Compile Data Set for Download or QSAR

Found 222 hits with Last Name = 'wachter' and Initial = 'mp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50086479 (4-Chloro-benzoic acid N'-p-tolyl-hydrazide | CHEMB...) Show SMILES Cc1ccc(NNC(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C14H13ClN2O/c1-10-2-8-13(9-3-10)16-17-14(18)11-4-6-12(15)7-5-11/h2-9,16H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076649 (CHEMBL369848 | N-{1-methyl-3-[1-(4-methoxyphenyl)-...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(N)=O Show InChI InChI=1S/C21H19ClN4O3/c1-14(26(28)21(23)27)3-8-17-13-20(15-4-6-16(22)7-5-15)25(24-17)18-9-11-19(29-2)12-10-18/h4-7,9-14,28H,1-2H3,(H2,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076666 (CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C23H23N3O3/c1-16-5-8-19(9-6-16)23-15-20(10-7-17(2)26(28)18(3)27)24-25(23)21-11-13-22(29-4)14-12-21/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076661 (CHEMBL177727 | N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-...) Show SMILES CCC(C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-21(27(29)18(3)28)11-10-20-16-24(19-8-6-17(2)7-9-19)26(25-20)22-12-14-23(30-4)15-13-22/h6-9,12-16,21,29H,5H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280333 (CHEMBL49207 | [4,4-Diethyl-6-oxo-1-[2'-(1H-tetrazo...) Show SMILES CCOC(=O)\C=C1/CC(CC)(CC)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C27H31N5O3/c1-4-27(5-2)16-21(15-25(34)35-6-3)32(24(33)17-27)18-19-11-13-20(14-12-19)22-9-7-8-10-23(22)26-28-30-31-29-26/h7-15H,4-6,16-18H2,1-3H3,(H,28,29,30,31)/b21-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50150572 (1-(2-Bromo-phenyl)-3-(2,4-dihydroxy-phenyl)-urea |...) Show SMILES Oc1ccc(NC(=O)Nc2ccccc2Br)c(O)c1 Show InChI InChI=1S/C13H11BrN2O3/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17)7-12(11)18/h1-7,17-18H,(H2,15,16,19)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]-IL-8 (0.125 nM) as radioligand				Bioorg Med Chem Lett 14: 4307-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.080 BindingDB Entry DOI: 10.7270/Q23F4P4M
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076637 (CHEMBL369252 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CCN(O)C(C)=O Show InChI InChI=1S/C22H21N3O3/c1-16-6-8-18(9-7-16)22-15-19(5-4-14-24(27)17(2)26)23-25(22)20-10-12-21(28-3)13-11-20/h6-13,15,27H,14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076659 (CHEMBL435907 | N-{3-[5-(4-Chloro-phenyl)-1-(4-meth...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C22H20ClN3O3/c1-15(26(28)16(2)27)4-9-19-14-22(17-5-7-18(23)8-6-17)25(24-19)20-10-12-21(29-3)13-11-20/h5-8,10-15,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076650 (CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C25H27N3O3/c1-17(2)25(29)28(30)19(4)8-11-21-16-24(20-9-6-18(3)7-10-20)27(26-21)22-12-14-23(31-5)15-13-22/h6-7,9-10,12-17,19,30H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280320 (CHEMBL51084 | [4-Oxo-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCOC(=O)\C=C1/CC2(CCCCC2)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C28H31N5O3/c1-2-36-26(35)16-22-17-28(14-6-3-7-15-28)18-25(34)33(22)19-20-10-12-21(13-11-20)23-8-4-5-9-24(23)27-29-31-32-30-27/h4-5,8-13,16H,2-3,6-7,14-15,17-19H2,1H3,(H,29,30,31,32)/b22-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076642 (2,2,2-Trifluoro-N-hydroxy-N-{3-[1-(4-methoxy-pheny...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(F)(F)F Show InChI InChI=1S/C23H20F3N3O3/c1-15-4-7-17(8-5-15)21-14-18(9-6-16(2)29(31)22(30)23(24,25)26)27-28(21)19-10-12-20(32-3)13-11-19/h4-5,7-8,10-14,16,31H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281520 (CHEMBL123348 | [3-Ethyl-3-methyl-5-oxo-1-[2'-(1H-t...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC1(C)CC Show InChI InChI=1S/C25H27N5O3/c1-4-25(3)15-22(31)30(21(25)14-23(32)33-5-2)16-17-10-12-18(13-11-17)19-8-6-7-9-20(19)24-26-28-29-27-24/h6-14H,4-5,15-16H2,1-3H3,(H,26,27,28,29)/b21-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281522 (CHEMBL121871 | [3-Oxo-2-[2'-(1H-tetrazol-5-yl)-bip...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC11CCCCCC1 Show InChI InChI=1S/C28H31N5O3/c1-2-36-26(35)17-24-28(15-7-3-4-8-16-28)18-25(34)33(24)19-20-11-13-21(14-12-20)22-9-5-6-10-23(22)27-29-31-32-30-27/h5-6,9-14,17H,2-4,7-8,15-16,18-19H2,1H3,(H,29,30,31,32)/b24-17-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076639 (CHEMBL367010 | N-{3-[5-(4-Ethyl-phenyl)-1-(4-metho...) Show SMILES CCc1ccc(cc1)-c1cc(nn1-c1ccc(OC)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-19-7-9-20(10-8-19)24-16-21(11-6-17(2)27(29)18(3)28)25-26(24)22-12-14-23(30-4)15-13-22/h7-10,12-17,29H,5H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076640 (CHEMBL173133 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES CCC(=O)N(O)CC#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C23H23N3O3/c1-4-23(27)25(28)15-5-6-19-16-22(18-9-7-17(2)8-10-18)26(24-19)20-11-13-21(29-3)14-12-20/h7-14,16,28H,4,15H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076644 (CHEMBL175150 | N-{1-ethyl-3-[1-(4-methoxyphenyl)-5...) Show SMILES CCC(C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1)N(O)C(N)=O Show InChI InChI=1S/C23H24N4O3/c1-4-19(27(29)23(24)28)10-9-18-15-22(17-7-5-16(2)6-8-17)26(25-18)20-11-13-21(30-3)14-12-20/h5-8,11-15,19,29H,4H2,1-3H3,(H2,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076657 (CHEMBL368546 | N-hydroxy-N-{3-[1-(4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CCN(O)C(N)=O Show InChI InChI=1S/C21H20N4O3/c1-15-5-7-16(8-6-15)20-14-17(4-3-13-24(27)21(22)26)23-25(20)18-9-11-19(28-2)12-10-18/h5-12,14,27H,13H2,1-2H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076657 (CHEMBL368546 | N-hydroxy-N-{3-[1-(4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CCN(O)C(N)=O Show InChI InChI=1S/C21H20N4O3/c1-15-5-7-16(8-6-15)20-14-17(4-3-13-24(27)21(22)26)23-25(20)18-9-11-19(28-2)12-10-18/h5-12,14,27H,13H2,1-2H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076664 (CHEMBL368145 | N-hydroxy-N-{3-[1-(4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CCN(O)C(N)=O Show InChI InChI=1S/C20H17ClN4O3/c1-28-18-10-8-17(9-11-18)25-19(14-4-6-15(21)7-5-14)13-16(23-25)3-2-12-24(27)20(22)26/h4-11,13,27H,12H2,1H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076666 (CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C23H23N3O3/c1-16-5-8-19(9-6-16)23-15-20(10-7-17(2)26(28)18(3)27)24-25(23)21-11-13-22(29-4)14-12-21/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076664 (CHEMBL368145 | N-hydroxy-N-{3-[1-(4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CCN(O)C(N)=O Show InChI InChI=1S/C20H17ClN4O3/c1-28-18-10-8-17(9-11-18)25-19(14-4-6-15(21)7-5-14)13-16(23-25)3-2-12-24(27)20(22)26/h4-11,13,27H,12H2,1H3,(H2,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076650 (CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C25H27N3O3/c1-17(2)25(29)28(30)19(4)8-11-21-16-24(20-9-6-18(3)7-10-20)27(26-21)22-12-14-23(31-5)15-13-22/h6-7,9-10,12-17,19,30H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280325 (CHEMBL48459 | [4-Ethyl-6-oxo-4-propyl-1-[2'-(1H-te...) Show SMILES CCCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)\C(C1)=C\C(=O)OCC Show InChI InChI=1S/C28H33N5O3/c1-4-15-28(5-2)17-22(16-26(35)36-6-3)33(25(34)18-28)19-20-11-13-21(14-12-20)23-9-7-8-10-24(23)27-29-31-32-30-27/h7-14,16H,4-6,15,17-19H2,1-3H3,(H,29,30,31,32)/b22-16+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281524 (CHEMBL123713 | [3,3-Diethyl-5-oxo-1-[2'-(1H-tetraz...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC1(CC)CC Show InChI InChI=1S/C26H29N5O3/c1-4-26(5-2)16-23(32)31(22(26)15-24(33)34-6-3)17-18-11-13-19(14-12-18)20-9-7-8-10-21(20)25-27-29-30-28-25/h7-15H,4-6,16-17H2,1-3H3,(H,27,28,29,30)/b22-15-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076650 (CHEMBL368682 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C25H27N3O3/c1-17(2)25(29)28(30)19(4)8-11-21-16-24(20-9-6-18(3)7-10-20)27(26-21)22-12-14-23(31-5)15-13-22/h6-7,9-10,12-17,19,30H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076659 (CHEMBL435907 | N-{3-[5-(4-Chloro-phenyl)-1-(4-meth...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C22H20ClN3O3/c1-15(26(28)16(2)27)4-9-19-14-22(17-5-7-18(23)8-6-17)25(24-19)20-10-12-21(29-3)13-11-20/h5-8,10-15,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076666 (CHEMBL175153 | N-Hydroxy-N-{3-[1-(4-methoxy-phenyl...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C23H23N3O3/c1-16-5-8-19(9-6-16)23-15-20(10-7-17(2)26(28)18(3)27)24-25(23)21-11-13-22(29-4)14-12-21/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50086492 (1,3-Diphenyl-1,4,5,6,7,8-hexahydro-cycloheptapyraz...) Show SMILES C1CCc2c(CC1)n(nc2-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C20H20N2/c1-4-10-16(11-5-1)20-18-14-8-3-9-15-19(18)22(21-20)17-12-6-2-7-13-17/h1-2,4-7,10-13H,3,8-9,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 1 in platelet-rich plasma measured by the presence of thromboxane A2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280329 (CHEMBL50906 | [4-Methyl-6-oxo-4-propyl-1-[2'-(1H-t...) Show SMILES CCCC1(C)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)\C(C1)=C\C(=O)OCC Show InChI InChI=1S/C27H31N5O3/c1-4-14-27(3)16-21(15-25(34)35-5-2)32(24(33)17-27)18-19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-28-30-31-29-26/h6-13,15H,4-5,14,16-18H2,1-3H3,(H,28,29,30,31)/b21-15+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280321 (CHEMBL296731 | [4-Isopropyl-4-methyl-6-oxo-1-[2'-(...) Show SMILES CCOC(=O)\C=C1/CC(C)(CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(C)C Show InChI InChI=1S/C27H31N5O3/c1-5-35-25(34)14-21-15-27(4,18(2)3)16-24(33)32(21)17-19-10-12-20(13-11-19)22-8-6-7-9-23(22)26-28-30-31-29-26/h6-14,18H,5,15-17H2,1-4H3,(H,28,29,30,31)/b21-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50086500 (4-Chloro-benzoic acid N'-(4-methoxy-phenyl)-hydraz...) Show SMILES COc1ccc(NNC(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C14H13ClN2O2/c1-19-13-8-6-12(7-9-13)16-17-14(18)10-2-4-11(15)5-3-10/h2-9,16H,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50086498 (3-(4-Chloro-phenyl)-1-phenyl-1,4,5,6,7,8-hexahydro...) Show SMILES Clc1ccc(cc1)-c1nn(c2CCCCCc12)-c1ccccc1 Show InChI InChI=1S/C20H19ClN2/c21-16-13-11-15(12-14-16)20-18-9-5-2-6-10-19(18)23(22-20)17-7-3-1-4-8-17/h1,3-4,7-8,11-14H,2,5-6,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281519 (CHEMBL124449 | [3-Oxo-2-[2'-(1H-tetrazol-5-yl)-bip...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC11CCCCC1 Show InChI InChI=1S/C27H29N5O3/c1-2-35-25(34)16-23-27(14-6-3-7-15-27)17-24(33)32(23)18-19-10-12-20(13-11-19)21-8-4-5-9-22(21)26-28-30-31-29-26/h4-5,8-13,16H,2-3,6-7,14-15,17-18H2,1H3,(H,28,29,30,31)/b23-16-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076662 (CHEMBL174684 | methyl 1-methyl-3-[1-(4-methoxyphen...) Show SMILES COC(=O)N(O)C(C)C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C23H23N3O4/c1-16-5-8-18(9-6-16)22-15-19(10-7-17(2)26(28)23(27)30-4)24-25(22)20-11-13-21(29-3)14-12-20/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Cyclooxygenase (COX) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076659 (CHEMBL435907 | N-{3-[5-(4-Chloro-phenyl)-1-(4-meth...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(C)=O Show InChI InChI=1S/C22H20ClN3O3/c1-15(26(28)16(2)27)4-9-19-14-22(17-5-7-18(23)8-6-17)25(24-19)20-10-12-21(29-3)13-11-20/h5-8,10-15,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50086492 (1,3-Diphenyl-1,4,5,6,7,8-hexahydro-cycloheptapyraz...) Show SMILES C1CCc2c(CC1)n(nc2-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C20H20N2/c1-4-10-16(11-5-1)20-18-14-8-3-9-15-19(18)22(21-20)17-12-6-2-7-13-17/h1-2,4-7,10-13H,3,8-9,14-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076641 (CHEMBL176844 | N-{3-[5-(4-Ethyl-phenyl)-1-(4-metho...) Show SMILES CCc1ccc(cc1)-c1cc(nn1-c1ccc(OC)cc1)C#CC(C)N(O)C(=O)C(C)C Show InChI InChI=1S/C26H29N3O3/c1-6-20-8-10-21(11-9-20)25-17-22(12-7-19(4)29(31)26(30)18(2)3)27-28(25)23-13-15-24(32-5)16-14-23/h8-11,13-19,31H,6H2,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50086487 (Benzoic acid N'-(4-methoxy-phenyl)-hydrazide | CHE...) Show SMILES COc1ccc(NNC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C14H14N2O2/c1-18-13-9-7-12(8-10-13)15-16-14(17)11-5-3-2-4-6-11/h2-10,15H,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human prostaglandin G/H synthase 2 in ECV-304 cells measured by the presence of PGE-2				Bioorg Med Chem Lett 10: 601-4 (2000) BindingDB Entry DOI: 10.7270/Q2TH8KWZ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280323 (CHEMBL51622 | [4-Butyl-4-ethyl-6-oxo-1-[2'-(1H-tet...) Show SMILES CCCCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)\C(C1)=C\C(=O)OCC Show InChI InChI=1S/C29H35N5O3/c1-4-7-16-29(5-2)18-23(17-27(36)37-6-3)34(26(35)19-29)20-21-12-14-22(15-13-21)24-10-8-9-11-25(24)28-30-32-33-31-28/h8-15,17H,4-7,16,18-20H2,1-3H3,(H,30,31,32,33)/b23-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076642 (2,2,2-Trifluoro-N-hydroxy-N-{3-[1-(4-methoxy-pheny...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C)N(O)C(=O)C(F)(F)F Show InChI InChI=1S/C23H20F3N3O3/c1-15-4-7-17(8-5-15)21-14-18(9-6-16(2)29(31)22(30)23(24,25)26)27-28(21)19-10-12-20(32-3)13-11-19/h4-5,7-8,10-14,16,31H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280322 (CHEMBL413098 | [4-Methyl-6-oxo-1-[2'-(1H-tetrazol-...) Show SMILES CCOC(=O)\C=C1/CC(C)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H25N5O3/c1-3-32-23(31)14-19-12-16(2)13-22(30)29(19)15-17-8-10-18(11-9-17)20-6-4-5-7-21(20)24-25-27-28-26-24/h4-11,14,16H,3,12-13,15H2,1-2H3,(H,25,26,27,28)/b19-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50280328 (CHEMBL418269 | [4,4-Diethyl-6-oxo-1-[2'-(1H-tetraz...) Show SMILES CCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)\C(C1)=C\C(=O)OC Show InChI InChI=1S/C26H29N5O3/c1-4-26(5-2)15-20(14-24(33)34-3)31(23(32)16-26)17-18-10-12-19(13-11-18)21-8-6-7-9-22(21)25-27-29-30-28-25/h6-14H,4-5,15-17H2,1-3H3,(H,27,28,29,30)/b20-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076661 (CHEMBL177727 | N-{1-Ethyl-3-[1-(4-methoxy-phenyl)-...) Show SMILES CCC(C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1)N(O)C(C)=O Show InChI InChI=1S/C24H25N3O3/c1-5-21(27(29)18(3)28)11-10-20-16-24(19-8-6-17(2)7-9-19)26(25-20)22-12-14-23(30-4)15-13-22/h6-9,12-16,21,29H,5H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076653 (CHEMBL366595 | N-{1-isopropyl-3-[1-(4-methoxypheny...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C(C)C)N(O)C(N)=O Show InChI InChI=1S/C24H26N4O3/c1-16(2)22(28(30)24(25)29)14-9-19-15-23(18-7-5-17(3)6-8-18)27(26-19)20-10-12-21(31-4)13-11-20/h5-8,10-13,15-16,22,30H,1-4H3,(H2,25,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076653 (CHEMBL366595 | N-{1-isopropyl-3-[1-(4-methoxypheny...) Show SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(C)cc1)C#CC(C(C)C)N(O)C(N)=O Show InChI InChI=1S/C24H26N4O3/c1-16(2)22(28(30)24(25)29)14-9-19-15-23(18-7-5-17(3)6-8-18)27(26-19)20-10-12-21(31-4)13-11-20/h5-8,10-13,15-16,22,30H,1-4H3,(H2,25,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50281523 (CHEMBL421094 | [3-Oxo-2-[2'-(1H-tetrazol-5-yl)-bip...) Show SMILES CCOC(=O)\C=C1/N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(=O)CC11CCCC1 Show InChI InChI=1S/C26H27N5O3/c1-2-34-24(33)15-22-26(13-5-6-14-26)16-23(32)31(22)17-18-9-11-19(12-10-18)20-7-3-4-8-21(20)25-27-29-30-28-25/h3-4,7-12,15H,2,5-6,13-14,16-17H2,1H3,(H,27,28,29,30)/b22-15-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration that gives 50% inhibition for binding of 125-I-[Sar1, IIe8] angiotensin to Angiotensin II receptor, type 1 in bovine adrenal cortex mem...				Bioorg Med Chem Lett 3: 369-374 (1993) Article DOI: 10.1016/S0960-894X(01)80914-8 BindingDB Entry DOI: 10.7270/Q20G3K2H
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Bos taurus)	BDBM50049205 (CHEMBL48602 | RWJ-46458 | [4-Ethyl-4-methyl-6-oxo-...) Show SMILES CCOC(=O)\C=C1/CC(C)(CC)CC(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C26H29N5O3/c1-4-26(3)15-20(14-24(33)34-5-2)31(23(32)16-26)17-18-10-12-19(13-11-18)21-8-6-7-9-22(21)25-27-29-30-28-25/h6-14H,4-5,15-17H2,1-3H3,(H,27,28,29,30)/b20-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes				Bioorg Med Chem Lett 2: 1775-1779 (1992) Article DOI: 10.1016/S0960-894X(00)80474-6 BindingDB Entry DOI: 10.7270/Q2NP24B9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50076662 (CHEMBL174684 | methyl 1-methyl-3-[1-(4-methoxyphen...) Show SMILES COC(=O)N(O)C(C)C#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C23H23N3O4/c1-16-5-8-18(9-6-16)22-15-19(10-7-17(2)26(28)23(27)30-4)24-25(22)20-11-13-21(29-3)14-12-20/h5-6,8-9,11-15,17,28H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076651 (CHEMBL174976 | methyl-3-[1-(4-methoxyphenyl)-5-(4-...) Show SMILES COC(=O)N(O)CC#Cc1cc(-c2ccc(C)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C22H21N3O4/c1-16-6-8-17(9-7-16)21-15-18(5-4-14-24(27)22(26)29-3)23-25(21)19-10-12-20(28-2)13-11-19/h6-13,15,27H,14H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50076658 (CHEMBL174501 | methyl 3-[5-(4-chlorophenyl)-1-(4-m...) Show SMILES COC(=O)N(O)C(C)C#Cc1cc(-c2ccc(Cl)cc2)n(n1)-c1ccc(OC)cc1 Show InChI InChI=1S/C22H20ClN3O4/c1-15(26(28)22(27)30-3)4-9-18-14-21(16-5-7-17(23)8-6-16)25(24-18)19-10-12-20(29-2)13-11-19/h5-8,10-15,28H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
The R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)				Bioorg Med Chem Lett 9: 979-84 (1999) BindingDB Entry DOI: 10.7270/Q2Z31XV3
					More data for this Ligand-Target Pair

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