Compile Data Set for Download or QSAR

Found 101 hits with Last Name = 'dumaître' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050597 (1-Ethyl-3-methyl-6-(5-nitro-2-propoxy-phenyl)-1,5-...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)[N+]([O-])=O Show InChI InChI=1S/C17H19N5O4/c1-4-8-26-13-7-6-11(22(24)25)9-12(13)15-18-16-14(17(23)19-15)10(3)20-21(16)5-2/h6-7,9H,4-5,8H2,1-3H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050584 (1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...) Show SMILES CCCOc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C23H23FN6O3/c1-4-11-33-18-10-9-16(26-23(32)25-15-7-5-14(24)6-8-15)12-17(18)20-27-21-19(22(31)28-20)13(2)29-30(21)3/h5-10,12H,4,11H2,1-3H3,(H2,25,26,32)(H,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050582 (CHEMBL43443 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...) Show SMILES CCCOc1ccc(NC(C)=O)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C18H21N5O3/c1-5-8-26-14-7-6-12(19-11(3)24)9-13(14)16-20-17-15(18(25)21-16)10(2)22-23(17)4/h6-7,9H,5,8H2,1-4H3,(H,19,24)(H,20,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050619 (3-Methyl-6-(2-propoxy-phenyl)-1-propyl-1,5-dihydro...) Show SMILES CCCOc1ccccc1-c1nc2n(CCC)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C18H22N4O2/c1-4-10-22-17-15(12(3)21-22)18(23)20-16(19-17)13-8-6-7-9-14(13)24-11-5-2/h6-9H,4-5,10-11H2,1-3H3,(H,19,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050605 (CHEMBL297864 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-...) Show SMILES CCCOc1ccc(NC(N)=S)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H20N6O2S/c1-4-7-25-12-6-5-10(19-17(18)26)8-11(12)14-20-15-13(16(24)21-14)9(2)22-23(15)3/h5-6,8H,4,7H2,1-3H3,(H3,18,19,26)(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050627 (CHEMBL298478 | Thiophene-2-carboxylic acid [3-(1,3...) Show SMILES CCCOc1ccc(NC(=O)c2cccs2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C21H21N5O3S/c1-4-9-29-15-8-7-13(22-20(27)16-6-5-10-30-16)11-14(15)18-23-19-17(21(28)24-18)12(2)25-26(19)3/h5-8,10-11H,4,9H2,1-3H3,(H,22,27)(H,23,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050626 (1-Ethyl-3-methyl-6-[5-(5-phenyl-1H-[1,2,4]triazol-...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)-c1nnc([nH]1)-c1ccccc1 Show InChI InChI=1S/C25H25N7O2/c1-4-13-34-19-12-11-17(22-26-21(29-30-22)16-9-7-6-8-10-16)14-18(19)23-27-24-20(25(33)28-23)15(3)31-32(24)5-2/h6-12,14H,4-5,13H2,1-3H3,(H,26,29,30)(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050577 (1-Ethyl-3-methyl-6-[2-propoxy-5-(2-pyridin-3-yl-th...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)-c1csc(n1)-c1cccnc1 Show InChI InChI=1S/C25H24N6O2S/c1-4-11-33-20-9-8-16(19-14-34-25(27-19)17-7-6-10-26-13-17)12-18(20)22-28-23-21(24(32)29-22)15(3)30-31(23)5-2/h6-10,12-14H,4-5,11H2,1-3H3,(H,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050622 (1-Ethyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro-...) Show SMILES CCCOc1ccccc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H20N4O2/c1-4-10-23-13-9-7-6-8-12(13)15-18-16-14(17(22)19-15)11(3)20-21(16)5-2/h6-9H,4-5,10H2,1-3H3,(H,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050579 (CHEMBL42886 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1...) Show SMILES CCCOc1ccc(NC(N)=O)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H20N6O3/c1-4-7-26-12-6-5-10(19-17(18)25)8-11(12)14-20-15-13(16(24)21-14)9(2)22-23(15)3/h5-6,8H,4,7H2,1-3H3,(H3,18,19,25)(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050595 (1-Ethyl-3-methyl-6-[5-(4-methyl-thiazol-2-yl)-2-pr...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)-c1nc(C)cs1 Show InChI InChI=1S/C21H23N5O2S/c1-5-9-28-16-8-7-14(21-22-12(3)11-29-21)10-15(16)18-23-19-17(20(27)24-18)13(4)25-26(19)6-2/h7-8,10-11H,5-6,9H2,1-4H3,(H,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050618 (CHEMBL291178 | [3-(1,3-Dimethyl-4-oxo-4,5-dihydro-...) Show SMILES CCCOc1ccc(NC(=O)OC)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C18H21N5O4/c1-5-8-27-13-7-6-11(19-18(25)26-4)9-12(13)15-20-16-14(17(24)21-15)10(2)22-23(16)3/h6-7,9H,5,8H2,1-4H3,(H,19,25)(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050620 (CHEMBL46771 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...) Show SMILES CCCOc1ccc(NC(=O)c2ccc(F)cc2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C23H22FN5O3/c1-4-11-32-18-10-9-16(25-22(30)14-5-7-15(24)8-6-14)12-17(18)20-26-21-19(23(31)27-20)13(2)28-29(21)3/h5-10,12H,4,11H2,1-3H3,(H,25,30)(H,26,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050603 (1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydr o-1H-pyrazolo[...) Show SMILES CCCOc1ccc(NC(=S)NC(=O)OCC)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C20H24N6O4S/c1-5-9-30-14-8-7-12(21-19(31)24-20(28)29-6-2)10-13(14)16-22-17-15(18(27)23-16)11(3)25-26(17)4/h7-8,10H,5-6,9H2,1-4H3,(H,22,23,27)(H2,21,24,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050580 (CHEMBL416267 | N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-di...) Show SMILES CCCOc1ccc(NC(C)=O)cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C19H23N5O3/c1-5-9-27-15-8-7-13(20-12(4)25)10-14(15)17-21-18-16(19(26)22-17)11(3)23-24(18)6-2/h7-8,10H,5-6,9H2,1-4H3,(H,20,25)(H,21,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050611 (1,3-Dimethyl-6-[5-(2-methyl-thiazol-4-yl)-2-propox...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1csc(C)n1 Show InChI InChI=1S/C20H21N5O2S/c1-5-8-27-16-7-6-13(15-10-28-12(3)21-15)9-14(16)18-22-19-17(20(26)23-18)11(2)24-25(19)4/h6-7,9-10H,5,8H2,1-4H3,(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050593 (1,3-Dimethyl-6-[5-(2-phenyl-thiazol-4-yl)-2-propox...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C25H23N5O2S/c1-4-12-32-20-11-10-17(19-14-33-25(26-19)16-8-6-5-7-9-16)13-18(20)22-27-23-21(24(31)28-22)15(2)29-30(23)3/h5-11,13-14H,4,12H2,1-3H3,(H,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050590 (1,3-Dimethyl-6-[5-(4-methyl-thiazol-2-yl)-2-propox...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1nc(C)cs1 Show InChI InChI=1S/C20H21N5O2S/c1-5-8-27-15-7-6-13(20-21-11(2)10-28-20)9-14(15)17-22-18-16(19(26)23-17)12(3)24-25(18)4/h6-7,9-10H,5,8H2,1-4H3,(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050598 (CHEMBL45367 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...) Show SMILES CCCOc1ccc(NS(C)(=O)=O)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H21N5O4S/c1-5-8-26-13-7-6-11(21-27(4,24)25)9-12(13)15-18-16-14(17(23)19-15)10(2)20-22(16)3/h6-7,9,21H,5,8H2,1-4H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050576 (1,3-Dimethyl-6-(2-propoxy-5-thiazol-2-yl-phenyl)-1...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1nccs1 Show InChI InChI=1S/C19H19N5O2S/c1-4-8-26-14-6-5-12(19-20-7-9-27-19)10-13(14)16-21-17-15(18(25)22-16)11(2)23-24(17)3/h5-7,9-10H,4,8H2,1-3H3,(H,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050614 (1-Ethyl-3-methyl-6-[5-(2-phenyl-thiazol-4-yl)-2-pr...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)-c1csc(n1)-c1ccccc1 Show InChI InChI=1S/C26H25N5O2S/c1-4-13-33-21-12-11-18(20-15-34-26(27-20)17-9-7-6-8-10-17)14-19(21)23-28-24-22(25(32)29-23)16(3)30-31(24)5-2/h6-12,14-15H,4-5,13H2,1-3H3,(H,28,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050585 (1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...) Show SMILES CCCOc1ccc(NC(=S)NCC)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C19H24N6O2S/c1-5-9-27-14-8-7-12(21-19(28)20-6-2)10-13(14)16-22-17-15(18(26)23-16)11(3)24-25(17)4/h7-8,10H,5-6,9H2,1-4H3,(H2,20,21,28)(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050610 (1-Ethyl-3-methyl-6-[5-(2-methyl-thiazol-4-yl)-2-pr...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)-c1csc(C)n1 Show InChI InChI=1S/C21H23N5O2S/c1-5-9-28-17-8-7-14(16-11-29-13(4)22-16)10-15(17)19-23-20-18(21(27)24-19)12(3)25-26(20)6-2/h7-8,10-11H,5-6,9H2,1-4H3,(H,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050596 (1-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro-1H-pyrazolo[3...) Show SMILES CCCOc1ccc(NC(=O)NCC)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C19H24N6O3/c1-5-9-28-14-8-7-12(21-19(27)20-6-2)10-13(14)16-22-17-15(18(26)23-16)11(3)24-25(17)4/h7-8,10H,5-6,9H2,1-4H3,(H2,20,21,27)(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050592 (CHEMBL46621 | N-[3-(1,3-Dimethyl-4-oxo-4,5-dihydro...) Show SMILES CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C23H31N7O3/c1-5-12-33-18-7-6-16(24-19(31)14-30-10-8-28(3)9-11-30)13-17(18)21-25-22-20(23(32)26-21)15(2)27-29(22)4/h6-7,13H,5,8-12,14H2,1-4H3,(H,24,31)(H,25,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050624 (6-(5-Dimethylamino-2-propoxy-phenyl)-1-ethyl-3-met...) Show SMILES CCCOc1ccc(cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1)N(C)C Show InChI InChI=1S/C19H25N5O2/c1-6-10-26-15-9-8-13(23(4)5)11-14(15)17-20-18-16(19(25)21-17)12(3)22-24(18)7-2/h8-9,11H,6-7,10H2,1-5H3,(H,20,21,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050600 (CHEMBL298294 | N-[3-(1-Ethyl-3-methyl-4-oxo-4,5-di...) Show SMILES CCCOc1ccc(NS(C)(=O)=O)cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C18H23N5O4S/c1-5-9-27-14-8-7-12(22-28(4,25)26)10-13(14)16-19-17-15(18(24)20-16)11(3)21-23(17)6-2/h7-8,10,22H,5-6,9H2,1-4H3,(H,19,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050599 (1,3-Dimethyl-6-[5-(5-methyl-thiophen-2-yl)-2-propo...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1ccc(C)s1 Show InChI InChI=1S/C21H22N4O2S/c1-5-10-27-16-8-7-14(17-9-6-12(2)28-17)11-15(16)19-22-20-18(21(26)23-19)13(3)24-25(20)4/h6-9,11H,5,10H2,1-4H3,(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050575 (1,3-Dimethyl-6-(5-nitro-2-propoxy-phenyl)-1,5-dihy...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)[N+]([O-])=O Show InChI InChI=1S/C16H17N5O4/c1-4-7-25-12-6-5-10(21(23)24)8-11(12)14-17-15-13(16(22)18-14)9(2)19-20(15)3/h5-6,8H,4,7H2,1-3H3,(H,17,18,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050621 (1,3-Dimethyl-6-[5-(2-morpholin-4-yl-acetyl)-2-prop...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)C(=O)CN1CCOCC1 Show InChI InChI=1S/C22H27N5O4/c1-4-9-31-18-6-5-15(17(28)13-27-7-10-30-11-8-27)12-16(18)20-23-21-19(22(29)24-20)14(2)25-26(21)3/h5-6,12H,4,7-11,13H2,1-3H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050615 (6-(5-Dimethylamino-2-propoxy-phenyl)-1,3-dimethyl-...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)N(C)C Show InChI InChI=1S/C18H23N5O2/c1-6-9-25-14-8-7-12(22(3)4)10-13(14)16-19-17-15(18(24)20-16)11(2)21-23(17)5/h7-8,10H,6,9H2,1-5H3,(H,19,20,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050581 (1,3-Dimethyl-6-(2-propoxy-5-thiophen-2-yl-phenyl)-...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1cccs1 Show InChI InChI=1S/C20H20N4O2S/c1-4-9-26-15-8-7-13(16-6-5-10-27-16)11-14(15)18-21-19-17(20(25)22-18)12(2)23-24(19)3/h5-8,10-11H,4,9H2,1-3H3,(H,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050602 (6-[5-(5-Amino-1H-[1,2,4]triazol-3-ylamino)-2-propo...) Show SMILES CCCOc1ccc(Nc2nnc(N)[nH]2)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C18H21N9O2/c1-4-7-29-12-6-5-10(20-18-23-17(19)24-25-18)8-11(12)14-21-15-13(16(28)22-14)9(2)26-27(15)3/h5-6,8H,4,7H2,1-3H3,(H,21,22,28)(H4,19,20,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050616 (1-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro-...) Show SMILES CCCCn1nc(C)c2c1nc([nH]c2=O)-c1ccccc1OCCC Show InChI InChI=1S/C19H24N4O2/c1-4-6-11-23-18-16(13(3)22-23)19(24)21-17(20-18)14-9-7-8-10-15(14)25-12-5-2/h7-10H,4-6,11-12H2,1-3H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050617 (6-(5-Amino-2-propoxy-phenyl)-1-ethyl-3-methyl-1,5-...) Show SMILES CCCOc1ccc(N)cc1-c1nc2n(CC)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H21N5O2/c1-4-8-24-13-7-6-11(18)9-12(13)15-19-16-14(17(23)20-15)10(3)21-22(16)5-2/h6-7,9H,4-5,8,18H2,1-3H3,(H,19,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050574 (3-Methyl-6-(2-propoxy-phenyl)-1-(2,2,2-trifluoro-e...) Show SMILES CCCOc1ccccc1-c1nc2n(CC(F)(F)F)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C17H17F3N4O2/c1-3-8-26-12-7-5-4-6-11(12)14-21-15-13(16(25)22-14)10(2)23-24(15)9-17(18,19)20/h4-7H,3,8-9H2,1-2H3,(H,21,22,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050607 (1,3-Dimethyl-6-(2-propoxy-phenyl)-1,5-dihydro-pyra...) Show SMILES CCCOc1ccccc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C16H18N4O2/c1-4-9-22-12-8-6-5-7-11(12)14-17-15-13(16(21)18-14)10(2)19-20(15)3/h5-8H,4,9H2,1-3H3,(H,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050606 (6-(5-Amino-2-propoxy-phenyl)-1,3-dimethyl-1,5-dihy...) Show SMILES CCCOc1ccc(N)cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C16H19N5O2/c1-4-7-23-12-6-5-10(17)8-11(12)14-18-15-13(16(22)19-14)9(2)20-21(15)3/h5-6,8H,4,7,17H2,1-3H3,(H,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050589 (1,3-Dimethyl-6-[5-(5-phenyl-1H-[1,2,4]triazol-3-yl...) Show SMILES CCCOc1ccc(cc1-c1nc2n(C)nc(C)c2c(=O)[nH]1)-c1nnc([nH]1)-c1ccccc1 Show InChI InChI=1S/C24H23N7O2/c1-4-12-33-18-11-10-16(21-25-20(28-29-21)15-8-6-5-7-9-15)13-17(18)22-26-23-19(24(32)27-22)14(2)30-31(23)3/h5-11,13H,4,12H2,1-3H3,(H,25,28,29)(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050588 (1-tert-Butyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dih...) Show SMILES CCCOc1ccccc1-c1nc2n(nc(C)c2c(=O)[nH]1)C(C)(C)C Show InChI InChI=1S/C19H24N4O2/c1-6-11-25-14-10-8-7-9-13(14)16-20-17-15(18(24)21-16)12(2)22-23(17)19(3,4)5/h7-10H,6,11H2,1-5H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050608 (6-(2-Ethoxy-phenyl)-1,3-dimethyl-1,5-dihydro-pyraz...) Show SMILES CCOc1ccccc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C15H16N4O2/c1-4-21-11-8-6-5-7-10(11)13-16-14-12(15(20)17-13)9(2)18-19(14)3/h5-8H,4H2,1-3H3,(H,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050583 (3-Methyl-6-(2-propoxy-phenyl)-5H-isothiazolo[3,4-d...) Show SMILES CCCOc1ccccc1-c1nc2nsc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C15H15N3O2S/c1-3-8-20-11-7-5-4-6-10(11)13-16-14-12(15(19)17-13)9(2)21-18-14/h4-7H,3,8H2,1-2H3,(H,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050612 (6-(2-Isopropoxy-phenyl)-1,3-dimethyl-1,5-dihydro-p...) Show SMILES CC(C)Oc1ccccc1-c1nc2n(C)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C16H18N4O2/c1-9(2)22-12-8-6-5-7-11(12)14-17-15-13(16(21)18-14)10(3)19-20(15)4/h5-9H,1-4H3,(H,17,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050613 (2-(2-Propoxy-phenyl)-3H-pyrido[4,3-d]pyrimidin-4-o...) Show SMILES CCCOc1ccccc1-c1nc2ccncc2c(=O)[nH]1 Show InChI InChI=1S/C16H15N3O2/c1-2-9-21-14-6-4-3-5-11(14)15-18-13-7-8-17-10-12(13)16(20)19-15/h3-8,10H,2,9H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050587 (2-(2-Propoxy-phenyl)-3H-thieno[3,2-d]pyrimidin-4-o...) Show SMILES CCCOc1ccccc1-c1nc2ccsc2c(=O)[nH]1 Show InChI InChI=1S/C15H14N2O2S/c1-2-8-19-12-6-4-3-5-10(12)14-16-11-7-9-20-13(11)15(18)17-14/h3-7,9H,2,8H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050578 (5-Methyl-2-(2-propoxy-phenyl)-3H-thieno[2,3-d]pyri...) Show SMILES CCCOc1ccccc1-c1nc2scc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C16H16N2O2S/c1-3-8-20-12-7-5-4-6-11(12)14-17-15(19)13-10(2)9-21-16(13)18-14/h4-7,9H,3,8H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050594 (2-(2-Propoxy-phenyl)-3H-pyrido[3,4-d]pyrimidin-4-o...) Show SMILES CCCOc1ccccc1-c1nc2cnccc2c(=O)[nH]1 Show InChI InChI=1S/C16H15N3O2/c1-2-9-21-14-6-4-3-5-12(14)15-18-13-10-17-8-7-11(13)16(20)19-15/h3-8,10H,2,9H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050609 (1-Benzyl-3-methyl-6-(2-propoxy-phenyl)-1,5-dihydro...) Show SMILES CCCOc1ccccc1-c1nc2n(Cc3ccccc3)nc(C)c2c(=O)[nH]1 Show InChI InChI=1S/C22H22N4O2/c1-3-13-28-18-12-8-7-11-17(18)20-23-21-19(22(27)24-20)15(2)25-26(21)14-16-9-5-4-6-10-16/h4-12H,3,13-14H2,1-2H3,(H,23,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50040377 (2-(2-Propoxy-phenyl)-1,7-dihydro-purin-6-one | 2-(...) Show SMILES CCCOc1ccccc1-c1nc2nc[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C14H14N4O2/c1-2-7-20-10-6-4-3-5-9(10)12-17-13-11(14(19)18-12)15-8-16-13/h3-6,8H,2,7H2,1H3,(H2,15,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50050591 (7-Methyl-2-(2-propoxy-phenyl)-3H-thieno[3,2-d]pyri...) Show SMILES CCCOc1ccccc1-c1nc2c(C)csc2c(=O)[nH]1 Show InChI InChI=1S/C16H16N2O2S/c1-3-8-20-12-7-5-4-6-11(12)15-17-13-10(2)9-21-14(13)16(19)18-15/h4-7,9H,3,8H2,1-2H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Laboratories Glaxo Wellcome Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from human				J Med Chem 39: 1635-44 (1996) Article DOI: 10.1021/jm950812j BindingDB Entry DOI: 10.7270/Q2057F1T
					More data for this Ligand-Target Pair

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