Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50017840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187218 ((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O Show InChI InChI=1S/C11H10Cl3NO5S/c12-5-4-7(10(16)9(14)8(5)13)21(19,20)15-3-1-2-6(15)11(17)18/h4,6,16H,1-3H2,(H,17,18)/t6-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Cytotoxicity against human Huh7 cell line containing HCV genotype 1b replicon				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187221 ((4S)-3-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-1,...) Show SMILES OC(=O)[C@@H]1CSCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C10H9Cl2NO5S2/c11-5-1-6(12)9(14)8(2-5)20(17,18)13-4-19-3-7(13)10(15)16/h1-2,7,14H,3-4H2,(H,15,16)/t7-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187232 ((S)-1-(3-bromo-5-chloro-2-hydroxyphenylsulfonyl)py...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Br)c1O Show InChI InChI=1S/C11H11BrClNO5S/c12-7-4-6(13)5-9(10(7)15)20(18,19)14-3-1-2-8(14)11(16)17/h4-5,8,15H,1-3H2,(H,16,17)/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187217 (2,4-dichloro-6-{[(2S)-2-(2H-tetrazol-5-yl)pyrrolid...) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCC[C@H]1c1nnn[nH]1 Show InChI InChI=1S/C11H11Cl2N5O3S/c12-6-4-7(13)10(19)9(5-6)22(20,21)18-3-1-2-8(18)11-14-16-17-15-11/h4-5,8,19H,1-3H2,(H,14,15,16,17)/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187228 ((S)-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)pyrrol...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C11H11Cl2NO5S/c12-6-4-7(13)10(15)9(5-6)20(18,19)14-3-1-2-8(14)11(16)17/h4-5,8,15H,1-3H2,(H,16,17)/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187233 ((2S)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pyr...) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C11H10Cl2N2O3S/c12-7-4-9(13)11(16)10(5-7)19(17,18)15-3-1-2-8(15)6-14/h4-5,8,16H,1-3H2/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187224 ((4R)-3-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]-1,...) Show SMILES OC(=O)[C@H]1CSCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C10H9Cl2NO5S2/c11-5-1-6(12)9(14)8(2-5)20(17,18)13-4-19-3-7(13)10(15)16/h1-2,7,14H,3-4H2,(H,15,16)/t7-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187230 ((2S)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pip...) Show SMILES OC(=O)[C@@H]1CCCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H13Cl2NO5S/c13-7-5-8(14)11(16)10(6-7)21(19,20)15-4-2-1-3-9(15)12(17)18/h5-6,9,16H,1-4H2,(H,17,18)/t9-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187222 ((S)-1-(3-chloro-5-fluoro-2-hydroxyphenylsulfonyl)p...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(F)cc(Cl)c1O Show InChI InChI=1S/C11H11ClFNO5S/c12-7-4-6(13)5-9(10(7)15)20(18,19)14-3-1-2-8(14)11(16)17/h4-5,8,15H,1-3H2,(H,16,17)/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187225 ((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187229 (2,4-dichloro-6-(pyrrolidin-1-ylsulfonyl)phenol | C...) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C10H11Cl2NO3S/c11-7-5-8(12)10(14)9(6-7)17(15,16)13-3-1-2-4-13/h5-6,14H,1-4H2	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187220 ((S)-1-(2-amino-5-chloro-4-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(N)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-9(14)11(6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187234 ((2R)-1-[(3,5-dichloro-2-hydroxyphenyl)sulfonyl]pip...) Show SMILES OC(=O)[C@H]1CCCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H13Cl2NO5S/c13-7-5-8(14)11(16)10(6-7)21(19,20)15-4-2-1-3-9(15)12(17)18/h5-6,9,16H,1-4H2,(H,17,18)/t9-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187231 ((R)-1-(3,5-dichloro-2-hydroxyphenylsulfonyl)pyrrol...) Show SMILES OC(=O)[C@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C11H11Cl2NO5S/c12-6-4-7(13)10(15)9(5-6)20(18,19)14-3-1-2-8(14)11(16)17/h4-5,8,15H,1-3H2,(H,16,17)/t8-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187226 ((S)-1-(3,5-dichlorophenylsulfonyl)pyrrolidine-2-ca...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C11H11Cl2NO4S/c12-7-4-8(13)6-9(5-7)19(17,18)14-3-1-2-10(14)11(15)16/h4-6,10H,1-3H2,(H,15,16)/t10-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187227 ((S)-1-(2-acetamido-5-chloro-4-methylphenylsulfonyl...) Show SMILES CC(=O)Nc1cc(C)c(Cl)cc1S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C14H17ClN2O5S/c1-8-6-11(16-9(2)18)13(7-10(8)15)23(21,22)17-5-3-4-12(17)14(19)20/h6-7,12H,3-5H2,1-2H3,(H,16,18)(H,19,20)/t12-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187235 ((S)-methyl 1-(3,5-dichloro-2-hydroxyphenylsulfonyl...) Show SMILES COC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1O Show InChI InChI=1S/C12H13Cl2NO5S/c1-20-12(17)9-3-2-4-15(9)21(18,19)10-6-7(13)5-8(14)11(10)16/h5-6,9,16H,2-4H2,1H3/t9-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187219 ((S)-1-(2-benzamido-5-chloro-4-methylphenylsulfonyl...) Show SMILES Cc1cc(NC(=O)c2ccccc2)c(cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C19H19ClN2O5S/c1-12-10-15(21-18(23)13-6-3-2-4-7-13)17(11-14(12)20)28(26,27)22-9-5-8-16(22)19(24)25/h2-4,6-7,10-11,16H,5,8-9H2,1H3,(H,21,23)(H,24,25)/t16-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187223 ((S)-1-(2-aminophenylsulfonyl)pyrrolidine-2-carboxy...) Show SMILES Nc1ccccc1S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C11H14N2O4S/c12-8-4-1-2-6-10(8)18(16,17)13-7-3-5-9(13)11(14)15/h1-2,4,6,9H,3,5,7,12H2,(H,14,15)/t9-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus)	BDBM50187225 ((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV helicase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50187225 ((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HIV reverse transcriptase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
DNA polymerase beta (Homo sapiens (Human))	BDBM50187225 ((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human polymerase beta				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
DNA polymerase alpha catalytic subunit (Homo sapiens (Human))	BDBM50187225 ((S)-1-(2-amino-4-chloro-5-methylphenylsulfonyl)pyr...) Show SMILES Cc1cc(c(N)cc1Cl)S(=O)(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C12H15ClN2O4S/c1-7-5-11(9(14)6-8(7)13)20(18,19)15-4-2-3-10(15)12(16)17/h5-6,10H,2-4,14H2,1H3,(H,16,17)/t10-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of calf thymus polymerase alpha				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187218 ((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...) Show SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O Show InChI InChI=1S/C11H10Cl3NO5S/c12-5-4-7(10(16)9(14)8(5)13)21(19,20)15-3-1-2-6(15)11(17)18/h4,6,16H,1-3H2,(H,17,18)/t6-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Cytotoxicity against human Huh7 cell line containing HCV genotype 1b replicon				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
					More data for this Ligand-Target Pair