Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human)) | BDBM50156495 (8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
School of Natural Sciences--Chemistry Curated by ChEMBL | Assay Description Inhibitory activity against DNA-dependent protein kinase receptor | J Med Chem 48: 7829-46 (2005) Article DOI: 10.1021/jm050444b BindingDB Entry DOI: 10.7270/Q2Z31Z60 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091449 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-methanesulf...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human)) | BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University Curated by ChEMBL | Assay Description Binding affinity for DNA dependent protein kinase isolated from HeLa cells; Range is 20-120 | J Med Chem 48: 569-85 (2005) Article DOI: 10.1021/jm049526a BindingDB Entry DOI: 10.7270/Q2BK1BV9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM15234 ((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University Curated by ChEMBL | Assay Description Inhibition of human recombinant p110 alpha Phosphatidylinositol 3-kinase | J Med Chem 48: 569-85 (2005) Article DOI: 10.1021/jm049526a BindingDB Entry DOI: 10.7270/Q2BK1BV9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091457 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-2-m...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 234 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091454 ((E)-3-(4-Bromo-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091461 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(4-hydroxy-1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091451 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(6-hydroxy-1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091458 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091465 ((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091445 ((E)-3-(4-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091471 ((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091460 ((E)-3-(3-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091470 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-methoxy-1H-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091442 ((E)-3-(3,4-Dichloro-phenyl)-N-{4-[4-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091467 ((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091448 ((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091439 ((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)c...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091468 ((E)-3-(4-Dimethylamino-phenyl)-N-{5-[4-(1H-indol-3...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091443 ((E)-3-Biphenyl-4-yl-N-{5-[4-(1H-indol-3-yl)-piperi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091441 (1-(3,4-Dichloro-phenyl)-3-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091447 ((E)-3-(4-tert-Butyl-phenyl)-N-{5-[4-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091453 ((E)-3-(3,4-Dichloro-phenyl)-N-{3-[4-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091446 ((E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091452 ((E)-3-(4-Acetylamino-phenyl)-N-{5-[4-(1H-indol-3-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091456 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1-m...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 5 (Homo sapiens (Human)) | BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091466 ((E)-3-(2-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091464 (2-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091459 (3,4-Dichloro-N-{5-[4-(1H-indol-3-yl)-piperidin-1-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091444 (Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091444 (Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091450 (3-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University Curated by ChEMBL | Assay Description Binding affinity for Phosphatidylinositol-3-kinase isolated from HeLa cells; Range is 20-120 | J Med Chem 48: 569-85 (2005) Article DOI: 10.1021/jm049526a BindingDB Entry DOI: 10.7270/Q2BK1BV9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091455 ((E)-3-(4-Hydroxy-phenyl)-N-{5-[4-(1H-indol-3-yl)-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091472 (4-Bromo-N-{5-[4-(1H-indol-3-yl)-piperidin-1-yl]-pe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091463 (3,4-Dichloro-N-{5-[4-(1H-indol-3-yl)-piperidin-1-y...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091469 (Biphenyl-4-carboxylic acid {6-[4-(1H-indol-3-yl)-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 2 (Homo sapiens (Human)) | BDBM50091462 ((E)-3-(3,4-Dichloro-phenyl)-N-{2-[4-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Antagonist activity against C-C chemokine receptor type 2 | Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513567 ((R)-3-(5-(2′-methoxy-[1,1′-biphenyl]-3...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513564 (3-(5-(4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]o...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513570 ((R)-3-(5-([1,1'-biphenyl]-3-yl)-1,1- dioxido-1,2,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513572 ((R)-3-(5-(4-methoxy-[1,1'- biphenyl]-3-yl)-1,1-dio...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513574 ((R)-3-(5-(3'-methoxy-[1,1'- biphenyl]-3-yl)-1,1-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513575 ((R)-3-(5-(2'-methoxy-[1,1'- biphenyl]-4-yl)-1,1-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513576 ((R)-3-(1,1-dioxido-5-(4-(pyridin-4- yl)phenyl)-1,2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513577 ((R)-3-(1,1-dioxido-5-(3-(pyridin-4- yl)phenyl)-1,2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513578 ((R)-3-(5-(3-(1-methyl-1H-pyrazol- 4-yl)phenyl)-1,1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ubiquitin carboxyl-terminal hydrolase 30 (Homo sapiens (Human)) | BDBM513568 ((R)-3-(5-([1,1'-biphenyl]-4-yl)-1,1- dioxido-1,2,5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po... | Citation and Details BindingDB Entry DOI: 10.7270/Q200056C | |||||||||||
More data for this Ligand-Target Pair |
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