Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50520846 (CHEMBL4461911) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 581 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST) Curated by ChEMBL | Assay Description Inhibition of human DAPK1 (1 to 363 residues) using KKLNRTLSFAEPG as substrate after 120 mins [gamma-33P]-ATP by filtration method | Eur J Med Chem 162: 161-175 (2019) Article DOI: 10.1016/j.ejmech.2018.10.057 BindingDB Entry DOI: 10.7270/Q29K4FM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50463483 (CHEMBL4245242) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of DAPK1 (unknown origin) | Bioorg Med Chem Lett 28: 2622-2626 (2018) Article DOI: 10.1016/j.bmcl.2018.06.040 BindingDB Entry DOI: 10.7270/Q2ZC85HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Death-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50463479 (CHEMBL4249925) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of DAPK1 (unknown origin) | Bioorg Med Chem Lett 28: 2622-2626 (2018) Article DOI: 10.1016/j.bmcl.2018.06.040 BindingDB Entry DOI: 10.7270/Q2ZC85HX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236338 (US9365576, 91) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0610 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236270 (US9365576, 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0650 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236261 (US9365576, 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0680 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236476 (US9365576, 232) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0690 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236471 (US9365576, 227) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0710 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236267 (US9365576, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0750 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236473 (US9365576, 229) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0780 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236435 (US9365576, 188) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0790 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236336 (US9365576, 89) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236368 (US9365576, 121 | US9365576, 218) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0870 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236279 (US9365576, 32) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0940 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236265 (US9365576, 18) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0950 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215394 (US9296736, 375 | US9593129, Example 375) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215412 (US9296736, 399 | US9593129, Example 399) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50053052 (CHEMBL3318767 | US9296736, 379 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50448945 (CHEMBL3125521 | US9296736, 381 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215307 (US9296736, 268 | US9593129, Example 268) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215310 (US9296736, 272) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50053040 (CHEMBL3318760 | US9296736, 378 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215390 (US9296736, 371 | US9593129, Example 371) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215379 (US9296736, 358 | US9593129, Example 358) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50448955 (CHEMBL3125701 | US9296736, 354 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50448959 (CHEMBL3125697 | US9296736, 350 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215370 (US9296736, 346 | US9593129, Example 346) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215340 (US9296736, 308 | US9593129, Example 308) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215346 (US9296736, 314 | US9593129, Example 314) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215366 (US9296736, 334 | US9593129, Example 334) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50448936 (CHEMBL3125527 | US9296736, 342 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215373 (US9296736, 349 | US9593129, Example 349) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM50448963 (CHEMBL3125537 | US9296736, 351 | US9593129, Exampl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215375 (US9296736, 353 | US9593129, Example 353) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215385 (US9296736, 366 | US9593129, Example 366) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215410 (US9296736, 398 | US9593129, Example 398) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215308 (US9296736, 269 | US9593129, Example 269) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215343 (US9296736, 311 | US9296736, 312 | US9593129, Examp...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188] (Homo sapiens (Human)) | BDBM215354 (US9296736, 322 | US9593129, Example 322) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Amgen INC. US Patent | Assay Description The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in... | US Patent US9296736 (2016) BindingDB Entry DOI: 10.7270/Q29022M2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236308 (US9365576, 61) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.104 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236368 (US9365576, 121 | US9365576, 218) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.106 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236370 (US9365576, 123) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.106 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236275 (US9365576, 28) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.106 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236481 (US9365576, 237) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.107 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236433 (US9365576, 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.108 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236396 (US9365576, 149) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236258 (US9365576, 11) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.113 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236327 (US9365576, 80) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.115 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236283 (US9365576, 36) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.115 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188] (Homo sapiens (Human)) | BDBM236257 (US9365576, 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.116 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou... | US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR | |||||||||||
More data for this Ligand-Target Pair |
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