Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419548 (CHEMBL1929281) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50003027 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50067013 (1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419545 (CHEMBL1929278) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50065941 (1-{2-[4-(6-Methoxy-2-phenyl-3,4-dihydro-naphthalen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM19441 (2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170657 (1''-butyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170652 ((2R,6S)-2,6-Dimethyl-4-tridecyl-morpholine | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM55354 (CLOMIPHENE | CLOMIPHENE CITRATE | MLS000069760 | S...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419544 (CHEMBL1929277) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50299708 (1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronap...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from EBP in Dunkin guinea pig liver membrane by radioreceptor binding assay | J Med Chem 52: 7817-28 (2009) Article DOI: 10.1021/jm9007505 BindingDB Entry DOI: 10.7270/Q2CJ8FDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419543 (CHEMBL1929275) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50338990 (1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Stanford University Curated by ChEMBL | Assay Description Binding affinity to EBP | J Med Chem 55: 8272-82 (2012) Article DOI: 10.1021/jm300371c BindingDB Entry DOI: 10.7270/Q2V40WB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50338990 (1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Radiopharmaceuticals (Beijing Normal University) Curated by ChEMBL | Assay Description Binding affinity to emopamil binding protein | Bioorg Med Chem 19: 2911-7 (2011) Article DOI: 10.1016/j.bmc.2011.03.037 BindingDB Entry DOI: 10.7270/Q2QJ7HN1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50338990 (1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Radiopharmaceuticals Beijing Normal University Curated by ChEMBL | Assay Description Binding affinity to EBP (unknown origin) | J Med Chem 56: 3478-91 (2013) Article DOI: 10.1021/jm301734g BindingDB Entry DOI: 10.7270/Q28W3FN3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50338990 (1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Radiopharmacy Curated by ChEMBL | Assay Description Binding affinity to EBP | Bioorg Med Chem 20: 257-69 (2011) Article DOI: 10.1016/j.bmc.2011.11.002 BindingDB Entry DOI: 10.7270/Q2NG4R2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179265 (1-(4-(6-methoxynaphthalen-1-yl)butyl)-4,4-dimethyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179277 (1-(4-(6-methoxynaphthalen-1-yl)butyl)-3,3-dimethyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM71545 (2-[4-[(Z)-2-chloranyl-1,2-diphenyl-ethenyl]phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170651 ((3S,8R,9S,10R,13S,14S)-3-(2-Diethylamino-ethoxy)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170659 (2-[3-(Methyl-phenethyl-amino)-propyl]-2-phenyl-tet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419547 (CHEMBL1929280) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane | J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179263 ((+)-(S)-1-(4-(6-methoxynaphthalen-1-yl)butyl)-3-me...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170641 (CHEMBL188476 | [(E)-3-(3-Chloro-4-cyclohexyl-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50359687 (CHEMBL1929279 | CHEMBL1929431) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.07 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50128105 (1-[2-(4-Chloro-phenoxy)-propyl]-4-methyl-piperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane | J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179270 ((+)-(S)-1-(3-(6-methoxynaphthalen-1-yl)propyl)-3-m...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179259 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50128110 (1-[2-(4-Chloro-phenoxy)-ethyl]-4-methyl-piperidine...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane | J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50128107 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Inhibition of [3H]-emopamil binding to Sterol delta 8-delta 7 isomerase in guinea pig liver membrane | J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50419550 (CHEMBL1929287) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H]-emopamil from delta(8)-delta(7) sterol isomerase in guinea pig liver membranes | Bioorg Med Chem 19: 7612-22 (2011) Article DOI: 10.1016/j.bmc.2011.10.023 BindingDB Entry DOI: 10.7270/Q2RX9CHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170650 ((2-{4-[(2-Chloro-benzylamino)-methyl]-cyclohexyl}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179262 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50219749 (3,3-dimethyl-1-[3-(7-methoxynaphthalen-1-yl)propyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membrane | J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50145022 (1-Cyclohexyl-4-[3-(5-methoxy-naphthalen-1-yl)-prop...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membrane | J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50007674 ((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50299726 (1-cyclohexyl-4-(3-cyclohexylpropyl)piperazine | CH...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from EBP in Dunkin guinea pig liver membrane by radioreceptor binding assay | J Med Chem 52: 7817-28 (2009) Article DOI: 10.1021/jm9007505 BindingDB Entry DOI: 10.7270/Q2CJ8FDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50274948 (CHEMBL457722 | cis-4-[4-(2,6-Dimethoxyphenyl)cyclo...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane | J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50080017 ((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM20607 ((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50274839 (CHEMBL456435 | cis-4-[4-(2-Methylphenyl)cyclohexyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane | J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179285 (1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179281 (1-(3-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179269 (1-(4-(6-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Homo sapiens (Human)) | BDBM50170648 ((R)-2-Isopropyl-5-(methyl-phenethyl-amino)-2-pheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Affinity for human EMP expressed in ERG2 deficient strain of Sacchromyces cerevisiae using [3H]ifenprodil or (+)-[3H]pentazocine as radioligand | J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50179275 ((-)-(R)-1-(4-(6-methoxynaphthalen-1-yl)butyl)-2-me...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H](+/-)-emopamil from delta8-delta7 sterol isomerase (SI) site in guinea pig liver membranes | J Med Chem 48: 8237-44 (2005) Article DOI: 10.1021/jm050654o BindingDB Entry DOI: 10.7270/Q2MP542J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50274970 (CHEMBL513936 | trans-4-[4-(2,6-Dimethoxyphenyl)cyc...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane | J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50219751 (1-cyclohexyl-4-[3-(6-methoxynaphthalen-1-yl)propyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.06 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Bari Curated by ChEMBL | Assay Description Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membrane | J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Cavia porcellus) | BDBM50274945 (CHEMBL457720 | trans-4-[4-(2-Chlorophenyl)cyclohex...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari Curated by ChEMBL | Assay Description Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membrane | J Med Chem 51: 7523-31 (2009) Article DOI: 10.1021/jm800965b BindingDB Entry DOI: 10.7270/Q21837D3 | |||||||||||
More data for this Ligand-Target Pair |
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