Found 344 hits Enz. Inhib. hit(s) with Target = 'Presequence protease, mitochondrial' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622271
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)Show SMILES Cc1ccc2c(ccnc2c1)C(=O)NCC(=O)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622271
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-7-m...)Show SMILES Cc1ccc2c(ccnc2c1)C(=O)NCC(=O)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622272
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)Show SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622272
((R)-N-(2-(4-cyanothiazolidin-3-yl)-2-oxoethyl)-qui...)Show SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514515
(US11096924, DASH-inhibitors 3102 C | US11583516, C...)Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(Cl)(C3)C1)C2 |r,TLB:1:12:20:16.15.17,22:12:20:16.15.17,15:16:21:20.14.13,THB:22:16:20:21.12.13,15:14:21:16.22.17| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514521
(US11096924, DASH-inhibitors 4268 | US11583516, Cmp...) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622160
(US20230312550, Example 120)Show SMILES Fc1ccc2n(ccc2c1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622099
(US20230312550, Example 59)Show SMILES F[C@@H]1CCCCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514516
(US11096924, DASH-inhibitors 4175 CH | US11583516, ...)Show SMILES CC1(CCCCC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622227
(US20230312550, Example 187)Show SMILES Clc1ccc(CC2CN(C2)c2ccc3nccc(C(=O)NCC(=O)N4CSC[C@H]4C#N)c3c2)cc1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514514
(US11096924, DASH-inhibitors (formerly 3102 A 2C) |...)Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(C3)C1)C2 |r,TLB:19:18:21:15.14.13,19:14:21:18.20.17,THB:1:12:15:18.19.17,20:18:15:21.12.13,20:12:15:18.19.17| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514532
(US11096924, DASH-inhibitors 3102 A | US11583516, C...)Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C12CC3CC(CC(O)(C3)C1)C2 |r,TLB:1:12:20:16.15.17,22:12:20:16.15.17,15:16:21:20.14.13,THB:22:16:20:21.12.13,15:14:21:16.22.17| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514530
(US11096924, DASH-inhibitors 4949 | US11583516, Cmp...)Show SMILES N[C@H](C(=O)N1CCC[C@H]1B(O)O)C1(CC1)C(F)(F)F |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514520
(US11096924, DASH-inhibitors 4175 CP | US11583516, ...)Show SMILES CC1(CCCC1)[C@H](N)C(=O)N1CCC[C@H]1B(O)O |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622159
(US20230312550, Example 119)Show SMILES Fc1cc(F)c2ccn(-c3ccc4nccc(C(=O)NCC(=O)N5CSC[C@H]5C#N)c4c3)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622236
(US20230312550, Example 196)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-c1ccn[nH]1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622100
(US20230312550, Example 60)Show SMILES F[C@H]1CCCCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622263
(US20230312550, Example 223)Show SMILES FC1(CCN(CC1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1)c1ccccc1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622214
(US20230312550, Example 174)Show SMILES Cn1nccc1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622161
(US20230312550, Example 121)Show SMILES Cc1ccn(c1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622061
(US20230312550, Example 21)Show SMILES FC1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622105
(US20230312550, Example 65)Show SMILES C[C@H]1CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622168
(US20230312550, Example 128)Show SMILES Cc1ncccc1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622086
(US20230312550, Example 46)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCCC2(CC2)C1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622251
(US20230312550, Example 211)Show SMILES C[C@@H]1CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622165
(US20230312550, Example 125)Show SMILES Fc1ccc(nc1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622218
(US20230312550, Example 178)Show SMILES COc1ccc(cn1)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622240
(US20230312550, Example 200)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC[C@H]1C1CC1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622155
(US20230312550, Example 115)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-n1cc2CCCCc2n1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622167
(US20230312550, Example 127)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)-c1cncnc1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622091
(US20230312550, Example 51)Show SMILES F[C@H]1CCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622225
(US20230312550, Example 185)Show SMILES Fc1ccc(cc1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622223
(US20230312550, Example 183)Show SMILES Cc1ccc(cc1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622051
(US20230312550, Example 11)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCCC1=O)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622226
(US20230312550, Example 186)Show SMILES Cc1cccc(c1)C1CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622097
(US20230312550, Example 57)Show SMILES CC1(C)CCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
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Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622059
(US20230312550, Example 19)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC11CCC1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622057
(US20230312550, Example 17)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CC2(CCC2)C1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622063
(US20230312550, Example 23)Show SMILES FC1(F)CN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622239
(US20230312550, Example 199)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCC[C@@H]1C1CC1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622157
(US20230312550, Example 117)Show SMILES CC1(C)CCc2cn(nc12)-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622088
(US20230312550, Example 48)Show SMILES CC1(C)CCN(C1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622140
(US20230312550, Example 100)Show SMILES C[C@H]1COC[C@@H](C)N1c1cc2c(ccnc2cc1Br)C(=O)NCC(=O)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622093
(US20230312550, Example 53)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CC2CCCC2C1)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622098
(US20230312550, Example 58)Show SMILES FC[C@H]1CC2(CC2)CN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622085
(US20230312550, Example 45)Show SMILES FC[C@@H]1CCCCN1c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622256
(US20230312550, Example 216)Show SMILES Cc1noc(C)c1-c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622046
(US20230312550, Example 6)Show SMILES O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCOc2ccccc12)N1CSC[C@H]1C#N |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial
(Homo sapiens (Human)) | BDBM622232
(US20230312550, Example 192)Show SMILES CC(C)C1(O)CCN(CC1)c1ccc2nccc(C(=O)NCC(=O)N3CSC[C@H]3C#N)c2c1 |r| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Presequence protease, mitochondrial (PREP)
(Homo sapiens (Human)) | BDBM514555
(US11096924, DASH-inhibitors 4367 | US11583516, Cmp...) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Materials: Enzymes Recombinant human DPPIV (R&D Systems, Cat. No. 1180-SE). Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527). Recombin... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27P93BT |
More data for this Ligand-Target Pair | |