Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thyroid hormone receptor beta (RAT) | BDBM50036427 (CHEMBL350265 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036401 (CHEMBL163221 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM18865 (3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036399 (Axitirome | CHEMBL159682 | N-(4-{3-[(4-Fluoro-phen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM18862 (2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | PDB PubMed | n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036402 (CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036418 (CHEMBL350049 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036423 (CHEMBL164421 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036411 (CHEMBL163324 | N-{3,5-Dichloro-4-[3-(4-chloro-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036410 (CHEMBL159976 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036424 (CHEMBL159334 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036408 (CHEMBL161828 | N-{4-[3-(4-Chloro-benzyl)-4-hydroxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036417 (CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036417 (CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.680 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036404 (CHEMBL159595 | N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036395 (CHEMBL350199 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036420 (CHEMBL161535 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036406 (CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036397 (CHEMBL348983 | N-[3,5-Dichloro-4-(4-hydroxy-3-isop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036405 (CHEMBL434476 | N-(3,5-Dichloro-4-{3-[(4-chloro-phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036398 (CHEMBL162692 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003776 (8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2) | J Med Chem 35: 4366-72 (1992) BindingDB Entry DOI: 10.7270/Q2JW8CVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036426 (CHEMBL159610 | N-{4-[3-(4-Fluoro-benzoyl)-4-hydrox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036415 (CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036414 (CHEMBL346112 | N-{4-[3-(4-Chloro-benzoyl)-4-hydrox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036430 (CHEMBL347713 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036422 (CHEMBL163020 | N-[3,5-Difluoro-4-(4-hydroxy-3-isop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003777 (8-(4-Chloro-benzenesulfonylamino)-2-(5-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2) | J Med Chem 35: 4366-72 (1992) BindingDB Entry DOI: 10.7270/Q2JW8CVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM18860 ((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036409 ((S)-2-Amino-3-[3,5-dibromo-4-(4-hydroxy-3-isopropy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036396 (CHEMBL163320 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280267 (CHEMBL295121 | [3-[3-(4-Chloro-benzenesulfonylamin...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50300929 ((S)-2-amino-3-(4-(4-amino-6-(biphenyl-2-ylmethylam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036432 (CHEMBL264041 | N-[4-(3-Isopropyl-phenoxy)-3,5-dime...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280268 (3-[3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-5-(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036403 (CHEMBL352126 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro. | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50243565 ((S)-2-amino-3-(4-(5-(naphthalen-2-ylmethylamino)py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of TPH1 (unknown origin) | J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50300932 ((S)-2-amino-3-(4-(4-amino-6-((4'-methylbiphenyl-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036412 (CHEMBL161245 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003779 (8-(4-Chloro-benzenesulfonylamino)-6-pyridin-3-ylme...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2) | J Med Chem 35: 4366-72 (1992) BindingDB Entry DOI: 10.7270/Q2JW8CVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50280264 (3-[5-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-2-(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparation | Bioorg Med Chem Lett 2: 1623-1626 (1992) Article DOI: 10.1016/S0960-894X(00)80443-6 BindingDB Entry DOI: 10.7270/Q26M36QQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor 1 (Homo sapiens (Human)) | BDBM50291519 (3-(3-Biphenyl-4-yl-but-2-enoylamino)-4-methoxy-ben...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophils | Bioorg Med Chem Lett 7: 949-954 (1997) Article DOI: 10.1016/S0960-894X(97)00134-0 BindingDB Entry DOI: 10.7270/Q25D8RW3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor 1 (Homo sapiens (Human)) | BDBM50291521 ((E)-3-Biphenyl-4-yl-N-[2-methoxy-5-(1H-tetrazol-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophils | Bioorg Med Chem Lett 7: 949-954 (1997) Article DOI: 10.1016/S0960-894X(97)00134-0 BindingDB Entry DOI: 10.7270/Q25D8RW3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50300935 ((S)-3-{4-[4-(1-Adamantan-1-yl-ethylamino)-6-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thromboxane-A synthase (Homo sapiens (Human)) | BDBM50003773 (8-(4-Chloro-benzenesulfonylamino)-5-(2-pyridin-3-y...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
CIBA-GEIGY Corporation Curated by ChEMBL | Assay Description The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2) | J Med Chem 35: 4366-72 (1992) BindingDB Entry DOI: 10.7270/Q2JW8CVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thyroid hormone receptor beta (RAT) | BDBM50036407 (CHEMBL441101 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Ciba Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptor | J Med Chem 38: 695-707 (1995) BindingDB Entry DOI: 10.7270/Q2T43TRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50243613 ((S)-2-Amino-3-(4-(4-amino-6-((naphthalene-2-ylmeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50243613 ((S)-2-Amino-3-(4-(4-amino-6-((naphthalene-2-ylmeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of TPH1 (unknown origin) | J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50243618 ((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of TPH1 (unknown origin) | J Med Chem 51: 3684-7 (2008) Article DOI: 10.1021/jm800338j BindingDB Entry DOI: 10.7270/Q2PK0FZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50300934 ((2S)-2-amino-3-(4-(4-amino-6-(1-(biphenyl-4-yl)eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair |
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