Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163679 (3,4‐Dichloro‐1‐benzothiophene...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163680 (3‐Chloro‐N'‐[(1Z)‐2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163683 (N'‐Cyclohexylidene‐3‐hydroxy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163694 (3‐Chloro‐1‐benzothiophene‐...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163681 (3-Chloro‐N'‐[(1E)‐(4‐f...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163683 (N'‐Cyclohexylidene‐3‐hydroxy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163679 (3,4‐Dichloro‐1‐benzothiophene...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163680 (3‐Chloro‐N'‐[(1Z)‐2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 370 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163695 (Benzoylhydrazine, P‐bromo (0151-Hy)) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 390 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163681 (3-Chloro‐N'‐[(1E)‐(4‐f...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163682 (4‐Bromo‐N'‐cyclohexylidenebe...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 610 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163682 (4‐Bromo‐N'‐cyclohexylidenebe...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163685 (2‐(4‐Chloro‐3,5‐dimethylph...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.53E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163686 (2‐(Naphthalen‐1‐yloxy)acetohydra...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163690 (3‐Bromo‐N'‐[(2Z)‐hexan...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163684 (2‐(3‐Chlorophenoxy)propanehydrazide (0...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163689 (3‐Bromo‐N'‐[(2Z)‐hex...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.78E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163691 (1‐(4‐Methoxy‐2,5‐dimethylb...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.15E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163688 (2,4‐Dichloro‐N'‐(1‐pro...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163687 (N'‐[(1E)‐1‐(2H‐1,3R...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.17E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM50106186 (4‐Bromobenzamide (0151-Am) | 4-Bromo-benzami...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | D...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Oregon Health & Science University | Assay Description Gel-based assays were performed by combining 4 無 of OGG1 (62.5 nM) with 1 無 of inhibitor or buffer. Substrate (5 無, 50 nM) was added to bring the ... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM50336507 (4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | D...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163693 (Nialamide) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM81461 (CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-glycosylase/DNA lyase (Homo sapiens (Human)) | BDBM163692 (ISOCARBOXAZID | Isocarboxazid (ICD) | Isocarboxazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Oregon Health & Science University | Assay Description A total of 4 無 of OGG1 (125 nM) was mixed with 1 無 of inhibitor. In a separate tube, 1 無 of freshly prepared 10 mM NaBH3CN (diluted in H2O) was mi... | ACS Chem Biol 10: 2334-43 (2015) Article DOI: 10.1021/acschembio.5b00452 BindingDB Entry DOI: 10.7270/Q22F7M6H | |||||||||||
More data for this Ligand-Target Pair |