Found 447 hits with Last Name = 'stone' and Initial = 'r' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124714
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-4,...)Show SMILES CCCCN1[C@H](Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O Show InChI InChI=1S/C31H37N5O3/c1-2-3-16-35-26(18-21-10-6-4-7-11-21)28(37)29(38)27(19-22-12-8-5-9-13-22)36(31(35)39)20-23-14-15-25-24(17-23)30(32)34-33-25/h4-15,17,26-29,37-38H,2-3,16,18-20H2,1H3,(H3,32,33,34)/t26-,27-,28+,29+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 0.0210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124721
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3,...)Show SMILES Nc1[nH]nc2ccc(CN3[C@H](Cc4ccccc4)[C@H](O)[C@@H](O)[C@@H](Cc4ccccc4)N(Cc4ccccc4)C3=O)cc12 Show InChI InChI=1S/C34H35N5O3/c35-33-27-18-26(16-17-28(27)36-37-33)22-39-30(20-24-12-6-2-7-13-24)32(41)31(40)29(19-23-10-4-1-5-11-23)38(34(39)42)21-25-14-8-3-9-15-25/h1-18,29-32,40-41H,19-22H2,(H3,35,36,37)/t29-,30-,31+,32+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 0.0310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124716
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES CCCCN1[C@H](Cc2ccc(C)cc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccc(C)cc2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O Show InChI InChI=1S/C33H41N5O3/c1-4-5-16-37-28(18-23-10-6-21(2)7-11-23)30(39)31(40)29(19-24-12-8-22(3)9-13-24)38(33(37)41)20-25-14-15-27-26(17-25)32(34)36-35-27/h6-15,17,28-31,39-40H,4-5,16,18-20H2,1-3H3,(H3,34,35,36)/t28-,29-,30+,31+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124715
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES CCCCN1[C@H](Cc2cccc(C)c2)[C@H](O)[C@@H](O)[C@@H](Cc2cccc(C)c2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O Show InChI InChI=1S/C33H41N5O3/c1-4-5-14-37-28(18-23-10-6-8-21(2)15-23)30(39)31(40)29(19-24-11-7-9-22(3)16-24)38(33(37)41)20-25-12-13-27-26(17-25)32(34)36-35-27/h6-13,15-17,28-31,39-40H,4-5,14,18-20H2,1-3H3,(H3,34,35,36)/t28-,29-,30+,31+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124722
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES Cc1ccc(C[C@@H]2[C@H](O)[C@@H](O)[C@@H](Cc3ccc(C)cc3)N(Cc3ccc4[nH]nc(N)c4c3)C(=O)N2Cc2ccccc2)cc1 Show InChI InChI=1S/C36H39N5O3/c1-23-8-12-25(13-9-23)19-31-33(42)34(43)32(20-26-14-10-24(2)11-15-26)41(36(44)40(31)21-27-6-4-3-5-7-27)22-28-16-17-30-29(18-28)35(37)39-38-30/h3-18,31-34,42-43H,19-22H2,1-2H3,(H3,37,38,39)/t31-,32-,33+,34+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124718
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES Cc1cccc(C[C@@H]2[C@H](O)[C@@H](O)[C@@H](Cc3cccc(C)c3)N(Cc3ccc4[nH]nc(N)c4c3)C(=O)N2Cc2ccccc2)c1 Show InChI InChI=1S/C36H39N5O3/c1-23-8-6-12-26(16-23)19-31-33(42)34(43)32(20-27-13-7-9-24(2)17-27)41(36(44)40(31)21-25-10-4-3-5-11-25)22-28-14-15-30-29(18-28)35(37)39-38-30/h3-18,31-34,42-43H,19-22H2,1-2H3,(H3,37,38,39)/t31-,32-,33+,34+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124723
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES CCc1ccc(C[C@@H]2[C@H](O)[C@@H](O)[C@@H](Cc3ccc(CC)cc3)N(Cc3ccc4[nH]nc(N)c4c3)C(=O)N2Cc2ccccc2)cc1 Show InChI InChI=1S/C38H43N5O3/c1-3-25-10-14-27(15-11-25)21-33-35(44)36(45)34(22-28-16-12-26(4-2)13-17-28)43(38(46)42(33)23-29-8-6-5-7-9-29)24-30-18-19-32-31(20-30)37(39)41-40-32/h5-20,33-36,44-45H,3-4,21-24H2,1-2H3,(H3,39,40,41)/t33-,34-,35+,36+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124717
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES CCCCN1[C@H](Cc2ccc(CC)cc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccc(CC)cc2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O Show InChI InChI=1S/C35H45N5O3/c1-4-7-18-39-30(20-25-12-8-23(5-2)9-13-25)32(41)33(42)31(21-26-14-10-24(6-3)11-15-26)40(35(39)43)22-27-16-17-29-28(19-27)34(36)38-37-29/h8-17,19,30-33,41-42H,4-7,18,20-22H2,1-3H3,(H3,36,37,38)/t30-,31-,32+,33+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.0940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124719
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES CCCCN1[C@H](Cc2cc(C)cc(C)c2)[C@H](O)[C@@H](O)[C@@H](Cc2cc(C)cc(C)c2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O Show InChI InChI=1S/C35H45N5O3/c1-6-7-10-39-30(18-26-13-21(2)11-22(3)14-26)32(41)33(42)31(19-27-15-23(4)12-24(5)16-27)40(35(39)43)20-25-8-9-29-28(17-25)34(36)38-37-29/h8-9,11-17,30-33,41-42H,6-7,10,18-20H2,1-5H3,(H3,36,37,38)/t30-,31-,32+,33+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Gag-Pol polyprotein [489-587]
(Human immunodeficiency virus type 1) | BDBM50124720
((4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-...)Show SMILES Cc1cc(C)cc(C[C@@H]2[C@H](O)[C@@H](O)[C@@H](Cc3cc(C)cc(C)c3)N(Cc3ccc4[nH]nc(N)c4c3)C(=O)N2Cc2ccccc2)c1 Show InChI InChI=1S/C38H43N5O3/c1-23-12-24(2)15-29(14-23)19-33-35(44)36(45)34(20-30-16-25(3)13-26(4)17-30)43(38(46)42(33)21-27-8-6-5-7-9-27)22-28-10-11-32-31(18-28)37(39)41-40-32/h5-18,33-36,44-45H,19-22H2,1-4H3,(H3,39,40,41)/t33-,34-,35+,36+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description
Binding affinity of the compound against HIV-Protease was determined |
Bioorg Med Chem Lett 13: 605-8 (2003)
BindingDB Entry DOI: 10.7270/Q27D2THB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376255
(CHEMBL408401)Show InChI InChI=1S/C23H25N3O/c1-26(20-8-3-2-4-9-20)21-13-11-17(12-14-21)23(27)25-19-15-18-7-5-6-10-22(18)24-16-19/h5-7,10-16,20H,2-4,8-9H2,1H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376256
(CHEMBL259017)Show InChI InChI=1S/C25H31N3O/c1-3-4-5-6-7-10-17-28(2)23-15-13-20(14-16-23)25(29)27-22-18-21-11-8-9-12-24(21)26-19-22/h8-9,11-16,18-19H,3-7,10,17H2,1-2H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376268
(CHEMBL405387)Show SMILES CN(CC1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C24H27N3O/c1-27(17-18-7-3-2-4-8-18)22-13-11-19(12-14-22)24(28)26-21-15-20-9-5-6-10-23(20)25-16-21/h5-6,9-16,18H,2-4,7-8,17H2,1H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376272
(CHEMBL407233)Show SMILES CCCCCCCCCN(C)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C26H33N3O/c1-3-4-5-6-7-8-11-18-29(2)24-16-14-21(15-17-24)26(30)28-23-19-22-12-9-10-13-25(22)27-20-23/h9-10,12-17,19-20H,3-8,11,18H2,1-2H3,(H,28,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376273
(CHEMBL261766)Show InChI InChI=1S/C24H29N3O/c1-3-4-5-6-9-16-27(2)22-14-12-19(13-15-22)24(28)26-21-17-20-10-7-8-11-23(20)25-18-21/h7-8,10-15,17-18H,3-6,9,16H2,1-2H3,(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376277
(CHEMBL258917)Show InChI InChI=1S/C20H20N2O/c1-20(2,3)16-10-8-14(9-11-16)19(23)22-17-12-15-6-4-5-7-18(15)21-13-17/h4-13H,1-3H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273022
(1-(2,3-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)Show SMILES Cc1cccc(N2CCC(CC2)C(=O)Nc2ccc3OCC(=O)Nc3c2)c1C Show InChI InChI=1S/C22H25N3O3/c1-14-4-3-5-19(15(14)2)25-10-8-16(9-11-25)22(27)23-17-6-7-20-18(12-17)24-21(26)13-28-20/h3-7,12,16H,8-11,13H2,1-2H3,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376260
(CHEMBL259601)Show InChI InChI=1S/C21H21NO2/c1-2-3-5-15-8-10-17(11-9-15)21(24)22-20-7-4-6-16-12-13-18(23)14-19(16)20/h4,6-14,23H,2-3,5H2,1H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376275
(CHEMBL260356)Show InChI InChI=1S/C22H25N3O/c1-3-4-7-14-25(2)20-12-10-17(11-13-20)22(26)24-19-15-18-8-5-6-9-21(18)23-16-19/h5-6,8-13,15-16H,3-4,7,14H2,1-2H3,(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273058
(CHEMBL457186 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)Show SMILES Fc1cc(cc(F)c1F)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H18F3N3O3/c21-14-8-13(9-15(22)19(14)23)26-5-3-11(4-6-26)20(28)24-12-1-2-17-16(7-12)25-18(27)10-29-17/h1-2,7-9,11H,3-6,10H2,(H,24,28)(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376281
(CHEMBL259385)Show InChI InChI=1S/C20H20N2O/c1-2-3-6-15-9-11-16(12-10-15)20(23)22-18-13-17-7-4-5-8-19(17)21-14-18/h4-5,7-14H,2-3,6H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273024
(1-(3,4-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)Show SMILES Fc1ccc(cc1F)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H19F2N3O3/c21-15-3-2-14(10-16(15)22)25-7-5-12(6-8-25)20(27)23-13-1-4-18-17(9-13)24-19(26)11-28-18/h1-4,9-10,12H,5-8,11H2,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376280
(CHEMBL259600)Show InChI InChI=1S/C19H18N2O/c1-2-5-14-8-10-15(11-9-14)19(22)21-17-12-16-6-3-4-7-18(16)20-13-17/h3-4,6-13H,2,5H2,1H3,(H,21,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272980
(CHEMBL455958 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)Show SMILES Cc1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H23N3O3/c1-14-4-2-3-5-18(14)24-10-8-15(9-11-24)21(26)22-16-6-7-19-17(12-16)23-20(25)13-27-19/h2-7,12,15H,8-11,13H2,1H3,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 61 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272856
(CHEMBL497485 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)Show SMILES FC(F)(F)c1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H20F3N3O3/c22-21(23,24)14-2-1-3-16(10-14)27-8-6-13(7-9-27)20(29)25-15-4-5-18-17(11-15)26-19(28)12-30-18/h1-5,10-11,13H,6-9,12H2,(H,25,29)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272979
(CHEMBL509968 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)Show SMILES FC(F)(F)c1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H20F3N3O3/c22-21(23,24)15-3-1-2-4-17(15)27-9-7-13(8-10-27)20(29)25-14-5-6-18-16(11-14)26-19(28)12-30-18/h1-6,11,13H,7-10,12H2,(H,25,29)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376274
(CHEMBL408637)Show InChI InChI=1S/C23H27N3O/c1-3-4-5-8-15-26(2)21-13-11-18(12-14-21)23(27)25-20-16-19-9-6-7-10-22(19)24-17-20/h6-7,9-14,16-17H,3-5,8,15H2,1-2H3,(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272900
(1-(2-bromophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)Show SMILES Brc1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H20BrN3O3/c21-15-3-1-2-4-17(15)24-9-7-13(8-10-24)20(26)22-14-5-6-18-16(11-14)23-19(25)12-27-18/h1-6,11,13H,7-10,12H2,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376282
(CHEMBL407762)Show InChI InChI=1S/C20H20N2O/c1-2-3-5-15-8-10-16(11-9-15)20(23)22-19-7-4-6-17-14-21-13-12-18(17)19/h4,6-14H,2-3,5H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272982
(1-(2-isopropylphenyl)-N-(3-oxo-3,4-dihydro-2H-benz...)Show SMILES CC(C)c1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C23H27N3O3/c1-15(2)18-5-3-4-6-20(18)26-11-9-16(10-12-26)23(28)24-17-7-8-21-19(13-17)25-22(27)14-29-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,24,28)(H,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272983
(1-(2-bromo-3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H...)Show SMILES Fc1cccc(N2CCC(CC2)C(=O)Nc2ccc3OCC(=O)Nc3c2)c1Br Show InChI InChI=1S/C20H19BrFN3O3/c21-19-14(22)2-1-3-16(19)25-8-6-12(7-9-25)20(27)23-13-4-5-17-15(10-13)24-18(26)11-28-17/h1-5,10,12H,6-9,11H2,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376257
(CHEMBL258915)Show InChI InChI=1S/C21H23N3O/c1-3-4-13-24(2)19-11-9-16(10-12-19)21(25)23-18-14-17-7-5-6-8-20(17)22-15-18/h5-12,14-15H,3-4,13H2,1-2H3,(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272858
(1-(3-fluorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)Show SMILES Fc1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H20FN3O3/c21-14-2-1-3-16(10-14)24-8-6-13(7-9-24)20(26)22-15-4-5-18-17(11-15)23-19(25)12-27-18/h1-5,10-11,13H,6-9,12H2,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376269
(CHEMBL407231)Show SMILES CCCN(C1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C25H29N3O/c1-2-16-28(22-9-4-3-5-10-22)23-14-12-19(13-15-23)25(29)27-21-17-20-8-6-7-11-24(20)26-18-21/h6-8,11-15,17-18,22H,2-5,9-10,16H2,1H3,(H,27,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272899
(1-(2-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)Show SMILES Clc1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H20ClN3O3/c21-15-3-1-2-4-17(15)24-9-7-13(8-10-24)20(26)22-14-5-6-18-16(11-14)23-19(25)12-27-18/h1-6,11,13H,7-10,12H2,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 93 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272859
(1-(3-chlorophenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b...)Show SMILES Clc1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H20ClN3O3/c21-14-2-1-3-16(10-14)24-8-6-13(7-9-24)20(26)22-15-4-5-18-17(11-15)23-19(25)12-27-18/h1-5,10-11,13H,6-9,12H2,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 97 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273021
(1-(3-chloro-2-methylphenyl)-N-(3-oxo-3,4-dihydro-2...)Show SMILES Cc1c(Cl)cccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H22ClN3O3/c1-13-16(22)3-2-4-18(13)25-9-7-14(8-10-25)21(27)23-15-5-6-19-17(11-15)24-20(26)12-28-19/h2-6,11,14H,7-10,12H2,1H3,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272981
(1-(2-ethylphenyl)-N-(3-oxo-3,4-dihydro-2H-benzo[b]...)Show SMILES CCc1ccccc1N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C22H25N3O3/c1-2-15-5-3-4-6-19(15)25-11-9-16(10-12-25)22(27)23-17-7-8-20-18(13-17)24-21(26)14-28-20/h3-8,13,16H,2,9-12,14H2,1H3,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273057
(1-(3,5-difluorophenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)Show SMILES Fc1cc(F)cc(c1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C20H19F2N3O3/c21-13-7-14(22)9-16(8-13)25-5-3-12(4-6-25)20(27)23-15-1-2-18-17(10-15)24-19(26)11-28-18/h1-2,7-10,12H,3-6,11H2,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 137 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273023
(1-(4-tert-butylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)Show SMILES CC(C)(C)c1ccc(cc1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C24H29N3O3/c1-24(2,3)17-4-7-19(8-5-17)27-12-10-16(11-13-27)23(29)25-18-6-9-21-20(14-18)26-22(28)15-30-21/h4-9,14,16H,10-13,15H2,1-3H3,(H,25,29)(H,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 142 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376270
(CHEMBL406573)Show InChI InChI=1S/C22H23N3O/c26-22(25-20-14-17-6-4-5-9-21(17)23-15-20)16-10-12-19(13-11-16)24-18-7-2-1-3-8-18/h4-6,9-15,18,24H,1-3,7-8H2,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 156 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376259
(CHEMBL258623)Show InChI InChI=1S/C22H24N2O/c1-2-3-4-5-8-17-11-13-18(14-12-17)22(25)24-20-15-19-9-6-7-10-21(19)23-16-20/h6-7,9-16H,2-5,8H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50272897
(CHEMBL455926 | N-(3-oxo-3,4-dihydro-2H-benzo[b][1,...)Show SMILES Cc1cccc(c1)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C21H23N3O3/c1-14-3-2-4-17(11-14)24-9-7-15(8-10-24)21(26)22-16-5-6-19-18(12-16)23-20(25)13-27-19/h2-6,11-12,15H,7-10,13H2,1H3,(H,22,26)(H,23,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 225 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376276
(CHEMBL260448)Show InChI InChI=1S/C20H21N3O/c1-3-12-23(2)18-10-8-15(9-11-18)20(24)22-17-13-16-6-4-5-7-19(16)21-14-17/h4-11,13-14H,3,12H2,1-2H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 267 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50273025
(1-(3,4-dimethylphenyl)-N-(3-oxo-3,4-dihydro-2H-ben...)Show SMILES Cc1ccc(cc1C)N1CCC(CC1)C(=O)Nc1ccc2OCC(=O)Nc2c1 Show InChI InChI=1S/C22H25N3O3/c1-14-3-5-18(11-15(14)2)25-9-7-16(8-10-25)22(27)23-17-4-6-20-19(12-17)24-21(26)13-28-20/h3-6,11-12,16H,7-10,13H2,1-2H3,(H,23,27)(H,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 314 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cell membrane |
Bioorg Med Chem Lett 18: 4569-72 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50147079
(4-Pentyl-N-pyridin-3-yl-benzamide | 4-pentyl-N-pyr...)Show InChI InChI=1S/C17H20N2O/c1-2-3-4-6-14-8-10-15(11-9-14)17(20)19-16-7-5-12-18-13-16/h5,7-13H,2-4,6H2,1H3,(H,19,20) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 421 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376252
(CHEMBL405990)Show InChI InChI=1S/C20H26N2O/c1-2-3-4-5-6-7-9-17-11-13-18(14-12-17)20(23)22-19-10-8-15-21-16-19/h8,10-16H,2-7,9H2,1H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 546 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376251
(CHEMBL259102)Show InChI InChI=1S/C22H30N2O/c1-2-3-4-5-6-7-8-9-11-19-13-15-20(16-14-19)22(25)24-21-12-10-17-23-18-21/h10,12-18H,2-9,11H2,1H3,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 607 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376254
(CHEMBL259396)Show InChI InChI=1S/C16H18N2O/c1-2-3-5-13-7-9-14(10-8-13)16(19)18-15-6-4-11-17-12-15/h4,6-12H,2-3,5H2,1H3,(H,18,19) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 626 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50376258
(CHEMBL261848)Show InChI InChI=1S/C25H30N2O/c1-2-3-4-5-6-7-8-11-20-14-16-21(17-15-20)25(28)27-23-18-22-12-9-10-13-24(22)26-19-23/h9-10,12-19H,2-8,11H2,1H3,(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells |
Bioorg Med Chem Lett 18: 2730-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.075
BindingDB Entry DOI: 10.7270/Q27H1KF6 |
More data for this
Ligand-Target Pair | |
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