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PubMed code 12801227

Compile data set for download or QSAR
Found 87 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129663
PNG
(3-But-3-enoylamino-pyridine-2-carboxylic acid thia...)
Show SMILES C=CCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C13H12N4O2S/c1-2-4-10(18)16-9-5-3-6-14-11(9)12(19)17-13-15-7-8-20-13/h2-3,5-8H,1,4H2,(H,16,18)(H,15,17,19)
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n/an/a 130n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129648
PNG
(3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C15H16N4O2S/c1-10(2)5-6-12(20)18-11-4-3-7-16-13(11)14(21)19-15-17-8-9-22-15/h3-5,7-9H,6H2,1-2H3,(H,18,20)(H,17,19,21)
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n/an/a 140n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129660
PNG
(3-(3-Methyl-but-3-enoylamino)-pyridine-2-carboxyli...)
Show SMILES CC(=C)CC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-9(2)8-11(19)17-10-4-3-5-15-12(10)13(20)18-14-16-6-7-21-14/h3-7H,1,8H2,2H3,(H,17,19)(H,16,18,20)
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n/an/a 150n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM17847
PNG
(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)
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n/an/a 180n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129642
PNG
(CHEMBL86427 | Phenyl-acetic acid 2-(thiazol-2-ylca...)
Show SMILES O=C(Cc1ccccc1)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H13N3O3S/c21-14(11-12-5-2-1-3-6-12)23-13-7-4-8-18-15(13)16(22)20-17-19-9-10-24-17/h1-10H,11H2,(H,19,20,22)
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n/an/a 200n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129640
PNG
(3-(3-Methyl-but-2-enoylamino)-pyridine-2-carboxyli...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-9(2)8-11(19)17-10-4-3-5-15-12(10)13(20)18-14-16-6-7-21-14/h3-8H,1-2H3,(H,17,19)(H,16,18,20)
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n/an/a 220n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129648
PNG
(3-(4-Methyl-pent-3-enoylamino)-pyridine-2-carboxyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C15H16N4O2S/c1-10(2)5-6-12(20)18-11-4-3-7-16-13(11)14(21)19-15-17-8-9-22-15/h3-5,7-9H,6H2,1-2H3,(H,18,20)(H,17,19,21)
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n/an/a 240n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129672
PNG
(3-Propionylamino-pyridine-2-carboxylic acid thiazo...)
Show SMILES CCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C12H12N4O2S/c1-2-9(17)15-8-4-3-5-13-10(8)11(18)16-12-14-6-7-19-12/h3-7H,2H2,1H3,(H,15,17)(H,14,16,18)
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n/an/a 260n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129674
PNG
(3-(2-Methyl-but-2-enoylamino)-pyridine-2-carboxyli...)
Show SMILES C\C=C(/C)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-3-9(2)12(19)17-10-5-4-6-15-11(10)13(20)18-14-16-7-8-21-14/h3-8H,1-2H3,(H,17,19)(H,16,18,20)/b9-3+
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n/an/a 280n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129657
PNG
(3-(2-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-5-2-1-4-10(11)14(22)20-12-6-3-7-18-13(12)15(23)21-16-19-8-9-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a 280n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129669
PNG
(3-(5-Methyl-hex-4-enoylamino)-pyridine-2-carboxyli...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C16H18N4O2S/c1-11(2)5-3-7-13(21)19-12-6-4-8-17-14(12)15(22)20-16-18-9-10-23-16/h4-6,8-10H,3,7H2,1-2H3,(H,19,21)(H,18,20,22)
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n/an/a 310n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129635
PNG
(3-Formylamino-pyridine-2-carboxylic acid thiazol-2...)
Show SMILES O=CNc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C10H8N4O2S/c15-6-13-7-2-1-3-11-8(7)9(16)14-10-12-4-5-17-10/h1-6H,(H,13,15)(H,12,14,16)
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n/an/a 320n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129649
PNG
(CHEMBL315098 | Cyclohexanecarboxylic acid 2-(thiaz...)
Show SMILES O=C(Oc1cccnc1C(=O)Nc1nccs1)C1CCCCC1
Show InChI InChI=1S/C16H17N3O3S/c20-14(19-16-18-9-10-23-16)13-12(7-4-8-17-13)22-15(21)11-5-2-1-3-6-11/h4,7-11H,1-3,5-6H2,(H,18,19,20)
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n/an/a 320n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129635
PNG
(3-Formylamino-pyridine-2-carboxylic acid thiazol-2...)
Show SMILES O=CNc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C10H8N4O2S/c15-6-13-7-2-1-3-11-8(7)9(16)14-10-12-4-5-17-10/h1-6H,(H,13,15)(H,12,14,16)
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n/an/a 330n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129670
PNG
(3-(2,2,2-Trifluoro-acetylamino)-pyridine-2-carboxy...)
Show SMILES FC(F)(F)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C11H7F3N4O2S/c12-11(13,14)9(20)17-6-2-1-3-15-7(6)8(19)18-10-16-4-5-21-10/h1-5H,(H,17,20)(H,16,18,19)
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Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM17849
PNG
(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Show SMILES CC(C)(C)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O2S/c1-14(2,3)12(20)17-9-5-4-6-15-10(9)11(19)18-13-16-7-8-21-13/h4-8H,1-3H3,(H,17,20)(H,16,18,19)
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n/an/a 340n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129672
PNG
(3-Propionylamino-pyridine-2-carboxylic acid thiazo...)
Show SMILES CCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C12H12N4O2S/c1-2-9(17)15-8-4-3-5-13-10(8)11(18)16-12-14-6-7-19-12/h3-7H,2H2,1H3,(H,15,17)(H,14,16,18)
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n/an/a 350n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129656
PNG
(3-Hexanoylamino-pyridine-2-carboxylic acid thiazol...)
Show SMILES CCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C15H18N4O2S/c1-2-3-4-7-12(20)18-11-6-5-8-16-13(11)14(21)19-15-17-9-10-22-15/h5-6,8-10H,2-4,7H2,1H3,(H,18,20)(H,17,19,21)
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n/an/a 380n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129650
PNG
(CHEMBL314448 | Propionic acid 2-(thiazol-2-ylcarba...)
Show SMILES CCC(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C12H11N3O3S/c1-2-9(16)18-8-4-3-5-13-10(8)11(17)15-12-14-6-7-19-12/h3-7H,2H2,1H3,(H,14,15,17)
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n/an/a 380n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129663
PNG
(3-But-3-enoylamino-pyridine-2-carboxylic acid thia...)
Show SMILES C=CCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C13H12N4O2S/c1-2-4-10(18)16-9-5-3-6-14-11(9)12(19)17-13-15-7-8-20-13/h2-3,5-8H,1,4H2,(H,16,18)(H,15,17,19)
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n/an/a 380n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129641
PNG
(2-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES C\C=C(/C)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-3-9(2)13(19)20-10-5-4-6-15-11(10)12(18)17-14-16-7-8-21-14/h3-8H,1-2H3,(H,16,17,18)/b9-3+
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n/an/a 390n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129666
PNG
(3-Phenylacetylamino-pyridine-2-carboxylic acid thi...)
Show SMILES O=C(Cc1ccccc1)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H14N4O2S/c22-14(11-12-5-2-1-3-6-12)20-13-7-4-8-18-15(13)16(23)21-17-19-9-10-24-17/h1-10H,11H2,(H,20,22)(H,19,21,23)
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n/an/a 400n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129646
PNG
(3-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-9(2)8-11(18)20-10-4-3-5-15-12(10)13(19)17-14-16-6-7-21-14/h3-8H,1-2H3,(H,16,17,19)
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n/an/a 490n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129642
PNG
(CHEMBL86427 | Phenyl-acetic acid 2-(thiazol-2-ylca...)
Show SMILES O=C(Cc1ccccc1)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H13N3O3S/c21-14(11-12-5-2-1-3-6-12)23-13-7-4-8-18-15(13)16(22)20-17-19-9-10-24-17/h1-10H,11H2,(H,19,20,22)
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n/an/a 540n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM17849
PNG
(3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...)
Show SMILES CC(C)(C)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O2S/c1-14(2,3)12(20)17-9-5-4-6-15-10(9)11(19)18-13-16-7-8-21-13/h4-8H,1-3H3,(H,17,20)(H,16,18,19)
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n/an/a 540n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129675
PNG
(2-Methoxy-benzoic acid 2-(thiazol-2-ylcarbamoyl)-p...)
Show SMILES COc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H13N3O4S/c1-23-12-6-3-2-5-11(12)16(22)24-13-7-4-8-18-14(13)15(21)20-17-19-9-10-25-17/h2-10H,1H3,(H,19,20,21)
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n/an/a 550n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129638
PNG
(3-Nitro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyr...)
Show SMILES [O-][N+](=O)c1cccc(c1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10N4O5S/c21-14(19-16-18-7-8-26-16)13-12(5-2-6-17-13)25-15(22)10-3-1-4-11(9-10)20(23)24/h1-9H,(H,18,19,21)
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n/an/a 600n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129669
PNG
(3-(5-Methyl-hex-4-enoylamino)-pyridine-2-carboxyli...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C16H18N4O2S/c1-11(2)5-3-7-13(21)19-12-6-4-8-17-14(12)15(22)20-16-18-9-10-23-16/h4-6,8-10H,3,7H2,1-2H3,(H,19,21)(H,18,20,22)
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n/an/a 610n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129656
PNG
(3-Hexanoylamino-pyridine-2-carboxylic acid thiazol...)
Show SMILES CCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C15H18N4O2S/c1-2-3-4-7-12(20)18-11-6-5-8-16-13(11)14(21)19-15-17-9-10-22-15/h5-6,8-10H,2-4,7H2,1H3,(H,18,20)(H,17,19,21)
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n/an/a 620n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129636
PNG
(2,2-Dimethyl-propionic acid 2-(thiazol-2-ylcarbamo...)
Show SMILES CC(C)(C)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H15N3O3S/c1-14(2,3)12(19)20-9-5-4-6-15-10(9)11(18)17-13-16-7-8-21-13/h4-8H,1-3H3,(H,16,17,18)
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n/an/a 680n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129664
PNG
(3-(3-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1cccc(c1)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-4-1-3-10(9-11)14(22)20-12-5-2-6-18-13(12)15(23)21-16-19-7-8-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a 710n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129640
PNG
(3-(3-Methyl-but-2-enoylamino)-pyridine-2-carboxyli...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-9(2)8-11(19)17-10-4-3-5-15-12(10)13(20)18-14-16-6-7-21-14/h3-8H,1-2H3,(H,17,19)(H,16,18,20)
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n/an/a 770n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129636
PNG
(2,2-Dimethyl-propionic acid 2-(thiazol-2-ylcarbamo...)
Show SMILES CC(C)(C)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H15N3O3S/c1-14(2,3)12(19)20-9-5-4-6-15-10(9)11(18)17-13-16-7-8-21-13/h4-8H,1-3H3,(H,16,17,18)
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n/an/a 780n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129666
PNG
(3-Phenylacetylamino-pyridine-2-carboxylic acid thi...)
Show SMILES O=C(Cc1ccccc1)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H14N4O2S/c22-14(11-12-5-2-1-3-6-12)20-13-7-4-8-18-15(13)16(23)21-17-19-9-10-24-17/h1-10H,11H2,(H,20,22)(H,19,21,23)
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n/an/a 820n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129655
PNG
(2-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-5-2-1-4-10(11)15(22)23-12-6-3-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 830n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129659
PNG
(3-(Cyclohexanecarbonyl-amino)-pyridine-2-carboxyli...)
Show SMILES O=C(Nc1cccnc1C(=O)Nc1nccs1)C1CCCCC1
Show InChI InChI=1S/C16H18N4O2S/c21-14(11-5-2-1-3-6-11)19-12-7-4-8-17-13(12)15(22)20-16-18-9-10-23-16/h4,7-11H,1-3,5-6H2,(H,19,21)(H,18,20,22)
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n/an/a 870n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129658
PNG
(2-Iodo-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyri...)
Show SMILES Ic1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10IN3O3S/c17-11-5-2-1-4-10(11)15(22)23-12-6-3-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 890n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129652
PNG
(3-Benzoylamino-pyridine-2-carboxylic acid thiazol-...)
Show SMILES O=C(Nc1cccnc1C(=O)Nc1nccs1)c1ccccc1
Show InChI InChI=1S/C16H12N4O2S/c21-14(11-5-2-1-3-6-11)19-12-7-4-8-17-13(12)15(22)20-16-18-9-10-23-16/h1-10H,(H,19,21)(H,18,20,22)
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n/an/a 890n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129639
PNG
(3-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1cccc(c1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-4-1-3-10(9-11)15(22)23-12-5-2-6-18-13(12)14(21)20-16-19-7-8-24-16/h1-9H,(H,19,20,21)
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n/an/a 950n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129637
PNG
(CHEMBL315903 | Hexanoic acid 2-(thiazol-2-ylcarbam...)
Show SMILES CCCCCC(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C15H17N3O3S/c1-2-3-4-7-12(19)21-11-6-5-8-16-13(11)14(20)18-15-17-9-10-22-15/h5-6,8-10H,2-4,7H2,1H3,(H,17,18,20)
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n/an/a 1.02E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129671
PNG
(Benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-y...)
Show SMILES O=C(Nc1nccs1)c1ncccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C16H11N3O3S/c20-14(19-16-18-9-10-23-16)13-12(7-4-8-17-13)22-15(21)11-5-2-1-3-6-11/h1-10H,(H,18,19,20)
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n/an/a 1.03E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129644
PNG
(4-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1ccc(cc1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-5-3-10(4-6-11)15(22)23-12-2-1-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 1.10E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129671
PNG
(Benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-y...)
Show SMILES O=C(Nc1nccs1)c1ncccc1OC(=O)c1ccccc1
Show InChI InChI=1S/C16H11N3O3S/c20-14(19-16-18-9-10-23-16)13-12(7-4-8-17-13)22-15(21)11-5-2-1-3-6-11/h1-10H,(H,18,19,20)
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n/an/a 1.22E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129658
PNG
(2-Iodo-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyri...)
Show SMILES Ic1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10IN3O3S/c17-11-5-2-1-4-10(11)15(22)23-12-6-3-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 1.30E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129647
PNG
(3-(4-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1ccc(cc1)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-5-3-10(4-6-11)14(22)20-12-2-1-7-18-13(12)15(23)21-16-19-8-9-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a 1.36E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129651
PNG
(2-Acetoxy-benzoic acid 2-(thiazol-2-ylcarbamoyl)-p...)
Show SMILES CC(=O)Oc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C18H13N3O5S/c1-11(22)25-13-6-3-2-5-12(13)17(24)26-14-7-4-8-19-15(14)16(23)21-18-20-9-10-27-18/h2-10H,1H3,(H,20,21,23)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129675
PNG
(2-Methoxy-benzoic acid 2-(thiazol-2-ylcarbamoyl)-p...)
Show SMILES COc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C17H13N3O4S/c1-23-12-6-3-2-5-11(12)16(22)24-13-7-4-8-18-14(13)15(21)20-17-19-9-10-25-17/h2-10H,1H3,(H,19,20,21)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129653
PNG
(3-Amino-pyridine-2-carboxylic acid thiazol-2-ylami...)
Show SMILES Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C9H8N4OS/c10-6-2-1-3-11-7(6)8(14)13-9-12-4-5-15-9/h1-5H,10H2,(H,12,13,14)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129645
PNG
(3-Methoxy-2-nitro-benzoic acid 2-(thiazol-2-ylcarb...)
Show SMILES COc1cccc(C(=O)Oc2cccnc2C(=O)Nc2nccs2)c1[N+]([O-])=O
Show InChI InChI=1S/C17H12N4O6S/c1-26-12-5-2-4-10(14(12)21(24)25)16(23)27-11-6-3-7-18-13(11)15(22)20-17-19-8-9-28-17/h2-9H,1H3,(H,19,20,22)
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n/an/a 1.70E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129637
PNG
(CHEMBL315903 | Hexanoic acid 2-(thiazol-2-ylcarbam...)
Show SMILES CCCCCC(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C15H17N3O3S/c1-2-3-4-7-12(19)21-11-6-5-8-16-13(11)14(20)18-15-17-9-10-22-15/h5-6,8-10H,2-4,7H2,1H3,(H,17,18,20)
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n/an/a 1.74E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129667
PNG
(3-Hydroxy-pyridine-2-carboxylic acid thiazol-2-yla...)
Show SMILES Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C9H7N3O2S/c13-6-2-1-3-10-7(6)8(14)12-9-11-4-5-15-9/h1-5,13H,(H,11,12,14)
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n/an/a 1.87E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129643
PNG
(CHEMBL89523 | [2-(Thiazol-2-ylcarbamoyl)-pyridin-3...)
Show SMILES CC(C)COC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-9(2)8-21-14(20)17-10-4-3-5-15-11(10)12(19)18-13-16-6-7-22-13/h3-7,9H,8H2,1-2H3,(H,17,20)(H,16,18,19)
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n/an/a 1.92E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129662
PNG
(3-(2-Methoxy-phenyl)-acrylic acid 2-(thiazol-2-ylc...)
Show SMILES COc1ccccc1\C=C\C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C19H15N3O4S/c1-25-14-6-3-2-5-13(14)8-9-16(23)26-15-7-4-10-20-17(15)18(24)22-19-21-11-12-27-19/h2-12H,1H3,(H,21,22,24)/b9-8+
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n/an/a 2.10E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129673
PNG
(2-Nitro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyr...)
Show SMILES [O-][N+](=O)c1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10N4O5S/c21-14(19-16-18-8-9-26-16)13-12(6-3-7-17-13)25-15(22)10-4-1-2-5-11(10)20(23)24/h1-9H,(H,18,19,21)
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n/an/a 2.10E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129649
PNG
(CHEMBL315098 | Cyclohexanecarboxylic acid 2-(thiaz...)
Show SMILES O=C(Oc1cccnc1C(=O)Nc1nccs1)C1CCCCC1
Show InChI InChI=1S/C16H17N3O3S/c20-14(19-16-18-9-10-23-16)13-12(7-4-8-17-13)22-15(21)11-5-2-1-3-6-11/h4,7-11H,1-3,5-6H2,(H,18,19,20)
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n/an/a 2.39E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129668
PNG
(3-Bromo-4-fluoro-benzoic acid 2-(thiazol-2-ylcarba...)
Show SMILES Fc1ccc(cc1Br)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H9BrFN3O3S/c17-10-8-9(3-4-11(10)18)15(23)24-12-2-1-5-19-13(12)14(22)21-16-20-6-7-25-16/h1-8H,(H,20,21,22)
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n/an/a 2.50E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129646
PNG
(3-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6](=O)-[#8]-c1cccnc1-[#6](=O)-[#7]-c1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-9(2)8-11(18)20-10-4-3-5-15-12(10)13(19)17-14-16-6-7-21-14/h3-8H,1-2H3,(H,16,17,19)
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n/an/a 2.60E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129645
PNG
(3-Methoxy-2-nitro-benzoic acid 2-(thiazol-2-ylcarb...)
Show SMILES COc1cccc(C(=O)Oc2cccnc2C(=O)Nc2nccs2)c1[N+]([O-])=O
Show InChI InChI=1S/C17H12N4O6S/c1-26-12-5-2-4-10(14(12)21(24)25)16(23)27-11-6-3-7-18-13(11)15(22)20-17-19-8-9-28-17/h2-9H,1H3,(H,19,20,22)
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n/an/a 3.02E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM17847
PNG
(CHEMBL327579 | pyridine-2-carboxylic acid inhibito...)
Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)
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n/an/a 3.35E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129668
PNG
(3-Bromo-4-fluoro-benzoic acid 2-(thiazol-2-ylcarba...)
Show SMILES Fc1ccc(cc1Br)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H9BrFN3O3S/c17-10-8-9(3-4-11(10)18)15(23)24-12-2-1-5-19-13(12)14(22)21-16-20-6-7-25-16/h1-8H,(H,20,21,22)
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n/an/a 3.40E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129641
PNG
(2-Methyl-but-2-enoic acid 2-(thiazol-2-ylcarbamoyl...)
Show SMILES C\C=C(/C)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H13N3O3S/c1-3-9(2)13(19)20-10-5-4-6-15-11(10)12(18)17-14-16-7-8-21-14/h3-8H,1-2H3,(H,16,17,18)/b9-3+
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n/an/a 4.40E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129660
PNG
(3-(3-Methyl-but-3-enoylamino)-pyridine-2-carboxyli...)
Show SMILES CC(=C)CC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-9(2)8-11(19)17-10-4-3-5-15-12(10)13(20)18-14-16-6-7-21-14/h3-7H,1,8H2,2H3,(H,17,19)(H,16,18,20)
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n/an/a 4.67E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129667
PNG
(3-Hydroxy-pyridine-2-carboxylic acid thiazol-2-yla...)
Show SMILES Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C9H7N3O2S/c13-6-2-1-3-10-7(6)8(14)12-9-11-4-5-15-9/h1-5,13H,(H,11,12,14)
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n/an/a 4.86E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129670
PNG
(3-(2,2,2-Trifluoro-acetylamino)-pyridine-2-carboxy...)
Show SMILES FC(F)(F)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C11H7F3N4O2S/c12-11(13,14)9(20)17-6-2-1-3-15-7(6)8(19)18-10-16-4-5-21-10/h1-5H,(H,17,20)(H,16,18,19)
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n/an/a 4.92E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129661
PNG
(CHEMBL89671 | N-(thiazol-2-yl)picolinamide | Pyrid...)
Show SMILES O=C(Nc1nccs1)c1ccccn1
Show InChI InChI=1S/C9H7N3OS/c13-8(7-3-1-2-4-10-7)12-9-11-5-6-14-9/h1-6H,(H,11,12,13)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129650
PNG
(CHEMBL314448 | Propionic acid 2-(thiazol-2-ylcarba...)
Show SMILES CCC(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C12H11N3O3S/c1-2-9(16)18-8-4-3-5-13-10(8)11(17)15-12-14-6-7-19-12/h3-7H,2H2,1H3,(H,14,15,17)
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n/an/a 5.40E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129661
PNG
(CHEMBL89671 | N-(thiazol-2-yl)picolinamide | Pyrid...)
Show SMILES O=C(Nc1nccs1)c1ccccn1
Show InChI InChI=1S/C9H7N3OS/c13-8(7-3-1-2-4-10-7)12-9-11-5-6-14-9/h1-6H,(H,11,12,13)
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n/an/a 7.00E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129676
PNG
(Acetic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-yl...)
Show SMILES CC(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C11H9N3O3S/c1-7(15)17-8-3-2-4-12-9(8)10(16)14-11-13-5-6-18-11/h2-6H,1H3,(H,13,14,16)
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n/an/a 8.20E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129662
PNG
(3-(2-Methoxy-phenyl)-acrylic acid 2-(thiazol-2-ylc...)
Show SMILES COc1ccccc1\C=C\C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C19H15N3O4S/c1-25-14-6-3-2-5-13(14)8-9-16(23)26-15-7-4-10-20-17(15)18(24)22-19-21-11-12-27-19/h2-12H,1H3,(H,21,22,24)/b9-8+
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n/an/a 9.90E+3n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129674
PNG
(3-(2-Methyl-but-2-enoylamino)-pyridine-2-carboxyli...)
Show SMILES C\C=C(/C)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H14N4O2S/c1-3-9(2)12(19)17-10-5-4-6-15-11(10)13(20)18-14-16-7-8-21-14/h3-8H,1-2H3,(H,17,19)(H,16,18,20)/b9-3+
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n/an/a 1.09E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129651
PNG
(2-Acetoxy-benzoic acid 2-(thiazol-2-ylcarbamoyl)-p...)
Show SMILES CC(=O)Oc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C18H13N3O5S/c1-11(22)25-13-6-3-2-5-12(13)17(24)26-14-7-4-8-19-15(14)16(23)21-18-20-9-10-27-18/h2-10H,1H3,(H,20,21,23)
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n/an/a 1.50E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129655
PNG
(2-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-5-2-1-4-10(11)15(22)23-12-6-3-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 1.60E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50129665
PNG
(2-{2-[2-({1-[2-[2-(2-Amino-propionylamino)-3-(3H-i...)
Show SMILES COC(=O)[C@@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](C)NC(=O)C1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)N
Show InChI InChI=1S/C33H51N11O8/c1-17(2)10-25(33(51)52-6)43-29(47)20(5)39-28(46)19(4)40-31(49)26-8-7-9-44(26)32(50)24(12-22-14-36-16-38-22)42-30(48)23(41-27(45)18(3)34)11-21-13-35-15-37-21/h13-20,23-26H,7-12,34H2,1-6H3,(H,35,37)(H,36,38)(H,39,46)(H,40,49)(H,41,45)(H,42,48)(H,43,47)/t18-,19+,20-,23-,24-,25+,26?/m0/s1
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n/an/a 2.29E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129653
PNG
(3-Amino-pyridine-2-carboxylic acid thiazol-2-ylami...)
Show SMILES Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C9H8N4OS/c10-6-2-1-3-11-7(6)8(14)13-9-12-4-5-15-9/h1-5H,10H2,(H,12,13,14)
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n/an/a 3.28E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129643
PNG
(CHEMBL89523 | [2-(Thiazol-2-ylcarbamoyl)-pyridin-3...)
Show SMILES CC(C)COC(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C14H16N4O3S/c1-9(2)8-21-14(20)17-10-4-3-5-15-11(10)12(19)18-13-16-6-7-22-13/h3-7,9H,8H2,1-2H3,(H,17,20)(H,16,18,19)
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n/an/a 5.37E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129644
PNG
(4-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1ccc(cc1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-5-3-10(4-6-11)15(22)23-12-2-1-7-18-13(12)14(21)20-16-19-8-9-24-16/h1-9H,(H,19,20,21)
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n/an/a 6.20E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129665
PNG
(2-{2-[2-({1-[2-[2-(2-Amino-propionylamino)-3-(3H-i...)
Show SMILES COC(=O)[C@@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@@H](C)NC(=O)C1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)N
Show InChI InChI=1S/C33H51N11O8/c1-17(2)10-25(33(51)52-6)43-29(47)20(5)39-28(46)19(4)40-31(49)26-8-7-9-44(26)32(50)24(12-22-14-36-16-38-22)42-30(48)23(41-27(45)18(3)34)11-21-13-35-15-37-21/h13-20,23-26H,7-12,34H2,1-6H3,(H,35,37)(H,36,38)(H,39,46)(H,40,49)(H,41,45)(H,42,48)(H,43,47)/t18-,19+,20-,23-,24-,25+,26?/m0/s1
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n/an/a 9.51E+4n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129657
PNG
(3-(2-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-5-2-1-4-10(11)14(22)20-12-6-3-7-18-13(12)15(23)21-16-19-8-9-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129647
PNG
(3-(4-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1ccc(cc1)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-5-3-10(4-6-11)14(22)20-12-2-1-7-18-13(12)15(23)21-16-19-8-9-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129638
PNG
(3-Nitro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyr...)
Show SMILES [O-][N+](=O)c1cccc(c1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10N4O5S/c21-14(19-16-18-7-8-26-16)13-12(5-2-6-17-13)25-15(22)10-3-1-4-11(9-10)20(23)24/h1-9H,(H,18,19,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129673
PNG
(2-Nitro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyr...)
Show SMILES [O-][N+](=O)c1ccccc1C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10N4O5S/c21-14(19-16-18-8-9-26-16)13-12(6-3-7-17-13)25-15(22)10-4-1-2-5-11(10)20(23)24/h1-9H,(H,18,19,21)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50113436
PNG
(CHEMBL32838 | fumagillin)
Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](/[#6])-[#6])-[#8]-[#6](=O)\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6](-[#8])=O
Show InChI InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase


(Escherichia coli (strain K12))		BDBM50113436
PNG
(CHEMBL32838 | fumagillin)
Show SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](/[#6])-[#6])-[#8]-[#6](=O)\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6]=[#6]\[#6](-[#8])=O
Show InChI InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24-,25+,26+/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129664
PNG
(3-(3-Fluoro-benzoylamino)-pyridine-2-carboxylic ac...)
Show SMILES Fc1cccc(c1)C(=O)Nc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H11FN4O2S/c17-11-4-1-3-10(9-11)14(22)20-12-5-2-6-18-13(12)15(23)21-16-19-7-8-24-16/h1-9H,(H,20,22)(H,19,21,23)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129652
PNG
(3-Benzoylamino-pyridine-2-carboxylic acid thiazol-...)
Show SMILES O=C(Nc1cccnc1C(=O)Nc1nccs1)c1ccccc1
Show InChI InChI=1S/C16H12N4O2S/c21-14(11-5-2-1-3-6-11)19-12-7-4-8-17-13(12)15(22)20-16-18-9-10-23-16/h1-10H,(H,19,21)(H,18,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129659
PNG
(3-(Cyclohexanecarbonyl-amino)-pyridine-2-carboxyli...)
Show SMILES O=C(Nc1cccnc1C(=O)Nc1nccs1)C1CCCCC1
Show InChI InChI=1S/C16H18N4O2S/c21-14(11-5-2-1-3-6-11)19-12-7-4-8-17-13(12)15(22)20-16-18-9-10-23-16/h4,7-11H,1-3,5-6H2,(H,19,21)(H,18,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Saccharomyces cerevisiae)		BDBM50129639
PNG
(3-Fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-py...)
Show SMILES Fc1cccc(c1)C(=O)Oc1cccnc1C(=O)Nc1nccs1
Show InChI InChI=1S/C16H10FN3O3S/c17-11-4-1-3-10(9-11)15(22)23-12-5-2-6-18-13(12)14(21)20-16-19-7-8-24-16/h1-9H,(H,19,20,21)
PDB

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n/an/a>1.00E+5n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae

J Med Chem 46: 2631-40 (2003)


Article DOI: 10.1021/jm0300532
BindingDB Entry DOI: 10.7270/Q2CF9QTC
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%