Compile Data Set for Download or QSAR

Found 3464 hits with Last Name = 'ogawa' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM35667 (AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...) Show SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O Show InChI InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...) Show SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O Show InChI InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35667 (AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...) Show SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O Show InChI InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM35667 (AVP | CHEMBL373742 | US10131692, 44 (AVP) | [3H]Ar...) Show SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O Show InChI InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	6.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	9.42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	12.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Homo sapiens (Human))	BDBM50386618 (CHEMBL2048443) Show SMILES O[C@H]1C[C@@H](O[C@@H]1COP(O)(=O)CP(O)(=O)OP(O)(=O)OCc1ccccc1)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C17H23N2O13P3/c20-13-8-16(19-7-6-15(21)18-17(19)22)31-14(13)10-29-33(23,24)11-34(25,26)32-35(27,28)30-9-12-4-2-1-3-5-12/h1-7,13-14,16,20H,8-11H2,(H,23,24)(H,25,26)(H,27,28)(H,18,21,22)/t13-,14+,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human dUTPase				J Med Chem 55: 2960-9 (2012) Article DOI: 10.1021/jm201627n BindingDB Entry DOI: 10.7270/Q2WQ04VS
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (RAT)	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	524	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1A4 (Rattus norvegicus)	BDBM18957 ((2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-di...) Show SMILES CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1 Show InChI InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku University School of Medicine Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Digoxin uptake in Xenopus laevis oocytes				Endocrinology 142: 2005-12 (2001) Article DOI: 10.1210/endo.142.5.8115 BindingDB Entry DOI: 10.7270/Q2GF0XB3
					More data for this Ligand-Target Pair
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM35714 (CHEMBL420762 | Mozavaptan | N-[4-(5-Dimethylamino-...) Show SMILES CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc12 Show InChI InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM35723 (CHEMBL344159 | N-[4-(7-Chloro-5-hydroxy-2,3,4,5-te...) Show SMILES Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3cc(Cl)ccc23)c(C)c1 Show InChI InChI=1S/C26H25ClN2O3/c1-16-6-3-4-7-20(16)25(31)28-19-10-11-21(17(2)14-19)26(32)29-13-5-8-24(30)22-15-18(27)9-12-23(22)29/h3-4,6-7,9-12,14-15,24,30H,5,8,13H2,1-2H3,(H,28,31)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP Ki Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Homo sapiens (Human))	BDBM50173539 (1-(4-Hydroxy-5-trityloxymethyl-tetrahydro-furan-2-...) Show SMILES O[C@H]1C[C@@H](O[C@@H]1COC(c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C28H26N2O5/c31-23-18-26(30-17-16-25(32)29-27(30)33)35-24(23)19-34-28(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-17,23-24,26,31H,18-19H2,(H,29,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysis				J Med Chem 55: 2970-80 (2012) Article DOI: 10.1021/jm201628y BindingDB Entry DOI: 10.7270/Q2C82BB5
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456491 (US10723742, Example 218 | US10723742, Example 221 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31ClF2N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(29(35)28(30)33)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(34)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456476 (US10723742, Example 202 | US11510915, Example 202) Show SMILES Cc1noc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:34:33:31.30:28| Show InChI InChI=1S/C28H22F2N4O2/c1-14-20-11-24(30)22(12-27(20)36-33-14)19-6-4-16(28(35)34-18-5-7-26(34)25(32)10-18)8-21(19)15-2-3-17(13-31)23(29)9-15/h2-4,6,8-9,11-12,18,25-26H,5,7,10,32H2,1H3/t18-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456492 (US10723742, Example 219 | US11510915, Example 219) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C30H29ClF2N6O2/c1-3-30(41,4-2)16-39-28-25(36-37-39)13-23(27(33)26(28)31)21-8-7-18(29(40)38-10-9-20(35)15-38)11-22(21)17-5-6-19(14-34)24(32)12-17/h5-8,11-13,20,41H,3-4,9-10,15-16,35H2,1-2H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456487 (US10723742, Example 214 | US10723742, Example 217 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31F3N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(28(34)29(30)35)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(33)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456471 (US10723742, Example 197 | US11510915, Example 197) Show SMILES CC(C)(O)Cn1ncc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C30H28F3N5O2/c1-29(2,40)15-38-27-20(14-36-38)11-23(25(32)26(27)33)21-7-6-18(28(39)37-9-8-30(3,35)16-37)10-22(21)17-4-5-19(13-34)24(31)12-17/h4-7,10-12,14,40H,8-9,15-16,35H2,1-3H3/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456500 (US10723742, Example 228 | US10723742, Example 241 ...) Show SMILES Cc1c(F)c(cc2nnn(CC(C)(C)O)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C31H30F2N6O2/c1-16-28(33)23(13-26-29(16)38(37-36-26)15-31(2,3)41)21-8-6-18(30(40)39-20-7-9-27(39)25(35)12-20)10-22(21)17-4-5-19(14-34)24(32)11-17/h4-6,8,10-11,13,20,25,27,41H,7,9,12,15,35H2,1-3H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456493 (US10723742, Example 220 | US11510915, Example 220) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:42:41:37.38:35| Show InChI InChI=1S/C33H33ClF2N6O2/c1-3-33(44,4-2)17-41-31-28(39-40-41)15-26(30(36)29(31)34)24-10-7-19(11-25(24)18-5-6-20(16-37)27(35)12-18)32(43)42-22-8-9-23(42)14-21(38)13-22/h5-7,10-12,15,21-23,44H,3-4,8-9,13-14,17,38H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456528 (US10723742, Example 257 | US10723742, Example 269 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 |THB:0:1:5.4:7| Show InChI InChI=1S/C31H27ClF2N6O2/c32-27-28(34)22(13-25-29(27)39(38-37-25)15-31(42)8-1-9-31)20-6-4-17(30(41)40-19-5-7-26(40)24(36)12-19)10-21(20)16-2-3-18(14-35)23(33)11-16/h2-4,6,10-11,13,19,24,26,42H,1,5,7-9,12,15,36H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456304 (US10723742, Example 123 | US10723742, Example 23 |...) Show SMILES Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:35:34:30.31:28| Show InChI InChI=1S/C30H26F2N4O/c1-35-9-8-18-10-26(28(32)15-29(18)35)24-7-4-19(11-25(24)17-2-3-20(16-33)27(31)12-17)30(37)36-22-5-6-23(36)14-21(34)13-22/h2-4,7-12,15,21-23H,5-6,13-14,34H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456529 (US10723742, Example 258 | US11510915, Example 258) Show SMILES N[C@H]1CCN(C1)C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(Cl)c2F)c(c1)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C29H25ClF2N6O2/c30-25-26(32)22(12-24-27(25)38(36-35-24)15-29(40)7-1-8-29)20-5-4-17(28(39)37-9-6-19(34)14-37)10-21(20)16-2-3-18(13-33)23(31)11-16/h2-5,10-12,19,40H,1,6-9,14-15,34H2/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456525 (US10723742, Example 254 | US10723742, Example 268 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(-c2cc3nnn(CC4(O)CCC4)c3c(F)c2F)c(c1)-c1ccc(C#N)c(F)c1 |THB:0:1:5.4:7| Show InChI InChI=1S/C31H27F3N6O2/c32-23-11-16(2-3-18(23)14-35)21-10-17(30(41)40-19-5-7-26(40)24(36)12-19)4-6-20(21)22-13-25-29(28(34)27(22)33)39(38-37-25)15-31(42)8-1-9-31/h2-4,6,10-11,13,19,24,26,42H,1,5,7-9,12,15,36H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456485 (US10723742, Example 211 | US11510915, Example 211) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:40:39:35.36:33| Show InChI InChI=1S/C31H29ClF2N6O2/c1-31(2,42)15-39-29-26(37-38-39)13-24(28(34)27(29)32)22-8-5-17(9-23(22)16-3-4-18(14-35)25(33)10-16)30(41)40-20-6-7-21(40)12-19(36)11-20/h3-5,8-10,13,19-21,42H,6-7,11-12,15,36H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456530 (US10723742, Example 259 | US10723742, Example 272 ...) Show SMILES Cc1c(F)c(cc2nnn(CC3(O)CCC3)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:41:40:36.37:34| Show InChI InChI=1S/C33H32F2N6O2/c1-18-30(35)27(15-29-31(18)40(39-38-29)17-33(43)9-2-10-33)25-8-5-20(11-26(25)19-3-4-21(16-36)28(34)12-19)32(42)41-23-6-7-24(41)14-22(37)13-23/h3-5,8,11-12,15,22-24,43H,2,6-7,9-10,13-14,17,37H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456470 (US10723742, Example 196 | US11510915, Example 196) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C32H29F3N4O2/c1-32(2,41)16-38-10-9-18-11-24(28(34)29(35)30(18)38)22-7-5-19(31(40)39-21-6-8-27(39)26(37)14-21)12-23(22)17-3-4-20(15-36)25(33)13-17/h3-5,7,9-13,21,26-27,41H,6,8,14,16,37H2,1-2H3/t21-,26+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456449 (US10723742, Example 175 | US10723742, Example 185 ...) Show SMILES Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:35:34:32.31:29| Show InChI InChI=1S/C27H21F3N6O/c1-35-26-22(33-34-35)11-19(24(29)25(26)30)17-6-4-14(27(37)36-16-5-7-23(36)21(32)10-16)8-18(17)13-2-3-15(12-31)20(28)9-13/h2-4,6,8-9,11,16,21,23H,5,7,10,32H2,1H3/t16-,21+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456531 (US10723742, Example 260 | US10723742, Example 263 ...) Show SMILES N[C@H]1C[C@H]2CC[C@@H]1N2C(=O)c1ccc(c(c1)-c1ccc(C#N)c(F)c1)-c1cc2nnn(CC3(O)CCC3)c2c(C(F)F)c1F |THB:0:1:5.4:7| Show InChI InChI=1S/C32H28F4N6O2/c33-23-11-16(2-3-18(23)14-37)21-10-17(31(43)42-19-5-7-26(42)24(38)12-19)4-6-20(21)22-13-25-29(27(28(22)34)30(35)36)41(40-39-25)15-32(44)8-1-9-32/h2-4,6,10-11,13,19,24,26,30,44H,1,5,7-9,12,15,38H2/t19-,24+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456541 (US10723742, Example 270 | US10723742, Example 276 ...) Show SMILES Cc1c(F)c(cc2nnn(CC3(O)CCC3)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:40:39:37.36:34| Show InChI InChI=1S/C32H30F2N6O2/c1-17-29(34)24(14-27-30(17)39(38-37-27)16-32(42)9-2-10-32)22-7-5-19(31(41)40-21-6-8-28(40)26(36)13-21)11-23(22)18-3-4-20(15-35)25(33)12-18/h3-5,7,11-12,14,21,26,28,42H,2,6,8-10,13,16,36H2,1H3/t21-,26+,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456483 (US10723742, Example 209 | US10723742, Example 213 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27ClF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456464 (US10723742, Example 190 | US11510915, Example 190) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C31H30F2N4O2/c1-30(2,39)17-36-10-8-20-12-25(27(33)15-28(20)36)23-7-6-21(29(38)37-11-9-31(3,35)18-37)13-24(23)19-4-5-22(16-34)26(32)14-19/h4-8,10,12-15,39H,9,11,17-18,35H2,1-3H3/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456484 (US10723742, Example 210 | US11510915, Example 210) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 Show InChI InChI=1S/C28H25ClF2N6O2/c1-28(2,39)14-37-26-23(34-35-37)11-21(25(31)24(26)29)19-6-5-16(27(38)36-8-7-18(33)13-36)9-20(19)15-3-4-17(12-32)22(30)10-15/h3-6,9-11,18,39H,7-8,13-14,33H2,1-2H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456517 (US10723742, Example 246 | US10723742, Example 252 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(C(F)F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C31H28F4N6O2/c1-31(2,43)14-40-28-24(38-39-40)12-21(27(33)26(28)29(34)35)19-7-5-16(30(42)41-18-6-8-25(41)23(37)11-18)9-20(19)15-3-4-17(13-36)22(32)10-15/h3-5,7,9-10,12,18,23,25,29,43H,6,8,11,14,37H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50264847 (CHEMBL4096902) Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(cn2)C#N)n1 Show InChI InChI=1S/C25H23N9OS2/c1-14-22(37-15(2)30-14)20-13-36-25(31-20)32-21-6-3-17(10-27-21)23(35)34-18-4-5-19(34)12-33(11-18)24-28-8-16(7-26)9-29-24/h3,6,8-10,13,18-19H,4-5,11-12H2,1-2H3,(H,27,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...				Bioorg Med Chem 25: 2177-2190 (2017) Article DOI: 10.1016/j.bmc.2017.02.047 BindingDB Entry DOI: 10.7270/Q2N58PT9
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456472 (US10723742, Example 198 | US11510915, Example 198) Show SMILES CC(C)(O)Cn1ccc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@](C)(N)C1 Show InChI InChI=1S/C31H29F3N4O2/c1-30(2,40)16-37-10-8-19-12-24(26(33)27(34)28(19)37)22-7-6-20(29(39)38-11-9-31(3,36)17-38)13-23(22)18-4-5-21(15-35)25(32)14-18/h4-8,10,12-14,40H,9,11,16-17,36H2,1-3H3/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456304 (US10723742, Example 123 | US10723742, Example 23 |...) Show SMILES Cn1ccc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2 |THB:35:34:30.31:28| Show InChI InChI=1S/C30H26F2N4O/c1-35-9-8-18-10-26(28(32)15-29(18)35)24-7-4-19(11-25(24)17-2-3-20(16-33)27(31)12-17)30(37)36-22-5-6-23(36)14-21(34)13-22/h2-4,7-12,15,21-23H,5-6,13-14,34H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456544 (US10723742, Example 273 | US10723742, Example 277 ...) Show SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C30H27BrF2N6O2/c1-30(2,41)14-38-28-24(36-37-38)12-21(27(33)26(28)31)19-7-5-16(29(40)39-18-6-8-25(39)23(35)11-18)9-20(19)15-3-4-17(13-34)22(32)10-15/h3-5,7,9-10,12,18,23,25,41H,6,8,11,14,35H2,1-2H3/t18-,23+,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50256209 (CHEMBL4101768) Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3COCC2CN(C3)c2ncc(cn2)C(F)(F)F)n1 Show InChI InChI=1S/C25H23F3N8O2S2/c1-13-21(40-14(2)32-13)19-12-39-24(33-19)34-20-4-3-15(5-29-20)22(37)36-17-8-35(9-18(36)11-38-10-17)23-30-6-16(7-31-23)25(26,27)28/h3-7,12,17-18H,8-11H2,1-2H3,(H,29,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...				Bioorg Med Chem 25: 2177-2190 (2017) Article DOI: 10.1016/j.bmc.2017.02.047 BindingDB Entry DOI: 10.7270/Q2N58PT9
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456491 (US10723742, Example 218 | US10723742, Example 221 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(Cl)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31ClF2N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(29(35)28(30)33)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(34)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456469 (US10723742, Example 195 | US11510915, Example 195) Show SMILES CC(C)(O)Cn1ncc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C31H28F3N5O2/c1-31(2,41)15-38-29-19(14-37-38)10-23(27(33)28(29)34)21-7-5-17(30(40)39-20-6-8-26(39)25(36)12-20)9-22(21)16-3-4-18(13-35)24(32)11-16/h3-5,7,9-11,14,20,25-26,41H,6,8,12,15,36H2,1-2H3/t20-,25+,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456508 (US10723742, Example 237 | US10723742, Example 243 ...) Show SMILES CNC(=O)Cc1cn(C)c2cc(F)c(cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:39:38:36.35:33| Show InChI InChI=1S/C32H29F2N5O2/c1-37-31(40)11-20-16-38(2)30-14-27(34)25(13-24(20)30)22-7-5-18(32(41)39-21-6-8-29(39)28(36)12-21)9-23(22)17-3-4-19(15-35)26(33)10-17/h3-5,7,9-10,13-14,16,21,28-29H,6,8,11-12,36H2,1-2H3,(H,37,40)/t21-,28+,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456480 (US10723742, Example 206 | US10723742, Example 225 ...) Show SMILES CCC(O)(CC)Cn1ncc2cc(c(F)cc12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:40:39:37.36:34| Show InChI InChI=1S/C33H33F2N5O2/c1-3-33(42,4-2)18-39-31-15-28(35)26(12-22(31)17-38-39)24-9-7-20(32(41)40-23-8-10-30(40)29(37)14-23)11-25(24)19-5-6-21(16-36)27(34)13-19/h5-7,9,11-13,15,17,23,29-30,42H,3-4,8,10,14,18,37H2,1-2H3/t23-,29+,30+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50264846 (CHEMBL4066531) Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccc(cn2)C(=O)N2C3CCC2CN(C3)c2ncc(Br)cn2)n1 Show InChI InChI=1S/C24H23BrN8OS2/c1-13-21(36-14(2)29-13)19-12-35-24(30-19)31-20-6-3-15(7-26-20)22(34)33-17-4-5-18(33)11-32(10-17)23-27-8-16(25)9-28-23/h3,6-9,12,17-18H,4-5,10-11H2,1-2H3,(H,26,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd Curated by ChEMBL					Assay Description Antagonist activity at recombinant human TRPV4 expressed in CHOK1 cells assessed as inhibition of 4alphaPDD-induced activation pretreated for 5 mins ...				Bioorg Med Chem 25: 2177-2190 (2017) Article DOI: 10.1016/j.bmc.2017.02.047 BindingDB Entry DOI: 10.7270/Q2N58PT9
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM456487 (US10723742, Example 214 | US10723742, Example 217 ...) Show SMILES CCC(O)(CC)Cn1nnc2cc(c(F)c(F)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2 |TLB:41:40:38.37:35| Show InChI InChI=1S/C32H31F3N6O2/c1-3-32(43,4-2)16-40-30-26(38-39-40)14-23(28(34)29(30)35)21-9-7-18(31(42)41-20-8-10-27(41)25(37)13-20)11-22(21)17-5-6-19(15-36)24(33)12-17/h5-7,9,11-12,14,20,25,27,43H,3-4,8,10,13,16,37H2,1-2H3/t20-,25+,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...				US Patent US10723742 (2020) BindingDB Entry DOI: 10.7270/Q2TF01DB
					More data for this Ligand-Target Pair

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