Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Squalene synthase (Rattus norvegicus) | BDBM50291312 (4-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50075719 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291315 (5-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291311 (6-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291316 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Homo sapiens (Human)) | BDBM50075719 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against human microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291317 (CHEMBL154472 | [3-Allyl-4-(3-hydroxy-1-aza-bicyclo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291318 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291313 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291319 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50291314 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | >250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against rat microsomal quinuclidine squalene synthase (SQS) | Bioorg Med Chem Lett 7: 597-600 (1997) Article DOI: 10.1016/S0960-894X(97)00053-X BindingDB Entry DOI: 10.7270/Q2C24WFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029174 (CHEMBL131973 | N-(1-methylethyl)-3-[(3-prop-2-en-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 0.00400 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029177 (CHEMBL134337 | Propionic acid 3-allyl-4-(3-isoprop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029166 (Acetaldehyde O-[3-allyl-4-(3-isopropylamino-propox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029171 (CHEMBL341371 | N-[3-Benzyl-4-(3-isopropylamino-pro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029159 (CHEMBL132881 | [3-(2-Allyl-4-butoxy-phenoxy)-propy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029179 (1-[3-Allyl-4-(3-isopropylamino-propoxy)-phenyl]-bu...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052343 (3-Biphenyl-4-ylethynyl-1-aza-bicyclo[2.2.2]octan-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029163 (CHEMBL340992 | Propionic acid 4-(3-isopropylamino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052350 (3-((E)-2-Biphenyl-4-yl-vinyl)-1-aza-bicyclo[2.2.2]...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029170 (1-[3-Allyl-4-(2-hydroxy-3-isopropylamino-propoxy)-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052342 (3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029161 (CHEMBL433864 | N-{3-Allyl-4-[3-(isopropyl-methyl-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50075719 (3-[3-Allyl-4-(3-hydroxy-1-aza-bicyclo[2.2.2]oct-3-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Compound was measured for the inhibition of rat microsomal squalene synthase enzyme | J Med Chem 42: 1306-11 (1999) Article DOI: 10.1021/jm990038q BindingDB Entry DOI: 10.7270/Q23X85TQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052353 (3-(4-Benzothiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052355 (3-(2-Biphenyl-4-yl-ethyl)-1-aza-bicyclo[2.2.2]octa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052377 (3-(Biphenyl-4-ylsulfanylmethyl)-1-aza-bicyclo[2.2....) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034758 ((E)-7-(3-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034762 ((E)-7-(4-{6-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034767 ((E)-7-(4-{5-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052376 (3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octane | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50029172 (CHEMBL131930 | [3-(2-Benzyl-phenoxy)-propyl]-isopr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of rat microsomal squalene synthase | J Med Chem 38: 4157-60 (1995) BindingDB Entry DOI: 10.7270/Q21V5D0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052358 (3-(Biphenyl-4-yloxymethyl)-1-aza-bicyclo[2.2.2]oct...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052351 (3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052351 (3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]octan-3-ol | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Compound was measured for the inhibition of rat microsomal squalene synthase enzyme | J Med Chem 42: 1306-11 (1999) Article DOI: 10.1021/jm990038q BindingDB Entry DOI: 10.7270/Q23X85TQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052352 (3-Biphenyl-4-yl-1-aza-bicyclo[2.2.2]oct-2-ene | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052366 (3-(4'-Fluoro-biphenyl-4-yl)-1-aza-bicyclo[2.2.2]oc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50010960 ((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034750 ((E)-7-(4-{4-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50288601 ((Z)-6-[(2S,4S,5R)-2-(4-Cyano-phenyl)-4-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for thromboxane TXA2 synthase inhibitory activity using human platelet | Bioorg Med Chem Lett 6: 273-278 (1996) Article DOI: 10.1016/0960-894X(96)00004-2 BindingDB Entry DOI: 10.7270/Q2PG1RR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052367 (3-(Biphenyl-4-ylsulfanyl)-1-aza-bicyclo[2.2.2]octa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052357 (3-Biphenyl-4-ylmethyl-1-aza-bicyclo[2.2.2]octane |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034745 (3-(2-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052341 (3-(4-Pyrimidin-2-yl-phenyl)-1-aza-bicyclo[2.2.2]oc...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034769 ((E)-7-(4-{1-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034763 ((E)-7-(4-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034761 ((E)-7-[4-(2-{2-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034759 (3-(2-{3-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-enyl)-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50034751 ((E)-7-(4-{5-[(2S,4S,5R)-5-((Z)-5-Carboxy-pent-2-en...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against human microsomal thromboxane synthase. | J Med Chem 38: 1608-28 (1995) BindingDB Entry DOI: 10.7270/Q2319TWW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Squalene synthase (Rattus norvegicus) | BDBM50052372 (3-(4-Thiazol-2-yl-phenyl)-1-aza-bicyclo[2.2.2]octa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition against rat microsomal squalene synthase (SS) | J Med Chem 39: 2971-9 (1996) Article DOI: 10.1021/jm950907l BindingDB Entry DOI: 10.7270/Q24J0D7G | |||||||||||
More data for this Ligand-Target Pair |
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