Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM86068 (PPC) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139137 (CHEMBL3759162) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50594668 (CHEMBL5174712) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113921 BindingDB Entry DOI: 10.7270/Q2VT1X23 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144692 (CHEMBL3759251) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50454598 (CHEMBL4215208) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Davis Curated by ChEMBL | Assay Description Inhibition of PON1 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assay | Bioorg Med Chem Lett 28: 762-768 (2018) Article DOI: 10.1016/j.bmcl.2018.01.003 BindingDB Entry DOI: 10.7270/Q2PV6NZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM158481 (US9029401, 1728 (t-TUCB)) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Davis Curated by ChEMBL | Assay Description Inhibition of PON1 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assay | Bioorg Med Chem Lett 28: 762-768 (2018) Article DOI: 10.1016/j.bmcl.2018.01.003 BindingDB Entry DOI: 10.7270/Q2PV6NZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50454599 (CHEMBL4216368) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Davis Curated by ChEMBL | Assay Description Inhibition of PON1 (unknown origin) expressed in baculovirus system using CMNA substrate by fluorescence based assay | Bioorg Med Chem Lett 28: 762-768 (2018) Article DOI: 10.1016/j.bmcl.2018.01.003 BindingDB Entry DOI: 10.7270/Q2PV6NZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144693 (CHEMBL3758983) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139133 (CHEMBL3759178) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139135 (CHEMBL3759775) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144739 (CHEMBL3759516) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139132 (CHEMBL1462074) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139134 (CHEMBL3758686) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50001839 (CHEMBL428647 | PACLITAXEL | taxol) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.65E+4 | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243044 ((2-Bromo-4,5-dimethoxyphenyl)(2,3-dibromo-5,6-dime...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243045 ((3-Bromo-4,5-dimethoxyphenyl)(2,3-dibromo-5,6-dime...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM92331 (Lornoxicam) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 9.00E+3 | -6.88 | 1.36E+5 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243043 ((2,3-dibromo-5,6-dimethoxyphenyl)(3,4-dimethoxyphe...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.74E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50316126 (Bleph-10 | Bleph-30 | Blephamide | CHEMBL455 | Cet...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents | Article PubMed | 8.60E+4 | n/a | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM10860 (4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 |...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+5 | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.70E+4 | -5.47 | 1.95E+5 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50127140 ((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.31E+5 | n/a | 2.26E+5 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144690 (CHEMBL3759001) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.38E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM82185 (Sulfosalazine, 3) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.70E+5 | n/a | 2.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50139136 (CHEMBL3759337) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM92332 (Tenoxicam) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 3.06E+5 | -4.79 | 3.40E+5 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM25902 (4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 7.02E+5 | n/a | 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144740 (CHEMBL3758357) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144738 (CHEMBL3758838) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144691 (CHEMBL3759697) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.27E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM36351 (CID148124 | Docetaxel) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 2.91E+5 | n/a | 6.65E+5 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243048 ((3-Bromo-4,5-dihydroxyphenyl)(2,3-dibromo-5,6-dihy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.43E+5 | n/a | 8.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243046 ((2,3-Dibromo-5,6-dihydroxyphenyl)(3,4-dihydroxyphe...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.32E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243047 ((2-Bromo-4,5-dihydroxyphenyl)(2,3-dibromo-5,6-dihy...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.11E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM243042 ((2,3-dimethoxyphenyl)(3,4-dimethoxyphenyl)methanon...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.21E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412 nm. Paraoxonase activity was determined spectrophotometrically using the same pr... | J Enzyme Inhib Med Chem 28: 1073-9 (2013) Article DOI: 10.3109/14756366.2012.715287 BindingDB Entry DOI: 10.7270/Q29W0DDQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM10868 (1,3,4-Thiadiazole-2-sulfonamide, 6 | 1,3,4-thiadia...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | 2.00E+6 | n/a | 1.24E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Atatürk University | Assay Description The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi... | Chem Biol Drug Des 76: 552-8 (2010) Article DOI: 10.1111/j.1747-0285.2010.01036.x BindingDB Entry DOI: 10.7270/Q2Q52N3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50127646 (CHEMBL42577 | Phosphoric acid 4-amino-phenyl ester...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.28E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description Inhibitory activity against human serum paraoxonase (PON1) | Bioorg Med Chem Lett 13: 1623-6 (2003) BindingDB Entry DOI: 10.7270/Q23B60P7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50174201 (ARTHROTEC | GP 45840 | SOLARAZE | Sodium; [2-(2,6-...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 8.05E+5 | -4.22 | 1.64E+6 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144742 (CHEMBL3758332) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.06E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM14675 (CHEMBL26128 | Fragment 5 | Phenylphosphate | pheno...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 3.25E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description Inhibitory activity against human serum paraoxonase (PON1) | Bioorg Med Chem Lett 13: 1623-6 (2003) BindingDB Entry DOI: 10.7270/Q23B60P7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50127647 (CHEMBL296745 | Phosphoric acid diethyl ester pheny...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 3.27E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description Inhibitory activity against human serum paraoxonase (PON1) | Bioorg Med Chem Lett 13: 1623-6 (2003) BindingDB Entry DOI: 10.7270/Q23B60P7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50144741 (CHEMBL3760112) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.33E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
In£n£ University Curated by ChEMBL | Assay Description Inhibition of human serum PON1 using paraoxon as substrate by spectrophotometric analysis | Bioorg Med Chem 24: 1392-401 (2016) Article DOI: 10.1016/j.bmc.2016.02.012 BindingDB Entry DOI: 10.7270/Q2FT8NWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM50022271 (2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.30E+7 | -2.57 | 6.23E+6 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM92333 (Lincomycine) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 1.11E+7 | -2.66 | 1.30E+7 | n/a | n/a | n/a | n/a | 10.5 | 25 |
Atatürk University | Assay Description The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy... | J Enzyme Inhib Med Chem 24: 1034-9 (2009) Article DOI: 10.1080/14756360802608351 BindingDB Entry DOI: 10.7270/Q2TT4PKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM24514 (4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.85E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Birmingham Curated by ChEMBL | Assay Description Inhibitory activity against human serum paraoxonase (PON1) | Bioorg Med Chem Lett 13: 1623-6 (2003) BindingDB Entry DOI: 10.7270/Q23B60P7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serum paraoxonase/arylesterase 1 (Homo sapiens (Human)) | BDBM189358 (Asta Z 4942 | Ifosfamide | Iphosphamide | N,3-bis(...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem | Article PubMed | 8.97E+6 | n/a | 2.33E+7 | n/a | n/a | n/a | n/a | 10.5 | n/a |
Ahi Evran University | Assay Description Paraoxonase enzyme activity was determined at 25 °C with paraoxon (1 mM) in 50 mM glycine-NaOH (pH 10.5) containing 1 mM CaCl2. The enzyme assay was ... | Chem Biol Drug Des 88: 188-96 (2016) Article DOI: 10.1111/cbdd.12746 BindingDB Entry DOI: 10.7270/Q2SB44JJ | |||||||||||
More data for this Ligand-Target Pair |