Compile Data Set for Download or QSAR

Found 156 hits Enz. Inhib. hit(s) with all data for entry = 2003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350391 ((S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]...) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C19H15ClN8/c1-11(26-19-14(8-21)18(22)24-10-25-19)13-7-16-23-9-15(20)28(16)27-17(13)12-5-3-2-4-6-12/h2-7,9-11H,1H3,(H3,22,24,25,26)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350389 (4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyri...) Show SMILES CC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1 Show InChI InChI=1S/C19H15ClN8/c1-11(26-19-14(8-21)18(22)24-10-25-19)13-7-16-23-9-15(20)28(16)27-17(13)12-5-3-2-4-6-12/h2-7,9-11H,1H3,(H3,22,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350454 ((S)-4-amino-6-(0-(3-fluoro-6-phenylimidazo[1,2-b]p...) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(F)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C19H15FN8/c1-11(26-19-14(8-21)18(22)24-10-25-19)13-7-16-23-9-15(20)28(16)27-17(13)12-5-3-2-4-6-12/h2-7,9-11H,1H3,(H3,22,24,25,26)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350447 ((S)-4-amino-6-((1-(3-chloro-6-(2-hydroxyphenyl)imi...) Show SMILES COc1ccccc1-c1nn2c(Cl)cnc2cc1[C@H](C)Nc1ncnc(N)c1C#N |r| Show InChI InChI=1S/C20H17ClN8O/c1-11(27-20-14(8-22)19(23)25-10-26-20)13-7-17-24-9-16(21)29(17)28-18(13)12-5-3-4-6-15(12)30-2/h3-7,9-11H,1-2H3,(H3,23,25,26,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350438 (US10208066, Compound 60 | US10611777, Compound 60) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccsc1 |r| Show InChI InChI=1S/C17H13ClN8S/c1-9(24-17-12(5-19)16(20)22-8-23-17)11-4-14-21-6-13(18)26(14)25-15(11)10-2-3-27-7-10/h2-4,6-9H,1H3,(H3,20,22,23,24)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM350430 (US10208066, Compound 49 | US10611777, Compound 49) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H15ClN8O/c1-10(26-19-14(7-21)18(22)24-9-25-19)13-6-16-23-8-15(20)28(16)27-17(13)11-2-4-12(29)5-3-11/h2-6,8-10,29H,1H3,(H3,22,24,25,26)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350430 (US10208066, Compound 49 | US10611777, Compound 49) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H15ClN8O/c1-10(26-19-14(7-21)18(22)24-9-25-19)13-6-16-23-8-15(20)28(16)27-17(13)11-2-4-12(29)5-3-11/h2-6,8-10,29H,1H3,(H3,22,24,25,26)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350398 (US10208066, Compound 15 | US10611777, Compound 15) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(F)c1 |r| Show InChI InChI=1S/C19H14ClFN8/c1-10(27-19-14(7-22)18(23)25-9-26-19)13-6-16-24-8-15(20)29(16)28-17(13)11-3-2-4-12(21)5-11/h2-6,8-10H,1H3,(H3,23,25,26,27)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350392 ((S)-4-amino-6-((1-(6-phenylimidazo[1,2-b]pyridazin...) Show SMILES CC[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C20H17ClN8/c1-2-15(27-20-14(9-22)19(23)25-11-26-20)13-8-17-24-10-16(21)29(17)28-18(13)12-6-4-3-5-7-12/h3-8,10-11,15H,2H2,1H3,(H3,23,25,26,27)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350389 (4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyri...) Show SMILES CC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1 Show InChI InChI=1S/C19H15ClN8/c1-11(26-19-14(8-21)18(22)24-10-25-19)13-7-16-23-9-15(20)28(16)27-17(13)12-5-3-2-4-6-12/h2-7,9-11H,1H3,(H3,22,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350396 (US10208066, Compound 12 | US10611777, Compound 12) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1F |r| Show InChI InChI=1S/C19H14ClFN8/c1-10(27-19-13(7-22)18(23)25-9-26-19)12-6-16-24-8-15(20)29(16)28-17(12)11-4-2-3-5-14(11)21/h2-6,8-10H,1H3,(H3,23,25,26,27)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350455 ((chiral)-amino-6-((1-(3-chloro-6-(3-(2-hydroxyprop...) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(c1)C(C)(C)O |r| Show InChI InChI=1S/C22H21ClN8O/c1-12(29-21-16(9-24)20(25)27-11-28-21)15-8-18-26-10-17(23)31(18)30-19(15)13-5-4-6-14(7-13)22(2,3)32/h4-8,10-12,32H,1-3H3,(H3,25,27,28,29)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350457 ((S)-N4-(1-(3-chloro-6-phenylimidazo[1,2-b]pyridazi...) Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C21H18ClN9O/c1-11(27-20-17(19(23)25-10-26-20)21-29-28-12(2)32-21)14-8-16-24-9-15(22)31(16)30-18(14)13-6-4-3-5-7-13/h3-11H,1-2H3,(H3,23,25,26,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350407 (US10208066, Compound 24 | US10611777, Compound 24) Show SMILES CCC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(F)c1 Show InChI InChI=1S/C20H16ClFN8/c1-2-15(28-20-14(8-23)19(24)26-10-27-20)13-7-17-25-9-16(21)30(17)29-18(13)11-4-3-5-12(22)6-11/h3-7,9-10,15H,2H2,1H3,(H3,24,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350440 (US10208066, Compound 62 | US10611777, Compound 62) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(C)c1 |r| Show InChI InChI=1S/C20H17ClN8/c1-11-4-3-5-13(6-11)18-14(7-17-24-9-16(21)29(17)28-18)12(2)27-20-15(8-22)19(23)25-10-26-20/h3-7,9-10,12H,1-2H3,(H3,23,25,26,27)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350394 (US10208066, Compound 9) Show SMILES C[C@H](Nc1ncnc2[nH]cc(C#N)c12)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350446 (US10208066, Compound 68 | US10611777, Compound 68) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1S(C)(=O)=O |r| Show InChI InChI=1S/C20H17ClN8O2S/c1-11(27-20-14(8-22)19(23)25-10-26-20)13-7-17-24-9-16(21)29(17)28-18(13)12-5-3-4-6-15(12)32(2,30)31/h3-7,9-11H,1-2H3,(H3,23,25,26,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350434 (US10208066, Compound 54 | US10611777, Compound 54) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(O)c1 |r| Show InChI InChI=1S/C19H15ClN8O/c1-10(26-19-14(7-21)18(22)24-9-25-19)13-6-16-23-8-15(20)28(16)27-17(13)11-3-2-4-12(29)5-11/h2-6,8-10,29H,1H3,(H3,22,24,25,26)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350443 (US10208066, Compound 65 | US10611777, Compound 65) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(c1)C#N |r| Show InChI InChI=1S/C20H14ClN9/c1-11(28-20-15(8-23)19(24)26-10-27-20)14-6-17-25-9-16(21)30(17)29-18(14)13-4-2-3-12(5-13)7-22/h2-6,9-11H,1H3,(H3,24,26,27,28)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350421 (US10208066, Compound 40 | US10611777, Compound 40) Show SMILES C[C@H](Nc1ncnc(N)c1Cl)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C18H15Cl2N7/c1-10(25-18-15(20)17(21)23-9-24-18)12-7-14-22-8-13(19)27(14)26-16(12)11-5-3-2-4-6-11/h2-10H,1H3,(H3,21,23,24,25)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350405 (US10208066, Compound 22 | US10611777, Compound 22) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(C)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C20H18N8/c1-12-10-23-17-8-15(18(27-28(12)17)14-6-4-3-5-7-14)13(2)26-20-16(9-21)19(22)24-11-25-20/h3-8,10-11,13H,1-2H3,(H3,22,24,25,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350402 (US10208066, Compound 19 | US10611777, Compound 19) Show SMILES CCC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1F Show InChI InChI=1S/C20H16ClFN8/c1-2-15(28-20-13(8-23)19(24)26-10-27-20)12-7-17-25-9-16(21)30(17)29-18(12)11-5-3-4-6-14(11)22/h3-7,9-10,15H,2H2,1H3,(H3,24,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350453 (US10208066, Compound 77 | US10611777, Compound 77) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccnc1 |r| Show InChI InChI=1S/C18H14ClN9/c1-10(26-18-13(6-20)17(21)24-9-25-18)12-5-15-23-8-14(19)28(15)27-16(12)11-3-2-4-22-7-11/h2-5,7-10H,1H3,(H3,21,24,25,26)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350399 (US10208066, Compound 16 | US10611777, Compound 16) Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1cc2ncc(Cl)n2nc1-c1cccc(F)c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350417 (US10208066, Compound 36 | US10611777, Compound 36) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(F)c1F |r| Show InChI InChI=1S/C19H13ClF2N8/c1-9(28-19-12(6-23)18(24)26-8-27-19)11-5-15-25-7-14(20)30(15)29-17(11)10-3-2-4-13(21)16(10)22/h2-5,7-9H,1H3,(H3,24,26,27,28)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350411 (US10208066, Compound 29 | US10611777, Compound 29) Show SMILES CCC(Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccn1 Show InChI InChI=1S/C19H16ClN9/c1-2-13(27-19-12(8-21)18(22)25-10-26-19)11-7-16-24-9-15(20)29(16)28-17(11)14-5-3-4-6-23-14/h3-7,9-10,13H,2H2,1H3,(H3,22,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350397 (US10208066, Compound 13 | US10611777, Compound 13) Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1cc2ncc(Cl)n2nc1-c1ccccc1F |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350422 (US10208066, Compound 41 | US10611777, Compound 41) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C19H14Cl2N8/c1-10(27-19-14(7-22)18(23)25-9-26-19)13-6-16-24-8-15(21)29(16)28-17(13)11-3-2-4-12(20)5-11/h2-6,8-10H,1H3,(H3,23,25,26,27)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350426 (US10208066, Compound 45 | US10611777, Compound 45) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C20H14ClF3N8/c1-10(30-19-13(7-25)18(26)28-9-29-19)12-6-16-27-8-15(21)32(16)31-17(12)11-4-2-3-5-14(11)20(22,23)24/h2-6,8-10H,1H3,(H3,26,28,29,30)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350395 (US10208066, Compound 11) Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350412 ((S)-4-amino-6-((1-(3-chloro-6-(3,5-difluorophenyl)...) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C19H13ClF2N8/c1-9(28-19-14(6-23)18(24)26-8-27-19)13-5-16-25-7-15(20)30(16)29-17(13)10-2-11(21)4-12(22)3-10/h2-5,7-9H,1H3,(H3,24,26,27,28)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350408 (US10208066, Compound 25 | US10208066, Compound 26) Show SMILES CCC(Nc1ncnc2[nH]cnc12)c1cc2ncc(Cl)n2nc1-c1ccccc1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350427 (US10208066, Compound 46 | US10611777, Compound 46) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C20H17ClN8O2S/c1-11(27-20-15(8-22)19(23)25-10-26-20)14-7-17-24-9-16(21)29(17)28-18(14)12-4-3-5-13(6-12)32(2,30)31/h3-7,9-11H,1-2H3,(H3,23,25,26,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350413 ((S)-4-amino-6-((1-(3-chloro-6-(o-tolyl)imidazo[1,2...) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccc1C Show InChI InChI=1S/C20H17ClN8/c1-11-5-3-4-6-13(11)18-14(7-17-24-9-16(21)29(17)28-18)12(2)27-20-15(8-22)19(23)25-10-26-20/h3-7,9-10,12H,1-2H3,(H3,23,25,26,27)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350416 (US10208066, Compound 35 | US10611777, Compound 35) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cc(F)ccc1F |r| Show InChI InChI=1S/C19H13ClF2N8/c1-9(28-19-13(6-23)18(24)26-8-27-19)11-5-16-25-7-15(20)30(16)29-17(11)12-4-10(21)2-3-14(12)22/h2-5,7-9H,1H3,(H3,24,26,27,28)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350450 (US10208066, Compound 72 | US10611777, Compound 72) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cnn(C)c1 |r| Show InChI InChI=1S/C17H15ClN10/c1-9(25-17-12(4-19)16(20)22-8-23-17)11-3-14-21-6-13(18)28(14)26-15(11)10-5-24-27(2)7-10/h3,5-9H,1-2H3,(H3,20,22,23,25)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350401 (US10208066, Compound 18 | US10611777, Compound 18) Show SMILES CCC(Nc1ncnc2[nH]cnc12)c1cc2ncc(Cl)n2nc1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350437 (US10208066, Compound 59 | US10611777, Compound 59) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2nc(C)c(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C20H17ClN8/c1-11(27-20-15(9-22)19(23)24-10-25-20)14-8-16-26-12(2)18(21)29(16)28-17(14)13-6-4-3-5-7-13/h3-8,10-11H,1-2H3,(H3,23,24,25,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350445 (US10208066, Compound 67 | US10611777, Compound 67) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cc(C)cc(F)c1 |r| Show InChI InChI=1S/C20H16ClFN8/c1-10-3-12(5-13(22)4-10)18-14(6-17-25-8-16(21)30(17)29-18)11(2)28-20-15(7-23)19(24)26-9-27-20/h3-6,8-9,11H,1-2H3,(H3,24,26,27,28)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350406 (US10208066, Compound 23) Show SMILES C[C@H](Nc1ncnc2[nH]cnc12)c1cc2ncc(C)n2nc1-c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350441 (US10208066, Compound 63 | US10611777, Compound 63) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C19H13ClF2N8/c1-9(28-19-12(6-23)18(24)26-8-27-19)11-5-16-25-7-15(20)30(16)29-17(11)10-2-3-13(21)14(22)4-10/h2-5,7-9H,1H3,(H3,24,26,27,28)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350404 ((S)-N4-(1-(3-chloro-6-phenylimidazo[1,2-b]pyridazi...) Show SMILES C[C@H](Nc1ncnc(N)c1-c1nn[nH]n1)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350439 (US10208066, Compound 61 | US10611777, Compound 61) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc2cccnc2c1 |r| Show InChI InChI=1S/C22H16ClN9/c1-12(30-22-16(9-24)21(25)28-11-29-22)15-8-19-27-10-18(23)32(19)31-20(15)14-5-4-13-3-2-6-26-17(13)7-14/h2-8,10-12H,1H3,(H3,25,28,29,30)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350452 (US10208066, Compound 74 | US10611777, Compound 74) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccc2scnc2c1 |r| Show InChI InChI=1S/C20H14ClN9S/c1-10(28-20-13(6-22)19(23)25-8-26-20)12-5-17-24-7-16(21)30(17)29-18(12)11-2-3-15-14(4-11)27-9-31-15/h2-5,7-10H,1H3,(H3,23,25,26,28)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350429 (US10208066, Compound 48 | US10611777, Compound 48) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C20H14ClF3N8/c1-10(30-19-14(7-25)18(26)28-9-29-19)13-6-16-27-8-15(21)32(16)31-17(13)11-3-2-4-12(5-11)20(22,23)24/h2-6,8-10H,1H3,(H3,26,28,29,30)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM350434 (US10208066, Compound 54 | US10611777, Compound 54) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cccc(O)c1 |r| Show InChI InChI=1S/C19H15ClN8O/c1-10(26-19-14(7-21)18(22)24-9-25-19)13-6-16-23-8-15(20)28(16)27-17(13)11-3-2-4-12(29)5-11/h2-6,8-10,29H,1H3,(H3,22,24,25,26)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350444 (US10208066, Compound 66 | US10611777, Compound 66) Show SMILES C[C@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1cc(F)cc(Cl)c1 |r| Show InChI InChI=1S/C19H13Cl2FN8/c1-9(28-19-14(6-23)18(24)26-8-27-19)13-5-16-25-7-15(21)30(16)29-17(13)10-2-11(20)4-12(22)3-10/h2-5,7-9H,1H3,(H3,24,26,27,28)/t9-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350393 ((S)-4-amino-6-((1-(3-chloro-6-(pyridin-2-yl)imidaz...) Show SMILES C[C@@H](Nc1ncnc(N)c1C#N)c1cc2ncc(Cl)n2nc1-c1ccccn1 |r| Show InChI InChI=1S/C18H14ClN9/c1-10(26-18-12(7-20)17(21)24-9-25-18)11-6-15-23-8-14(19)28(15)27-16(11)13-4-2-3-5-22-13/h2-6,8-10H,1H3,(H3,21,24,25,26)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350432 ((S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]...) Show SMILES C[C@H](Nc1ncnc(N)c1C(O)=O)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C19H16ClN7O2/c1-10(25-18-15(19(28)29)17(21)23-9-24-18)12-7-14-22-8-13(20)27(14)26-16(12)11-5-3-2-4-6-11/h2-10H,1H3,(H,28,29)(H3,21,23,24,25)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM350458 ((S)-N4-(1-(3-chloro-6-phenylimidazo[1,2-b]pyridazi...) Show SMILES C[C@H](Nc1ncnc(N)c1-c1nc(C)no1)c1cc2ncc(Cl)n2nc1-c1ccccc1 |r| Show InChI InChI=1S/C21H18ClN9O/c1-11(27-20-17(19(23)25-10-26-20)21-28-12(2)30-32-21)14-8-16-24-9-15(22)31(16)29-18(14)13-6-4-3-5-7-13/h3-11H,1-2H3,(H3,23,25,26,27)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
HUTCHISON MEDIPHARMA LIMITED US Patent					Assay Description Briefly, the Transcreener KINASE Assay was designed as a simple two-part, endpoint assay as follows:1) Preparation of 25 uL kinase reaction: the 25 u...				US Patent US10208066 (2019) BindingDB Entry DOI: 10.7270/Q2319Z0W
					More data for this Ligand-Target Pair

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