BindingDB PrimarySearch

Found 15513 hits with Last Name = 'yan' and Initial = 'd'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50379086 (CHEMBL2012521 \| CHEMBL2012522 \| LY-377604) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.0120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]Iodocyanopindolol from human adrenergic beta2 receptor expressed in insect sf9 cells by scintillation counting				ACS Med Chem Lett 2: 583-586 (2011) Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50179190 (2-(2-(((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin II from rat delta opioid receptor in brain P2 synaptosomes				J Med Chem 48: 8112-4 (2005) Article DOI: 10.1021/jm058259l BindingDB Entry DOI: 10.7270/Q24J0DQR
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50121649 (2-[({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50194487 (3-[4'-(H-Dmt)-aminobutyl]-6-[3'-(H-Dmt)-aminopropy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat synaptosomes P2 fraction				Bioorg Med Chem Lett 16: 5793-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.079 BindingDB Entry DOI: 10.7270/Q26Q1WWH
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50379086 (CHEMBL2012521 \| CHEMBL2012522 \| LY-377604) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.0230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation counting				ACS Med Chem Lett 2: 583-586 (2011) Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102777 (US8541572, 2207) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0300	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102624 (US8541572, 303) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0300	n/a	383	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50266025 ((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Brussels Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				J Med Chem 49: 3990-3 (2006) Article DOI: 10.1021/jm0603264 BindingDB Entry DOI: 10.7270/Q2474BPW
Vrije Universiteit Brussels Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50266025 ((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assay				J Med Chem 45: 713-20 (2002) BindingDB Entry DOI: 10.7270/Q2639QFF
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50179191 ((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assay				J Med Chem 45: 713-20 (2002) BindingDB Entry DOI: 10.7270/Q2639QFF
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50027229 (CHEMBL2375157) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Brussels Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				J Med Chem 49: 3990-3 (2006) Article DOI: 10.1021/jm0603264 BindingDB Entry DOI: 10.7270/Q2474BPW
Vrije Universiteit Brussels Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50179191 ((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50157686 (5-[({5-[(2S)-2-({2-[(2S)-2-amino-3-(4-hydroxy-2,6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat brain synaptosomes P2 fraction				J Med Chem 47: 6541-6 (2004) Article DOI: 10.1021/jm040128h BindingDB Entry DOI: 10.7270/Q28W3CS2
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50179191 ((S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin II from rat delta opioid receptor in brain P2 synaptosomes				J Med Chem 48: 8112-4 (2005) Article DOI: 10.1021/jm058259l BindingDB Entry DOI: 10.7270/Q24J0DQR
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17428 (1,2,4-Triazole Compound, 86 \| N-[5-(benzylsulfanyl...) Show SMILES C(Sc1nnc(Nc2cccnc2)[nH]1)c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
GSK					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17355 (1,2,4-Triazole Compound, 13 \| 5-(benzylsulfanyl)-N...) Show SMILES Cc1ccccc1Nc1nnc(SCc2ccccc2)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0400	-58.8	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
GSK					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083160 ((S)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 from rat brain synaptosomal preparations by H-Dmt-Tic-OH displacement.				J Med Chem 42: 5010-9 (2000) BindingDB Entry DOI: 10.7270/Q2VX0FQG
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130611 (2-Amino-N-{4-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50272081 (2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Brussels Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				J Med Chem 49: 3990-3 (2006) Article DOI: 10.1021/jm0603264 BindingDB Entry DOI: 10.7270/Q2474BPW
Vrije Universiteit Brussels Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50272081 (2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assay				J Med Chem 45: 713-20 (2002) BindingDB Entry DOI: 10.7270/Q2639QFF
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221787 (CHEMBL3216418) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Environmental Health Sciences Curated by ChEMBL					Assay Description Compound was tested for Opioid receptor mu 1 agonism in isolated tissues from guinea pig ileum				J Med Chem 47: 2599-610 (2004) Article DOI: 10.1021/jm0304616 BindingDB Entry DOI: 10.7270/Q2RB755V
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50121648 (2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50212613 (CHEMBL266122 \| Tyr-Pro-Dmp-Phe-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membrane				J Med Chem 50: 2753-66 (2007) Article DOI: 10.1021/jm061238m BindingDB Entry DOI: 10.7270/Q25B0264
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50049378 (1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]-DPDPE (0.63 nM) from Opioid receptor delta 1				J Med Chem 39: 773-80 (1996) Article DOI: 10.1021/jm950490j BindingDB Entry DOI: 10.7270/Q2QV3KKJ
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50121645 (2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)pr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17388 (1,2,4-Triazole Compound, 46 \| 5-(benzylsulfanyl)-N...) Show SMILES COc1ccc(Nc2nnc(SCc3ccccc3)[nH]2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
GSK					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130617 (2-Amino-N-{6-[2-amino-3-(4-hydroxy-2,6-dimethyl-ph...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 using [3H]-DAGO in rat brain P2 synaptosomal preparation				J Med Chem 46: 3201-9 (2003) Article DOI: 10.1021/jm020459z BindingDB Entry DOI: 10.7270/Q28C9VMQ
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50194488 (6-[4'-(H-Dmt)-aminobutyl]-3-[3'-(H-Dmt)-aminopropy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat synaptosomes P2 fraction				Bioorg Med Chem Lett 16: 5793-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.079 BindingDB Entry DOI: 10.7270/Q26Q1WWH
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102623 (US8541572, 302) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0521	n/a	723	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102666 (US8541572, 973) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0524	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50199865 ((S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-y...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosome				Bioorg Med Chem 15: 1237-51 (2007) Article DOI: 10.1016/j.bmc.2006.11.019 BindingDB Entry DOI: 10.7270/Q2348K1F
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50049376 (1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]-DPDPE (0.63 nM) from Opioid receptor delta 1				J Med Chem 39: 773-80 (1996) Article DOI: 10.1021/jm950490j BindingDB Entry DOI: 10.7270/Q2QV3KKJ
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50049377 (1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Displacement of [3H]-DPDPE (0.63 nM) from Opioid receptor delta 1				J Med Chem 39: 773-80 (1996) Article DOI: 10.1021/jm950490j BindingDB Entry DOI: 10.7270/Q2QV3KKJ
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102663 (US8541572, 970) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0556	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083154 ((S)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 from rat brain synaptosomal preparations by [3H]N,N-(Me)2-Dmt-Tic-OH displacement.				J Med Chem 42: 5010-9 (2000) BindingDB Entry DOI: 10.7270/Q2VX0FQG
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102802 (US8541572, 2234) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0600	n/a	678	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50157684 (CHEMBL2369958 \| H-Dmt-Tic-Glu-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain synaptosomes P2 fraction				J Med Chem 47: 6541-6 (2004) Article DOI: 10.1021/jm040128h BindingDB Entry DOI: 10.7270/Q28W3CS2
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50332270 ((R)-3-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of TACE				Bioorg Med Chem Lett 20: 7283-7 (2010) Article DOI: 10.1016/j.bmcl.2010.10.081 BindingDB Entry DOI: 10.7270/Q2Z89CP0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50178759 (1,6-bis-(N,N-dimethyl-Dmt-Tic-NH)hexane \| CHEMBL37...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranes				J Med Chem 48: 8035-44 (2005) Article DOI: 10.1021/jm050377l BindingDB Entry DOI: 10.7270/Q2C53KD9
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50157684 (CHEMBL2369958 \| H-Dmt-Tic-Glu-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from delta opioid receptor in rat brain synaptosomes P2 fraction				J Med Chem 47: 6541-6 (2004) Article DOI: 10.1021/jm040128h BindingDB Entry DOI: 10.7270/Q28W3CS2
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102680 (US8541572, 987) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0627	n/a	75.4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102845 (US8541572, 927) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0630	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50159681 ((S)-1-[2-Amino-3-(2-ethyl-4-hydroxy-6-methyl-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Inhibition of [3H]-DAMGO binding to mu-Opioid receptor				J Med Chem 48: 586-92 (2005) Article DOI: 10.1021/jm049384k BindingDB Entry DOI: 10.7270/Q26T0M40
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50121645 (2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)pr...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM102664 (US8541572, 971) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0651	n/a	80.3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibition assay using TNF-alpha.				US Patent US8541572 (2013) BindingDB Entry DOI: 10.7270/Q2QC024J
Merck Sharp & Dohme Corp. US Patent					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50083169 ((S)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 from rat brain synaptosomal preparations by [3H]N,N-(Me)2-Dmt-Tic-OH displacement.				J Med Chem 42: 5010-9 (2000) BindingDB Entry DOI: 10.7270/Q2VX0FQG
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50108919 (2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliari Curated by ChEMBL					Assay Description Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomes				J Med Chem 45: 5556-63 (2002) BindingDB Entry DOI: 10.7270/Q2BR8SWH
University of Cagliari Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50108919 (2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	0.0670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Cagliary Curated by ChEMBL					Assay Description Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assay				J Med Chem 45: 713-20 (2002) BindingDB Entry DOI: 10.7270/Q2639QFF
University of Cagliary Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50212609 (CHEMBL228409 \| Dmt-Pro-Dmp-Phe-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Gakuin University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membrane				J Med Chem 50: 2753-66 (2007) Article DOI: 10.1021/jm061238m BindingDB Entry DOI: 10.7270/Q25B0264
Kobe Gakuin University Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001459 (3-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylam...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Tested for inhibition of amplification of electrically induced twitch in guinea pig ileum (GPI)				J Med Chem 36: 3748-56 (1994) BindingDB Entry DOI: 10.7270/Q2D799HM
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair

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