Compile Data Set for Download or QSAR

Found 59 hits Enz. Inhib. hit(s) with all data for entry = 50028770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258344 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(pyrrolidi...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H27N5O/c1-19-23-10-11-30-26(23)9-8-25(19)31-27-21(16-28)17-29-18-24(27)20-4-6-22(7-5-20)33-15-14-32-12-2-3-13-32/h4-11,17-18,30H,2-3,12-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258795 (5-(3,4-dimethoxyphenyl)-4-(4-fluoro-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1F Show InChI InChI=1S/C22H17FN4O2/c1-28-19-6-3-13(9-20(19)29-2)16-12-25-11-14(10-24)22(16)27-18-5-4-17-15(21(18)23)7-8-26-17/h3-9,11-12,26H,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258798 (5-(4-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-18-9-10-25-21(18)8-7-20(14)26-22-16(11-23)12-24-13-19(22)15-3-5-17(27-2)6-4-15/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258388 (5-(4-(2-(2-(dimethylamino)ethylamino)ethoxy)phenyl...) Show SMILES CN(C)CCNCCOc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C27H30N6O/c1-19-23-10-11-31-26(23)9-8-25(19)32-27-21(16-28)17-30-18-24(27)20-4-6-22(7-5-20)34-15-13-29-12-14-33(2)3/h4-11,17-18,29,31H,12-15H2,1-3H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258384 (5-(3,4-dimethoxyphenyl)-4-(4-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C23H20N4O2/c1-14-17-8-9-26-20(17)6-5-19(14)27-23-16(11-24)12-25-13-18(23)15-4-7-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258822 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-24-9-10-31-27(24)8-7-26(20)32-28-22(17-29)18-30-19-25(28)21-3-5-23(6-4-21)35-16-15-34-13-11-33(2)12-14-34/h3-10,18-19,31H,11-16H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258346 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-(pyrrol...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCC(CC3)N3CCCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C32H36N6O/c1-23-28-10-13-35-31(28)9-8-30(23)36-32-25(20-33)21-34-22-29(32)24-4-6-27(7-5-24)39-19-18-37-16-11-26(12-17-37)38-14-2-3-15-38/h4-10,13,21-22,26,35H,2-3,11-12,14-19H2,1H3,(H,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258387 (5-(3,4-dimethoxyphenyl)-4-(6-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc2cc[nH]c2cc1C Show InChI InChI=1S/C23H20N4O2/c1-14-8-20-16(6-7-26-20)9-19(14)27-23-17(11-24)12-25-13-18(23)15-4-5-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258794 (5-(3,4-dimethoxyphenyl)-4-(4-methoxy-1H-indol-5-yl...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1OC Show InChI InChI=1S/C23H20N4O3/c1-28-20-7-4-14(10-21(20)29-2)17-13-25-12-15(11-24)22(17)27-19-6-5-18-16(8-9-26-18)23(19)30-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM29816 (4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12 Show InChI InChI=1S/C22H18N4O2/c1-27-20-7-6-14(10-21(20)28-2)17-13-24-12-15(11-23)22(17)26-19-5-3-4-18-16(19)8-9-25-18/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258345 (5-(4-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)p...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C29H32N6O2/c1-21-25-8-9-32-28(25)7-6-27(21)33-29-23(18-30)19-31-20-26(29)22-2-4-24(5-3-22)37-17-15-35-12-10-34(11-13-35)14-16-36/h2-9,19-20,32,36H,10-17H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258390 (4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-11-13-33(14-12-32)15-16-34-22-7-5-20(6-8-22)24-19-29-18-21(17-28)27(24)31-26-4-2-3-25-23(26)9-10-30-25/h2-10,18-19,30H,11-16H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258388 (5-(4-(2-(2-(dimethylamino)ethylamino)ethoxy)phenyl...) Show SMILES CN(C)CCNCCOc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C27H30N6O/c1-19-23-10-11-31-26(23)9-8-25(19)32-27-21(16-28)17-30-18-24(27)20-4-6-22(7-5-20)34-15-13-29-12-14-33(2)3/h4-11,17-18,29,31H,12-15H2,1-3H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258389 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(3-(piperazin...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C29H32N6O/c1-21-25-10-11-32-28(25)9-8-27(21)33-29-23(18-30)19-31-20-26(29)22-4-6-24(7-5-22)36-17-3-12-35-15-13-34(2)14-16-35/h4-11,19-20,32H,3,12-17H2,1-2H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258821 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-morpholino...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCOCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H27N5O2/c1-19-23-8-9-30-26(23)7-6-25(19)31-27-21(16-28)17-29-18-24(27)20-2-4-22(5-3-20)34-15-12-32-10-13-33-14-11-32/h2-9,17-18,30H,10-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258797 (4-(4-methyl-1H-indol-5-ylamino)-5-phenylnicotinoni...) Show SMILES Cc1c(Nc2c(cncc2-c2ccccc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C21H16N4/c1-14-17-9-10-24-20(17)8-7-19(14)25-21-16(11-22)12-23-13-18(21)15-5-3-2-4-6-15/h2-10,12-13,24H,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258344 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(pyrrolidi...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H27N5O/c1-19-23-10-11-30-26(23)9-8-25(19)31-27-21(16-28)17-29-18-24(27)20-4-6-22(7-5-20)33-15-14-32-12-2-3-13-32/h4-11,17-18,30H,2-3,12-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258345 (5-(4-(2-(4-(2-hydroxyethyl)piperazin-1-yl)ethoxy)p...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C29H32N6O2/c1-21-25-8-9-32-28(25)7-6-27(21)33-29-23(18-30)19-31-20-26(29)22-2-4-24(5-3-22)37-17-15-35-12-10-34(11-13-35)14-16-36/h2-9,19-20,32,36H,10-17H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258346 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-(pyrrol...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCC(CC3)N3CCCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C32H36N6O/c1-23-28-10-13-35-31(28)9-8-30(23)36-32-25(20-33)21-34-22-29(32)24-4-6-27(7-5-24)39-19-18-37-16-11-26(12-17-37)38-14-2-3-15-38/h4-10,13,21-22,26,35H,2-3,11-12,14-19H2,1H3,(H,34,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258823 (4-(6-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cc3cc[nH]c3cc2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-15-27-22(7-8-31-27)16-26(20)32-28-23(17-29)18-30-19-25(28)21-3-5-24(6-4-21)35-14-13-34-11-9-33(2)10-12-34/h3-8,15-16,18-19,31H,9-14H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258819 (5-(3-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1cccc(c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-18-8-9-25-21(18)7-6-20(14)26-22-16(11-23)12-24-13-19(22)15-4-3-5-17(10-15)27-2/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258390 (4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-11-13-33(14-12-32)15-16-34-22-7-5-20(6-8-22)24-19-29-18-21(17-28)27(24)31-26-4-2-3-25-23(26)9-10-30-25/h2-10,18-19,30H,11-16H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258822 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-24-9-10-31-27(24)8-7-26(20)32-28-22(17-29)18-30-19-25(28)21-3-5-23(6-4-21)35-16-15-34-13-11-33(2)12-14-34/h3-10,18-19,31H,11-16H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50258822 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-24-9-10-31-27(24)8-7-26(20)32-28-22(17-29)18-30-19-25(28)21-3-5-23(6-4-21)35-16-15-34-13-11-33(2)12-14-34/h3-10,18-19,31H,11-16H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCepsilon by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258385 (5-(3,4-dimethoxyphenyl)-4-(4-ethyl-1H-indol-5-ylam...) Show SMILES CCc1c(Nc2c(cncc2-c2ccc(OC)c(OC)c2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N4O2/c1-4-17-18-9-10-27-20(18)6-7-21(17)28-24-16(12-25)13-26-14-19(24)15-5-8-22(29-2)23(11-15)30-3/h5-11,13-14,27H,4H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM29816 (4-indolylamino-5-phenyl-3-pyridinecarbonitrile, 1c...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2[nH]ccc12 Show InChI InChI=1S/C22H18N4O2/c1-27-20-7-6-14(10-21(20)28-2)17-13-24-12-15(11-23)22(17)26-19-5-3-4-18-16(19)8-9-25-18/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258797 (4-(4-methyl-1H-indol-5-ylamino)-5-phenylnicotinoni...) Show SMILES Cc1c(Nc2c(cncc2-c2ccccc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C21H16N4/c1-14-17-9-10-24-20(17)8-7-19(14)25-21-16(11-22)12-23-13-18(21)15-5-3-2-4-6-15/h2-10,12-13,24H,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258795 (5-(3,4-dimethoxyphenyl)-4-(4-fluoro-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1F Show InChI InChI=1S/C22H17FN4O2/c1-28-19-6-3-13(9-20(19)29-2)16-12-25-11-14(10-24)22(16)27-18-5-4-17-15(21(18)23)7-8-26-17/h3-9,11-12,26H,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM25558 (4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H18N4O2/c1-27-20-6-3-14(10-21(20)28-2)18-13-24-12-16(11-23)22(18)26-17-4-5-19-15(9-17)7-8-25-19/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258391 (4-(1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-10-12-33(13-11-32)14-15-34-24-5-2-20(3-6-24)25-19-29-18-22(17-28)27(25)31-23-4-7-26-21(16-23)8-9-30-26/h2-9,16,18-19,30H,10-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258384 (5-(3,4-dimethoxyphenyl)-4-(4-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C23H20N4O2/c1-14-17-8-9-26-20(17)6-5-19(14)27-23-16(11-24)12-25-13-18(23)15-4-7-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258820 (5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1ccccc1-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-16-9-10-25-20(16)8-7-19(14)26-22-15(11-23)12-24-13-18(22)17-5-3-4-6-21(17)27-2/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258798 (5-(4-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1ccc(cc1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-18-9-10-25-21(18)8-7-20(14)26-22-16(11-23)12-24-13-19(22)15-3-5-17(27-2)6-4-15/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258389 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(3-(piperazin...) Show SMILES CN1CCN(CCCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C29H32N6O/c1-21-25-10-11-32-28(25)9-8-27(21)33-29-23(18-30)19-31-20-26(29)22-4-6-24(7-5-22)36-17-3-12-35-15-13-34(2)14-16-35/h4-11,19-20,32H,3,12-17H2,1-2H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258386 (5-(3,4-dimethoxyphenyl)-4-(7-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc(C)c2[nH]ccc2c1 Show InChI InChI=1S/C23H20N4O2/c1-14-8-18(9-16-6-7-26-22(14)16)27-23-17(11-24)12-25-13-19(23)15-4-5-20(28-2)21(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258823 (4-(6-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cc3cc[nH]c3cc2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-15-27-22(7-8-31-27)16-26(20)32-28-23(17-29)18-30-19-25(28)21-3-5-24(6-4-21)35-14-13-34-11-9-33(2)10-12-34/h3-8,15-16,18-19,31H,9-14H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258821 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-morpholino...) Show SMILES Cc1c(Nc2c(cncc2-c2ccc(OCCN3CCOCC3)cc2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H27N5O2/c1-19-23-8-9-30-26(23)7-6-25(19)31-27-21(16-28)17-29-18-24(27)20-2-4-22(5-3-20)34-15-12-32-10-13-33-14-11-32/h2-9,17-18,30H,10-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258391 (4-(1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-10-12-33(13-11-32)14-15-34-24-5-2-20(3-6-24)25-19-29-18-22(17-28)27(25)31-23-4-7-26-21(16-23)8-9-30-26/h2-9,16,18-19,30H,10-15H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258819 (5-(3-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1cccc(c1)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-18-8-9-25-21(18)7-6-20(14)26-22-16(11-23)12-24-13-19(22)15-4-3-5-17(10-15)27-2/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258796 (5-(3,4-dimethoxyphenyl)-4-(1,4-dimethyl-1H-indol-5...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2n(C)ccc2c1C Show InChI InChI=1S/C24H22N4O2/c1-15-18-9-10-28(2)21(18)7-6-20(15)27-24-17(12-25)13-26-14-19(24)16-5-8-22(29-3)23(11-16)30-4/h5-11,13-14H,1-4H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258341 (4-((1H-indol-5-yl)(methyl)amino)-5-(3,4-dimethoxyp...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1N(C)c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C23H20N4O2/c1-27(18-5-6-20-16(10-18)8-9-26-20)23-17(12-24)13-25-14-19(23)15-4-7-21(28-2)22(11-15)29-3/h4-11,13-14,26H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258387 (5-(3,4-dimethoxyphenyl)-4-(6-methyl-1H-indol-5-yla...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cc2cc[nH]c2cc1C Show InChI InChI=1S/C23H20N4O2/c1-14-8-20-16(6-7-26-20)9-19(14)27-23-17(11-24)12-25-13-18(23)15-4-5-21(28-2)22(10-15)29-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258820 (5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...) Show SMILES COc1ccccc1-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C Show InChI InChI=1S/C22H18N4O/c1-14-16-9-10-25-20(16)8-7-19(14)26-22-15(11-23)12-24-13-18(22)17-5-3-4-6-21(17)27-2/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM25558 (4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H18N4O2/c1-27-20-6-3-14(10-21(20)28-2)18-13-24-12-16(11-23)22(18)26-17-4-5-19-15(9-17)7-8-25-19/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258794 (5-(3,4-dimethoxyphenyl)-4-(4-methoxy-1H-indol-5-yl...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1OC Show InChI InChI=1S/C23H20N4O3/c1-28-20-7-4-14(10-21(20)29-2)17-13-25-12-15(11-24)22(17)27-19-6-5-18-16(8-9-26-18)23(19)30-3/h4-10,12-13,26H,1-3H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C eta type (Homo sapiens (Human))	BDBM50258822 (4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-24-9-10-31-27(24)8-7-26(20)32-28-22(17-29)18-30-19-25(28)21-3-5-23(6-4-21)35-16-15-34-13-11-33(2)12-14-34/h3-10,18-19,31H,11-16H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCeta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258793 (4-(1H-indol-7-ylamino)-5-(3,4-dimethoxyphenyl)nico...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1cccc2cc[nH]c12 Show InChI InChI=1S/C22H18N4O2/c1-27-19-7-6-15(10-20(19)28-2)17-13-24-12-16(11-23)21(17)26-18-5-3-4-14-8-9-25-22(14)18/h3-10,12-13,25H,1-2H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258385 (5-(3,4-dimethoxyphenyl)-4-(4-ethyl-1H-indol-5-ylam...) Show SMILES CCc1c(Nc2c(cncc2-c2ccc(OC)c(OC)c2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N4O2/c1-4-17-18-9-10-27-20(18)6-7-21(17)28-24-16(12-25)13-26-14-19(24)15-5-8-22(29-2)23(11-15)30-3/h5-11,13-14,27H,4H2,1-3H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258796 (5-(3,4-dimethoxyphenyl)-4-(1,4-dimethyl-1H-indol-5...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2n(C)ccc2c1C Show InChI InChI=1S/C24H22N4O2/c1-15-18-9-10-28(2)21(18)7-6-20(15)27-24-17(12-25)13-26-14-19(24)16-5-8-22(29-3)23(11-16)30-4/h5-11,13-14H,1-4H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258343 (5-(3,4-dimethoxyphenyl)-4-(1H-indol-5-yl)nicotinon...) Show SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C22H17N3O2/c1-26-20-6-4-14(10-21(20)27-2)18-13-24-12-17(11-23)22(18)16-3-5-19-15(9-16)7-8-25-19/h3-10,12-13,25H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair

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