Compile Data Set for Download or QSAR

Found 176 hits Enz. Inhib. hit(s) with all data for entry = 657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285736 (US10080744, Example 3/4) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H27Cl2F3N4O5S2/c1-4-16(25(28,29)30)34-41(37,38)15-9-8-13(18(26)19(15)27)20-14(10-12-6-5-7-12)31-22(40-20)21-33-32-17(39-21)11-24(2,3)23(35)36/h8-9,12,16,34H,4-7,10-11H2,1-3H3,(H,35,36)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285758 (US10080744, Example 3/25 | US10080744, Example 4/1) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C26H28F6N4O5S2/c1-4-16(26(30,31)32)36-43(39,40)15-9-8-13(18(19(15)27)21(28)29)20-14(10-12-6-5-7-12)33-23(42-20)22-35-34-17(41-22)11-25(2,3)24(37)38/h8-9,12,16,21,36H,4-7,10-11H2,1-3H3,(H,37,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285762 (US10080744, Example 3/29) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC(C)(C)C2)-c2nnc(CC(C)(C)C(O)=O)o2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H29Cl2F3N4O5S2/c1-12(26(29,30)31)35-42(38,39)16-7-6-14(18(27)19(16)28)20-15(8-13-9-24(2,3)10-13)32-22(41-20)21-34-33-17(40-21)11-25(4,5)23(36)37/h6-7,12-13,35H,8-11H2,1-5H3,(H,36,37)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285753 (US10080744, Example 3/20) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)OC=O)o2)c2ccccc12)C(F)(F)F |r| Show InChI InChI=1S/C30H33F3N4O5S2/c1-18(30(31,32)33)37-44(39,40)24-14-13-22(20-11-7-8-12-21(20)24)26-23(15-19-9-5-4-6-10-19)34-28(43-26)27-36-35-25(42-27)16-29(2,3)41-17-38/h7-8,11-14,17-19,37H,4-6,9-10,15-16H2,1-3H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285771 (US10080744, Example 3/38) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C27H30F6N4O5S2/c1-4-17(27(31,32)33)37-44(40,41)16-10-9-14(19(20(16)28)22(29)30)21-15(11-13-7-5-6-8-13)34-24(43-21)23-36-35-18(42-23)12-26(2,3)25(38)39/h9-10,13,17,22,37H,4-8,11-12H2,1-3H3,(H,38,39)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285799 (US10080744, Example 11/10) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2(CCC2)OC)-c2noc(CC(C)(C)OC=O)n2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H29Cl2F3N4O6S2/c1-5-17(26(29,30)31)35-43(37,38)16-8-7-14(19(27)20(16)28)21-15(11-25(39-4)9-6-10-25)32-23(42-21)22-33-18(41-34-22)12-24(2,3)40-13-36/h7-8,13,17,35H,5-6,9-12H2,1-4H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285802 (US10080744, Example 12/1) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CN2CCCC(F)(F)C2)-c2noc(CC(C)(C)OC=O)n2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H28Cl2F5N5O5S2/c1-4-17(26(31,32)33)37-45(40,41)16-7-6-14(19(27)20(16)28)21-15(11-38-9-5-8-25(29,30)12-38)34-23(44-21)22-35-18(43-36-22)10-24(2,3)42-13-39/h6-7,13,17,37H,4-5,8-12H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285733 (US10080744, Example 3/1) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12 Show InChI InChI=1S/C31H38N4O5S2/c1-30(2,3)35-42(38,39)24-16-15-22(20-13-9-10-14-21(20)24)26-23(17-19-11-7-6-8-12-19)32-28(41-26)27-34-33-25(40-27)18-31(4,5)29(36)37/h9-10,13-16,19,35H,6-8,11-12,17-18H2,1-5H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285759 (US10080744, Example 3/26) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C28H32F6N4O5S2/c1-4-18(28(32,33)34)38-45(41,42)17-11-10-15(20(21(17)29)23(30)31)22-16(12-14-8-6-5-7-9-14)35-25(44-22)24-37-36-19(43-24)13-27(2,3)26(39)40/h10-11,14,18,23,38H,4-9,12-13H2,1-3H3,(H,39,40)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285763 (US10080744, Example 3/30) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC(F)(F)C2)-c2nnc(CC(C)(C)C(O)=O)o2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H25Cl2F5N4O5S2/c1-4-15(25(30,31)32)36-43(39,40)14-6-5-12(17(26)18(14)27)19-13(7-11-8-24(28,29)9-11)33-21(42-19)20-35-34-16(41-20)10-23(2,3)22(37)38/h5-6,11,15,36H,4,7-10H2,1-3H3,(H,37,38)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285789 (US10080744, Example 11) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2noc(CC(C)(C)OC=O)n2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C24H25Cl2F3N4O5S2/c1-12(24(27,28)29)33-40(35,36)16-8-7-14(18(25)19(16)26)20-15(9-13-5-4-6-13)30-22(39-20)21-31-17(38-32-21)10-23(2,3)37-11-34/h7-8,11-13,33H,4-6,9-10H2,1-3H3/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285798 (US10080744, Example 11/9) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCCCC1)-c1noc(CC(C)(C)OC=O)n1)C(F)(F)F |r| Show InChI InChI=1S/C31H37F3N4O4S/c1-18(31(32,33)34)35-27(40)21-13-20(14-22(15-21)30(4)10-11-30)25-23(12-19-8-6-5-7-9-19)36-28(43-25)26-37-24(42-38-26)16-29(2,3)41-17-39/h13-15,17-19H,5-12,16H2,1-4H3,(H,35,40)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285811 (US10080744, Example 15) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cccc(CC(C)(C)OC=O)c2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C28H29Cl2F3N2O4S2/c1-16(28(31,32)33)35-41(37,38)22-11-10-20(23(29)24(22)30)25-21(13-17-6-4-7-17)34-26(40-25)19-9-5-8-18(12-19)14-27(2,3)39-15-36/h5,8-12,15-17,35H,4,6-7,13-14H2,1-3H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285800 (US10080744, Example 11/11) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2noc(CC(C)(C)C(O)=O)n2)c(C(F)F)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H26ClF5N4O5S2/c1-11(25(29,30)31)35-42(38,39)15-8-7-13(17(18(15)26)20(27)28)19-14(9-12-5-4-6-12)32-22(41-19)21-33-16(40-34-21)10-24(2,3)23(36)37/h7-8,11-12,20,35H,4-6,9-10H2,1-3H3,(H,36,37)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285742 (US10080744, Example 3/9) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)OC=O)o2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C24H25Cl2F3N4O5S2/c1-12(24(27,28)29)33-40(35,36)16-8-7-14(18(25)19(16)26)20-15(9-13-5-4-6-13)30-22(39-20)21-32-31-17(38-21)10-23(2,3)37-11-34/h7-8,11-13,33H,4-6,9-10H2,1-3H3/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285795 (US10080744, Example 11/6) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2noc(CC(C)(C)OC=O)n2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C26H28F6N4O5S2/c1-4-17(26(30,31)32)36-43(38,39)16-9-8-14(19(20(16)27)22(28)29)21-15(10-13-6-5-7-13)33-24(42-21)23-34-18(41-35-23)11-25(2,3)40-12-37/h8-9,12-13,17,22,36H,4-7,10-11H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285774 (US10080744, Example 3/41) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(F)c1C(F)F)C(F)(F)F |r| Show InChI InChI=1S/C27H30F6N4O5S2/c1-4-17(27(31,32)33)37-44(40,41)16-10-9-14(20(28)19(16)22(29)30)21-15(11-13-7-5-6-8-13)34-24(43-21)23-36-35-18(42-23)12-26(2,3)25(38)39/h9-10,13,17,22,37H,4-8,11-12H2,1-3H3,(H,38,39)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285769 (US10080744, Example 3/36) Show SMILES CC(C)(C)c1cc(cc(c1)C(O)(C(F)(F)F)C(F)(F)F)-c1sc(nc1CC1CCC1)-c1nnc(CC(C)(C)C(O)=O)o1 Show InChI InChI=1S/C28H31F6N3O4S/c1-24(2,3)16-10-15(11-17(12-16)26(40,27(29,30)31)28(32,33)34)20-18(9-14-7-6-8-14)35-22(42-20)21-37-36-19(41-21)13-25(4,5)23(38)39/h10-12,14,40H,6-9,13H2,1-5H3,(H,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285803 (US10080744, Example 12/2) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CN2CC(F)(F)C[C@@H]2C)-c2noc(CC(C)(C)OC=O)n2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H28Cl2F5N5O5S2/c1-5-17(26(31,32)33)37-45(40,41)16-7-6-14(19(27)20(16)28)21-15(10-38-11-25(29,30)8-13(38)2)34-23(44-21)22-35-18(43-36-22)9-24(3,4)42-12-39/h6-7,12-13,17,37H,5,8-11H2,1-4H3/t13-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285812 (US10080744, Example 16) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cccc(CC(C)(C)OC=O)n2)c2ccncc12)C(F)(F)F |r| Show InChI InChI=1S/C30H31F3N4O4S2/c1-18(30(31,32)33)37-43(39,40)26-11-10-22(21-12-13-34-16-23(21)26)27-25(14-19-6-4-7-19)36-28(42-27)24-9-5-8-20(35-24)15-29(2,3)41-17-38/h5,8-13,16-19,37H,4,6-7,14-15H2,1-3H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285779 (US10080744, Example 4/2) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CC(F)(F)C2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12)C(F)(F)F |r| Show InChI InChI=1S/C29H29F5N4O5S2/c1-4-21(29(32,33)34)38-45(41,42)20-10-9-18(16-7-5-6-8-17(16)20)23-19(11-15-12-28(30,31)13-15)35-25(44-23)24-37-36-22(43-24)14-27(2,3)26(39)40/h5-10,15,21,38H,4,11-14H2,1-3H3,(H,39,40)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285735 (US10080744, Example 3/3) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12)C(F)(F)F |r| Show InChI InChI=1S/C28H29F3N4O5S2/c1-15(28(29,30)31)35-42(38,39)21-12-11-19(17-9-4-5-10-18(17)21)23-20(13-16-7-6-8-16)32-25(41-23)24-34-33-22(40-24)14-27(2,3)26(36)37/h4-5,9-12,15-16,35H,6-8,13-14H2,1-3H3,(H,36,37)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285781 (US10080744, Example 6) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CN2CCCC(F)(F)C2)-c2nnc(o2)C(C)(C)O)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C24H26Cl2F5N5O4S2/c1-4-15(24(29,30)31)35-42(38,39)14-7-6-12(16(25)17(14)26)18-13(10-36-9-5-8-23(27,28)11-36)32-20(41-18)19-33-34-21(40-19)22(2,3)37/h6-7,15,35,37H,4-5,8-11H2,1-3H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285796 (US10080744, Example 11/7) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2noc(CC(C)(C)OC=O)n2)c(c1F)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C26H27F7N4O5S2/c1-4-17(25(28,29)30)37-44(39,40)16-9-8-14(19(20(16)27)26(31,32)33)21-15(10-13-6-5-7-13)34-23(43-21)22-35-18(42-36-22)11-24(2,3)41-12-38/h8-9,12-13,17,37H,4-7,10-11H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285765 (US10080744, Example 3/32) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2Cc2ccc(F)cc2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C28H25F7N4O5S2/c1-4-18(28(33,34)35)39-46(42,43)17-10-9-15(20(21(17)30)23(31)32)22-16(11-13-5-7-14(29)8-6-13)36-25(45-22)24-38-37-19(44-24)12-27(2,3)26(40)41/h5-10,18,23,39H,4,11-12H2,1-3H3,(H,40,41)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285730 (US10080744, Example 1/1) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(o2)C(C)(C)O)c2ccccc12 Show InChI InChI=1S/C29H36N4O4S2/c1-28(2,3)33-39(35,36)23-16-15-21(19-13-9-10-14-20(19)23)24-22(17-18-11-7-6-8-12-18)30-26(38-24)25-31-32-27(37-25)29(4,5)34/h9-10,13-16,18,33-34H,6-8,11-12,17H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The human Th17 assay tests the effect of RORγt modulatory compounds on IL-17 production by CD4 T cells under conditions which favor Th17 differe...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285773 (US10080744, Example 3/40) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H28ClF5N4O5S2/c1-12(26(30,31)32)36-43(39,40)16-9-8-14(18(19(16)27)21(28)29)20-15(10-13-6-4-5-7-13)33-23(42-20)22-35-34-17(41-22)11-25(2,3)24(37)38/h8-9,12-13,21,36H,4-7,10-11H2,1-3H3,(H,37,38)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285793 (US10080744, Example 11/4) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2noc(CC(C)(C)OC=O)n2)c(OC(F)(F)F)c1)C(F)(F)F |r| Show InChI InChI=1S/C27H30F6N4O6S2/c1-15(26(28,29)30)37-45(39,40)17-9-10-18(20(12-17)42-27(31,32)33)22-19(11-16-7-5-4-6-8-16)34-24(44-22)23-35-21(43-36-23)13-25(2,3)41-14-38/h9-10,12,14-16,37H,4-8,11,13H2,1-3H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285766 (US10080744, Example 3/33) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2Cc2ccc(F)cc2)-c2nnc(CC(C)(C)C(O)=O)o2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H22Cl2F4N4O5S2/c1-12(26(30,31)32)36-43(39,40)17-9-8-15(19(27)20(17)28)21-16(10-13-4-6-14(29)7-5-13)33-23(42-21)22-35-34-18(41-22)11-25(2,3)24(37)38/h4-9,12,36H,10-11H2,1-3H3,(H,37,38)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285810 (US10080744, Example 14) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cc(CC(C)(C)C)on2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H28Cl2F3N3O3S2/c1-13(25(28,29)30)33-38(34,35)19-9-8-16(20(26)21(19)27)22-17(10-14-6-5-7-14)31-23(37-22)18-11-15(36-32-18)12-24(2,3)4/h8-9,11,13-14,33H,5-7,10,12H2,1-4H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285757 (US10080744, Example 3/24) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C27H30F6N4O5S2/c1-13(27(31,32)33)37-44(40,41)17-10-9-15(19(20(17)28)22(29)30)21-16(11-14-7-5-4-6-8-14)34-24(43-21)23-36-35-18(42-23)12-26(2,3)25(38)39/h9-10,13-14,22,37H,4-8,11-12H2,1-3H3,(H,38,39)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285791 (US10080744, Example 11/2) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2noc(CC(C)(C)OC=O)n2)c2ccncc12)C(F)(F)F |r| Show InChI InChI=1S/C29H32F3N5O5S2/c1-17(29(30,31)32)37-44(39,40)23-10-9-20(19-11-12-33-15-21(19)23)25-22(13-18-7-5-4-6-8-18)34-27(43-25)26-35-24(42-36-26)14-28(2,3)41-16-38/h9-12,15-18,37H,4-8,13-14H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285746 (US10080744, Example 3/13) Show SMILES CC(C)Cc1nc(sc1-c1ccc(c(Cl)c1Cl)S(=O)(=O)N[C@@H](C)C(F)(F)F)-c1nnc(CC(C)(C)OC=O)o1 |r| Show InChI InChI=1S/C23H25Cl2F3N4O5S2/c1-11(2)8-14-19(38-21(29-14)20-31-30-16(37-20)9-22(4,5)36-10-33)13-6-7-15(18(25)17(13)24)39(34,35)32-12(3)23(26,27)28/h6-7,10-12,32H,8-9H2,1-5H3/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285775 (US10080744, Example 3/42) Show SMILES CC(C)(Cc1nnc(o1)-c1nc(Cc2ccc(F)cc2)c(s1)-c1ccc(cc1C(F)F)C(O)(C(F)(F)F)C(F)(F)F)C(O)=O Show InChI InChI=1S/C27H20F9N3O4S/c1-24(2,23(40)41)11-18-38-39-21(43-18)22-37-17(9-12-3-6-14(28)7-4-12)19(44-22)15-8-5-13(10-16(15)20(29)30)25(42,26(31,32)33)27(34,35)36/h3-8,10,20,42H,9,11H2,1-2H3,(H,40,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285790 (US10080744, Example 11/1) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2noc(CC(C)(C)OC=O)n2)c(OC(F)(F)F)c1)C(F)(F)F |r| Show InChI InChI=1S/C25H26F6N4O6S2/c1-13(24(26,27)28)35-43(37,38)15-7-8-16(18(10-15)40-25(29,30)31)20-17(9-14-5-4-6-14)32-22(42-20)21-33-19(41-34-21)11-23(2,3)39-12-36/h7-8,10,12-14,35H,4-6,9,11H2,1-3H3/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285792 (US10080744, Example 11/3) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2noc(CC(C)(C)OC=O)n2)c2cnccc12)C(F)(F)F |r| Show InChI InChI=1S/C29H32F3N5O5S2/c1-17(29(30,31)32)37-44(39,40)23-10-9-20(21-15-33-12-11-19(21)23)25-22(13-18-7-5-4-6-8-18)34-27(43-25)26-35-24(42-36-26)14-28(2,3)41-16-38/h9-12,15-18,37H,4-8,13-14H2,1-3H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285732 (US10080744, Example 3 | US10080744, Example 3/8b) Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(Cl)c1Cl Show InChI InChI=1S/C25H30Cl2N4O5S2/c1-24(2,3)31-38(34,35)16-10-9-14(18(26)19(16)27)20-15(11-13-7-6-8-13)28-22(37-20)21-30-29-17(36-21)12-25(4,5)23(32)33/h9-10,13,31H,6-8,11-12H2,1-5H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285768 (US10080744, Example 3/35) Show SMILES C[C@H](NC(=O)c1cc(cc(c1)C1(C)CC1)-c1sc(nc1CC1CCC1)-c1nnc(CC(C)(C)OC=O)o1)C(F)(F)F |r| Show InChI InChI=1S/C29H33F3N4O4S/c1-16(29(30,31)32)33-24(38)19-11-18(12-20(13-19)28(4)8-9-28)23-21(10-17-6-5-7-17)34-26(41-23)25-36-35-22(40-25)14-27(2,3)39-15-37/h11-13,15-17H,5-10,14H2,1-4H3,(H,33,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285758 (US10080744, Example 3/25 | US10080744, Example 4/1) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C26H28F6N4O5S2/c1-4-16(26(30,31)32)36-43(39,40)15-9-8-13(18(19(15)27)21(28)29)20-14(10-12-6-5-7-12)33-23(42-20)22-35-34-17(41-22)11-25(2,3)24(37)38/h8-9,12,16,21,36H,4-7,10-11H2,1-3H3,(H,37,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	25
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285815 (US10080744, Example 18) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cnc(CC(C)(C)C(O)=O)s2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H26Cl2F3N3O4S3/c1-12(25(28,29)30)33-40(36,37)17-8-7-14(19(26)20(17)27)21-15(9-13-5-4-6-13)32-22(39-21)16-11-31-18(38-16)10-24(2,3)23(34)35/h7-8,11-13,33H,4-6,9-10H2,1-3H3,(H,34,35)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285754 (US10080744, Example 3/21) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)OC=O)o2)c(OC(F)(F)F)c1)C(F)(F)F |r| Show InChI InChI=1S/C27H30F6N4O6S2/c1-15(26(28,29)30)37-45(39,40)17-9-10-18(20(12-17)43-27(31,32)33)22-19(11-16-7-5-4-6-8-16)34-24(44-22)23-36-35-21(42-23)13-25(2,3)41-14-38/h9-10,12,14-16,37H,4-8,11,13H2,1-3H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285758 (US10080744, Example 3/25 | US10080744, Example 4/1) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C26H28F6N4O5S2/c1-4-16(26(30,31)32)36-43(39,40)15-9-8-13(18(19(15)27)21(28)29)20-14(10-12-6-5-7-12)33-23(42-20)22-35-34-17(41-22)11-25(2,3)24(37)38/h8-9,12,16,21,36H,4-7,10-11H2,1-3H3,(H,37,38)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285797 (US10080744, Example 11/8) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC(C)(C)OC)-c2noc(CC(C)(C)OC=O)n2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C25H29Cl2F3N4O6S2/c1-7-16(25(28,29)30)34-42(36,37)15-9-8-13(18(26)19(15)27)20-14(10-23(2,3)38-6)31-22(41-20)21-32-17(40-33-21)11-24(4,5)39-12-35/h8-9,12,16,34H,7,10-11H2,1-6H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285801 (US10080744, Example 12) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CN2CCCC(F)(F)C2)-c2noc(CC(C)(C)C(O)=O)n2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C27H29F8N5O5S2/c1-4-16(27(33,34)35)39-47(43,44)15-7-6-13(18(19(15)28)21(29)30)20-14(11-40-9-5-8-26(31,32)12-40)36-23(46-20)22-37-17(45-38-22)10-25(2,3)24(41)42/h6-7,16,21,39H,4-5,8-12H2,1-3H3,(H,41,42)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285804 (US10080744, Example 12/3) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CN2CC(F)(F)C[C@@H]2C)-c2noc(CC(C)(C)C(O)=O)n2)c(C(F)F)c1F)C(F)(F)F |r| Show InChI InChI=1S/C27H29F8N5O5S2/c1-5-16(27(33,34)35)39-47(43,44)15-7-6-13(18(19(15)28)21(29)30)20-14(10-40-11-26(31,32)8-12(40)2)36-23(46-20)22-37-17(45-38-22)9-25(3,4)24(41)42/h6-7,12,16,21,39H,5,8-11H2,1-4H3,(H,41,42)/t12-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285756 (US10080744, Example 3/23) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccncc12)C(F)(F)F |r| Show InChI InChI=1S/C30H34F3N5O5S2/c1-4-23(30(31,32)33)38-45(41,42)22-11-10-19(18-12-13-34-16-20(18)22)25-21(14-17-8-6-5-7-9-17)35-27(44-25)26-37-36-24(43-26)15-29(2,3)28(39)40/h10-13,16-17,23,38H,4-9,14-15H2,1-3H3,(H,39,40)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285740 (US10080744, Example 3/8a) Show SMILES CC(N1CCOCC1(C)C)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)C(O)=O)o2)c2ccccc12 Show InChI InChI=1S/C33H40N4O4S/c1-20(37-15-16-40-19-33(37,4)5)22-13-14-25(24-12-7-6-11-23(22)24)28-26(17-21-9-8-10-21)34-30(42-28)29-36-35-27(41-29)18-32(2,3)31(38)39/h6-7,11-14,20-21H,8-10,15-19H2,1-5H3,(H,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285751 (US10080744, Example 3/18) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)OC=O)o2)c(OC(F)(F)F)c1)C(F)(F)F |r| Show InChI InChI=1S/C26H28F6N4O6S2/c1-4-19(25(27,28)29)36-44(38,39)15-8-9-16(18(11-15)42-26(30,31)32)21-17(10-14-6-5-7-14)33-23(43-21)22-35-34-20(41-22)12-24(2,3)40-13-37/h8-9,11,13-14,19,36H,4-7,10,12H2,1-3H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285752 (US10080744, Example 3/19) Show SMILES CC[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2nnc(CC(C)(C)OC=O)o2)c(Cl)c1)C(F)(F)F |r| Show InChI InChI=1S/C25H28ClF3N4O5S2/c1-4-19(25(27,28)29)33-40(35,36)15-8-9-16(17(26)11-15)21-18(10-14-6-5-7-14)30-23(39-21)22-32-31-20(38-22)12-24(2,3)37-13-34/h8-9,11,13-14,19,33H,4-7,10,12H2,1-3H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Homo sapiens (Human))	BDBM285813 (US10080744, Example 17) Show SMILES C[C@H](NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCC2)-c2cc(CC(C)(C)OC=O)ncn2)c(Cl)c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C26H27Cl2F3N4O4S2/c1-14(26(29,30)31)35-41(37,38)20-8-7-17(21(27)22(20)28)23-18(9-15-5-4-6-15)34-24(40-23)19-10-16(32-12-33-19)11-25(2,3)39-13-36/h7-8,10,12-15,35H,4-6,9,11H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...				US Patent US10080744 (2018) BindingDB Entry DOI: 10.7270/Q21J9CVM
					More data for this Ligand-Target Pair

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