Compile Data Set for Download or QSAR

Found 1695 hits with Last Name = 'perrey' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM116986 (US8637532, 713) Show SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2ccc(F)c(O)c2)c1 |r| Show InChI InChI=1S/C24H20FN5O3/c1-13(29-23-18-7-3-6-17(22(26)32)21(18)27-12-28-23)14-4-2-5-16(10-14)30-24(33)15-8-9-19(25)20(31)11-15/h2-13,31H,1H3,(H2,26,32)(H,30,33)(H,27,28,29)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210476 ((2,5-difluorobenzyl)-{4-[7-dimethylaminomethyl-2-(...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2cc(F)ccc2F)n1 Show InChI InChI=1S/C27H23F3N6/c1-35(2)16-17-10-12-36-24(13-17)34-25(18-3-5-20(28)6-4-18)26(36)23-9-11-31-27(33-23)32-15-19-14-21(29)7-8-22(19)30/h3-14H,15-16H2,1-2H3,(H,31,32,33)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0260	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116576 (US8637532, 268) Show SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2cc(n[nH]2)C(C)(C)C)c1 |r| Show InChI InChI=1S/C25H27N7O2/c1-14(29-23-18-10-6-9-17(22(26)33)21(18)27-13-28-23)15-7-5-8-16(11-15)30-24(34)19-12-20(32-31-19)25(2,3)4/h5-14H,1-4H3,(H2,26,33)(H,30,34)(H,31,32)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116550 (US8637532, 241) Show SMILES CC(C)c1cc([nH]n1)C(=O)Nc1cccc(c1)[C@@H](C)Nc1ncnc2c(cccc12)C(N)=O |r| Show InChI InChI=1S/C24H25N7O2/c1-13(2)19-11-20(31-30-19)24(33)29-16-7-4-6-15(10-16)14(3)28-23-18-9-5-8-17(22(25)32)21(18)26-12-27-23/h4-14H,1-3H3,(H2,25,32)(H,29,33)(H,30,31)(H,26,27,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116811 (US8637532, 537) Show SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)C2CC2(F)F)c1 |r| Show InChI InChI=1S/C21H19F2N5O2/c1-11(12-4-2-5-13(8-12)28-20(30)16-9-21(16,22)23)27-19-15-7-3-6-14(18(24)29)17(15)25-10-26-19/h2-8,10-11,16H,9H2,1H3,(H2,24,29)(H,28,30)(H,25,26,27)/t11-,16?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116714 (US8637532, 423) Show SMILES COc1ccc(cn1)C(=O)Nc1cccc(CNc2ncnc3c(cccc23)C(N)=O)c1 Show InChI InChI=1S/C23H20N6O3/c1-32-19-9-8-15(12-25-19)23(31)29-16-5-2-4-14(10-16)11-26-22-18-7-3-6-17(21(24)30)20(18)27-13-28-22/h2-10,12-13H,11H2,1H3,(H2,24,30)(H,29,31)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265424 (2-{4-[3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CCO)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H25FN6O/c25-19-3-1-17(2-4-19)22-23(20-5-9-27-24(26)28-20)31-12-8-18(15-21(31)29-22)16-6-10-30(11-7-16)13-14-32/h1-5,8-9,12,15-16,32H,6-7,10-11,13-14H2,(H2,26,27,28)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0440	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50182369 (4-(2-(4-fluorophenyl)-7-(1-methylpiperidin-4-yl)H-...) Show SMILES CN1CCC(CC1)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C23H23FN6/c1-29-11-7-15(8-12-29)17-9-13-30-20(14-17)28-21(16-2-4-18(24)5-3-16)22(30)19-6-10-26-23(25)27-19/h2-6,9-10,13-15H,7-8,11-12H2,1H3,(H2,25,26,27)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0440	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116779 (US8637532, 496) Show SMILES NC(=O)c1cccc2c(NCc3ccc(NC(=O)c4cc(n[nH]4)C(F)(F)F)cc3)ncnc12 Show InChI InChI=1S/C21H16F3N7O2/c22-21(23,24)16-8-15(30-31-16)20(33)29-12-6-4-11(5-7-12)9-26-19-14-3-1-2-13(18(25)32)17(14)27-10-28-19/h1-8,10H,9H2,(H2,25,32)(H,29,33)(H,30,31)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50182367 (4-(2-(4-fluorophenyl)-7-(piperidin-4-yl)H-imidazo[...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCNCC1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN6/c23-17-3-1-15(2-4-17)20-21(18-7-11-26-22(24)27-18)29-12-8-16(13-19(29)28-20)14-5-9-25-10-6-14/h1-4,7-8,11-14,25H,5-6,9-10H2,(H2,24,26,27)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116717 (US8637532, 426) Show SMILES CCN(CC)c1ccc(cc1)C(=O)Nc1cccc(c1)C(C)Nc1ncnc2c(cccc12)C(N)=O Show InChI InChI=1S/C28H30N6O2/c1-4-34(5-2)22-14-12-19(13-15-22)28(36)33-21-9-6-8-20(16-21)18(3)32-27-24-11-7-10-23(26(29)35)25(24)30-17-31-27/h6-18H,4-5H2,1-3H3,(H2,29,35)(H,33,36)(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0460	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116749 (US8637532, 462) Show SMILES COCCC(Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2ccc(OC(F)(F)F)cc2)c1 Show InChI InChI=1S/C27H24F3N5O4/c1-38-13-12-22(35-25-21-7-3-6-20(24(31)36)23(21)32-15-33-25)17-4-2-5-18(14-17)34-26(37)16-8-10-19(11-9-16)39-27(28,29)30/h2-11,14-15,22H,12-13H2,1H3,(H2,31,36)(H,34,37)(H,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116622 (US8637532, 319) Show SMILES COCCC(Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2ccc(Br)cc2)c1 Show InChI InChI=1S/C26H24BrN5O3/c1-35-13-12-22(32-25-21-7-3-6-20(24(28)33)23(21)29-15-30-25)17-4-2-5-19(14-17)31-26(34)16-8-10-18(27)11-9-16/h2-11,14-15,22H,12-13H2,1H3,(H2,28,33)(H,31,34)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210490 ((2-chlorobenzyl)-{4-[7-dimethylaminomethyl-2-(4-fl...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2Cl)n1 Show InChI InChI=1S/C27H24ClFN6/c1-34(2)17-18-12-14-35-24(15-18)33-25(19-7-9-21(29)10-8-19)26(35)23-11-13-30-27(32-23)31-16-20-5-3-4-6-22(20)28/h3-15H,16-17H2,1-2H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0560	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210479 ((2,6-difluorobenzyl)-{4-[7-dimethylaminomethyl-2-(...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2c(F)cccc2F)n1 Show InChI InChI=1S/C27H23F3N6/c1-35(2)16-17-11-13-36-24(14-17)34-25(18-6-8-19(28)9-7-18)26(36)23-10-12-31-27(33-23)32-15-20-21(29)4-3-5-22(20)30/h3-14H,15-16H2,1-2H3,(H,31,32,33)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116823 (US8637532, 549) Show SMILES NC(=O)c1cccc2c(NCc3cccc(Nc4cc(ccn4)C#N)c3)ncnc12 Show InChI InChI=1S/C22H17N7O/c23-11-14-7-8-25-19(10-14)29-16-4-1-3-15(9-16)12-26-22-18-6-2-5-17(21(24)30)20(18)27-13-28-22/h1-10,13H,12H2,(H2,24,30)(H,25,29)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116690 (US8637532, 394) Show SMILES CC(C)c1cc([nH]n1)C(=O)Nc1cccc(c1)C(C)Nc1ncnc2c(cccc12)C(N)=O Show InChI InChI=1S/C24H25N7O2/c1-13(2)19-11-20(31-30-19)24(33)29-16-7-4-6-15(10-16)14(3)28-23-18-9-5-8-17(22(25)32)21(18)26-12-27-23/h4-14H,1-3H3,(H2,25,32)(H,29,33)(H,30,31)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210473 ((3,4-difluorobenzyl)-{4-[7-dimethylaminomethyl-2-(...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccc(F)c(F)c2)n1 Show InChI InChI=1S/C27H23F3N6/c1-35(2)16-18-10-12-36-24(14-18)34-25(19-4-6-20(28)7-5-19)26(36)23-9-11-31-27(33-23)32-15-17-3-8-21(29)22(30)13-17/h3-14H,15-16H2,1-2H3,(H,31,32,33)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116931 (US8637532, 658) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc5OC(F)(F)Oc5c4)c3)ncnc12 Show InChI InChI=1S/C24H17F2N5O4/c25-24(26)34-18-8-7-14(10-19(18)35-24)23(33)31-15-4-1-3-13(9-15)11-28-22-17-6-2-5-16(21(27)32)20(17)29-12-30-22/h1-10,12H,11H2,(H2,27,32)(H,31,33)(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116925 (US8637532, 652) Show SMILES COCCOc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(=O)c4ccc(OC)cc4)c3)c2c1 Show InChI InChI=1S/C27H27N5O5/c1-35-10-11-37-21-13-22(25(28)33)24-23(14-21)26(31-16-30-24)29-15-17-4-3-5-19(12-17)32-27(34)18-6-8-20(36-2)9-7-18/h3-9,12-14,16H,10-11,15H2,1-2H3,(H2,28,33)(H,32,34)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116924 (US8637532, 651) Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(CNc2ncnc3c(cccc23)C(N)=O)c1 Show InChI InChI=1S/C24H21N5O2/c1-15-5-2-7-17(11-15)24(31)29-18-8-3-6-16(12-18)13-26-23-20-10-4-9-19(22(25)30)21(20)27-14-28-23/h2-12,14H,13H2,1H3,(H2,25,30)(H,29,31)(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0610	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210495 (CHEMBL251184 | cyclopropylmethyl{4-[7-dimethylamin...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC2CC2)n1 Show InChI InChI=1S/C24H25FN6/c1-30(2)15-17-10-12-31-21(13-17)29-22(18-5-7-19(25)8-6-18)23(31)20-9-11-26-24(28-20)27-14-16-3-4-16/h5-13,16H,3-4,14-15H2,1-2H3,(H,26,27,28)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0640	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265425 (2-{4-[3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CCCO)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H27FN6O/c26-20-4-2-18(3-5-20)23-24(21-6-10-28-25(27)29-21)32-14-9-19(16-22(32)30-23)17-7-12-31(13-8-17)11-1-15-33/h2-6,9-10,14,16-17,33H,1,7-8,11-13,15H2,(H2,27,28,29)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265419 (4-[7-(1-Dimethylaminobutyl)-2-(4-fluorophenyl)imid...) Show SMILES CCCC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C23H25FN6/c1-4-5-19(29(2)3)16-11-13-30-20(14-16)28-21(15-6-8-17(24)9-7-15)22(30)18-10-12-26-23(25)27-18/h6-14,19H,4-5H2,1-3H3,(H2,25,26,27)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210517 (CHEMBL249527 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccc(F)cc2)n1 Show InChI InChI=1S/C27H24F2N6/c1-34(2)17-19-12-14-35-24(15-19)33-25(20-5-9-22(29)10-6-20)26(35)23-11-13-30-27(32-23)31-16-18-3-7-21(28)8-4-18/h3-15H,16-17H2,1-2H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0660	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265397 (4-[7-(1-Dimethylaminoethyl)-2-(4-fluorophenyl)imid...) Show SMILES CC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C21H21FN6/c1-13(27(2)3)15-9-11-28-18(12-15)26-19(14-4-6-16(22)7-5-14)20(28)17-8-10-24-21(23)25-17/h4-13H,1-3H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0670	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265397 (4-[7-(1-Dimethylaminoethyl)-2-(4-fluorophenyl)imid...) Show SMILES CC(N(C)C)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C21H21FN6/c1-13(27(2)3)15-9-11-28-18(12-15)26-19(14-4-6-16(22)7-5-14)20(28)17-8-10-24-21(23)25-17/h4-13H,1-3H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0670	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265430 (4-[2-(4-Fluorophenyl)-7-(1-phenethylpiperidin-4-yl...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CCc2ccccc2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C30H29FN6/c31-25-8-6-23(7-9-25)28-29(26-10-15-33-30(32)34-26)37-19-14-24(20-27(37)35-28)22-12-17-36(18-13-22)16-11-21-4-2-1-3-5-21/h1-10,14-15,19-20,22H,11-13,16-18H2,(H2,32,33,34)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116623 (US8637532, 320) Show SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2ccc(nc2)C(F)(F)F)c1 |r| Show InChI InChI=1S/C24H19F3N6O2/c1-13(32-22-18-7-3-6-17(21(28)34)20(18)30-12-31-22)14-4-2-5-16(10-14)33-23(35)15-8-9-19(29-11-15)24(25,26)27/h2-13H,1H3,(H2,28,34)(H,33,35)(H,30,31,32)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116548 (US8637532, 239) Show SMILES COc1ccc(cn1)C(=O)Nc1cccc(c1)[C@@H](C)Nc1ncnc2c(cccc12)C(N)=O |r| Show InChI InChI=1S/C24H22N6O3/c1-14(29-23-19-8-4-7-18(22(25)31)21(19)27-13-28-23)15-5-3-6-17(11-15)30-24(32)16-9-10-20(33-2)26-12-16/h3-14H,1-2H3,(H2,25,31)(H,30,32)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116938 (US8637532, 665) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)C4=CCC(C=C4)N4CCOCC4)c3)ncnc12 |c:23,t:19| Show InChI InChI=1S/C27H28N6O3/c28-25(34)22-5-2-6-23-24(22)30-17-31-26(23)29-16-18-3-1-4-20(15-18)32-27(35)19-7-9-21(10-8-19)33-11-13-36-14-12-33/h1-9,15,17,21H,10-14,16H2,(H2,28,34)(H,32,35)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116579 (US8637532, 271) Show SMILES CC(Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)c2cc(n[nH]2)C(C)(C)C)c1 Show InChI InChI=1S/C25H27N7O2/c1-14(29-23-18-10-6-9-17(22(26)33)21(18)27-13-28-23)15-7-5-8-16(11-15)30-24(34)19-12-20(32-31-19)25(2,3)4/h5-14H,1-4H3,(H2,26,33)(H,30,34)(H,31,32)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116987 (US8637532, 714) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4c(F)cc(Cl)cc4F)c3)ncnc12 Show InChI InChI=1S/C23H16ClF2N5O2/c24-13-8-17(25)19(18(26)9-13)23(33)31-14-4-1-3-12(7-14)10-28-22-16-6-2-5-15(21(27)32)20(16)29-11-30-22/h1-9,11H,10H2,(H2,27,32)(H,31,33)(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210494 (CHEMBL250601 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2C)n1 Show InChI InChI=1S/C28H27FN6/c1-19-6-4-5-7-22(19)17-31-28-30-14-12-24(32-28)27-26(21-8-10-23(29)11-9-21)33-25-16-20(18-34(2)3)13-15-35(25)27/h4-16H,17-18H2,1-3H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210508 (CHEMBL250791 | cyclopropyl{4-[7-dimethylaminomethy...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC2CC2)n1 Show InChI InChI=1S/C23H23FN6/c1-29(2)14-15-10-12-30-20(13-15)28-21(16-3-5-17(24)6-4-16)22(30)19-9-11-25-23(27-19)26-18-7-8-18/h3-6,9-13,18H,7-8,14H2,1-2H3,(H,25,26,27)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116652 (US8637532, 352) Show SMILES C[C@@H](Nc1ncnc2c(cccc12)C(N)=O)c1cccc(Nc2cc(ccn2)C#N)c1 |r| Show InChI InChI=1S/C23H19N7O/c1-14(29-23-19-7-3-6-18(22(25)31)21(19)27-13-28-23)16-4-2-5-17(11-16)30-20-10-15(12-24)8-9-26-20/h2-11,13-14H,1H3,(H2,25,31)(H,26,30)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116944 (US8637532, 671) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc(Cl)cc4)c3)ncnc12 Show InChI InChI=1S/C23H18ClN5O2/c24-16-9-7-15(8-10-16)23(31)29-17-4-1-3-14(11-17)12-26-22-19-6-2-5-18(21(25)30)20(19)27-13-28-22/h1-11,13H,12H2,(H2,25,30)(H,29,31)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116954 (US8637532, 681) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc(Cl)c(c4)C(F)(F)F)c3)ncnc12 Show InChI InChI=1S/C24H17ClF3N5O2/c25-19-8-7-14(10-18(19)24(26,27)28)23(35)33-15-4-1-3-13(9-15)11-30-22-17-6-2-5-16(21(29)34)20(17)31-12-32-22/h1-10,12H,11H2,(H2,29,34)(H,33,35)(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210489 (CHEMBL249526 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2cccc(C)c2)n1 Show InChI InChI=1S/C28H27FN6/c1-19-5-4-6-20(15-19)17-31-28-30-13-11-24(32-28)27-26(22-7-9-23(29)10-8-22)33-25-16-21(18-34(2)3)12-14-35(25)27/h4-16H,17-18H2,1-3H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0830	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210493 (CHEMBL401102 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2F)n1 Show InChI InChI=1S/C27H24F2N6/c1-34(2)17-18-12-14-35-24(15-18)33-25(19-7-9-21(28)10-8-19)26(35)23-11-13-30-27(32-23)31-16-20-5-3-4-6-22(20)29/h3-15H,16-17H2,1-2H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0870	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM116959 (US8637532, 686) Show SMILES NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4cc(n[nH]4)C4CC4)c3)ncnc12 Show InChI InChI=1S/C23H21N7O2/c24-21(31)16-5-2-6-17-20(16)26-12-27-22(17)25-11-13-3-1-4-15(9-13)28-23(32)19-10-18(29-30-19)14-7-8-14/h1-6,9-10,12,14H,7-8,11H2,(H2,24,31)(H,28,32)(H,29,30)(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0890	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210478 (CHEMBL249326 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2cccc(F)c2)n1 Show InChI InChI=1S/C27H24F2N6/c1-34(2)17-19-11-13-35-24(15-19)33-25(20-6-8-21(28)9-7-20)26(35)23-10-12-30-27(32-23)31-16-18-4-3-5-22(29)14-18/h3-15H,16-17H2,1-2H3,(H,30,31,32)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116747 (US8637532, 459) Show SMILES COCCN(C)c1ccc(cn1)C(=O)Nc1cccc(CNc2ncnc3c(cccc23)C(N)=O)c1 Show InChI InChI=1S/C26H27N7O3/c1-33(11-12-36-2)22-10-9-18(15-28-22)26(35)32-19-6-3-5-17(13-19)14-29-25-21-8-4-7-20(24(27)34)23(21)30-16-31-25/h3-10,13,15-16H,11-12,14H2,1-2H3,(H2,27,34)(H,32,35)(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116639 (US8637532, 338) Show SMILES COc1ccc(cc1)C(=O)Nc1cccc(c1)C(CCO)Nc1ncnc2c(cccc12)C(N)=O Show InChI InChI=1S/C26H25N5O4/c1-35-19-10-8-16(9-11-19)26(34)30-18-5-2-4-17(14-18)22(12-13-32)31-25-21-7-3-6-20(24(27)33)23(21)28-15-29-25/h2-11,14-15,22,32H,12-13H2,1H3,(H2,27,33)(H,30,34)(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116555 (US8637532, 246) Show SMILES CC(Nc1ncnc2c(cccc12)C(N)=O)c1cccc(NC(=O)C2=CCC(C)C(F)=C2)c1 |c:32,t:26| Show InChI InChI=1S/C25H24FN5O2/c1-14-9-10-17(12-21(14)26)25(33)31-18-6-3-5-16(11-18)15(2)30-24-20-8-4-7-19(23(27)32)22(20)28-13-29-24/h3-8,10-15H,9H2,1-2H3,(H2,27,32)(H,31,33)(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265427 (4-[7-(1-Cyclopropylmethylpiperidin-4-yl)-2-(4-fluo...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CC2CC2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H27FN6/c27-21-5-3-19(4-6-21)24-25(22-7-11-29-26(28)30-22)33-14-10-20(15-23(33)31-24)18-8-12-32(13-9-18)16-17-1-2-17/h3-7,10-11,14-15,17-18H,1-2,8-9,12-13,16H2,(H2,28,29,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210500 (CHEMBL251589 | {4-[7-dimethylaminomethyl-2-(4-fluo...) Show SMILES CCCCCNc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C25H29FN6/c1-4-5-6-13-27-25-28-14-11-21(29-25)24-23(19-7-9-20(26)10-8-19)30-22-16-18(17-31(2)3)12-15-32(22)24/h7-12,14-16H,4-6,13,17H2,1-3H3,(H,27,28,29)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50210511 (4-[2-(2,4-difluorophenyl)-7-dimethylaminomethylimi...) Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1F)-c1ccnc(N)n1 Show InChI InChI=1S/C20H18F2N6/c1-27(2)11-12-6-8-28-17(9-12)26-18(14-4-3-13(21)10-15(14)22)19(28)16-5-7-24-20(23)25-16/h3-10H,11H2,1-2H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay				Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116598 (US8637532, 292) Show SMILES COc1ccc(cn1)C(=O)Nc1cccc(c1)C(C)Nc1ncnc2c(cccc12)C(N)=O Show InChI InChI=1S/C24H22N6O3/c1-14(29-23-19-8-4-7-18(22(25)31)21(19)27-13-28-23)15-5-3-6-17(11-15)30-24(32)16-9-10-20(33-2)26-12-16/h3-14H,1-2H3,(H2,25,31)(H,30,32)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM116922 (US8637532, 649) Show SMILES Cc1ccccc1C(=O)Nc1cccc(CNc2ncnc3c(cccc23)C(N)=O)c1 Show InChI InChI=1S/C24H21N5O2/c1-15-6-2-3-9-18(15)24(31)29-17-8-4-7-16(12-17)13-26-23-20-11-5-10-19(22(25)30)21(20)27-14-28-23/h2-12,14H,13H2,1H3,(H2,25,30)(H,29,31)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Patent GmbH US Patent					Assay Description The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...				US Patent US8637532 (2014) BindingDB Entry DOI: 10.7270/Q21G0JZX
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1695 total )  |  Next  |  Last  >>

Jump to: