Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'burgoon' and Initial = 'ha'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043510 (CHEMBL3355507) Show SMILES CCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C22H22N2O3S/c1-2-24(17-18-9-5-3-6-10-18)22(25)19-13-15-21(16-14-19)28(26,27)23-20-11-7-4-8-12-20/h3-16,23H,2,17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043616 (CHEMBL3355497) Show SMILES CN(Cc1ccc(CCC(O)=O)cc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C24H24N2O5S/c1-26(17-19-9-7-18(8-10-19)11-16-23(27)28)24(29)20-12-14-22(15-13-20)32(30,31)25-21-5-3-2-4-6-21/h2-10,12-15,25H,11,16-17H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043509 (CHEMBL3355508) Show SMILES OCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C22H22N2O4S/c25-16-15-24(17-18-7-3-1-4-8-18)22(26)19-11-13-21(14-12-19)29(27,28)23-20-9-5-2-6-10-20/h1-14,23,25H,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043419 (CHEMBL3355515) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc(cc1)-c1nccn1Cc1ccccc1 Show InChI InChI=1S/C22H19N3O2S/c26-28(27,24-20-9-5-2-6-10-20)21-13-11-19(12-14-21)22-23-15-16-25(22)17-18-7-3-1-4-8-18/h1-16,24H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043623 (CHEMBL3355491) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C22H22N2O3S/c1-17-7-6-10-20(15-17)23-28(26,27)21-13-11-19(12-14-21)22(25)24(2)16-18-8-4-3-5-9-18/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043625 (CHEMBL3355489) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C21H19FN2O3S/c1-24(15-16-6-3-2-4-7-16)21(25)17-10-12-20(13-11-17)28(26,27)23-19-9-5-8-18(22)14-19/h2-14,23H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043617 (CHEMBL3355496) Show SMILES COCCOc1ccc(CN(C)C(=O)c2ccc(cc2)S(=O)(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C24H26N2O5S/c1-26(18-19-8-12-22(13-9-19)31-17-16-30-2)24(27)20-10-14-23(15-11-20)32(28,29)25-21-6-4-3-5-7-21/h3-15,25H,16-18H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043609 (CHEMBL3355501) Show SMILES CN(CC1CCN(CC1)C(=O)OC(C)(C)C)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C25H33N3O5S/c1-25(2,3)33-24(30)28-16-14-19(15-17-28)18-27(4)23(29)20-10-12-22(13-11-20)34(31,32)26-21-8-6-5-7-9-21/h5-13,19,26H,14-18H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043624 (CHEMBL3355490) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C21H19ClN2O3S/c1-24(15-16-6-3-2-4-7-16)21(25)17-10-12-20(13-11-17)28(26,27)23-19-9-5-8-18(22)14-19/h2-14,23H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043631 (CHEMBL3355483) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1F Show InChI InChI=1S/C21H19FN2O3S/c1-24(15-16-7-3-2-4-8-16)21(25)17-11-13-18(14-12-17)28(26,27)23-20-10-6-5-9-19(20)22/h2-14,23H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043501 (CHEMBL3355509) Show SMILES O=C(N(CCC#N)Cc1ccccc1)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C23H21N3O3S/c24-16-7-17-26(18-19-8-3-1-4-9-19)23(27)20-12-14-22(15-13-20)30(28,29)25-21-10-5-2-6-11-21/h1-6,8-15,25H,7,17-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043618 (CHEMBL3355495) Show SMILES CCc1ccc(CN(C)C(=O)c2ccc(cc2)S(=O)(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O3S/c1-3-18-9-11-19(12-10-18)17-25(2)23(26)20-13-15-22(16-14-20)29(27,28)24-21-7-5-4-6-8-21/h4-16,24H,3,17H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043628 (CHEMBL3355486) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C21H19FN2O3S/c1-24(15-16-5-3-2-4-6-16)21(25)17-7-13-20(14-8-17)28(26,27)23-19-11-9-18(22)10-12-19/h2-14,23H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043417 (CHEMBL3355517) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc(cc1)-c1nccnc1Cc1ccccc1 Show InChI InChI=1S/C23H19N3O2S/c27-29(28,26-20-9-5-2-6-10-20)21-13-11-19(12-14-21)23-22(24-15-16-25-23)17-18-7-3-1-4-8-18/h1-16,26H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043615 (CHEMBL3355498) Show SMILES CN(Cc1ccc(cc1)C(O)CO)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C23H24N2O5S/c1-25(15-17-7-9-18(10-8-17)22(27)16-26)23(28)19-11-13-21(14-12-19)31(29,30)24-20-5-3-2-4-6-20/h2-14,22,24,26-27H,15-16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair				3D Structure (crystal)
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043619 (CHEMBL1711204) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)N(C)c1ccccc1 Show InChI InChI=1S/C22H22N2O3S/c1-23(17-18-9-5-3-6-10-18)22(25)19-13-15-21(16-14-19)28(26,27)24(2)20-11-7-4-8-12-20/h3-16H,17H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043418 (CHEMBL3355516) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc(cc1)-c1ncccc1Cc1ccccc1 Show InChI InChI=1S/C24H20N2O2S/c27-29(28,26-22-11-5-2-6-12-22)23-15-13-20(14-16-23)24-21(10-7-17-25-24)18-19-8-3-1-4-9-19/h1-17,26H,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043543 (CHEMBL3355505) Show SMILES C[C@H](N(C)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H22N2O3S/c1-17(18-9-5-3-6-10-18)24(2)22(25)19-13-15-21(16-14-19)28(26,27)23-20-11-7-4-8-12-20/h3-17,23H,1-2H3/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043524 (CHEMBL3355506) Show SMILES C[C@@H](N(C)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C22H22N2O3S/c1-17(18-9-5-3-6-10-18)24(2)22(25)19-13-15-21(16-14-19)28(26,27)23-20-11-7-4-8-12-20/h3-17,23H,1-2H3/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043630 (CHEMBL3355484) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C22H22N2O3S/c1-17-8-6-7-11-21(17)23-28(26,27)20-14-12-19(13-15-20)22(25)24(2)16-18-9-4-3-5-10-18/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043484 (CHEMBL3355510) Show SMILES CN(C)CCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C24H27N3O3S/c1-26(2)17-18-27(19-20-9-5-3-6-10-20)24(28)21-13-15-23(16-14-21)31(29,30)25-22-11-7-4-8-12-22/h3-16,25H,17-19H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043622 (CHEMBL3355492) Show SMILES COc1cccc(NS(=O)(=O)c2ccc(cc2)C(=O)N(C)Cc2ccccc2)c1 Show InChI InChI=1S/C22H22N2O4S/c1-24(16-17-7-4-3-5-8-17)22(25)18-11-13-21(14-12-18)29(26,27)23-19-9-6-10-20(15-19)28-2/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043613 (CHEMBL3355500) Show SMILES CN(CC1CCN(CC1)C(C)=O)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C22H27N3O4S/c1-17(26)25-14-12-18(13-15-25)16-24(2)22(27)19-8-10-21(11-9-19)30(28,29)23-20-6-4-3-5-7-20/h3-11,18,23H,12-16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043629 (CHEMBL3355485) Show SMILES COc1ccccc1NS(=O)(=O)c1ccc(cc1)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C22H22N2O4S/c1-24(16-17-8-4-3-5-9-17)22(25)18-12-14-19(15-13-18)29(26,27)23-20-10-6-7-11-21(20)28-2/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043423 (CHEMBL3355511) Show SMILES NCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C22H23N3O3S/c23-15-16-25(17-18-7-3-1-4-8-18)22(26)19-11-13-21(14-12-19)29(27,28)24-20-9-5-2-6-10-20/h1-14,24H,15-17,23H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043422 (CHEMBL3355512) Show SMILES NCCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C23H25N3O3S/c24-16-7-17-26(18-19-8-3-1-4-9-19)23(27)20-12-14-22(15-13-20)30(28,29)25-21-10-5-2-6-11-21/h1-6,8-15,25H,7,16-18,24H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043421 (CHEMBL3355513) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc(cc1)-c1ocnc1Cc1ccccc1 Show InChI InChI=1S/C22H18N2O3S/c25-28(26,24-19-9-5-2-6-10-19)20-13-11-18(12-14-20)22-21(23-16-27-22)15-17-7-3-1-4-8-17/h1-14,16,24H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043614 (CHEMBL3355499) Show SMILES CN(Cc1ccc(cc1)C1CCNCC1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C26H29N3O3S/c1-29(19-20-7-9-21(10-8-20)22-15-17-27-18-16-22)26(30)23-11-13-25(14-12-23)33(31,32)28-24-5-3-2-4-6-24/h2-14,22,27-28H,15-19H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043632 (CHEMBL3355481) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(NS(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C19H18N2O3S2/c1-21(14-15-6-3-2-4-7-15)19(22)16-9-11-17(12-10-16)20-26(23,24)18-8-5-13-25-18/h2-13,20H,14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 1 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of LMIK1 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043627 (CHEMBL3355487) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccc(C)cc1 Show InChI InChI=1S/C22H22N2O3S/c1-17-8-12-20(13-9-17)23-28(26,27)21-14-10-19(11-15-21)22(25)24(2)16-18-6-4-3-5-7-18/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Abl (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of LCK (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043626 (CHEMBL3355488) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(cc2)C(=O)N(C)Cc2ccccc2)cc1 Show InChI InChI=1S/C22H22N2O4S/c1-24(16-17-6-4-3-5-7-17)22(25)18-8-14-21(15-9-18)29(26,27)23-19-10-12-20(28-2)13-11-19/h3-15,23H,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043621 (CHEMBL3355493) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(C)(C)C Show InChI InChI=1S/C25H28N2O3S/c1-25(2,3)21-11-8-12-22(17-21)26-31(29,30)23-15-13-20(14-16-23)24(28)27(4)18-19-9-6-5-7-10-19/h5-17,26H,18H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043620 (CHEMBL3355494) Show SMILES CN(C)c1cccc(NS(=O)(=O)c2ccc(cc2)C(=O)N(C)Cc2ccccc2)c1 Show InChI InChI=1S/C23H25N3O3S/c1-25(2)21-11-7-10-20(16-21)24-30(28,29)22-14-12-19(13-15-22)23(27)26(3)17-18-8-5-4-6-9-18/h4-16,24H,17H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043551 (CHEMBL3355504) Show SMILES CC(C)N1CCC(CN(C)C(=O)c2ccc(cc2)S(=O)(=O)Nc2ccccc2)CC1 Show InChI InChI=1S/C23H31N3O3S/c1-18(2)26-15-13-19(14-16-26)17-25(3)23(27)20-9-11-22(12-10-20)30(28,29)24-21-7-5-4-6-8-21/h4-12,18-19,24H,13-17H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043554 (CHEMBL3355503) Show SMILES CN(CC1CCN(C)CC1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H27N3O3S/c1-23-14-12-17(13-15-23)16-24(2)21(25)18-8-10-20(11-9-18)28(26,27)22-19-6-4-3-5-7-19/h3-11,17,22H,12-16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043562 (CHEMBL3355502) Show SMILES CN(CC1CCNCC1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C20H25N3O3S/c1-23(15-16-11-13-21-14-12-16)20(24)17-7-9-19(10-8-17)27(25,26)22-18-5-3-2-4-6-18/h2-10,16,21-22H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
LIM domain kinase 2 (Homo sapiens (Human))	BDBM50043420 (CHEMBL3355514) Show SMILES O=c1ccnc(-c2ccc(cc2)S(=O)(=O)Nc2ccccc2)n1Cc1ccccc1 Show InChI InChI=1S/C23H19N3O3S/c27-22-15-16-24-23(26(22)17-18-7-3-1-4-8-18)19-11-13-21(14-12-19)30(28,29)25-20-9-5-2-6-10-20/h1-16,25H,17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human full-length LIMK2 expressed in Sf9 cells assessed as incorporation of [33P] from ATP into biotinylated-cofilin substrate in prese...				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of MAP4K5 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CDK1 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CDK2 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CHK2 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Jak2 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Jak3 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Flt1 (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Homo sapiens (Human))	BDBM50043416 (CHEMBL3355482) Show SMILES CN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C21H20N2O3S/c1-23(16-17-8-4-2-5-9-17)21(24)18-12-14-20(15-13-18)27(25,26)22-19-10-6-3-7-11-19/h2-15,22H,16H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Fgr (unknown origin) in presence of 1 mM ATP				ACS Med Chem Lett 6: 53-7 (2015) Article DOI: 10.1021/ml500242y BindingDB Entry DOI: 10.7270/Q2SQ9207
					More data for this Ligand-Target Pair

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