Found 52 hits Enz. Inhib. hit(s) with all data for entry = 50043677 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068755
(2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C15H12N2O2/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(18)8-6-10/h2-8,18H,1H3,(H,16,17,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068766
(2-(4-Amino-phenyl)-8-methyl-3H-quinazolin-4-one | ...)Show InChI InChI=1S/C15H13N3O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,16H2,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of tankyrase2 (unknown origin) |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50444543
(CHEMBL3098937)Show InChI InChI=1S/C15H11BrN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50444545
(CHEMBL3098940)Show InChI InChI=1S/C16H14N2O/c1-10-6-8-12(9-7-10)15-17-14-11(2)4-3-5-13(14)16(19)18-15/h3-9H,1-2H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068765
(8-Methyl-2-(4-trifluoromethyl-phenyl)-3H-quinazoli...)Show InChI InChI=1S/C16H11F3N2O/c1-9-3-2-4-12-13(9)20-14(21-15(12)22)10-5-7-11(8-6-10)16(17,18)19/h2-8H,1H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of tankyrase1 (unknown origin) |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068762
(2-(4-Methoxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C16H14N2O2/c1-10-4-3-5-13-14(10)17-15(18-16(13)19)11-6-8-12(20-2)9-7-11/h3-9H,1-2H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068752
(8-Methyl-2-(4-nitro-phenyl)-3H-quinazolin-4-one | ...)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O3/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(8-6-10)18(20)21/h2-8H,1H3,(H,16,17,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50444543
(CHEMBL3098937)Show InChI InChI=1S/C15H11BrN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068752
(8-Methyl-2-(4-nitro-phenyl)-3H-quinazolin-4-one | ...)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O3/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(8-6-10)18(20)21/h2-8H,1H3,(H,16,17,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50444544
(CHEMBL3098939)Show InChI InChI=1S/C15H11ClN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068766
(2-(4-Amino-phenyl)-8-methyl-3H-quinazolin-4-one | ...)Show InChI InChI=1S/C15H13N3O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,16H2,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50444545
(CHEMBL3098940)Show InChI InChI=1S/C16H14N2O/c1-10-6-8-12(9-7-10)15-17-14-11(2)4-3-5-13(14)16(19)18-15/h3-9H,1-2H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50444544
(CHEMBL3098939)Show InChI InChI=1S/C15H11ClN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068762
(2-(4-Methoxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C16H14N2O2/c1-10-4-3-5-13-14(10)17-15(18-16(13)19)11-6-8-12(20-2)9-7-11/h3-9H,1-2H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50444542
(CHEMBL3098938)Show InChI InChI=1S/C15H11FN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50068758
(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)Show InChI InChI=1S/C15H12N2O/c1-10-6-5-9-12-13(10)16-14(17-15(12)18)11-7-3-2-4-8-11/h2-9H,1H3,(H,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068758
(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)Show InChI InChI=1S/C15H12N2O/c1-10-6-5-9-12-13(10)16-14(17-15(12)18)11-7-3-2-4-8-11/h2-9H,1H3,(H,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50444541
(CHEMBL3098935)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(CNC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C24H21N3O3/c1-16-6-5-9-20-21(16)26-22(27-23(20)28)19-12-10-17(11-13-19)14-25-24(29)30-15-18-7-3-2-4-8-18/h2-13H,14-15H2,1H3,(H,25,29)(H,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50444542
(CHEMBL3098938)Show InChI InChI=1S/C15H11FN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068765
(8-Methyl-2-(4-trifluoromethyl-phenyl)-3H-quinazoli...)Show InChI InChI=1S/C16H11F3N2O/c1-9-3-2-4-12-13(9)20-14(21-15(12)22)10-5-7-11(8-6-10)16(17,18)19/h2-8H,1H3,(H,20,21,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50068755
(2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C15H12N2O2/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(18)8-6-10/h2-8,18H,1H3,(H,16,17,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-1
(Homo sapiens (Human)) | BDBM50444541
(CHEMBL3098935)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(CNC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C24H21N3O3/c1-16-6-5-9-20-21(16)26-22(27-23(20)28)19-12-10-17(11-13-19)14-25-24(29)30-15-18-7-3-2-4-8-18/h2-13H,14-15H2,1H3,(H,25,29)(H,26,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase1 after 30 mins by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase tankyrase-2
(Homo sapiens (Human)) | BDBM50005187
(CHEMBL3099815)Show InChI InChI=1S/C16H15N3O.BrH/c1-10-3-2-4-13-14(10)18-15(19-16(13)20)12-7-5-11(9-17)6-8-12;/h2-8H,9,17H2,1H3,(H,18,19,20);1H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human tankyrase2 after 2 hrs by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068752
(8-Methyl-2-(4-nitro-phenyl)-3H-quinazolin-4-one | ...)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O3/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(8-6-10)18(20)21/h2-8H,1H3,(H,16,17,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068766
(2-(4-Amino-phenyl)-8-methyl-3H-quinazolin-4-one | ...)Show InChI InChI=1S/C15H13N3O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,16H2,1H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 504 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50444545
(CHEMBL3098940)Show InChI InChI=1S/C16H14N2O/c1-10-6-8-12(9-7-10)15-17-14-11(2)4-3-5-13(14)16(19)18-15/h3-9H,1-2H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 685 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068758
(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)Show InChI InChI=1S/C15H12N2O/c1-10-6-5-9-12-13(10)16-14(17-15(12)18)11-7-3-2-4-8-11/h2-9H,1H3,(H,16,17,18) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 795 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068762
(2-(4-Methoxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C16H14N2O2/c1-10-4-3-5-13-14(10)17-15(18-16(13)19)11-6-8-12(20-2)9-7-11/h3-9H,1-2H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 891 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068755
(2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C15H12N2O2/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(18)8-6-10/h2-8,18H,1H3,(H,16,17,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50068765
(8-Methyl-2-(4-trifluoromethyl-phenyl)-3H-quinazoli...)Show InChI InChI=1S/C16H11F3N2O/c1-9-3-2-4-12-13(9)20-14(21-15(12)22)10-5-7-11(8-6-10)16(17,18)19/h2-8H,1H3,(H,20,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50444543
(CHEMBL3098937)Show InChI InChI=1S/C15H11BrN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50444541
(CHEMBL3098935)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(CNC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C24H21N3O3/c1-16-6-5-9-20-21(16)26-22(27-23(20)28)19-12-10-17(11-13-19)14-25-24(29)30-15-18-7-3-2-4-8-18/h2-13H,14-15H2,1H3,(H,25,29)(H,26,27,28) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50444544
(CHEMBL3098939)Show InChI InChI=1S/C15H11ClN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50444542
(CHEMBL3098938)Show InChI InChI=1S/C15H11FN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50068765
(8-Methyl-2-(4-trifluoromethyl-phenyl)-3H-quinazoli...)Show InChI InChI=1S/C16H11F3N2O/c1-9-3-2-4-12-13(9)20-14(21-15(12)22)10-5-7-11(8-6-10)16(17,18)19/h2-8H,1H3,(H,20,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50068755
(2-(4-Hydroxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C15H12N2O2/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(18)8-6-10/h2-8,18H,1H3,(H,16,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50068758
(8-Methyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1247...)Show InChI InChI=1S/C15H12N2O/c1-10-6-5-9-12-13(10)16-14(17-15(12)18)11-7-3-2-4-8-11/h2-9H,1H3,(H,16,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50444545
(CHEMBL3098940)Show InChI InChI=1S/C16H14N2O/c1-10-6-8-12(9-7-10)15-17-14-11(2)4-3-5-13(14)16(19)18-15/h3-9H,1-2H3,(H,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50444542
(CHEMBL3098938)Show InChI InChI=1S/C15H11FN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50444544
(CHEMBL3098939)Show InChI InChI=1S/C15H11ClN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50318567
(2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-5H-thiop...)Show InChI InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50068752
(8-Methyl-2-(4-nitro-phenyl)-3H-quinazolin-4-one | ...)Show SMILES Cc1cccc2c1nc([nH]c2=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C15H11N3O3/c1-9-3-2-4-12-13(9)16-14(17-15(12)19)10-5-7-11(8-6-10)18(20)21/h2-8H,1H3,(H,16,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50444543
(CHEMBL3098937)Show InChI InChI=1S/C15H11BrN2O/c1-9-3-2-4-12-13(9)17-14(18-15(12)19)10-5-7-11(16)8-6-10/h2-8H,1H3,(H,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |
Inosine-5'-monophosphate dehydrogenase 2
(Homo sapiens (Human)) | BDBM50068762
(2-(4-Methoxy-phenyl)-8-methyl-3H-quinazolin-4-one ...)Show InChI InChI=1S/C16H14N2O2/c1-10-4-3-5-13-14(10)17-15(18-16(13)19)11-6-8-12(20-2)9-7-11/h3-9H,1-2H3,(H,17,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bath
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IMPDH2 by spectrophotometry |
ACS Med Chem Lett 4: 1173-7 (2013)
Article DOI: 10.1021/ml400260b BindingDB Entry DOI: 10.7270/Q2XG9SKC |
More data for this Ligand-Target Pair | |