Compile Data Set for Download or QSAR

Found 193 hits with Last Name = 'fenton' and Initial = 'rl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor VII (Homo sapiens (Human))	BDBM14593 (3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carb...) Show SMILES CC(C)Nc1nc(Cl)c(-c2cc(N)cc(c2)C(O)=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H26ClN7O4/c1-12(2)30-22-23(34)32(11-18(33)29-10-13-3-5-14(6-4-13)21(27)28)19(20(25)31-22)15-7-16(24(35)36)9-17(26)8-15/h3-9,12H,10-11,26H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)(H,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14543 (2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(N)c2)cc1 Show InChI InChI=1S/C24H26ClN7O2/c25-21-20(16-3-1-4-17(26)11-16)32(24(34)23(31-21)30-18-5-2-6-18)13-19(33)29-12-14-7-9-15(10-8-14)22(27)28/h1,3-4,7-11,18H,2,5-6,12-13,26H2,(H3,27,28)(H,29,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14535 (2-[6-(3-aminophenyl)-5-chloro-2-oxo-3-(propan-2-yl...) Show SMILES CC(C)Nc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C23H26ClN7O2/c1-13(2)29-22-23(33)31(19(20(24)30-22)16-4-3-5-17(25)10-16)12-18(32)28-11-14-6-8-15(9-7-14)21(26)27/h3-10,13H,11-12,25H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14528 (2-[6-(3-aminophenyl)-5-chloro-3-(ethylamino)-2-oxo...) Show SMILES CCNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C22H24ClN7O2/c1-2-27-21-22(32)30(18(19(23)29-21)15-4-3-5-16(24)10-15)12-17(31)28-11-13-6-8-14(9-7-13)20(25)26/h3-10H,2,11-12,24H2,1H3,(H3,25,26)(H,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14563 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-et...) Show SMILES CCc1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C24H27ClN6O2/c1-2-19-21(25)30-23(28-13-12-16-6-4-3-5-7-16)24(33)31(19)15-20(32)29-14-17-8-10-18(11-9-17)22(26)27/h3-11H,2,12-15H2,1H3,(H3,26,27)(H,28,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14520 (N-[(4-carbamimidoylphenyl)methyl]-2-(5-chloro-3-{[...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3cccc(Cl)c3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-8-4-5-18(15-22)13-14-33-27-28(38)36(24(25(30)35-27)20-6-2-1-3-7-20)17-23(37)34-16-19-9-11-21(12-10-19)26(31)32/h1-12,15H,13-14,16-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14519 (N-[(4-carbamimidoylphenyl)methyl]-2-(5-chloro-3-{[...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccc(Cl)cc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-12-8-18(9-13-22)14-15-33-27-28(38)36(24(25(30)35-27)20-4-2-1-3-5-20)17-23(37)34-16-19-6-10-21(11-7-19)26(31)32/h1-13H,14-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<40	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14537 (2-[6-(3-aminophenyl)-5-chloro-2-oxo-3-(pentan-3-yl...) Show SMILES CCC(CC)Nc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C25H30ClN7O2/c1-3-19(4-2)31-24-25(35)33(21(22(26)32-24)17-6-5-7-18(27)12-17)14-20(34)30-13-15-8-10-16(11-9-15)23(28)29/h5-12,19H,3-4,13-14,27H2,1-2H3,(H3,28,29)(H,30,34)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14526 (2-[6-(3-aminophenyl)-5-chloro-3-(methylamino)-2-ox...) Show SMILES CNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C21H22ClN7O2/c1-26-20-21(31)29(17(18(22)28-20)14-3-2-4-15(23)9-14)11-16(30)27-10-12-5-7-13(8-6-12)19(24)25/h2-9H,10-11,23H2,1H3,(H3,24,25)(H,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14562 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-me...) Show SMILES Cc1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C23H25ClN6O2/c1-15-20(24)29-22(27-12-11-16-5-3-2-4-6-16)23(32)30(15)14-19(31)28-13-17-7-9-18(10-8-17)21(25)26/h2-10H,11-14H2,1H3,(H3,25,26)(H,27,29)(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14583 (2-[6-(3-aminophenyl)-5-chloro-2-oxo-3-[(2-phenylet...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2cccc(N)c2)cc1 Show InChI InChI=1S/C28H28ClN7O2/c29-25-24(21-7-4-8-22(30)15-21)36(17-23(37)34-16-19-9-11-20(12-10-19)26(31)32)28(38)27(35-25)33-14-13-18-5-2-1-3-6-18/h1-12,15H,13-14,16-17,30H2,(H3,31,32)(H,33,35)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14552 (2-[6-(3-aminophenyl)-5-chloro-3-[(3-hydroxypropyl)...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCO)c2=O)-c2cccc(N)c2)cc1 Show InChI InChI=1S/C23H26ClN7O3/c24-20-19(16-3-1-4-17(25)11-16)31(23(34)22(30-20)28-9-2-10-32)13-18(33)29-12-14-5-7-15(8-6-14)21(26)27/h1,3-8,11,32H,2,9-10,12-13,25H2,(H3,26,27)(H,28,30)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14592 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...) Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C29H30ClN7O4S/c1-42(40,41)36-23-9-5-8-22(16-23)25-26(30)35-28(33-15-14-19-6-3-2-4-7-19)29(39)37(25)18-24(38)34-17-20-10-12-21(13-11-20)27(31)32/h2-13,16,36H,14-15,17-18H2,1H3,(H3,31,32)(H,33,35)(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14533 (2-[6-(3-aminophenyl)-3-(butylamino)-5-chloro-2-oxo...) Show SMILES CCCCNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H28ClN7O2/c1-2-3-11-29-23-24(34)32(20(21(25)31-23)17-5-4-6-18(26)12-17)14-19(33)30-13-15-7-9-16(10-8-15)22(27)28/h4-10,12H,2-3,11,13-14,26H2,1H3,(H3,27,28)(H,29,31)(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14571 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H26ClFN6O2/c29-25-24(20-10-12-22(30)13-11-20)36(17-23(37)34-16-19-6-8-21(9-7-19)26(31)32)28(38)27(35-25)33-15-14-18-4-2-1-3-5-18/h1-13H,14-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14590 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...) Show SMILES CC(=O)Nc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C30H30ClN7O3/c1-19(39)36-24-9-5-8-23(16-24)26-27(31)37-29(34-15-14-20-6-3-2-4-7-20)30(41)38(26)18-25(40)35-17-21-10-12-22(13-11-21)28(32)33/h2-13,16H,14-15,17-18H2,1H3,(H3,32,33)(H,34,37)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14550 (2-[6-(3-aminophenyl)-5-chloro-3-[(2-methoxyethyl)a...) Show SMILES COCCNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C23H26ClN7O3/c1-34-10-9-28-22-23(33)31(19(20(24)30-22)16-3-2-4-17(25)11-16)13-18(32)29-12-14-5-7-15(8-6-14)21(26)27/h2-8,11H,9-10,12-13,25H2,1H3,(H3,26,27)(H,28,30)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14501 (N-[(6-carbamimidoylpyridin-3-yl)methyl]-2-{2-oxo-6...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(cnc(NCCc3ccccc3)c2=O)-c2ccccc2)cn1 Show InChI InChI=1S/C27H27N7O2/c28-25(29)22-12-11-20(15-31-22)16-32-24(35)18-34-23(21-9-5-2-6-10-21)17-33-26(27(34)36)30-14-13-19-7-3-1-4-8-19/h1-12,15,17H,13-14,16,18H2,(H3,28,29)(H,30,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14498 (CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H27ClN6O2/c29-25-24(21-9-5-2-6-10-21)35(18-23(36)33-17-20-11-13-22(14-12-20)26(30)31)28(37)27(34-25)32-16-15-19-7-3-1-4-8-19/h1-14H,15-18H2,(H3,30,31)(H,32,34)(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14520 (N-[(4-carbamimidoylphenyl)methyl]-2-(5-chloro-3-{[...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3cccc(Cl)c3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-8-4-5-18(15-22)13-14-33-27-28(38)36(24(25(30)35-27)20-6-2-1-3-7-20)17-23(37)34-16-19-9-11-21(12-10-19)26(31)32/h1-12,15H,13-14,16-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14534 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...) Show SMILES CC(C)Nc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C23H25ClN6O2/c1-14(2)28-22-23(32)30(19(20(24)29-22)16-6-4-3-5-7-16)13-18(31)27-12-15-8-10-17(11-9-15)21(25)26/h3-11,14H,12-13H2,1-2H3,(H3,25,26)(H,27,31)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14514 ((2R)-N-[(1S)-1-{[(2S)-5-carbamimidamido-1-oxo-1-(1...) Show SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1cccnc1)-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccccc1)-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-c1nccs1 |r| Show InChI InChI=1S/C33H38N8O5S2/c34-33(35)38-16-8-14-26(29(42)32-37-17-18-47-32)39-30(43)27(20-25-13-7-15-36-21-25)40-31(44)28(19-23-9-3-1-4-10-23)41-48(45,46)22-24-11-5-2-6-12-24/h1-7,9-13,15,17-18,21,26-28,41H,8,14,16,19-20,22H2,(H,39,43)(H,40,44)(H4,34,35,38)/t26-,27-,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	8.0	22
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14584 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(c...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2cccc(O)c2)cc1 Show InChI InChI=1S/C24H25ClN6O3/c25-21-20(16-3-1-6-18(32)11-16)31(24(34)23(30-21)29-17-4-2-5-17)13-19(33)28-12-14-7-9-15(10-8-14)22(26)27/h1,3,6-11,17,32H,2,4-5,12-13H2,(H3,26,27)(H,28,33)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14568 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-12-10-20(11-13-22)24-25(30)35-27(33-15-14-18-4-2-1-3-5-18)28(38)36(24)17-23(37)34-16-19-6-8-21(9-7-19)26(31)32/h1-13H,14-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14575 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(2...) Show SMILES Cc1ccccc1-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N |(5,2.09,;5,3.63,;6.34,4.4,;6.34,5.94,;5,6.71,;3.67,5.94,;3.67,4.4,;2.34,3.63,;1,4.4,;1,5.94,;-.33,3.63,;-.33,2.09,;-1.67,1.32,;-3,2.09,;-4.33,1.32,;-5.67,2.09,;-5.67,3.63,;-7,4.4,;-8.33,3.63,;-8.33,2.09,;-7,1.32,;1,1.32,;1,-.22,;2.34,2.09,;3.67,1.32,;3.67,-.22,;2.34,-.99,;5,-.99,;6.34,-.22,;7.67,-.99,;9,-.22,;10.34,-.99,;10.34,-2.53,;9,-3.3,;7.67,-2.53,;11.67,-3.3,;13.01,-2.53,;11.67,-4.84,)| Show InChI InChI=1S/C29H29ClN6O2/c1-19-7-5-6-10-23(19)25-26(30)35-28(33-16-15-20-8-3-2-4-9-20)29(38)36(25)18-24(37)34-17-21-11-13-22(14-12-21)27(31)32/h2-14H,15-18H2,1H3,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14499 (N-[(4-carbamimidoylphenyl)methyl]-2-{2-oxo-6-pheny...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(cnc(NCCc3ccccc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H28N6O2/c29-26(30)23-13-11-21(12-14-23)17-32-25(35)19-34-24(22-9-5-2-6-10-22)18-33-27(28(34)36)31-16-15-20-7-3-1-4-8-20/h1-14,18H,15-17,19H2,(H3,29,30)(H,31,33)(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14577 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(4...) Show SMILES Cc1ccc(cc1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C29H29ClN6O2/c1-19-7-11-22(12-8-19)25-26(30)35-28(33-16-15-20-5-3-2-4-6-20)29(38)36(25)18-24(37)34-17-21-9-13-23(14-10-21)27(31)32/h2-14H,15-18H2,1H3,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14585 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(c...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2ccccc2O)cc1 |(13.01,-2.53,;11.67,-3.3,;11.67,-4.84,;10.34,-2.53,;10.34,-.99,;9,-.22,;7.67,-.99,;6.34,-.22,;5,-.99,;3.67,-.22,;2.34,-.99,;3.67,1.32,;2.34,2.09,;2.34,3.63,;1,4.4,;1,5.94,;-.33,3.63,;-.33,2.09,;-1.67,1.32,;-3,2.09,;-3,3.63,;-4.54,3.63,;-4.54,2.09,;1,1.32,;1,-.22,;3.67,4.4,;3.72,5.94,;5.08,6.66,;6.39,5.85,;6.34,4.31,;4.98,3.58,;4.93,2.05,;7.67,-2.53,;9,-3.3,)| Show InChI InChI=1S/C24H25ClN6O3/c25-21-20(17-6-1-2-7-18(17)32)31(24(34)23(30-21)29-16-4-3-5-16)13-19(33)28-12-14-8-10-15(11-9-14)22(26)27/h1-2,6-11,16,32H,3-5,12-13H2,(H3,26,27)(H,28,33)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14499 (N-[(4-carbamimidoylphenyl)methyl]-2-{2-oxo-6-pheny...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(cnc(NCCc3ccccc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H28N6O2/c29-26(30)23-13-11-21(12-14-23)17-32-25(35)19-34-24(22-9-5-2-6-10-22)18-33-27(28(34)36)31-16-15-20-7-3-1-4-8-20/h1-14,18H,15-17,19H2,(H3,29,30)(H,31,33)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	8.0	22
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14587 (3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}me...) Show SMILES CC(C)Nc1nc(Cl)c(-c2cccc(c2)C(O)=O)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H25ClN6O4/c1-13(2)29-22-23(33)31(12-18(32)28-11-14-6-8-15(9-7-14)21(26)27)19(20(25)30-22)16-4-3-5-17(10-16)24(34)35/h3-10,13H,11-12H2,1-2H3,(H3,26,27)(H,28,32)(H,29,30)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14542 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(c...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NC3CCC3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C24H25ClN6O2/c25-21-20(16-5-2-1-3-6-16)31(24(33)23(30-21)29-18-7-4-8-18)14-19(32)28-13-15-9-11-17(12-10-15)22(26)27/h1-3,5-6,9-12,18H,4,7-8,13-14H2,(H3,26,27)(H,28,32)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14527 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(e...) Show SMILES CCNc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C22H23ClN6O2/c1-2-26-21-22(31)29(18(19(23)28-21)15-6-4-3-5-7-15)13-17(30)27-12-14-8-10-16(11-9-14)20(24)25/h3-11H,2,12-13H2,1H3,(H3,24,25)(H,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14529 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...) Show SMILES CCCNc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C23H25ClN6O2/c1-2-12-27-22-23(32)30(19(20(24)29-22)16-6-4-3-5-7-16)14-18(31)28-13-15-8-10-17(11-9-15)21(25)26/h3-11H,2,12-14H2,1H3,(H3,25,26)(H,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14536 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...) Show SMILES CCC(CC)Nc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C25H29ClN6O2/c1-3-19(4-2)30-24-25(34)32(21(22(26)31-24)17-8-6-5-7-9-17)15-20(33)29-14-16-10-12-18(13-11-16)23(27)28/h5-13,19H,3-4,14-15H2,1-2H3,(H3,27,28)(H,29,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14575 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(2...) Show SMILES Cc1ccccc1-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N |(5,2.09,;5,3.63,;6.34,4.4,;6.34,5.94,;5,6.71,;3.67,5.94,;3.67,4.4,;2.34,3.63,;1,4.4,;1,5.94,;-.33,3.63,;-.33,2.09,;-1.67,1.32,;-3,2.09,;-4.33,1.32,;-5.67,2.09,;-5.67,3.63,;-7,4.4,;-8.33,3.63,;-8.33,2.09,;-7,1.32,;1,1.32,;1,-.22,;2.34,2.09,;3.67,1.32,;3.67,-.22,;2.34,-.99,;5,-.99,;6.34,-.22,;7.67,-.99,;9,-.22,;10.34,-.99,;10.34,-2.53,;9,-3.3,;7.67,-2.53,;11.67,-3.3,;13.01,-2.53,;11.67,-4.84,)| Show InChI InChI=1S/C29H29ClN6O2/c1-19-7-5-6-10-23(19)25-26(30)35-28(33-16-15-20-8-3-2-4-9-20)29(38)36(25)18-24(37)34-17-21-11-13-22(14-12-21)27(31)32/h2-14H,15-18H2,1H3,(H3,31,32)(H,33,35)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14591 (N-{3-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2cccc(NC(=O)C(F)(F)F)c2)cc1 Show InChI InChI=1S/C30H27ClF3N7O3/c31-25-24(21-7-4-8-22(15-21)39-29(44)30(32,33)34)41(17-23(42)38-16-19-9-11-20(12-10-19)26(35)36)28(43)27(40-25)37-14-13-18-5-2-1-3-6-18/h1-12,15H,13-14,16-17H2,(H3,35,36)(H,37,40)(H,38,42)(H,39,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14554 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCCCCO)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C26H31ClN6O3/c27-23-22(19-8-4-3-5-9-19)33(26(36)25(32-23)30-14-6-1-2-7-15-34)17-21(35)31-16-18-10-12-20(13-11-18)24(28)29/h3-5,8-13,34H,1-2,6-7,14-17H2,(H3,28,29)(H,30,32)(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14551 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCO)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C23H25ClN6O3/c24-20-19(16-5-2-1-3-6-16)30(23(33)22(29-20)27-11-4-12-31)14-18(32)28-13-15-7-9-17(10-8-15)21(25)26/h1-3,5-10,31H,4,11-14H2,(H3,25,26)(H,27,29)(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14548 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCO)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C22H23ClN6O3/c23-19-18(15-4-2-1-3-5-15)29(22(32)21(28-19)26-10-11-30)13-17(31)27-12-14-6-8-16(9-7-14)20(24)25/h1-9,30H,10-13H2,(H3,24,25)(H,26,28)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14588 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-[3...) Show SMILES CNc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C29H30ClN7O2/c1-33-23-9-5-8-22(16-23)25-26(30)36-28(34-15-14-19-6-3-2-4-7-19)29(39)37(25)18-24(38)35-17-20-10-12-21(13-11-20)27(31)32/h2-13,16,33H,14-15,17-18H2,1H3,(H3,31,32)(H,34,36)(H,35,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14553 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-3-[(...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCCCO)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C24H27ClN6O3/c25-21-20(17-6-2-1-3-7-17)31(24(34)23(30-21)28-12-4-5-13-32)15-19(33)29-14-16-8-10-18(11-9-16)22(26)27/h1-3,6-11,32H,4-5,12-15H2,(H3,26,27)(H,28,30)(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14519 (N-[(4-carbamimidoylphenyl)methyl]-2-(5-chloro-3-{[...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccc(Cl)cc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-12-8-18(9-13-22)14-15-33-27-28(38)36(24(25(30)35-27)20-4-2-1-3-5-20)17-23(37)34-16-19-6-10-21(11-7-19)26(31)32/h1-13H,14-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14592 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...) Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C29H30ClN7O4S/c1-42(40,41)36-23-9-5-8-22(16-23)25-26(30)35-28(33-15-14-19-6-3-2-4-7-19)29(39)37(25)18-24(38)34-17-20-10-12-21(13-11-20)27(31)32/h2-13,16,36H,14-15,17-18H2,1H3,(H3,31,32)(H,33,35)(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14588 (N-[(4-carbamimidoylphenyl)methyl]-2-{5-chloro-6-[3...) Show SMILES CNc1cccc(c1)-c1c(Cl)nc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(cc1)C(N)=N Show InChI InChI=1S/C29H30ClN7O2/c1-33-23-9-5-8-22(16-23)25-26(30)36-28(34-15-14-19-6-3-2-4-7-19)29(39)37(25)18-24(38)35-17-20-10-12-21(13-11-20)27(31)32/h2-13,16,33H,14-15,17-18H2,1H3,(H3,31,32)(H,34,36)(H,35,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14498 (CHEMBL75084 | N-[(4-carbamimidoylphenyl)methyl]-2-...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C28H27ClN6O2/c29-25-24(21-9-5-2-6-10-21)35(18-23(36)33-17-20-11-13-22(14-12-20)26(30)31)28(37)27(34-25)32-16-15-19-7-3-1-4-8-19/h1-14H,15-18H2,(H3,30,31)(H,32,34)(H,33,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	8.0	22
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14557 (2-[6-(3-aminophenyl)-5-chloro-3-{[2-(dimethylamino...) Show SMILES CN(C)CCNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C24H29ClN8O2/c1-32(2)11-10-29-23-24(35)33(20(21(25)31-23)17-4-3-5-18(26)12-17)14-19(34)30-13-15-6-8-16(9-7-15)22(27)28/h3-9,12H,10-11,13-14,26H2,1-2H3,(H3,27,28)(H,29,31)(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14525 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-3-(m...) Show SMILES CNc1nc(Cl)c(-c2ccccc2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O Show InChI InChI=1S/C21H21ClN6O2/c1-25-20-21(30)28(17(18(22)27-20)14-5-3-2-4-6-14)12-16(29)26-11-13-7-9-15(10-8-13)19(23)24/h2-10H,11-12H2,1H3,(H3,23,24)(H,25,27)(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14530 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCC=C)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C23H23ClN6O2/c1-2-12-27-22-23(32)30(19(20(24)29-22)16-6-4-3-5-7-16)14-18(31)28-13-15-8-10-17(11-9-15)21(25)26/h2-11H,1,12-14H2,(H3,25,26)(H,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Coagulation factor VII (Homo sapiens (Human))	BDBM14531 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-2-ox...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCC#C)c2=O)-c2ccccc2)cc1 Show InChI InChI=1S/C23H21ClN6O2/c1-2-12-27-22-23(32)30(19(20(24)29-22)16-6-4-3-5-7-16)14-18(31)28-13-15-8-10-17(11-9-15)21(25)26/h1,3-11H,12-14H2,(H3,25,26)(H,27,29)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14567 (N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...) Show SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H26Cl2N6O2/c29-22-8-4-7-21(15-22)24-25(30)35-27(33-14-13-18-5-2-1-3-6-18)28(38)36(24)17-23(37)34-16-19-9-11-20(12-10-19)26(31)32/h1-12,15H,13-14,16-17H2,(H3,31,32)(H,33,35)(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation					Assay Description Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...				J Med Chem 46: 4050-62 (2003) Article DOI: 10.1021/jm030131l BindingDB Entry DOI: 10.7270/Q2FT8J9M
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 193 total )  |  Next  |  Last  >>

Jump to: