Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50021892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229083 (2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC1)C(=O)CN Show InChI InChI=1S/C22H23BrN6O2S2/c1-14-5-6-15(11-16(14)21(31)29-9-7-28(8-10-29)19(30)12-24)32-20-13-25-22(33-20)27-18-4-2-3-17(23)26-18/h2-6,11,13H,7-10,12,24H2,1H3,(H,25,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229082 (1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C22H22BrN5O2S2/c1-14-6-7-16(12-17(14)21(30)28-10-8-27(9-11-28)15(2)29)31-20-13-24-22(32-20)26-19-5-3-4-18(23)25-19/h3-7,12-13H,8-11H2,1-2H3,(H,24,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229085 ((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229087 ((S)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229086 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CN(CC#N)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C19H16BrN5OS2/c1-12-6-7-13(10-14(12)18(26)25(2)9-8-21)27-17-11-22-19(28-17)24-16-5-3-4-15(20)23-16/h3-7,10-11H,9H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229095 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CN(CCC#N)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C20H18BrN5OS2/c1-13-7-8-14(11-15(13)19(27)26(2)10-4-9-22)28-18-12-23-20(29-18)25-17-6-3-5-16(21)24-17/h3,5-8,11-12H,4,10H2,1-2H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229116 (1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CCC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H24BrN5O2S2/c1-3-20(30)28-9-11-29(12-10-28)22(31)17-13-16(8-7-15(17)2)32-21-14-25-23(33-21)27-19-6-4-5-18(24)26-19/h4-8,13-14H,3,9-12H2,1-2H3,(H,25,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229101 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CNCCN(C)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C20H22BrN5OS2/c1-13-7-8-14(11-15(13)19(27)26(3)10-9-22-2)28-18-12-23-20(29-18)25-17-6-4-5-16(21)24-17/h4-8,11-12,22H,9-10H2,1-3H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229100 (CHEMBL253858 | N-(cyanomethyl)-2-methyl-5-(2-(pyri...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)NCC#N Show InChI InChI=1S/C18H15N5OS2/c1-12-5-6-13(10-14(12)17(24)21-9-7-19)25-16-11-22-18(26-16)23-15-4-2-3-8-20-15/h2-6,8,10-11H,9H2,1H3,(H,21,24)(H,20,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229113 (1-(4-(3-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(Sc2cnc(Nc3cccc(Br)n3)s2)c1 Show InChI InChI=1S/C21H20BrN5O2S2/c1-14(28)26-8-10-27(11-9-26)20(29)15-4-2-5-16(12-15)30-19-13-23-21(31-19)25-18-7-3-6-17(22)24-18/h2-7,12-13H,8-11H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229109 (2-cyano-N-(2-methyl-5-(2-(pyridin-2-ylamino)thiazo...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1NC(=O)CC#N Show InChI InChI=1S/C18H15N5OS2/c1-12-5-6-13(10-14(12)22-16(24)7-8-19)25-17-11-21-18(26-17)23-15-4-2-3-9-20-15/h2-6,9-11H,7H2,1H3,(H,22,24)(H,20,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229106 (CHEMBL403342 | N-(2-cyanoethyl)-2-methyl-5-(2-(pyr...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)NCCC#N Show InChI InChI=1S/C19H17N5OS2/c1-13-6-7-14(11-15(13)18(25)22-10-4-8-20)26-17-12-23-19(27-17)24-16-5-2-3-9-21-16/h2-3,5-7,9,11-12H,4,10H2,1H3,(H,22,25)(H,21,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229112 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)NCCC#N Show InChI InChI=1S/C19H16BrN5OS2/c1-12-6-7-13(10-14(12)18(26)22-9-3-8-21)27-17-11-23-19(28-17)25-16-5-2-4-15(20)24-16/h2,4-7,10-11H,3,9H2,1H3,(H,22,26)(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229105 (1-(4-(2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-y...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C22H23N5O2S2/c1-15-6-7-17(13-18(15)21(29)27-11-9-26(10-12-27)16(2)28)30-20-14-24-22(31-20)25-19-5-3-4-8-23-19/h3-8,13-14H,9-12H2,1-2H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229091 (2-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC(N)=O)CC1 Show InChI InChI=1S/C22H23BrN6O2S2/c1-14-5-6-15(11-16(14)21(31)29-9-7-28(8-10-29)13-18(24)30)32-20-12-25-22(33-20)27-19-4-2-3-17(23)26-19/h2-6,11-12H,7-10,13H2,1H3,(H2,24,30)(H,25,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229111 ((2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCNCC1 Show InChI InChI=1S/C20H21N5OS2/c1-14-5-6-15(12-16(14)19(26)25-10-8-21-9-11-25)27-18-13-23-20(28-18)24-17-4-2-3-7-22-17/h2-7,12-13,21H,8-11H2,1H3,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50229085 ((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50229101 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CNCCN(C)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C20H22BrN5OS2/c1-13-7-8-14(11-15(13)19(27)26(3)10-9-22-2)28-18-12-23-20(29-18)25-17-6-4-5-16(21)24-17/h4-8,11-12,22H,9-10H2,1-3H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229114 (2-methyl-N-(2-(methylamino)ethyl)-5-(2-(pyridin-2-...) Show SMILES CNCCNC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C19H21N5OS2/c1-13-6-7-14(11-15(13)18(25)22-10-9-20-2)26-17-12-23-19(27-17)24-16-5-3-4-8-21-16/h3-8,11-12,20H,9-10H2,1-2H3,(H,22,25)(H,21,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229097 (CHEMBL254688 | methyl 4-(2-methyl-5-(2-(pyridin-2-...) Show SMILES COC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C22H23N5O3S2/c1-15-6-7-16(31-19-14-24-21(32-19)25-18-5-3-4-8-23-18)13-17(15)20(28)26-9-11-27(12-10-26)22(29)30-2/h3-8,13-14H,9-12H2,1-2H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50229085 ((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229115 ((5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-...) Show SMILES CCN1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C22H24BrN5OS2/c1-3-27-9-11-28(12-10-27)21(29)17-13-16(8-7-15(17)2)30-20-14-24-22(31-20)26-19-6-4-5-18(23)25-19/h4-8,13-14H,3,9-12H2,1-2H3,(H,24,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50186482 (1-(4-(3-(2-(pyridin-2-ylamino)thiazol-5-ylthio)ben...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(Sc2cnc(Nc3ccccn3)s2)c1 Show InChI InChI=1S/C21H21N5O2S2/c1-15(27)25-9-11-26(12-10-25)20(28)16-5-4-6-17(13-16)29-19-14-23-21(30-19)24-18-7-2-3-8-22-18/h2-8,13-14H,9-12H2,1H3,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229110 (CHEMBL254062 | N-(2-acetamidoethyl)-2-methyl-5-(2-...) Show SMILES CC(=O)NCCNC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C20H21N5O2S2/c1-13-6-7-15(11-16(13)19(27)23-10-9-21-14(2)26)28-18-12-24-20(29-18)25-17-5-3-4-8-22-17/h3-8,11-12H,9-10H2,1-2H3,(H,21,26)(H,23,27)(H,22,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50229087 ((S)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50229083 (2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC1)C(=O)CN Show InChI InChI=1S/C22H23BrN6O2S2/c1-14-5-6-15(11-16(14)21(31)29-9-7-28(8-10-29)19(30)12-24)32-20-13-25-22(33-20)27-18-4-2-3-17(23)26-18/h2-6,11,13H,7-10,12,24H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50229082 (1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C22H22BrN5O2S2/c1-14-6-7-16(12-17(14)21(30)28-10-8-27(9-11-28)15(2)29)31-20-13-24-22(32-20)26-19-5-3-4-18(23)25-19/h3-7,12-13H,8-11H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50229087 ((S)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229096 (1-(4-(3-(2-(5-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(Sc2cnc(Nc3ccc(Br)cn3)s2)c1 Show InChI InChI=1S/C21H20BrN5O2S2/c1-14(28)26-7-9-27(10-8-26)20(29)15-3-2-4-17(11-15)30-19-13-24-21(31-19)25-18-6-5-16(22)12-23-18/h2-6,11-13H,7-10H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50229083 (2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC1)C(=O)CN Show InChI InChI=1S/C22H23BrN6O2S2/c1-14-5-6-15(11-16(14)21(31)29-9-7-28(8-10-29)19(30)12-24)32-20-13-25-22(33-20)27-18-4-2-3-17(23)26-18/h2-6,11,13H,7-10,12,24H2,1H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50229085 ((R)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229102 (1-(4-(2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-y...) Show SMILES CC(=O)N1CCN(Cc2cc(Sc3cnc(Nc4ccccn4)s3)ccc2C)CC1 Show InChI InChI=1S/C22H25N5OS2/c1-16-6-7-19(13-18(16)15-26-9-11-27(12-10-26)17(2)28)29-21-14-24-22(30-21)25-20-5-3-4-8-23-20/h3-8,13-14H,9-12,15H2,1-2H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229084 (CHEMBL442438 | N-(2-hydroxyethyl)-2-methyl-5-(2-(p...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)NCCO Show InChI InChI=1S/C18H18N4O2S2/c1-12-5-6-13(10-14(12)17(24)20-8-9-23)25-16-11-21-18(26-16)22-15-4-2-3-7-19-15/h2-7,10-11,23H,8-9H2,1H3,(H,20,24)(H,19,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229089 (2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio)...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(N)=O Show InChI InChI=1S/C16H14N4OS2/c1-10-5-6-11(8-12(10)15(17)21)22-14-9-19-16(23-14)20-13-4-2-3-7-18-13/h2-9H,1H3,(H2,17,21)(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229104 ((2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-ylthio...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C21H23N5O3S3/c1-15-6-7-16(30-19-14-23-21(31-19)24-18-5-3-4-8-22-18)13-17(15)20(27)25-9-11-26(12-10-25)32(2,28)29/h3-8,13-14H,9-12H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50229101 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CNCCN(C)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C20H22BrN5OS2/c1-13-7-8-14(11-15(13)19(27)26(3)10-9-22-2)28-18-12-23-20(29-18)25-17-6-4-5-16(21)24-17/h4-8,11-12,22H,9-10H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50229083 (2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiaz...) Show SMILES Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(CC1)C(=O)CN Show InChI InChI=1S/C22H23BrN6O2S2/c1-14-5-6-15(11-16(14)21(31)29-9-7-28(8-10-29)19(30)12-24)32-20-13-25-22(33-20)27-18-4-2-3-17(23)26-18/h2-6,11,13H,7-10,12,24H2,1H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50229087 ((S)-2-amino-1-(4-(5-(2-(6-bromopyridin-2-ylamino)t...) Show SMILES C[C@H](N)C(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C23H25BrN6O2S2/c1-14-6-7-16(33-20-13-26-23(34-20)28-19-5-3-4-18(24)27-19)12-17(14)22(32)30-10-8-29(9-11-30)21(31)15(2)25/h3-7,12-13,15H,8-11,25H2,1-2H3,(H,26,27,28)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50229082 (1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C22H22BrN5O2S2/c1-14-6-7-16(12-17(14)21(30)28-10-8-27(9-11-28)15(2)29)31-20-13-24-22(32-20)26-19-5-3-4-18(23)25-19/h3-7,12-13H,8-11H2,1-2H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50229082 (1-(4-(5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C22H22BrN5O2S2/c1-14-6-7-16(12-17(14)21(30)28-10-8-27(9-11-28)15(2)29)31-20-13-24-22(32-20)26-19-5-3-4-18(23)25-19/h3-7,12-13H,8-11H2,1-2H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50229101 (5-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylthio)-N...) Show SMILES CNCCN(C)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1C Show InChI InChI=1S/C20H22BrN5OS2/c1-13-7-8-14(11-15(13)19(27)26(3)10-9-22-2)28-18-12-23-20(29-18)25-17-6-4-5-16(21)24-17/h4-8,11-12,22H,9-10H2,1-3H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229094 (1-(4-(2-methyl-5-(2-(pyridin-2-ylamino)thiazol-5-y...) Show SMILES CC(=O)N1CCCN(CC1)C(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C23H25N5O2S2/c1-16-7-8-18(31-21-15-25-23(32-21)26-20-6-3-4-9-24-20)14-19(16)22(30)28-11-5-10-27(12-13-28)17(2)29/h3-4,6-9,14-15H,5,10-13H2,1-2H3,(H,24,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229092 (1-(4-(3-(2-(6-methylpyridin-2-ylamino)thiazol-5-yl...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cccc(Sc2cnc(Nc3cccc(C)n3)s2)c1 Show InChI InChI=1S/C22H23N5O2S2/c1-15-5-3-8-19(24-15)25-22-23-14-20(31-22)30-18-7-4-6-17(13-18)21(29)27-11-9-26(10-12-27)16(2)28/h3-8,13-14H,9-12H2,1-2H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229093 (2-methyl-N-(prop-2-ynyl)-5-(2-(pyridin-2-ylamino)t...) Show SMILES Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)NCC#C Show InChI InChI=1S/C19H16N4OS2/c1-3-9-21-18(24)15-11-14(8-7-13(15)2)25-17-12-22-19(26-17)23-16-6-4-5-10-20-16/h1,4-8,10-12H,9H2,2H3,(H,21,24)(H,20,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229108 (1-(4-(4-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1 Show InChI InChI=1S/C21H20BrN5O2S2/c1-14(28)26-9-11-27(12-10-26)20(29)15-5-7-16(8-6-15)30-19-13-23-21(31-19)25-18-4-2-3-17(22)24-18/h2-8,13H,9-12H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229103 (1-(4-(2-(2-(6-bromopyridin-2-ylamino)thiazol-5-ylt...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1ccccc1Sc1cnc(Nc2cccc(Br)n2)s1 Show InChI InChI=1S/C21H20BrN5O2S2/c1-14(28)26-9-11-27(12-10-26)20(29)15-5-2-3-6-16(15)30-19-13-23-21(31-19)25-18-8-4-7-17(22)24-18/h2-8,13H,9-12H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229107 (CHEMBL253857 | N-isopropyl-2-methyl-5-(2-(pyridin-...) Show SMILES CC(C)NC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C19H20N4OS2/c1-12(2)22-18(24)15-10-14(8-7-13(15)3)25-17-11-21-19(26-17)23-16-6-4-5-9-20-16/h4-12H,1-3H3,(H,22,24)(H,20,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229088 (CHEMBL401374 | N-ethyl-2-methyl-5-(2-(pyridin-2-yl...) Show SMILES CCNC(=O)c1cc(Sc2cnc(Nc3ccccn3)s2)ccc1C Show InChI InChI=1S/C18H18N4OS2/c1-3-19-17(23)14-10-13(8-7-12(14)2)24-16-11-21-18(25-16)22-15-6-4-5-9-20-15/h4-11H,3H2,1-2H3,(H,19,23)(H,20,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229098 (1-(4-(5-(2-aminothiazol-5-ylthio)-2-methylbenzoyl)...) Show SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(Sc2cnc(N)s2)ccc1C Show InChI InChI=1S/C17H20N4O2S2/c1-11-3-4-13(24-15-10-19-17(18)25-15)9-14(11)16(23)21-7-5-20(6-8-21)12(2)22/h3-4,9-10H,5-8H2,1-2H3,(H2,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50229099 (CHEMBL253855 | N-(5-(3-(1-acetylpiperazine-4-carbo...) Show SMILES CC(=O)Nc1ncc(Sc2ccc(C)c(c2)C(=O)N2CCN(CC2)C(C)=O)s1 Show InChI InChI=1S/C19H22N4O3S2/c1-12-4-5-15(27-17-11-20-19(28-17)21-13(2)24)10-16(12)18(26)23-8-6-22(7-9-23)14(3)25/h4-5,10-11H,6-9H2,1-3H3,(H,20,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of TrkA				Bioorg Med Chem Lett 18: 634-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.076 BindingDB Entry DOI: 10.7270/Q2JD4WJ5
					More data for this Ligand-Target Pair

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