Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'leou' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM13534 (CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...) Show SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1 Show InChI InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase B (Homo sapiens (Human))	BDBM13534 (CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...) Show SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1 Show InChI InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora B kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase C (Homo sapiens (Human))	BDBM13534 (CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...) Show SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1 Show InChI InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora C kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM12985 (5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...) Show SMILES CO[C@@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1 |r| Show InChI InChI=1S/C26H30N6O3/c1-30-12-14-31(15-13-30)20-10-8-19(9-11-20)25(33)27-24-21-16-32(17-22(21)28-29-24)26(34)23(35-2)18-6-4-3-5-7-18/h3-11,23H,12-17H2,1-2H3,(H2,27,28,29,33)/t23-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair
Aurora kinase C (Homo sapiens (Human))	BDBM12985 (5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...) Show SMILES CO[C@@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1 |r| Show InChI InChI=1S/C26H30N6O3/c1-30-12-14-31(15-13-30)20-10-8-19(9-11-20)25(33)27-24-21-16-32(17-22(21)28-29-24)26(34)23(35-2)18-6-4-3-5-7-18/h3-11,23H,12-17H2,1-2H3,(H2,27,28,29,33)/t23-/m1/s1	PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora C kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM12985 (5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...) Show SMILES CO[C@@H](C(=O)N1Cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1)c1ccccc1 |r| Show InChI InChI=1S/C26H30N6O3/c1-30-12-14-31(15-13-30)20-10-8-19(9-11-20)25(33)27-24-21-16-32(17-22(21)28-29-24)26(34)23(35-2)18-6-4-3-5-7-18/h3-11,23H,12-17H2,1-2H3,(H2,27,28,29,33)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora B kinase				Bioorg Med Chem Lett 18: 1623-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.068 BindingDB Entry DOI: 10.7270/Q261115V
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50322822 ((S)-N-(3-(4-(2-hydroxy-1-phenylethylamino)-6-pheny...) Show SMILES OC[C@@H](Nc1ncnc2oc(c(-c3cccc(NC(=O)C=C)c3)c12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C29H24N4O3/c1-2-24(35)32-22-15-9-14-21(16-22)25-26-28(33-23(17-34)19-10-5-3-6-11-19)30-18-31-29(26)36-27(25)20-12-7-4-8-13-20/h2-16,18,23,34H,1,17H2,(H,32,35)(H,30,31,33)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged EGFR expressed in Escherichia coli				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50322823 ((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...) Show SMILES CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1 |r| Show InChI InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged EGFR expressed in Escherichia coli				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged EGFR expressed in Escherichia coli				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM13534 (CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...) Show SMILES CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1 Show InChI InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50479526 (CHEMBL515560) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2cccc(NC(C)=O)c2)cc1 Show InChI InChI=1S/C21H22N6O3/c1-13-19(21(29)24-17-6-4-5-16(11-17)23-14(2)28)20(27-25-13)26-22-12-15-7-9-18(30-3)10-8-15/h4-12H,1-3H3,(H,23,28)(H,24,29)(H2,25,26,27)/b22-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50322816 (1-{4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamin...) Show SMILES O=C(Nc1ccccc1)Nc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C33H27N5O2/c39-33(37-26-14-8-3-9-15-26)38-27-18-16-23(17-19-27)20-21-34-31-29-28(24-10-4-1-5-11-24)30(25-12-6-2-7-13-25)40-32(29)36-22-35-31/h1-19,22H,20-21H2,(H,34,35,36)(H2,37,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50322821 ((S)-N-(4-(4-(2-hydroxy-1-phenylethylamino)-6-pheny...) Show SMILES OC[C@@H](Nc1ncnc2oc(c(-c3ccc(NC(=O)C=C)cc3)c12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C29H24N4O3/c1-2-24(35)32-22-15-13-20(14-16-22)25-26-28(33-23(17-34)19-9-5-3-6-10-19)30-18-31-29(26)36-27(25)21-11-7-4-8-12-21/h2-16,18,23,34H,1,17H2,(H,32,35)(H,30,31,33)/t23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged EGFR expressed in Escherichia coli				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50322820 (CHEMBL1172781 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...) Show SMILES OC[C@@H](Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H21N3O2/c30-16-21(18-10-4-1-5-11-18)29-25-23-22(19-12-6-2-7-13-19)24(20-14-8-3-9-15-20)31-26(23)28-17-27-25/h1-15,17,21,30H,16H2,(H,27,28,29)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	223	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged EGFR expressed in Escherichia coli				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50322805 ((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-[2-(1H-imi...) Show SMILES C(Cc1cnc[nH]1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C23H19N5O/c1-3-7-16(8-4-1)19-20-22(25-12-11-18-13-24-14-26-18)27-15-28-23(20)29-21(19)17-9-5-2-6-10-17/h1-10,13-15H,11-12H2,(H,24,26)(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322817 (CHEMBL1173801 | N-{4-[2-(5,6-Diphenylfuro[2,3-d]py...) Show SMILES O=C(Nc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1)c1ccccc1 Show InChI InChI=1S/C33H26N4O2/c38-32(26-14-8-3-9-15-26)37-27-18-16-23(17-19-27)20-21-34-31-29-28(24-10-4-1-5-11-24)30(25-12-6-2-7-13-25)39-33(29)36-22-35-31/h1-19,22H,20-21H2,(H,37,38)(H,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM14800 (2-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-et...) Show SMILES OCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C20H17N3O2/c24-12-11-21-19-17-16(14-7-3-1-4-8-14)18(15-9-5-2-6-10-15)25-20(17)23-13-22-19/h1-10,13,24H,11-12H2,(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50322812 (4-(3,5-Dimethylpiperazin-1-yl)-5,6-diphenylfuro[2,...) Show SMILES CC1CN(CC(C)N1)c1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C24H24N4O/c1-16-13-28(14-17(2)27-16)23-21-20(18-9-5-3-6-10-18)22(19-11-7-4-8-12-19)29-24(21)26-15-25-23/h3-12,15-17,27H,13-14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479524 (CHEMBL474344) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2cccc(OC)c2)cc1 Show InChI InChI=1S/C20H21N5O3/c1-13-18(20(26)22-15-5-4-6-17(11-15)28-3)19(25-23-13)24-21-12-14-7-9-16(27-2)10-8-14/h4-12H,1-3H3,(H,22,26)(H2,23,24,25)/b21-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	449	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479510 (CHEMBL515112) Show SMILES COc1ccc(NC(=O)c2c(C)n[nH]c2N\N=C\c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C20H21N5O3/c1-13-18(20(26)22-15-6-10-17(28-3)11-7-15)19(25-23-13)24-21-12-14-4-8-16(27-2)9-5-14/h4-12H,1-3H3,(H,22,26)(H2,23,24,25)/b21-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322810 ((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(2-pyridin...) Show SMILES C(Cc1ccccn1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C25H20N4O/c1-3-9-18(10-4-1)21-22-24(27-16-14-20-13-7-8-15-26-20)28-17-29-25(22)30-23(21)19-11-5-2-6-12-19/h1-13,15,17H,14,16H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	535	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322813 (4-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)e...) Show SMILES Oc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C26H21N3O2/c30-21-13-11-18(12-14-21)15-16-27-25-23-22(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)31-26(23)29-17-28-25/h1-14,17,30H,15-16H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322807 (CHEMBL1173151 | [2-(4-Aminophenyl)ethyl]-(5,6-diph...) Show SMILES Nc1ccc(CCNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C26H22N4O/c27-21-13-11-18(12-14-21)15-16-28-25-23-22(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)31-26(23)30-17-29-25/h1-14,17H,15-16,27H2,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479520 (CHEMBL473334) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccc(NC(C)=O)cc2)cc1 Show InChI InChI=1S/C21H22N6O3/c1-13-19(21(29)24-17-8-6-16(7-9-17)23-14(2)28)20(27-25-13)26-22-12-15-4-10-18(30-3)11-5-15/h4-12H,1-3H3,(H,23,28)(H,24,29)(H2,25,26,27)/b22-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	719	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322809 (2-[2-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)e...) Show SMILES OCCOCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C22H21N3O3/c26-12-14-27-13-11-23-21-19-18(16-7-3-1-4-8-16)20(17-9-5-2-6-10-17)28-22(19)25-15-24-21/h1-10,15,26H,11-14H2,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322808 (CHEMBL1173152 | S-2-(5,6-Diphenylfuro[2,3-d]pyrimi...) Show SMILES C[C@@H](CO)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 |r| Show InChI InChI=1S/C21H19N3O2/c1-14(12-25)24-20-18-17(15-8-4-2-5-9-15)19(16-10-6-3-7-11-16)26-21(18)23-13-22-20/h2-11,13-14,25H,12H2,1H3,(H,22,23,24)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	792	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322806 (3-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)prop...) Show SMILES CCOC(=O)CCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C23H21N3O3/c1-2-28-18(27)13-14-24-22-20-19(16-9-5-3-6-10-16)21(17-11-7-4-8-12-17)29-23(20)26-15-25-22/h3-12,15H,2,13-14H2,1H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	796	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479527 (CHEMBL461954) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C19H19N5O2/c1-13-17(19(25)21-15-6-4-3-5-7-15)18(24-22-13)23-20-12-14-8-10-16(26-2)11-9-14/h3-12H,1-2H3,(H,21,25)(H2,22,23,24)/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	804	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322803 (1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)piperidin...) Show SMILES OC1CCN(CC1)c1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C23H21N3O2/c27-18-11-13-26(14-12-18)22-20-19(16-7-3-1-4-8-16)21(17-9-5-2-6-10-17)28-23(20)25-15-24-22/h1-10,15,18,27H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	807	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322811 ((2,5-Dimethoxy-2,5-dihydrofuran-2-ylmethyl)-(5,6-d...) Show SMILES COC1OC(CNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)(OC)C=C1 |c:34| Show InChI InChI=1S/C25H23N3O4/c1-29-19-13-14-25(30-2,32-19)15-26-23-21-20(17-9-5-3-6-10-17)22(18-11-7-4-8-12-18)31-24(21)28-16-27-23/h3-14,16,19H,15H2,1-2H3,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479521 (CHEMBL461785) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCc2cccc(OC)c2)cc1 Show InChI InChI=1S/C21H23N5O3/c1-14-19(21(27)22-12-16-5-4-6-18(11-16)29-3)20(26-24-14)25-23-13-15-7-9-17(28-2)10-8-15/h4-11,13H,12H2,1-3H3,(H,22,27)(H2,24,25,26)/b23-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	838	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322815 ((4-Aminobenzyl)-(5,6-diphenylfuro[2,3-d]pyrimidin-...) Show SMILES Nc1ccc(CNc2ncnc3oc(c(-c4ccccc4)c23)-c2ccccc2)cc1 Show InChI InChI=1S/C25H20N4O/c26-20-13-11-17(12-14-20)15-27-24-22-21(18-7-3-1-4-8-18)23(19-9-5-2-6-10-19)30-25(22)29-16-28-24/h1-14,16H,15,26H2,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	945	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479522 (CHEMBL473131) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccc(OC)c(OC)c2)cc1 Show InChI InChI=1S/C21H23N5O4/c1-13-19(21(27)23-15-7-10-17(29-3)18(11-15)30-4)20(26-24-13)25-22-12-14-5-8-16(28-2)9-6-14/h5-12H,1-4H3,(H,23,27)(H2,24,25,26)/b22-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322814 (1-(5,6-Diphenylfuro[2,3-d]pyrimidin-4-ylamino)prop...) Show SMILES C[C@@H](O)CNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 |r| Show InChI InChI=1S/C21H19N3O2/c1-14(25)12-22-20-18-17(15-8-4-2-5-9-15)19(16-10-6-3-7-11-16)26-21(18)24-13-23-20/h2-11,13-14,25H,12H2,1H3,(H,22,23,24)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	973	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479528 (CHEMBL518032) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCc2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C23H24N6O2/c1-15-21(22(29-27-15)28-26-13-16-7-9-18(31-2)10-8-16)23(30)24-12-11-17-14-25-20-6-4-3-5-19(17)20/h3-10,13-14,25H,11-12H2,1-2H3,(H,24,30)(H2,27,28,29)/b26-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479511 (CHEMBL474540) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccccc2OC)cc1 Show InChI InChI=1S/C20H21N5O3/c1-13-18(20(26)22-16-6-4-5-7-17(16)28-3)19(25-23-13)24-21-12-14-8-10-15(27-2)11-9-14/h4-12H,1-3H3,(H,22,26)(H2,23,24,25)/b21-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479517 (CHEMBL461599) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCc2ccccc2)cc1 Show InChI InChI=1S/C21H23N5O2/c1-15-19(21(27)22-13-12-16-6-4-3-5-7-16)20(26-24-15)25-23-14-17-8-10-18(28-2)11-9-17/h3-11,14H,12-13H2,1-2H3,(H,22,27)(H2,24,25,26)/b23-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479525 (CHEMBL473333) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H18FN5O2/c1-12-17(19(26)22-15-7-5-14(20)6-8-15)18(25-23-12)24-21-11-13-3-9-16(27-2)10-4-13/h3-11H,1-2H3,(H,22,26)(H2,23,24,25)/b21-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479531 (CHEMBL517573) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCc2cccnc2)cc1 Show InChI InChI=1S/C20H22N6O2/c1-14-18(20(27)22-11-9-15-4-3-10-21-12-15)19(26-24-14)25-23-13-16-5-7-17(28-2)8-6-16/h3-8,10,12-13H,9,11H2,1-2H3,(H,22,27)(H2,24,25,26)/b23-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479512 (CHEMBL516353) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)Nc2ccc(cc2)N(C)C)cc1 Show InChI InChI=1S/C21H24N6O2/c1-14-19(21(28)23-16-7-9-17(10-8-16)27(2)3)20(26-24-14)25-22-13-15-5-11-18(29-4)12-6-15/h5-13H,1-4H3,(H,23,28)(H2,24,25,26)/b22-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479529 (CHEMBL514951) Show SMILES COc1ccc(CCNC(=O)c2c(C)n[nH]c2N\N=C\c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C22H25N5O3/c1-15-20(22(28)23-13-12-16-4-8-18(29-2)9-5-16)21(27-25-15)26-24-14-17-6-10-19(30-3)11-7-17/h4-11,14H,12-13H2,1-3H3,(H,23,28)(H2,25,26,27)/b24-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479516 (CHEMBL460720) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCc2ccccc2)cc1 Show InChI InChI=1S/C20H21N5O2/c1-14-18(20(26)21-12-15-6-4-3-5-7-15)19(25-23-14)24-22-13-16-8-10-17(27-2)11-9-16/h3-11,13H,12H2,1-2H3,(H,21,26)(H2,23,24,25)/b22-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479519 (CHEMBL461784) Show SMILES COc1ccc(CNC(=O)c2c(C)n[nH]c2N\N=C\c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C21H23N5O3/c1-14-19(21(27)22-12-15-4-8-17(28-2)9-5-15)20(26-24-14)25-23-13-16-6-10-18(29-3)11-7-16/h4-11,13H,12H2,1-3H3,(H,22,27)(H2,24,25,26)/b23-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479513 (CHEMBL460905) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCc2cccc(NC(C)=O)c2)cc1 Show InChI InChI=1S/C22H24N6O3/c1-14-20(22(30)23-12-17-5-4-6-18(11-17)25-15(2)29)21(28-26-14)27-24-13-16-7-9-19(31-3)10-8-16/h4-11,13H,12H2,1-3H3,(H,23,30)(H,25,29)(H2,26,27,28)/b24-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322804 ((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(2-morphol...) Show SMILES C(CN1CCOCC1)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1 Show InChI InChI=1S/C24H24N4O2/c1-3-7-18(8-4-1)20-21-23(25-11-12-28-13-15-29-16-14-28)26-17-27-24(21)30-22(20)19-9-5-2-6-10-19/h1-10,17H,11-16H2,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479533 (CHEMBL460728) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCc2c[nH]cn2)cc1 Show InChI InChI=1S/C18H21N7O2/c1-12-16(18(26)20-8-7-14-10-19-11-21-14)17(25-23-12)24-22-9-13-3-5-15(27-2)6-4-13/h3-6,9-11H,7-8H2,1-2H3,(H,19,21)(H,20,26)(H2,23,24,25)/b22-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479518 (CHEMBL461972) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCCc2ccccc2)cc1 Show InChI InChI=1S/C22H25N5O2/c1-16-20(22(28)23-14-6-9-17-7-4-3-5-8-17)21(27-25-16)26-24-15-18-10-12-19(29-2)13-11-18/h3-5,7-8,10-13,15H,6,9,14H2,1-2H3,(H,23,28)(H2,25,26,27)/b24-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479509 (CHEMBL473948) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)NCCc2cccc(OC)c2)cc1 Show InChI InChI=1S/C22H25N5O3/c1-15-20(22(28)23-12-11-16-5-4-6-19(13-16)30-3)21(27-25-15)26-24-14-17-7-9-18(29-2)10-8-17/h4-10,13-14H,11-12H2,1-3H3,(H,23,28)(H2,25,26,27)/b24-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50322802 ((5,6-Diphenylfuro[2,3-d]pyrimidin-4-yl)-(3-imidazo...) Show SMILES C(CNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)Cn1ccnc1 Show InChI InChI=1S/C24H21N5O/c1-3-8-18(9-4-1)20-21-23(26-12-7-14-29-15-13-25-17-29)27-16-28-24(21)30-22(20)19-10-5-2-6-11-19/h1-6,8-11,13,15-17H,7,12,14H2,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4980-8 (2010) Checked by Author Article DOI: 10.1021/jm1000198 BindingDB Entry DOI: 10.7270/Q2Z60P87
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50479530 (CHEMBL517571) Show SMILES COc1ccc(\C=N\Nc2[nH]nc(C)c2C(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C20H20N4O3/c1-14-18(20(25)27-13-16-6-4-3-5-7-16)19(24-22-14)23-21-12-15-8-10-17(26-2)11-9-15/h3-12H,13H2,1-2H3,(H2,22,23,24)/b21-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3				J Med Chem 52: 1050-62 (2009) Article DOI: 10.1021/jm801270e BindingDB Entry DOI: 10.7270/Q27M0BQJ
					More data for this Ligand-Target Pair

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