BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 466 hits with Last Name = 'anizon' and Initial = 'f'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50268249
PNG
(12,13-[6-Deoxy-6-amino-4-O-methyl-D-mannopyranosyl...)
Show SMILES CO[C@@H]1[C@@H](CN)O[C@@H]2[C@H]([C@H]1O)n1c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n2c4c13 |r|
Show InChI InChI=1S/C27H22N4O5/c1-35-24-15(10-28)36-27-22(23(24)32)30-13-8-4-2-6-11(13)16-18-19(26(34)29-25(18)33)17-12-7-3-5-9-14(12)31(27)21(17)20(16)30/h2-9,15,22-24,27,32H,10,28H2,1H3,(H,29,33,34)/t15-,22+,23-,24-,27-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged human full-length CHK1 expressed in Sf9 cells

Eur J Med Chem 44: 2234-8 (2009)


Article DOI: 10.1016/j.ejmech.2008.05.023
BindingDB Entry DOI: 10.7270/Q2XP74R2
More data for this
Ligand-Target Pair		3D
3D Structure (docked)
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM50605473
PNG
(CHEMBL5186093)
Show SMILES Nc1ccc2cc3cnccc3c([N+]([O-])=O)c2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM50587785
PNG
(CHEMBL5178368)
Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50326438
PNG
(9-trifluoromethyl-1,10-dihydropyrrolo[2,3-a]carbaz...)
Show SMILES FC(F)(F)c1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12
Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)12-3-1-2-10-11-5-4-9-8(7-22)6-20-14(9)15(11)21-13(10)12/h1-7,20-21H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50326436
PNG
(6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12
Show InChI InChI=1S/C15H9BrN2O/c16-11-2-1-3-12-13(11)10-5-4-9-8(7-19)6-17-14(9)15(10)18-12/h1-7,17-18H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 6.80n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50365178
PNG
(CHEMBL1950228)
Show SMILES O=Cc1cn2CCCCn3c4ccccc4c4ccc1c2c34
Show InChI InChI=1S/C19H16N2O/c22-12-13-11-20-9-3-4-10-21-17-6-2-1-5-15(17)16-8-7-14(13)18(20)19(16)21/h1-2,5-8,11-12H,3-4,9-10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His6-tagged PIM1 expressed in Sf21 cells using RSRHSSYPAGT as substrate after 30 mins

Eur J Med Chem 50: 304-10 (2012)


Article DOI: 10.1016/j.ejmech.2012.02.009
BindingDB Entry DOI: 10.7270/Q22N52QX
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Mus musculus)		BDBM50587785
PNG
(CHEMBL5178368)
Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50129948
PNG
(CHEMBL3627997)
Show SMILES O=Cc1cn2CCCCCn3c4ccccc4c4ccc1c2c34
Show InChI InChI=1S/C20H18N2O/c23-13-14-12-21-10-4-1-5-11-22-18-7-3-2-6-16(18)17-9-8-15(14)19(21)20(17)22/h2-3,6-9,12-13H,1,4-5,10-11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Universit£ Clermont Auvergne

Curated by ChEMBL


Assay Description
Inhibition of Pim-1 (unknown origin)

Bioorg Med Chem 23: 7313-23 (2015)


Article DOI: 10.1016/j.bmc.2015.10.031
BindingDB Entry DOI: 10.7270/Q23F4RHC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299249
PNG
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21
Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
US Patent
n/an/a 10n/an/an/an/an/an/a



Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II

US Patent


Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3.

US Patent US8481586 (2013)


BindingDB Entry DOI: 10.7270/Q2ZC81GT
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299249
PNG
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21
Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299249
PNG
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21
Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of human Pim3 using RSRHSSYPAGT as substrate

Eur J Med Chem 56: 225-236 (2012)


Article DOI: 10.1016/j.ejmech.2012.08.029
BindingDB Entry DOI: 10.7270/Q2XK8GTF
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299249
PNG
(1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde...)
Show SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21
Show InChI InChI=1S/C15H10N2O/c18-8-9-7-16-14-10(9)5-6-12-11-3-1-2-4-13(11)17-15(12)14/h1-8,16-17H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3

J Med Chem 52: 6369-81 (2009)


Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))		BDBM50605464
PNG
(CHEMBL5188318)
Show SMILES CSc1ncc2cc3cnccc3c(N)c2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 12n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50326436
PNG
(6-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1cccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c12
Show InChI InChI=1S/C15H9BrN2O/c16-11-2-1-3-12-13(11)10-5-4-9-8(7-19)6-17-14(9)15(10)18-12/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 12.4n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50365178
PNG
(CHEMBL1950228)
Show SMILES O=Cc1cn2CCCCn3c4ccccc4c4ccc1c2c34
Show InChI InChI=1S/C19H16N2O/c22-12-13-11-20-9-3-4-10-21-17-6-2-1-5-15(17)16-8-7-14(13)18(20)19(16)21/h1-2,5-8,11-12H,3-4,9-10H2
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His6-tagged PIM3 expressed in Sf21 cells using RSRHSSYPAGT as substrate after 30 mins

Eur J Med Chem 50: 304-10 (2012)


Article DOI: 10.1016/j.ejmech.2012.02.009
BindingDB Entry DOI: 10.7270/Q22N52QX
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50587785
PNG
(CHEMBL5178368)
Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50216159
PNG
(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Show SMILES Oc1ccc2[nH]c3c4cccn4c4C(=O)NC(=O)c4c3c2c1
Show InChI InChI=1S/C16H9N3O3/c20-7-3-4-9-8(6-7)11-12-14(16(22)18-15(12)21)19-5-1-2-10(19)13(11)17-9/h1-6,17,20H,(H,18,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1

Bioorg Med Chem 15: 5965-80 (2007)


Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50326438
PNG
(9-trifluoromethyl-1,10-dihydropyrrolo[2,3-a]carbaz...)
Show SMILES FC(F)(F)c1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12
Show InChI InChI=1S/C16H9F3N2O/c17-16(18,19)12-3-1-2-10-11-5-4-9-8(7-22)6-20-14(9)15(11)21-13(10)12/h1-7,20-21H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Mus musculus)		BDBM50148458
PNG
(CHEMBL4778413)
Show SMILES CNc1ncc2cc3cnccc3c([N+]([O-])=O)c2n1
Show InChI InChI=1S/C18H18N2O4S/c1-19-17(21)15-8-11-16(25-15)12(9-20(2)18(11)22)10-5-6-13(23-3)14(7-10)24-4/h5-9H,1-4H3,(H,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 18n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl

Citation and Details

Article DOI: 10.1016/j.ejmech.2019.01.052
BindingDB Entry DOI: 10.7270/Q2BZ69NW
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50220067
PNG
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O
Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1

Eur J Med Chem 43: 282-92 (2008)


Article DOI: 10.1016/j.ejmech.2007.03.026
BindingDB Entry DOI: 10.7270/Q2H70FKP
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50055958
PNG
(CHEMBL3326555)
Show SMILES [O-][N+](=O)c1cc2[nH]ncc2c2c1ncc1ccccc21
Show InChI InChI=1S/C14H8N4O2/c19-18(20)12-5-11-10(7-16-17-11)13-9-4-2-1-3-8(9)6-15-14(12)13/h1-7H,(H,16,17)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.bmcl.2022.128914
BindingDB Entry DOI: 10.7270/Q20K2DHX
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50220067
PNG
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O
Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1 expressed in Sf9 cells

J Med Chem 50: 4669-80 (2007)


Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50055958
PNG
(CHEMBL3326555)
Show SMILES [O-][N+](=O)c1cc2[nH]ncc2c2c1ncc1ccccc21
Show InChI InChI=1S/C14H8N4O2/c19-18(20)12-5-11-10(7-16-17-11)13-9-4-2-1-3-8(9)6-15-14(12)13/h1-7H,(H,16,17)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of full-length human PIM3 using RSRHSSYPAGT as substrate assessed as residual kinase activity after 30 mins in presence of [gamma-33P]ATP

Bioorg Med Chem 22: 4704-10 (2014)


Article DOI: 10.1016/j.bmc.2014.07.011
BindingDB Entry DOI: 10.7270/Q2MS3VD0
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Mus musculus)		BDBM50605473
PNG
(CHEMBL5186093)
Show SMILES Nc1ccc2cc3cnccc3c([N+]([O-])=O)c2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50249773
PNG
(CHEMBL4763099)
Show SMILES CN1CCN(CCCNc2ncc3cc4cnccc4c(N)c3n2)CC1
Show InChI InChI=1S/C13H16N2O3S/c1-9(2)19(17,18)14-11-5-6-12-10(8-11)4-7-13(16)15(12)3/h4-9,14H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2019.01.052
BindingDB Entry DOI: 10.7270/Q2BZ69NW
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50220067
PNG
(11H-2,5,11-triaza-benzo[a]trindene-1,3,4,6-tetraon...)
Show SMILES O=c1[nH]c(=O)c2c1c1[nH]c3ccccc3c1c1c2c(=O)[nH]c1=O
Show InChI InChI=1S/C16H7N3O4/c20-13-8-7-5-3-1-2-4-6(5)17-12(7)11-10(9(8)14(21)18-13)15(22)19-16(11)23/h1-4,17H,(H,18,20,21)(H,19,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Universit£ Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1

Bioorg Med Chem 16: 4419-30 (2008)


Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50178616
PNG
(CHEMBL3814423)
Show SMILES c1n[nH]c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21
Show InChI InChI=1S/C19H12N4/c1-3-7-13-10(5-1)15-12-9-20-23-17(12)16-11-6-2-4-8-14(11)22-19(16)18(15)21-13/h1-9,21-22H,(H,20,23)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Universit£ Clermont Auvergne

Curated by ChEMBL


Assay Description
Inhibition of human full length (His)6-tagged Pim-3 expressed in insect Sf21 cells using RSRHSSYPAGT as substrate measured for 30 mins by [gamma-33P]...

Bioorg Med Chem 24: 3116-24 (2016)


Article DOI: 10.1016/j.bmc.2016.05.032
BindingDB Entry DOI: 10.7270/Q2ZG6V50
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50220064
PNG
(4,7,11-trihydroxybenzo[a]pyrrolo[3,4-c]carbazole-1...)
Show SMILES Oc1ccc2[nH]c3c(c4C(=O)NC(=O)c4c4c(O)ccc(O)c34)c2c1
Show InChI InChI=1S/C18H10N2O5/c21-6-1-2-8-7(5-6)11-14-15(18(25)20-17(14)24)12-9(22)3-4-10(23)13(12)16(11)19-8/h1-5,19,21-23H,(H,20,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1 expressed in Sf9 cells

J Med Chem 50: 4669-80 (2007)


Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50249769
PNG
(CHEMBL4748345)
Show SMILES Nc1c2ccncc2cc2cnc(NCCCN3CCOCC3)nc12
Show InChI InChI=1S/C16H14N2O3S/c1-18-15-9-8-14(11-12(15)7-10-16(18)19)22(20,21)17-13-5-3-2-4-6-13/h2-11,17H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 23n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2019.01.052
BindingDB Entry DOI: 10.7270/Q2BZ69NW
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50376170
PNG
(CHEMBL265446)
Show SMILES O=C1NCc2c1c1C(=O)NC(=O)c1c1c2[nH]c2ccccc12
Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)13-9(6-3-1-2-4-8(6)18-13)11-12(10)16(22)19-15(11)21/h1-4,18H,5H2,(H,17,20)(H,19,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Universit£ Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1

Bioorg Med Chem 16: 4419-30 (2008)


Article DOI: 10.1016/j.bmc.2008.02.061
BindingDB Entry DOI: 10.7270/Q24Q7VV9
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50326441
PNG
(9-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12
Show InChI InChI=1S/C15H9BrN2O/c16-12-3-1-2-10-11-5-4-9-8(7-19)6-17-14(9)15(11)18-13(10)12/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50216171
PNG
(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Show SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1cccn21
Show InChI InChI=1S/C16H9N3O2/c20-15-12-11-8-4-1-2-5-9(8)17-13(11)10-6-3-7-19(10)14(12)16(21)18-15/h1-7,17H,(H,18,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1

Bioorg Med Chem 15: 5965-80 (2007)


Article DOI: 10.1016/j.bmc.2007.05.073
BindingDB Entry DOI: 10.7270/Q2KW5FR0
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Homo sapiens (Human))		BDBM50347798
PNG
(CHEMBL1802410)
Show SMILES Nc1ncc(I)c(n1)-c1c[nH]c2c(N)cccc12
Show InChI InChI=1S/C12H10IN5/c13-8-5-17-12(15)18-10(8)7-4-16-11-6(7)2-1-3-9(11)14/h1-5,16H,14H2,(H2,15,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Clermont Universite£

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate

J Med Chem 54: 4474-89 (2011)


Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50129948
PNG
(CHEMBL3627997)
Show SMILES O=Cc1cn2CCCCCn3c4ccccc4c4ccc1c2c34
Show InChI InChI=1S/C20H18N2O/c23-13-14-12-21-10-4-1-5-11-22-18-7-3-2-6-16(18)17-9-8-15(14)19(21)20(17)22/h2-3,6-9,12-13H,1,4-5,10-11H2
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 26n/an/an/an/an/an/a



Universit£ Clermont Auvergne

Curated by ChEMBL


Assay Description
Inhibition of Pim-3 (unknown origin)

Bioorg Med Chem 23: 7313-23 (2015)


Article DOI: 10.1016/j.bmc.2015.10.031
BindingDB Entry DOI: 10.7270/Q23F4RHC
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50220072
PNG
(11-hydroxybenzo[a]pyrrolo[3,4-c]carbazole-1,3,4,7(...)
Show SMILES Oc1ccc2nc3c(c2c1)c1c(c2c3c(O)ccc2=O)c(=O)[nH]c1=O
Show InChI InChI=1S/C18H8N2O5/c21-6-1-2-8-7(5-6)11-14-15(18(25)20-17(14)24)12-9(22)3-4-10(23)13(12)16(11)19-8/h1-5,21,23H,(H,20,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Université Blaise Pascal

Curated by ChEMBL


Assay Description
Inhibition of human Chk1 expressed in Sf9 cells

J Med Chem 50: 4669-80 (2007)


Article DOI: 10.1021/jm070664k
BindingDB Entry DOI: 10.7270/Q2P55N7F
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50185005
PNG
(CHEMBL3823483)
Show SMILES Nc1ncc2cc3cnccc3c(N)c2n1
Show InChI InChI=1S/C11H9N5/c12-9-8-1-2-14-4-6(8)3-7-5-15-11(13)16-10(7)9/h1-5H,12H2,(H2,13,15,16)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
UniChem

Similars
Article
PubMed
n/an/a 28n/an/an/an/an/an/a



Universit£ Clermont Auvergne

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 30 mins in presen...

Eur J Med Chem 118: 170-7 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.004
BindingDB Entry DOI: 10.7270/Q29888XM
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50587785
PNG
(CHEMBL5178368)
Show SMILES CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 29n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Homo sapiens (Human))		BDBM50347802
PNG
(CHEMBL1802406)
Show SMILES Nc1ncc(I)c(n1)-c1c[nH]c2ccccc12
Show InChI InChI=1S/C12H9IN4/c13-9-6-16-12(14)17-11(9)8-5-15-10-4-2-1-3-7(8)10/h1-6,15H,(H2,14,16,17)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Clermont Universite£

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate

J Med Chem 54: 4474-89 (2011)


Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50326439
PNG
(CHEMBL1243128 | Methyl 3-formyl-1,10-dihydropyrrol...)
Show SMILES COC(=O)c1cccc2c3ccc4c(C=O)c[nH]c4c3[nH]c12
Show InChI InChI=1S/C17H12N2O3/c1-22-17(21)13-4-2-3-11-12-6-5-10-9(8-20)7-18-15(10)16(12)19-14(11)13/h2-8,18-19H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50589508
PNG
(CHEMBL5201872)
Show SMILES [O-][N+](=O)c1cc2[nH]nc(C=C)c2c2c3ccccc3cnc12
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 31n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.bmcl.2022.128914
BindingDB Entry DOI: 10.7270/Q20K2DHX
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50326441
PNG
(9-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1cccc2c1[nH]c1c2ccc2c(C=O)c[nH]c12
Show InChI InChI=1S/C15H9BrN2O/c16-12-3-1-2-10-11-5-4-9-8(7-19)6-17-14(9)15(11)18-13(10)12/h1-7,17-18H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Homo sapiens (Human))		BDBM50347793
PNG
(CHEMBL1802966)
Show SMILES Nc1ncc(I)c(n1)-c1c[nH]c2cc(Br)ccc12
Show InChI InChI=1S/C12H8BrIN4/c13-6-1-2-7-8(4-16-10(7)3-6)11-9(14)5-17-12(15)18-11/h1-5,16H,(H2,15,17,18)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Clermont Universite£

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrate

J Med Chem 54: 4474-89 (2011)


Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50432942
PNG
(CHEMBL2377721)
Show SMILES Nc1cc2cn[nH]c2c2cc[nH]c12
Show InChI InChI=1S/C9H8N4/c10-7-3-5-4-12-13-8(5)6-1-2-11-9(6)7/h1-4,11H,10H2,(H,12,13)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 33n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of human full length Pim-3 using RSRHSSYPAGT as substrate assessed as residual activity after 30 mins in presence of [gamma-33P]ATP

Bioorg Med Chem Lett 23: 2298-301 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.074
BindingDB Entry DOI: 10.7270/Q26111PK
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50347793
PNG
(CHEMBL1802966)
Show SMILES Nc1ncc(I)c(n1)-c1c[nH]c2cc(Br)ccc12
Show InChI InChI=1S/C12H8BrIN4/c13-6-1-2-7-8(4-16-10(7)3-6)11-9(14)5-17-12(15)18-11/h1-5,16H,(H2,15,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Clermont Universite£

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation counting

J Med Chem 54: 4474-89 (2011)


Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P
More data for this
Ligand-Target Pair
Dual specificity protein kinase CLK1


(Mus musculus)		BDBM50605464
PNG
(CHEMBL5188318)
Show SMILES CSc1ncc2cc3cnccc3c(N)c2n1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 37n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114369
BindingDB Entry DOI: 10.7270/Q2HQ440P
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)		BDBM50347792
PNG
(CHEMBL1802967)
Show SMILES Nc1ncc(I)c(n1)-c1c[nH]c2c(Br)cccc12
Show InChI InChI=1S/C12H8BrIN4/c13-8-3-1-2-6-7(4-16-10(6)8)11-9(14)5-17-12(15)18-11/h1-5,16H,(H2,15,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 39n/an/an/an/an/an/a



Clermont Universite£

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation counting

J Med Chem 54: 4474-89 (2011)


Article DOI: 10.1021/jm200464w
BindingDB Entry DOI: 10.7270/Q2ZW1M8P
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM50436564
PNG
(CHEMBL2397523)
Show SMILES [O-][N+](=O)c1cc2n[nH]cc2c2c1[nH]c1ccccc21
Show InChI InChI=1S/C13H8N4O2/c18-17(19)11-5-10-8(6-14-16-10)12-7-3-1-2-4-9(7)15-13(11)12/h1-6,15H,(H,14,16)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of human PIM1 using RSRHSSYPAGT as substrate after 30 mins

Bioorg Med Chem 21: 4102-11 (2013)


Article DOI: 10.1016/j.bmc.2013.05.011
BindingDB Entry DOI: 10.7270/Q2F76DZV
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50326439
PNG
(CHEMBL1243128 | Methyl 3-formyl-1,10-dihydropyrrol...)
Show SMILES COC(=O)c1cccc2c3ccc4c(C=O)c[nH]c4c3[nH]c12
Show InChI InChI=1S/C17H12N2O3/c1-22-17(21)13-4-2-3-11-12-6-5-10-9(8-20)7-18-15(10)16(12)19-14(11)13/h2-8,18-19H,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Clermont Université

Curated by ChEMBL


Assay Description
Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 mins

Bioorg Med Chem 18: 6865-73 (2010)


Article DOI: 10.1016/j.bmc.2010.07.036
BindingDB Entry DOI: 10.7270/Q2PK0GBZ
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299245
PNG
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1
Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
US Patent
n/an/a 40n/an/an/an/an/an/a



Centre National de la Recherche Scientifique; Universite Blaise Pascal-Clermont-Ferrand II

US Patent


Assay Description
Inhibition assay using PIM-1, PIM-2 and PIM-3.

US Patent US8481586 (2013)


BindingDB Entry DOI: 10.7270/Q2ZC81GT
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-3


(Homo sapiens (Human))		BDBM50299245
PNG
(7-Bromo-1,10-dihydropyrrolo[2,3-a]carbazole-3-carb...)
Show SMILES Brc1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1
Show InChI InChI=1S/C15H9BrN2O/c16-9-1-4-13-12(5-9)11-3-2-10-8(7-19)6-17-14(10)15(11)18-13/h1-7,17-18H
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Clermont Universit£

Curated by ChEMBL


Assay Description
Inhibition of Pim-3

J Med Chem 52: 6369-81 (2009)


Article DOI: 10.1021/jm901018f
BindingDB Entry DOI: 10.7270/Q23F4PPS
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 466 total )  |  Next  |  Last  >>
Jump to: