Compile Data Set for Download or QSAR

Found 66 hits with Last Name = 'lamontagne' and Initial = 'kr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338221 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2cccc(F)c2)c(Cl)c1 Show InChI InChI=1S/C19H16ClFN6O3/c1-29-25-9-14-17(22)23-10-24-18(14)30-13-5-6-16(15(20)8-13)27-19(28)26-12-4-2-3-11(21)7-12/h2-10H,1H3,(H2,22,23,24)(H2,26,27,28)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338214 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2nc(C)c(C)s2)c(Cl)c1 Show InChI InChI=1S/C18H18ClN7O3S/c1-9-10(2)30-18(24-9)26-17(27)25-14-5-4-11(6-13(14)19)29-16-12(7-23-28-3)15(20)21-8-22-16/h4-8H,1-3H3,(H2,20,21,22)(H2,24,25,26,27)/b23-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338215 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2cc(C)on2)c(Cl)c1 Show InChI InChI=1S/C17H16ClN7O4/c1-9-5-14(25-29-9)24-17(26)23-13-4-3-10(6-12(13)18)28-16-11(7-22-27-2)15(19)20-8-21-16/h3-8H,1-2H3,(H2,19,20,21)(H2,23,24,25,26)/b22-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338219 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2OC)c(Cl)c1 Show InChI InChI=1S/C20H19ClN6O4/c1-29-17-6-4-3-5-16(17)27-20(28)26-15-8-7-12(9-14(15)21)31-19-13(10-25-30-2)18(22)23-11-24-19/h3-11H,1-2H3,(H2,22,23,24)(H2,26,27,28)/b25-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338217 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2Cl)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N6O3/c1-29-25-9-12-17(22)23-10-24-18(12)30-11-6-7-16(14(21)8-11)27-19(28)26-15-5-3-2-4-13(15)20/h2-10H,1H3,(H2,22,23,24)(H2,26,27,28)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338222 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccc(F)cc2)c(Cl)c1 Show InChI InChI=1S/C19H16ClFN6O3/c1-29-25-9-14-17(22)23-10-24-18(14)30-13-6-7-16(15(20)8-13)27-19(28)26-12-4-2-11(21)3-5-12/h2-10H,1H3,(H2,22,23,24)(H2,26,27,28)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338223 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccc(F)cc2F)c(Cl)c1 Show InChI InChI=1S/C19H15ClF2N6O3/c1-30-26-8-12-17(23)24-9-25-18(12)31-11-3-5-15(13(20)7-11)27-19(29)28-16-4-2-10(21)6-14(16)22/h2-9H,1H3,(H2,23,24,25)(H2,27,28,29)/b26-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338216 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2)c(Cl)c1 Show InChI InChI=1S/C19H17ClN6O3/c1-28-24-10-14-17(21)22-11-23-18(14)29-13-7-8-16(15(20)9-13)26-19(27)25-12-5-3-2-4-6-12/h2-11H,1H3,(H2,21,22,23)(H2,25,26,27)/b24-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338220 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2F)c(Cl)c1 Show InChI InChI=1S/C19H16ClFN6O3/c1-29-25-9-12-17(22)23-10-24-18(12)30-11-6-7-15(13(20)8-11)26-19(28)27-16-5-3-2-4-14(16)21/h2-10H,1H3,(H2,22,23,24)(H2,26,27,28)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338213 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2nccs2)c(Cl)c1 Show InChI InChI=1S/C16H14ClN7O3S/c1-26-22-7-10-13(18)20-8-21-14(10)27-9-2-3-12(11(17)6-9)23-15(25)24-16-19-4-5-28-16/h2-8H,1H3,(H2,18,20,21)(H2,19,23,24,25)/b22-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338225 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NC2CCCCC2)c(Cl)c1 Show InChI InChI=1S/C19H23ClN6O3/c1-28-24-10-14-17(21)22-11-23-18(14)29-13-7-8-16(15(20)9-13)26-19(27)25-12-5-3-2-4-6-12/h7-12H,2-6H2,1H3,(H2,21,22,23)(H2,25,26,27)/b24-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338218 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2C)c(Cl)c1 Show InChI InChI=1S/C20H19ClN6O3/c1-12-5-3-4-6-16(12)26-20(28)27-17-8-7-13(9-15(17)21)30-19-14(10-25-29-2)18(22)23-11-24-19/h3-11H,1-2H3,(H2,22,23,24)(H2,26,27,28)/b25-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338224 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCc2ccc(F)cc2F)c(Cl)c1 Show InChI InChI=1S/C20H17ClF2N6O3/c1-31-28-9-14-18(24)26-10-27-19(14)32-13-4-5-17(15(21)7-13)29-20(30)25-8-11-2-3-12(22)6-16(11)23/h2-7,9-10H,8H2,1H3,(H2,24,26,27)(H2,25,29,30)/b28-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338211 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2cccnc2)c(Cl)c1 Show InChI InChI=1S/C18H16ClN7O3/c1-28-24-9-13-16(20)22-10-23-17(13)29-12-4-5-15(14(19)7-12)26-18(27)25-11-3-2-6-21-8-11/h2-10H,1H3,(H2,20,22,23)(H2,25,26,27)/b24-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338212 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccncc2)c(Cl)c1 Show InChI InChI=1S/C18H16ClN7O3/c1-28-24-9-13-16(20)22-10-23-17(13)29-12-2-3-15(14(19)8-12)26-18(27)25-11-4-6-21-7-5-11/h2-10H,1H3,(H2,20,22,23)(H2,21,25,26,27)/b24-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338201 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12340 (3-{[(E)-({4-amino-6-[(4-fluoro-2-methyl-1H-indol-5...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCCCO)ccc2[nH]1 Show InChI InChI=1S/C17H18FN5O3/c1-10-7-11-13(23-10)3-4-14(15(11)18)26-17-12(16(19)20-9-21-17)8-22-25-6-2-5-24/h3-4,7-9,23-24H,2,5-6H2,1H3,(H2,19,20,21)/b22-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12336 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...) Show SMILES COCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C17H18FN5O3/c1-10-7-11-13(23-10)3-4-14(15(11)18)26-17-12(16(19)20-9-21-17)8-22-25-6-5-24-2/h3-4,7-9,23H,5-6H2,1-2H3,(H2,19,20,21)/b22-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338202 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl Show InChI InChI=1S/C14H15ClN6O3/c1-17-14(22)21-11-4-3-8(5-10(11)15)24-13-9(6-20-23-2)12(16)18-7-19-13/h3-7H,1-2H3,(H2,16,18,19)(H2,17,21,22)/b20-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338203 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CCCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl Show InChI InChI=1S/C16H19ClN6O3/c1-3-6-19-16(24)23-13-5-4-10(7-12(13)17)26-15-11(8-22-25-2)14(18)20-9-21-15/h4-5,7-9H,3,6H2,1-2H3,(H2,18,20,21)(H2,19,23,24)/b22-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338205 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NC2CC2)c(Cl)c1 Show InChI InChI=1S/C16H17ClN6O3/c1-25-21-7-11-14(18)19-8-20-15(11)26-10-4-5-13(12(17)6-10)23-16(24)22-9-2-3-9/h4-9H,2-3H2,1H3,(H2,18,19,20)(H2,22,23,24)/b21-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12338 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3CN=O)ccc2[nH]1 Show InChI InChI=1S/C14H12FN5O2/c1-7-4-8-10(20-7)2-3-11(12(8)15)22-14-9(5-19-21)13(16)17-6-18-14/h2-4,6,20H,5H2,1H3,(H2,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338210 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccn2)c(Cl)c1 Show InChI InChI=1S/C18H16ClN7O3/c1-28-24-9-12-16(20)22-10-23-17(12)29-11-5-6-14(13(19)8-11)25-18(27)26-15-4-2-3-7-21-15/h2-10H,1H3,(H2,20,22,23)(H2,21,25,26,27)/b24-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12334 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCCN3CCOCC3)ccc2[nH]1 Show InChI InChI=1S/C20H23FN6O3/c1-13-10-14-16(26-13)2-3-17(18(14)21)30-20-15(19(22)23-12-24-20)11-25-29-9-6-27-4-7-28-8-5-27/h2-3,10-12,26H,4-9H2,1H3,(H2,22,23,24)/b25-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12324 (5-[(1E)-(ethoxyimino)methyl]-6-[(4-fluoro-2-methyl...) Show SMILES CCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C16H16FN5O2/c1-3-23-21-7-11-15(18)19-8-20-16(11)24-13-5-4-12-10(14(13)17)6-9(2)22-12/h4-8,22H,3H2,1-2H3,(H2,18,19,20)/b21-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12325 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-(...) Show SMILES CCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C17H18FN5O2/c1-3-6-24-22-8-12-16(19)20-9-21-17(12)25-14-5-4-13-11(15(14)18)7-10(2)23-13/h4-5,7-9,23H,3,6H2,1-2H3,(H2,19,20,21)/b22-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12339 (2-{[(E)-({4-amino-6-[(4-fluoro-2-methyl-1H-indol-5...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCCO)ccc2[nH]1 Show InChI InChI=1S/C16H16FN5O3/c1-9-6-10-12(22-9)2-3-13(14(10)17)25-16-11(7-21-24-5-4-23)15(18)19-8-20-16/h2-3,6-8,22-23H,4-5H2,1H3,(H2,18,19,20)/b21-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12328 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCC#C)ccc2[nH]1 Show InChI InChI=1S/C17H14FN5O2/c1-3-6-24-22-8-12-16(19)20-9-21-17(12)25-14-5-4-13-11(15(14)18)7-10(2)23-13/h1,4-5,7-9,23H,6H2,2H3,(H2,19,20,21)/b22-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12327 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCC=C)ccc2[nH]1 Show InChI InChI=1S/C17H16FN5O2/c1-3-6-24-22-8-12-16(19)20-9-21-17(12)25-14-5-4-13-11(15(14)18)7-10(2)23-13/h3-5,7-9,23H,1,6H2,2H3,(H2,19,20,21)/b22-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12337 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-[...) Show SMILES COCCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C18H20FN5O3/c1-11-8-12-14(24-11)4-5-15(16(12)19)27-18-13(17(20)21-10-22-18)9-23-26-7-3-6-25-2/h4-5,8-10,24H,3,6-7H2,1-2H3,(H2,20,21,22)/b23-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338204 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NC(C)C)c(Cl)c1 Show InChI InChI=1S/C16H19ClN6O3/c1-9(2)22-16(24)23-13-5-4-10(6-12(13)17)26-15-11(7-21-25-3)14(18)19-8-20-15/h4-9H,1-3H3,(H2,18,19,20)(H2,22,23,24)/b21-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12331 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...) Show SMILES CNCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C17H19FN6O2/c1-10-7-11-13(24-10)3-4-14(15(11)18)26-17-12(16(19)21-9-22-17)8-23-25-6-5-20-2/h3-4,7-9,20,24H,5-6H2,1-2H3,(H2,19,21,22)/b23-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12335 (5-[(1E)-{[3-(dimethylamino)propoxy]imino}methyl]-6...) Show SMILES CN(C)CCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C19H23FN6O2/c1-12-9-13-15(25-12)5-6-16(17(13)20)28-19-14(18(21)22-11-23-19)10-24-27-8-4-7-26(2)3/h5-6,9-11,25H,4,7-8H2,1-3H3,(H2,21,22,23)/b24-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12326 (5-[(1E)-(butoxyimino)methyl]-6-[(4-fluoro-2-methyl...) Show SMILES CCCCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C18H20FN5O2/c1-3-4-7-25-23-9-13-17(20)21-10-22-18(13)26-15-6-5-14-12(16(15)19)8-11(2)24-14/h5-6,8-10,24H,3-4,7H2,1-2H3,(H2,20,21,22)/b23-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12322 (6-[(4-fluoro-1H-indol-5-yl)oxy]-5-[(1E)-(methoxyim...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc2[nH]ccc2c1F Show InChI InChI=1S/C14H12FN5O2/c1-21-20-6-9-13(16)18-7-19-14(9)22-11-3-2-10-8(12(11)15)4-5-17-10/h2-7,17H,1H3,(H2,16,18,19)/b20-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12323 (6-[(6-fluoro-1H-indol-5-yl)oxy]-5-[(1E)-(methoxyim...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1cc2cc[nH]c2cc1F Show InChI InChI=1S/C14H12FN5O2/c1-21-20-6-9-13(16)18-7-19-14(9)22-12-4-8-2-3-17-11(8)5-10(12)15/h2-7,17H,1H3,(H2,16,18,19)/b20-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338234 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1 Show InChI InChI=1S/C15H18N6O3/c1-3-17-15(22)21-10-4-6-11(7-5-10)24-14-12(8-20-23-2)13(16)18-9-19-14/h4-9H,3H2,1-2H3,(H2,16,18,19)(H2,17,21,22)/b20-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338231 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)c(F)c1 Show InChI InChI=1S/C14H15FN6O3/c1-17-14(22)21-8-3-4-11(10(15)5-8)24-13-9(6-20-23-2)12(16)18-7-19-13/h3-7H,1-2H3,(H2,16,18,19)(H2,17,21,22)/b20-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12320 (5-[(1E)-(methoxyimino)methyl]-6-[(2-methyl-1H-indo...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1 Show InChI InChI=1S/C15H15N5O2/c1-9-5-10-6-11(3-4-13(10)20-9)22-15-12(7-19-21-2)14(16)17-8-18-15/h3-8,20H,1-2H3,(H2,16,17,18)/b19-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	146	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338228 (CHEMBL1681958 | methyl 4-(6-amino-5-((methoxyimino...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)OC)cc1Cl Show InChI InChI=1S/C14H14ClN5O4/c1-22-14(21)20-8-3-4-11(10(15)5-8)24-13-9(6-19-23-2)12(16)17-7-18-13/h3-7H,1-2H3,(H,20,21)(H2,16,17,18)/b19-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338206 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCCO)c(Cl)c1 Show InChI InChI=1S/C15H17ClN6O4/c1-25-21-7-10-13(17)19-8-20-14(10)26-9-2-3-12(11(16)6-9)22-15(24)18-4-5-23/h2-3,6-8,23H,4-5H2,1H3,(H2,17,19,20)(H2,18,22,24)/b21-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338232 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)c(C)c1 Show InChI InChI=1S/C16H20N6O3/c1-4-18-16(23)22-11-5-6-13(10(2)7-11)25-15-12(8-21-24-3)14(17)19-9-20-15/h5-9H,4H2,1-3H3,(H2,17,19,20)(H2,18,22,23)/b21-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50338201 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl Show InChI InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of RET				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12332 (5-[(1E)-{[2-(dimethylamino)ethoxy]imino}methyl]-6-...) Show SMILES CN(C)CCO\N=C\c1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F Show InChI InChI=1S/C18H21FN6O2/c1-11-8-12-14(24-11)4-5-15(16(12)19)27-18-13(17(20)21-10-22-18)9-23-26-7-6-25(2)3/h4-5,8-10,24H,6-7H2,1-3H3,(H2,20,21,22)/b23-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12330 (5-[(1E)-[(benzyloxy)imino]methyl]-6-[(4-fluoro-2-m...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCc3ccccc3)ccc2[nH]1 Show InChI InChI=1S/C21H18FN5O2/c1-13-9-15-17(27-13)7-8-18(19(15)22)29-21-16(20(23)24-12-25-21)10-26-28-11-14-5-3-2-4-6-14/h2-10,12,27H,11H2,1H3,(H2,23,24,25)/b26-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	201	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12333 (6-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-[(1E)-{...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCCN3CCCC3)ccc2[nH]1 Show InChI InChI=1S/C20H23FN6O2/c1-13-10-14-16(26-13)4-5-17(18(14)21)29-20-15(19(22)23-12-24-20)11-25-28-9-8-27-6-2-3-7-27/h4-5,10-12,26H,2-3,6-9H2,1H3,(H2,22,23,24)/b25-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12318 (6-(1H-indol-5-yloxy)-5-[(1E)-(methoxyimino)methyl]...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc2[nH]ccc2c1 Show InChI InChI=1S/C14H13N5O2/c1-20-19-7-11-13(15)17-8-18-14(11)21-10-2-3-12-9(6-10)4-5-16-12/h2-8,16H,1H3,(H2,15,17,18)/b19-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	276	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338208 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCCN(C)C)c(Cl)c1 Show InChI InChI=1S/C17H22ClN7O3/c1-25(2)7-6-20-17(26)24-14-5-4-11(8-13(14)18)28-16-12(9-23-27-3)15(19)21-10-22-16/h4-5,8-10H,6-7H2,1-3H3,(H2,19,21,22)(H2,20,24,26)/b23-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338207 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)NCCCO)c(Cl)c1 Show InChI InChI=1S/C16H19ClN6O4/c1-26-22-8-11-14(18)20-9-21-15(11)27-10-3-4-13(12(17)7-10)23-16(25)19-5-2-6-24/h3-4,7-9,24H,2,5-6H2,1H3,(H2,18,20,21)(H2,19,23,25)/b22-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM12329 (5-[(1E)-[(cyclohexylmethoxy)imino]methyl]-6-[(4-fl...) Show SMILES Cc1cc2c(F)c(Oc3ncnc(N)c3\C=N\OCC3CCCCC3)ccc2[nH]1 Show InChI InChI=1S/C21H24FN5O2/c1-13-9-15-17(27-13)7-8-18(19(15)22)29-21-16(20(23)24-12-25-21)10-26-28-11-14-5-3-2-4-6-14/h7-10,12,14,27H,2-6,11H2,1H3,(H2,23,24,25)/b26-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	413	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				Bioorg Med Chem Lett 16: 6063-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.107 BindingDB Entry DOI: 10.7270/Q28P5XRX
					More data for this Ligand-Target Pair

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