Compile Data Set for Download or QSAR

Found 170 hits Enz. Inhib. hit(s) with all data for entry = 2570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371829 (2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)Nc1ccccc1 Show InChI InChI=1S/C29H28N6O3/c36-26(31-23-7-3-1-4-8-23)19-34-20-35(24-9-5-2-6-10-24)29(28(34)38)13-15-33(16-14-29)27(37)21-11-12-25-22(17-21)18-30-32-25/h1-12,17-18H,13-16,19-20H2,(H,30,32)(H,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371835 ((rac, trans)-2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)N[C@H]1C[C@@H]1c1ccccc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372088 (N-Cyclopropyl-2-[4-oxo-1-phenyl-8-(1H-pyrazolo[3,4...) Show SMILES FC(F)(F)CN(C1CC1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C27H28F3N7O3/c28-27(29,30)16-36(20-6-7-20)22(38)15-35-17-37(21-4-2-1-3-5-21)26(25(35)40)8-10-34(11-9-26)24(39)19-12-18-14-32-33-23(18)31-13-19/h1-5,12-14,20H,6-11,15-17H2,(H,31,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371821 (2-[1-(3-Fluoro-phenyl)-4-oxo-8-(1H-pyrazolo[3,4-b]...) Show SMILES Fc1cccc(c1)N1CN(CC(=O)NCC(F)(F)F)C(=O)C11CCN(CC1)C(=O)c1cnc2[nH]ncc2c1 Show InChI InChI=1S/C24H23F4N7O3/c25-17-2-1-3-18(9-17)35-14-34(12-19(36)30-13-24(26,27)28)22(38)23(35)4-6-33(7-5-23)21(37)16-8-15-11-31-32-20(15)29-10-16/h1-3,8-11H,4-7,12-14H2,(H,30,36)(H,29,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372102 (2-(1-(3-Chlorophenyl)-4-oxo-8-(1H-pyrazolo[3,4-b]p...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2cccc(Cl)c2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C24H23ClF3N7O3/c25-17-2-1-3-18(9-17)35-14-34(12-19(36)30-13-24(26,27)28)22(38)23(35)4-6-33(7-5-23)21(37)16-8-15-11-31-32-20(15)29-10-16/h1-3,8-11H,4-7,12-14H2,(H,30,36)(H,29,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371932 (3-[(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-8-(...) Show SMILES O=C(N1CCC2(CC1)N(CN(Cc1nc(no1)C1CC1)C2=O)c1ccccc1)c1ccc2[nH]ncc2c1 Show InChI InChI=1S/C27H27N7O3/c35-25(19-8-9-22-20(14-19)15-28-30-22)32-12-10-27(11-13-32)26(36)33(17-34(27)21-4-2-1-3-5-21)16-23-29-24(31-37-23)18-6-7-18/h1-5,8-9,14-15,18H,6-7,10-13,16-17H2,(H,28,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	US Patent	n/a	n/a	13.8	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371847 (2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)Nc1ccccn1 Show InChI InChI=1S/C28H27N7O3/c36-25(31-24-8-4-5-13-29-24)18-34-19-35(22-6-2-1-3-7-22)28(27(34)38)11-14-33(15-12-28)26(37)20-9-10-23-21(16-20)17-30-32-23/h1-10,13,16-17H,11-12,14-15,18-19H2,(H,30,32)(H,29,31,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371830 (2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C25H25F3N6O3/c26-25(27,28)15-29-21(35)14-33-16-34(19-4-2-1-3-5-19)24(23(33)37)8-10-32(11-9-24)22(36)17-6-7-20-18(12-17)13-30-31-20/h1-7,12-13H,8-11,14-16H2,(H,29,35)(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372136 (2-[8-(1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES FC(F)(F)C1(CC1)NC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C27H27F3N6O3/c28-27(29,30)26(8-9-26)32-22(37)16-35-17-36(20-4-2-1-3-5-20)25(24(35)39)10-12-34(13-11-25)23(38)18-6-7-21-19(14-18)15-31-33-21/h1-7,14-15H,8-13,16-17H2,(H,31,33)(H,32,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372052 (2-[4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES CC(C)N(CC(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C27H30F3N7O3/c1-18(2)36(16-27(28,29)30)22(38)15-35-17-37(21-6-4-3-5-7-21)26(25(35)40)8-10-34(11-9-26)24(39)20-12-19-14-32-33-23(19)31-13-20/h3-7,12-14,18H,8-11,15-17H2,1-2H3,(H,31,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371865 (2-[4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C24H24F3N7O3/c25-24(26,27)14-29-19(35)13-33-15-34(18-4-2-1-3-5-18)23(22(33)37)6-8-32(9-7-23)21(36)17-10-16-12-30-31-20(16)28-11-17/h1-5,10-12H,6-9,13-15H2,(H,29,35)(H,28,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372117 ((R)- or (S)-3-(2-Oxo-2-(2-(trifluoromethyl)morphol...) Show SMILES FC(F)(F)[C@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3n2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372092 ((S)-3-(2-Oxo-2-(2-(trifluoromethyl)pyrrolidin-1-yl...) Show SMILES FC(F)(F)C1CCCN1C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372139 (2-(8-(7-Methyl-1H-indazole-5-carbonyl)-4-oxo-1-phe...) Show SMILES Cc1cc(cc2cn[nH]c12)C(=O)N1CCC2(CC1)N(CN(CC(=O)NCC(F)(F)F)C2=O)c1ccccc1 Show InChI InChI=1S/C26H27F3N6O3/c1-17-11-18(12-19-13-31-32-22(17)19)23(37)33-9-7-25(8-10-33)24(38)34(14-21(36)30-15-26(27,28)29)16-35(25)20-5-3-2-4-6-20/h2-6,11-13H,7-10,14-16H2,1H3,(H,30,36)(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372125 ((S)- or (R)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-...) Show SMILES FC(F)(F)[C@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.1	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372078 (2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES CN(CC(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C26H27F3N6O3/c1-32(16-26(27,28)29)22(36)15-34-17-35(20-5-3-2-4-6-20)25(24(34)38)9-11-33(12-10-25)23(37)18-7-8-21-19(13-18)14-30-31-21/h2-8,13-14H,9-12,15-17H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372045 (3-[2-(3,3-Difluoropyrrolidin-1-yl)-2-oxoethyl]-1-p...) Show SMILES FC1(F)CCN(C1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C26H27F2N7O3/c27-26(28)8-11-33(16-26)21(36)15-34-17-35(20-4-2-1-3-5-20)25(24(34)38)6-9-32(10-7-25)23(37)19-12-18-14-30-31-22(18)29-13-19/h1-5,12-14H,6-11,15-17H2,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372046 ((RS)-3-[2-(2,2-Difluoro-5-azaspiro[2.4]heptan-5-yl...) Show SMILES FC1(F)CC11CCN(C1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372110 (8-(1H-Indazole-5-carbonyl)-3-[2-[4-methyl-3-(trifl...) Show SMILES CN1CCN(CC1C(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372068 (2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[4,3-b]pyridine-5-...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3n2)C1=O Show InChI InChI=1S/C24H24F3N7O3/c25-24(26,27)14-28-20(35)13-33-15-34(16-4-2-1-3-5-16)23(22(33)37)8-10-32(11-9-23)21(36)18-7-6-17-19(30-18)12-29-31-17/h1-7,12H,8-11,13-15H2,(H,28,35)(H,29,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371875 (2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O)Nc1ccccc1 Show InChI InChI=1S/C28H27N7O3/c36-24(31-22-7-3-1-4-8-22)18-34-19-35(23-9-5-2-6-10-23)28(27(34)38)11-13-33(14-12-28)26(37)21-15-20-17-30-32-25(20)29-16-21/h1-10,15-17H,11-14,18-19H2,(H,31,36)(H,29,30,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372081 (2-(8-(3-Amino-1H-indazole-5-carbonyl)-4-oxo-1-phen...) Show SMILES Nc1n[nH]c2ccc(cc12)C(=O)N1CCC2(CC1)N(CN(CC(=O)NCC(F)(F)F)C2=O)c1ccccc1 Show InChI InChI=1S/C25H26F3N7O3/c26-25(27,28)14-30-20(36)13-34-15-35(17-4-2-1-3-5-17)24(23(34)38)8-10-33(11-9-24)22(37)16-6-7-19-18(12-16)21(29)32-31-19/h1-7,12H,8-11,13-15H2,(H,30,36)(H3,29,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372090 ((−)-2-[8-(1H-Indazole-5-carbonyl)-4-oxo-1-ph...) Show SMILES C[C@@H](N1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)C(=O)NCC(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372114 (N-(2-(Morpholinomethyl)phenyl)-2-(4-oxo-1-phenyl-8...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O)Nc1ccccc1CN1CCOCC1 Show InChI InChI=1S/C33H36N8O4/c42-29(36-28-9-5-4-6-24(28)21-38-14-16-45-17-15-38)22-40-23-41(27-7-2-1-3-8-27)33(32(40)44)10-12-39(13-11-33)31(43)26-18-25-20-35-37-30(25)34-19-26/h1-9,18-20H,10-17,21-23H2,(H,36,42)(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.1	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372120 ((R)- or (S)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-...) Show SMILES FC(F)(F)[C@@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371983 ((RS)-3-[2-Oxo-2-[3-(trifluoromethyl)pyrrolidin-1-y...) Show SMILES FC(F)(F)C1CCN(C1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.8	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371993 (3-[2-(3,3-Dimethylpyrrolidin-1-yl)-2-oxoethyl]-8-(...) Show SMILES CC1(C)CCN(C1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C29H34N6O3/c1-28(2)10-13-33(19-28)25(36)18-34-20-35(23-6-4-3-5-7-23)29(27(34)38)11-14-32(15-12-29)26(37)21-8-9-24-22(16-21)17-30-31-24/h3-9,16-17H,10-15,18-20H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372080 (2-(8-(3-Methyl-1H-indazole-5-carbonyl)-4-oxo-1-phe...) Show SMILES Cc1n[nH]c2ccc(cc12)C(=O)N1CCC2(CC1)N(CN(CC(=O)NCC(F)(F)F)C2=O)c1ccccc1 Show InChI InChI=1S/C26H27F3N6O3/c1-17-20-13-18(7-8-21(20)32-31-17)23(37)33-11-9-25(10-12-33)24(38)34(14-22(36)30-15-26(27,28)29)16-35(25)19-5-3-2-4-6-19/h2-8,13H,9-12,14-16H2,1H3,(H,30,36)(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371921 (N-(Adamantan-1-yl)-2-(4-oxo-1-phenyl-8-(1H-pyrazol...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O)NC12CC3CC(CC(C3)C1)C2 |TLB:35:36:33.34.39:40,39:34:41:38.40.37,39:38:33.34.35:41,THB:35:34:40:36.41.37| Show InChI InChI=1S/C32H37N7O3/c40-27(35-31-14-21-10-22(15-31)12-23(11-21)16-31)19-38-20-39(26-4-2-1-3-5-26)32(30(38)42)6-8-37(9-7-32)29(41)25-13-24-18-34-36-28(24)33-17-25/h1-5,13,17-18,21-23H,6-12,14-16,19-20H2,(H,35,40)(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.1	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372044 ((RS)-3-[2-(3-Fluoro-3-methylpyrrolidin-1-yl)-2-oxo...) Show SMILES CC1(F)CCN(C1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372122 ((S)- or (R)-3-(2-Oxo-2-(2-(trifluoromethyl)morphol...) Show SMILES FC(F)(F)[C@@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3n2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372129 (8-(1H-Indazole-5-carbonyl)-3-[2-[(3S or 3R)-4-meth...) Show SMILES CN1CCN(C[C@H]1C(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.5	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371909 (N-Methyl-2-(4-oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]py...) Show SMILES CN(CC(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C25H26F3N7O3/c1-32(15-25(26,27)28)20(36)14-34-16-35(19-5-3-2-4-6-19)24(23(34)38)7-9-33(10-8-24)22(37)18-11-17-13-30-31-21(17)29-12-18/h2-6,11-13H,7-10,14-16H2,1H3,(H,29,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.6	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372137 (N-(2-cyanopropan-2-yl)-2-[8-(1H-indazole-5-carbony...) Show SMILES CC(C)(NC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)C#N Show InChI InChI=1S/C27H29N7O3/c1-26(2,17-28)30-23(35)16-33-18-34(21-6-4-3-5-7-21)27(25(33)37)10-12-32(13-11-27)24(36)19-8-9-22-20(14-19)15-29-31-22/h3-9,14-15H,10-13,16,18H2,1-2H3,(H,29,31)(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.2	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372085 (N-(6-Cyanopyridin-2-yl)-2-[4-oxo-1-phenyl-8-(1H-py...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O)Nc1cccc(n1)C#N Show InChI InChI=1S/C28H25N9O3/c29-14-21-5-4-8-23(32-21)33-24(38)17-36-18-37(22-6-2-1-3-7-22)28(27(36)40)9-11-35(12-10-28)26(39)20-13-19-16-31-34-25(19)30-15-20/h1-8,13,15-16H,9-12,17-18H2,(H,30,31,34)(H,32,33,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372119 ((R)- or (S)-8-(1H-Indazole-5-carbonyl)-3-(2-oxo-2-...) Show SMILES FC(F)(F)[C@H]1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372101 (3-(2-Oxo-2-(2-(trifluoromethyl)morpholino)ethyl)-1...) Show SMILES FC(F)(F)C1CN(CCO1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372082 (2-[8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES CC(N1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)C(=O)NCC(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372133 (N-(2-hydroxyethyl)-2-[8-(1H-indazole-5-carbonyl)-4...) Show SMILES OCCN(CC(F)(F)F)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O Show InChI InChI=1S/C27H29F3N6O4/c28-27(29,30)17-34(12-13-37)23(38)16-35-18-36(21-4-2-1-3-5-21)26(25(35)40)8-10-33(11-9-26)24(39)19-6-7-22-20(14-19)15-31-32-22/h1-7,14-15,37H,8-13,16-18H2,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372146 (2-[1-(3-Chloro-5-fluorophenyl)-4-oxo-8-(1H-pyrazol...) Show SMILES Fc1cc(Cl)cc(c1)N1CN(CC(=O)NCC(F)(F)F)C(=O)C11CCN(CC1)C(=O)c1cnc2[nH]ncc2c1 Show InChI InChI=1S/C24H22ClF4N7O3/c25-16-6-17(26)8-18(7-16)36-13-35(11-19(37)31-12-24(27,28)29)22(39)23(36)1-3-34(4-2-23)21(38)15-5-14-10-32-33-20(14)30-9-15/h5-10H,1-4,11-13H2,(H,31,37)(H,30,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371833 (2-(8-(1H-Indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)NCCN1CCOCC1 Show InChI InChI=1S/C29H35N7O4/c37-26(30-10-13-33-14-16-40-17-15-33)20-35-21-36(24-4-2-1-3-5-24)29(28(35)39)8-11-34(12-9-29)27(38)22-6-7-25-23(18-22)19-31-32-25/h1-7,18-19H,8-17,20-21H2,(H,30,37)(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372130 ((R) or (S)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-(...) Show SMILES FC(F)(F)[C@H]1CN(CCN1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41.9	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371836 (8-(1H-Indazole-5-carbonyl)-3-(2-morpholino-2-oxoet...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O)N1CCOCC1 Show InChI InChI=1S/C27H30N6O4/c34-24(30-12-14-37-15-13-30)18-32-19-33(22-4-2-1-3-5-22)27(26(32)36)8-10-31(11-9-27)25(35)20-6-7-23-21(16-20)17-28-29-23/h1-7,16-17H,8-15,18-19H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372067 (2-(3-((2-(8-(1H-indazole-5-carbonyl)-4-oxo-1-pheny...) Show SMILES CNC(=O)Cc1cccc(CNC(=O)CN2CN(c3ccccc3)C3(CCN(CC3)C(=O)c3ccc4[nH]ncc4c3)C2=O)c1 Show InChI InChI=1S/C33H35N7O4/c1-34-29(41)17-23-6-5-7-24(16-23)19-35-30(42)21-39-22-40(27-8-3-2-4-9-27)33(32(39)44)12-14-38(15-13-33)31(43)25-10-11-28-26(18-25)20-36-37-28/h2-11,16,18,20H,12-15,17,19,21-22H2,1H3,(H,34,41)(H,35,42)(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.1	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371856 (2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-c]pyridine-5-...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cc3cn[nH]c3cn2)C1=O Show InChI InChI=1S/C24H24F3N7O3/c25-24(26,27)14-29-20(35)13-33-15-34(17-4-2-1-3-5-17)23(22(33)37)6-8-32(9-7-23)21(36)18-10-16-11-30-31-19(16)12-28-18/h1-5,10-12H,6-9,13-15H2,(H,29,35)(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372100 (N-(2-(2-((4-methylpiperazin-1-yl)methyl)phenyl)cyc...) Show SMILES CN1CCN(Cc2ccccc2C2CC2NC(=O)CN2CN(c3ccccc3)C3(CCN(CC3)C(=O)c3cnc4[nH]ncc4c3)C2=O)CC1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45.6	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM372131 ((S)- or (R)-8-(1H-indazole-5-carbonyl)-3-(2-oxo-2-...) Show SMILES FC(F)(F)[C@@H]1CN(CCN1)C(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)C1=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371880 (2-(4-Oxo-1-phenyl-8-(1H-pyrazolo[3,4-b]pyridine-5-...) Show SMILES O=C(CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cnc3[nH]ncc3c2)C1=O)Nc1ccccn1 Show InChI InChI=1S/C27H26N8O3/c36-23(31-22-8-4-5-11-28-22)17-34-18-35(21-6-2-1-3-7-21)27(26(34)38)9-12-33(13-10-27)25(37)20-14-19-16-30-32-24(19)29-15-20/h1-8,11,14-16H,9-10,12-13,17-18H2,(H,28,31,36)(H,29,30,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49.4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371857 (2-(8-(Imidazo[1,5-a]pyridine-6-carbonyl)-4-oxo-1-p...) Show SMILES FC(F)(F)CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)c2cn3cncc3cn2)C1=O Show InChI InChI=1S/C24H24F3N7O3/c25-24(26,27)14-30-20(35)13-33-16-34(17-4-2-1-3-5-17)23(22(33)37)6-8-31(9-7-23)21(36)19-12-32-15-28-10-18(32)11-29-19/h1-5,10-12,15H,6-9,13-14,16H2,(H,30,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54.6	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM371966 ((RS)-2-[8-(1H-Indazole-5-carbonyl)-2-methyl-4-oxo-...) Show SMILES CC1N(CC(=O)NCC(F)(F)F)C(=O)C2(CCN(CC2)C(=O)c2ccc3[nH]ncc3c2)N1c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	54.7	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description This assay is based on the intracellular domain of the DDR1 protein which contains the kinase active site. The recombinant protein additionally carri...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2D220ZB
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 170 total )  |  Next  |  Last  >>

Jump to: