Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'tibbitts' and Initial = 'tt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential protein 5 (Rattus norvegicus)	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated rat TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with holdi...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as decrease in current amplitude treated for 3 mins measured between +80 mV and ...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 4 (Homo sapiens)	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of Englerin-activated human TRPC4 channel expressed in HEK293 cells by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529418 (CHEMBL4452948) Show SMILES Cc1cccc(C)c1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C17H19ClN4O2/c1-11-4-3-5-12(2)13(11)9-22-7-6-21(10-15(22)23)14-8-19-20-17(24)16(14)18/h3-5,8H,6-7,9-10H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529427 (CHEMBL4536108) Show SMILES C[C@H](N1CCN(CC1=O)c1cn[nH]c(=O)c1Cl)c1ccccc1C |r| Show InChI InChI=1S/C17H19ClN4O2/c1-11-5-3-4-6-13(11)12(2)22-8-7-21(10-15(22)23)14-9-19-20-17(24)16(14)18/h3-6,9,12H,7-8,10H2,1-2H3,(H,20,24)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529454 (CHEMBL4440201) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H17BrN4O2/c1-11-4-2-3-5-12(11)9-21-7-6-20(10-14(21)22)13-8-18-19-16(23)15(13)17/h2-5,8H,6-7,9-10H2,1H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529447 (CHEMBL4517031) Show SMILES C[C@H]1CC[C@H](CN2CCN(CC2=O)c2cn[nH]c(=O)c2Cl)CC1 |r,wU:4.4,wD:1.0,(47.27,-39.08,;48.6,-38.32,;49.94,-39.1,;51.28,-38.34,;51.28,-36.8,;52.62,-36.04,;53.95,-36.83,;53.93,-38.37,;55.27,-39.16,;56.6,-38.39,;56.61,-36.85,;55.29,-36.07,;55.3,-34.53,;57.93,-39.17,;59.26,-38.4,;60.6,-39.16,;60.6,-40.71,;59.27,-41.48,;59.26,-43.02,;57.93,-40.71,;56.6,-41.48,;49.96,-36.02,;48.62,-36.78,)| Show InChI InChI=1S/C16H23ClN4O2/c1-11-2-4-12(5-3-11)9-21-7-6-20(10-14(21)22)13-8-18-19-16(23)15(13)17/h8,11-12H,2-7,9-10H2,1H3,(H,19,23)/t11-,12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529426 (CHEMBL4475970) Show SMILES FC(F)(F)Oc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O3/c17-14-11(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-12(10)27-16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529449 (CHEMBL4449727) Show SMILES Fc1ccc(CN2CCN(CC2=O)c2cn[nH]c(=O)c2Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C16H13ClF4N4O2/c17-14-12(6-22-23-15(14)27)24-3-4-25(13(26)8-24)7-9-1-2-10(18)5-11(9)16(19,20)21/h1-2,5-6H,3-4,7-8H2,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529450 (CHEMBL4563968) Show SMILES Clc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C15H14Cl2N4O2/c16-11-4-2-1-3-10(11)8-21-6-5-20(9-13(21)22)12-7-18-19-15(23)14(12)17/h1-4,7H,5-6,8-9H2,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529430 (CHEMBL4551777) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H17ClN4O2/c1-11-4-2-3-5-12(11)9-21-7-6-20(10-14(21)22)13-8-18-19-16(23)15(13)17/h2-5,8H,6-7,9-10H2,1H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529452 (CHEMBL4458885) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C1CC1 Show InChI InChI=1S/C19H22N4O2/c1-13-4-2-3-5-15(13)11-23-9-8-22(12-17(23)24)16-10-20-21-19(25)18(16)14-6-7-14/h2-5,10,14H,6-9,11-12H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529440 (CHEMBL4467989) Show SMILES Cc1cc(F)ccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H18BrFN4O/c1-11-8-13(18)3-2-12(11)10-21-4-6-22(7-5-21)14-9-19-20-16(23)15(14)17/h2-3,8-9H,4-7,10H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529444 (CHEMBL4473064) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C#N Show InChI InChI=1S/C17H14F3N5O2/c18-17(19,20)13-4-2-1-3-11(13)9-25-6-5-24(10-15(25)26)14-8-22-23-16(27)12(14)7-21/h1-4,8H,5-6,9-10H2,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529419 (CHEMBL4434976) Show SMILES C[C@@H]1CN(Cc2ccccc2C)CCN1c1cn[nH]c(=O)c1Br |r| Show InChI InChI=1S/C17H21BrN4O/c1-12-5-3-4-6-14(12)11-21-7-8-22(13(2)10-21)15-9-19-20-17(23)16(15)18/h3-6,9,13H,7-8,10-11H2,1-2H3,(H,20,23)/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529420 (CHEMBL4546342) Show SMILES CC(C)c1c(cn[nH]c1=O)N1CCN(Cc2ccccc2C)C(=O)C1 Show InChI InChI=1S/C19H24N4O2/c1-13(2)18-16(10-20-21-19(18)25)22-8-9-23(17(24)12-22)11-15-7-5-4-6-14(15)3/h4-7,10,13H,8-9,11-12H2,1-3H3,(H,21,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529445 (CHEMBL4471419) Show SMILES Cc1ccccc1CN1CC2(C1)CCN(CC2)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C19H23BrN4O/c1-14-4-2-3-5-15(14)11-23-12-19(13-23)6-8-24(9-7-19)16-10-21-22-18(25)17(16)20/h2-5,10H,6-9,11-13H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529422 (CHEMBL4447753) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H19BrN4O/c1-12-4-2-3-5-13(12)11-20-6-8-21(9-7-20)14-10-18-19-16(22)15(14)17/h2-5,10H,6-9,11H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of (-)-Englerin-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529422 (CHEMBL4447753) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H19BrN4O/c1-12-4-2-3-5-13(12)11-20-6-8-21(9-7-20)14-10-18-19-16(22)15(14)17/h2-5,10H,6-9,11H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of lanthanum-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529422 (CHEMBL4447753) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H19BrN4O/c1-12-4-2-3-5-13(12)11-20-6-8-21(9-7-20)14-10-18-19-16(22)15(14)17/h2-5,10H,6-9,11H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529422 (CHEMBL4447753) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H19BrN4O/c1-12-4-2-3-5-13(12)11-20-6-8-21(9-7-20)14-10-18-19-16(22)15(14)17/h2-5,10H,6-9,11H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of riluzole-activated human TRPC5 channel expressed in HEK293 cells measured at holding potential of -60 mV by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529457 (CHEMBL4474451) Show SMILES Brc1c(cn[nH]c1=O)N1CCN(CC2CCCCC2)CC1 Show InChI InChI=1S/C15H23BrN4O/c16-14-13(10-17-18-15(14)21)20-8-6-19(7-9-20)11-12-4-2-1-3-5-12/h10,12H,1-9,11H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529442 (CHEMBL4458766) Show SMILES Cn1ncc2cccc(CN3CCN(CC3=O)c3cn[nH]c(=O)c3Cl)c12 Show InChI InChI=1S/C17H17ClN6O2/c1-22-16-11(7-20-22)3-2-4-12(16)9-24-6-5-23(10-14(24)25)13-8-19-21-17(26)15(13)18/h2-4,7-8H,5-6,9-10H2,1H3,(H,21,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG stably expressed in HEK293 cells measured at holding potential of -90 mV by manual patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529441 (CHEMBL4592027) Show SMILES CC(N1CCN(CC1)c1cn[nH]c(=O)c1Br)c1ccccc1 Show InChI InChI=1S/C16H19BrN4O/c1-12(13-5-3-2-4-6-13)20-7-9-21(10-8-20)14-11-18-19-16(22)15(14)17/h2-6,11-12H,7-10H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529443 (CHEMBL4442703) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C(F)(F)F Show InChI InChI=1S/C17H17F3N4O2/c1-11-4-2-3-5-12(11)9-24-7-6-23(10-14(24)25)13-8-21-22-16(26)15(13)17(18,19)20/h2-5,8H,6-7,9-10H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529432 (CHEMBL4473219) Show SMILES CCc1c(cn[nH]c1=O)N1CCN(Cc2ccccc2C)C(=O)C1 Show InChI InChI=1S/C18H22N4O2/c1-3-15-16(10-19-20-18(15)24)21-8-9-22(17(23)12-21)11-14-7-5-4-6-13(14)2/h4-7,10H,3,8-9,11-12H2,1-2H3,(H,20,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529424 (CHEMBL4436613) Show SMILES FC(F)(F)c1ncccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C15H13ClF3N5O2/c16-12-10(6-21-22-14(12)26)23-4-5-24(11(25)8-23)7-9-2-1-3-20-13(9)15(17,18)19/h1-3,6H,4-5,7-8H2,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529428 (CHEMBL4470341) Show SMILES Cc1ccc(CN2CCN(CC2=O)c2cn[nH]c(=O)c2Cl)cc1 Show InChI InChI=1S/C16H17ClN4O2/c1-11-2-4-12(5-3-11)9-21-7-6-20(10-14(21)22)13-8-18-19-16(23)15(13)17/h2-5,8H,6-7,9-10H2,1H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529455 (CHEMBL4542897) Show SMILES Cc1cccnc1CN1CCN(CC1)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C15H18ClN5O/c1-11-3-2-4-17-12(11)10-20-5-7-21(8-6-20)13-9-18-19-15(22)14(13)16/h2-4,9H,5-8,10H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529456 (CHEMBL4524687) Show SMILES Brc1c(cn[nH]c1=O)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C15H17BrN4O/c16-14-13(10-17-18-15(14)21)20-8-6-19(7-9-20)11-12-4-2-1-3-5-12/h1-5,10H,6-9,11H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529435 (CHEMBL4594091) Show SMILES Cc1ccccc1CN1CCCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C17H21BrN4O/c1-13-5-2-3-6-14(13)12-21-7-4-8-22(10-9-21)15-11-19-20-17(23)16(15)18/h2-3,5-6,11H,4,7-10,12H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529438 (CHEMBL4528028) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cnn(C)c(=O)c1Br Show InChI InChI=1S/C17H21BrN4O/c1-13-5-3-4-6-14(13)12-21-7-9-22(10-8-21)15-11-19-20(2)17(23)16(15)18/h3-6,11H,7-10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529433 (CHEMBL4565194) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C Show InChI InChI=1S/C17H20N4O2/c1-12-5-3-4-6-14(12)10-21-8-7-20(11-16(21)22)15-9-18-19-17(23)13(15)2/h3-6,9H,7-8,10-11H2,1-2H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 6 (Homo sapiens (Human))	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50529421 (CHEMBL4530872) Show SMILES FC(F)(F)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H14ClF3N4O2/c17-14-12(7-21-22-15(14)26)23-5-6-24(13(25)9-23)8-10-3-1-2-4-11(10)16(18,19)20/h1-4,7H,5-6,8-9H2,(H,22,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 stably expressed in CHO cells measured at holding potential of -80 mV by manual patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529423 (CHEMBL4454366) Show SMILES Clc1c(cn[nH]c1=O)N1CCN(CC2CCOCC2)C(=O)C1 Show InChI InChI=1S/C14H19ClN4O3/c15-13-11(7-16-17-14(13)21)18-3-4-19(12(20)9-18)8-10-1-5-22-6-2-10/h7,10H,1-6,8-9H2,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529425 (CHEMBL4475647) Show SMILES CS(=O)(=O)c1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1Cl Show InChI InChI=1S/C16H17ClN4O4S/c1-26(24,25)13-5-3-2-4-11(13)9-21-7-6-20(10-14(21)22)12-8-18-19-16(23)15(12)17/h2-5,8H,6-7,9-10H2,1H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529429 (CHEMBL4439131) Show SMILES COc1c(cn[nH]c1=O)N1CCN(Cc2ccccc2C)C(=O)C1 Show InChI InChI=1S/C17H20N4O3/c1-12-5-3-4-6-13(12)10-21-8-7-20(11-15(21)22)14-9-18-19-17(23)16(14)24-2/h3-6,9H,7-8,10-11H2,1-2H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529431 (CHEMBL4547350) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1C1CCOCC1 Show InChI InChI=1S/C21H26N4O3/c1-15-4-2-3-5-17(15)13-25-9-8-24(14-19(25)26)18-12-22-23-21(27)20(18)16-6-10-28-11-7-16/h2-5,12,16H,6-11,13-14H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529434 (CHEMBL4518299) Show SMILES Cc1ccccc1CN1CC2CCC(C1)N2c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C18H21BrN4O/c1-12-4-2-3-5-13(12)9-22-10-14-6-7-15(11-22)23(14)16-8-20-21-18(24)17(16)19/h2-5,8,14-15H,6-7,9-11H2,1H3,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529436 (CHEMBL4556467) Show SMILES Brc1c(cn[nH]c1=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C16H18BrN3O/c17-15-14(11-18-19-16(15)21)20-8-6-13(7-9-20)10-12-4-2-1-3-5-12/h1-5,11,13H,6-10H2,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529437 (CHEMBL4448384) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cnn(CCCO)c(=O)c1Br Show InChI InChI=1S/C19H25BrN4O2/c1-15-5-2-3-6-16(15)14-22-8-10-23(11-9-22)17-13-21-24(7-4-12-25)19(26)18(17)20/h2-3,5-6,13,25H,4,7-12,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529439 (CHEMBL4590831) Show SMILES Cn1ccnc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C13H17BrN6O/c1-18-3-2-15-11(18)9-19-4-6-20(7-5-19)10-8-16-17-13(21)12(10)14/h2-3,8H,4-7,9H2,1H3,(H,17,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529446 (CHEMBL4436512) Show SMILES C[C@H]1CN(Cc2ccccc2C)CCN1c1cn[nH]c(=O)c1Br |r| Show InChI InChI=1S/C17H21BrN4O/c1-12-5-3-4-6-14(12)11-21-7-8-22(13(2)10-21)15-9-19-20-17(23)16(15)18/h3-6,9,13H,7-8,10-11H2,1-2H3,(H,20,23)/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 6 (Homo sapiens (Human))	BDBM50529422 (CHEMBL4447753) Show SMILES Cc1ccccc1CN1CCN(CC1)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C16H19BrN4O/c1-12-4-2-3-5-13(12)11-20-6-8-21(9-7-20)14-10-18-19-16(22)15(14)17/h2-5,10H,6-9,11H2,1H3,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of OAG-activated human TRPC6 channel expressed in HEK293 cells by Q-patch clamp assay				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529448 (CHEMBL4568038) Show SMILES CC1CN(CCN1Cc1ccccc1C)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C17H21BrN4O/c1-12-5-3-4-6-14(12)11-21-7-8-22(10-13(21)2)15-9-19-20-17(23)16(15)18/h3-6,9,13H,7-8,10-11H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529451 (CHEMBL4469449) Show SMILES Cc1ccccc1CN1CCN(CC1=O)c1cn[nH]c(=O)c1N1CCOCC1 Show InChI InChI=1S/C20H25N5O3/c1-15-4-2-3-5-16(15)13-25-7-6-24(14-18(25)26)17-12-21-22-20(27)19(17)23-8-10-28-11-9-23/h2-5,12H,6-11,13-14H2,1H3,(H,22,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM50529453 (CHEMBL4454641) Show SMILES Cc1ccccc1CN1CC2(C1)CN(C2)c1cn[nH]c(=O)c1Br Show InChI InChI=1S/C17H19BrN4O/c1-12-4-2-3-5-13(12)7-21-8-17(9-21)10-22(11-17)14-6-19-20-16(23)15(14)18/h2-6H,7-11H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Goldfinch Bio Inc. Curated by ChEMBL					Assay Description Inhibition of rosiglitazone-activated human TRPC5 channel expressed in HEK293 cells assessed as reduction in Ca2+ current measured at +80 mV with hol...				ACS Med Chem Lett 10: 1579-1585 (2019) Article DOI: 10.1021/acsmedchemlett.9b00430 BindingDB Entry DOI: 10.7270/Q2DN48HF
					More data for this Ligand-Target Pair

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