-4,13-15H,5-12,16H2,(H2,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 20: 6242-5 (2010) Article DOI: 10.1016/j.bmcl.2010.08.100 BindingDB Entry DOI: 10.7270/Q2QR4XCB
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340549 ((3-((2-(2,6-dimorpholinopyrimidin-4-ylamino)pyrimi...) Show SMILES CN(c1ccnc(Nc2cc(nc(n2)N2CCOCC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C25H32N8O3/c1-18-3-4-19(17-34)15-20(18)31(2)22-5-6-26-24(29-22)27-21-16-23(32-7-11-35-12-8-32)30-25(28-21)33-9-13-36-14-10-33/h3-6,15-16,34H,7-14,17H2,1-2H3,(H,26,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 166 total )  |  Next  |  Last  >>

Jump to: