Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088301 ((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088321 (CHEMBL292548 | Dimethyl-(tetrahydro-pyran-4-yl)-{4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088302 (CHEMBL56565 | Dimethyl-(tetrahydro-pyran-4-yl)-(4-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088301 ((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088322 ((4-{[7-(4-Ethoxy-phenyl)-2,3-dihydro-benzo[b]oxepi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088319 (CHEMBL62339 | Dimethyl-(4-{[3-(4-piperidin-1-yl-ph...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088311 (CHEMBL61208 | Dimethyl-(tetrahydro-thiopyran-4-yl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088306 ((1-Ethyl-propyl)-dimethyl-{4-[(7-p-tolyl-2,3-dihyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088312 (CHEMBL62180 | Dimethyl-(4-{[3-(4-pyrrolidin-1-yl-p...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088325 (CHEMBL62598 | Dimethyl-(4-oxo-cyclohexyl)-{4-[(7-p...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088315 ((3-Hydroxy-propyl)-dimethyl-{4-[(7-p-tolyl-2,3-dih...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088320 (1-Methyl-1-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50088301 ((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect of the compound on the binding of [125I]- MCP-1 to C-C chemokine receptor type 2-expressing CHO cells | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088309 (1-Methyl-1-{4-[(7-p-tolyl-2,3-dihydro-benzo[b]oxep...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088303 (1-Methyl-1-(2-{4-[(7-p-tolyl-2,3-dihydro-benzo[b]o...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50324535 (3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088308 (1-Methyl-1-{4-[(7-p-tolyl-3,4-dihydro-naphthalene-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088323 (1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088317 (1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088324 (1-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392055 (CHEMBL2152621) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088318 (1-Methyl-1-{4-[3-(4'-methyl-biphenyl-3-yl)-acryloy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088316 (CHEMBL62454 | Tributyl-{4-[3-(4'-methyl-biphenyl-3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088305 (1-Methyl-1-{4-[(6-p-tolyl-2H-chromene-3-carbonyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4A (Homo sapiens (Human)) | BDBM50324535 (3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM4A (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392059 (CHEMBL2152625) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088307 (CHEMBL292345 | Triethyl-{4-[(7-phenyl-3,4-dihydro-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392111 (CHEMBL2152613) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088313 (1-Methyl-1-(2-{4-[(7-phenyl-3,4-dihydro-naphthalen...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392060 (CHEMBL2152626) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088310 (4-Methyl-4-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392062 (CHEMBL2152628) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392053 (CHEMBL2152620) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392057 (CHEMBL2152623) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392115 (CHEMBL2152617) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392114 (CHEMBL2152616) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392113 (CHEMBL2152615) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM50095454 (CHEMBL3590422) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of JARID1A (unknown origin) using biotinylated H3K9mel peptide after 60 mins by Alpha screen assay | ACS Med Chem Lett 6: 665-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00083 BindingDB Entry DOI: 10.7270/Q2V69MC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392054 (CHEMBL2151055) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392058 (CHEMBL2152624) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392052 (CHEMBL2152619) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM50324535 (3-{[9-(Dimethylamino)nonanoyl](hydroxy)amino}propa...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM4C (unknown origin) using H3K9me3 peptide and 2-oxoglutarate as substrate after 1 hr by FDH-coupled assay | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM50095446 (CHEMBL3590426) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of JARID1A (unknown origin) using biotinylated H3K9mel peptide after 60 mins by Alpha screen assay | ACS Med Chem Lett 6: 665-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00083 BindingDB Entry DOI: 10.7270/Q2V69MC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392056 (CHEMBL2152622) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50440285 (CHEMBL2424816) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of KDM2A (unknown origin) | J Med Chem 56: 7222-31 (2013) Article DOI: 10.1021/jm400624b BindingDB Entry DOI: 10.7270/Q2SB475V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50392116 (CHEMBL2152618) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b... | J Med Chem 55: 5760-73 (2012) Article DOI: 10.1021/jm3002108 BindingDB Entry DOI: 10.7270/Q2WW7JRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM50095451 (CHEMBL3590431) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of JARID1A (unknown origin) using biotinylated H3K9mel peptide after 60 mins by Alpha screen assay | ACS Med Chem Lett 6: 665-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00083 BindingDB Entry DOI: 10.7270/Q2V69MC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50088314 (2-Methyl-1-{4-[(7-phenyl-3,4-dihydro-naphthalene-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Chemical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibitory effect on Chemokine binding to C-C chemokine receptor type 5 using [125I]-RANTES | J Med Chem 43: 2049-63 (2000) BindingDB Entry DOI: 10.7270/Q26D5S75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 5A (Homo sapiens (Human)) | BDBM50095447 (CHEMBL3590427) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Prefectural University of Medicine Curated by ChEMBL | Assay Description Inhibition of JARID1A (unknown origin) using biotinylated H3K9mel peptide after 60 mins by Alpha screen assay | ACS Med Chem Lett 6: 665-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00083 BindingDB Entry DOI: 10.7270/Q2V69MC7 | |||||||||||
More data for this Ligand-Target Pair |
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