Found 72 hits Enz. Inhib. hit(s) with all data for entry = 50015169 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152565
(4-(4-Chloro-4''-methoxy-biphenyl-3-yl)-2,4-dioxo-b...)Show SMILES COc1ccc(cc1)-c1ccc(Cl)c(c1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C17H13ClO5/c1-23-12-5-2-10(3-6-12)11-4-7-14(18)13(8-11)15(19)9-16(20)17(21)22/h2-8H,9H2,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152557
(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H9F3O5S/c16-15(17,18)23-9-3-1-8(2-4-9)12-5-6-13(24-12)10(19)7-11(20)14(21)22/h1-6H,7H2,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152558
(4-(4-Chloro-biphenyl-3-yl)-2,4-dioxo-butyric acid ...)Show InChI InChI=1S/C16H11ClO4/c17-13-7-6-11(10-4-2-1-3-5-10)8-12(13)14(18)9-15(19)16(20)21/h1-8H,9H2,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152562
(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)Show InChI InChI=1S/C16H10Cl2O4/c17-11-4-1-9(2-5-11)10-3-6-12(13(18)7-10)14(19)8-15(20)16(21)22/h1-7H,8H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152557
(2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophe...)Show SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H9F3O5S/c16-15(17,18)23-9-3-1-8(2-4-9)12-5-6-13(24-12)10(19)7-11(20)14(21)22/h1-6H,7H2,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152553
(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)Show InChI InChI=1S/C14H8ClFO4S/c15-8-2-1-7(5-9(8)16)12-3-4-13(21-12)10(17)6-11(18)14(19)20/h1-5H,6H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152565
(4-(4-Chloro-4''-methoxy-biphenyl-3-yl)-2,4-dioxo-b...)Show SMILES COc1ccc(cc1)-c1ccc(Cl)c(c1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C17H13ClO5/c1-23-12-5-2-10(3-6-12)11-4-7-14(18)13(8-11)15(19)9-16(20)17(21)22/h2-8H,9H2,1H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152553
(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)Show InChI InChI=1S/C14H8ClFO4S/c15-8-2-1-7(5-9(8)16)12-3-4-13(21-12)10(17)6-11(18)14(19)20/h1-5H,6H2,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152564
(4-[5-(4-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C14H9ClO5/c15-9-3-1-8(2-4-9)12-5-6-13(20-12)10(16)7-11(17)14(18)19/h1-6H,7H2,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152558
(4-(4-Chloro-biphenyl-3-yl)-2,4-dioxo-butyric acid ...)Show InChI InChI=1S/C16H11ClO4/c17-13-7-6-11(10-4-2-1-3-5-10)8-12(13)14(18)9-15(19)16(20)21/h1-8H,9H2,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152581
(4-(4''-Methoxy-biphenyl-3-yl)-2,4-dioxo-butyric ac...)Show InChI InChI=1S/C17H14O5/c1-22-14-7-5-11(6-8-14)12-3-2-4-13(9-12)15(18)10-16(19)17(20)21/h2-9H,10H2,1H3,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152580
(4-[5-(4-Ethoxy-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C16H14O6/c1-2-21-11-5-3-10(4-6-11)14-7-8-15(22-14)12(17)9-13(18)16(19)20/h3-8H,2,9H2,1H3,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152567
(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)Show InChI InChI=1S/C9H5F3O4S/c10-9(11,12)7-2-1-6(17-7)4(13)3-5(14)8(15)16/h1-2H,3H2,(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152581
(4-(4''-Methoxy-biphenyl-3-yl)-2,4-dioxo-butyric ac...)Show InChI InChI=1S/C17H14O5/c1-22-14-7-5-11(6-8-14)12-3-2-4-13(9-12)15(18)10-16(19)17(20)21/h2-9H,10H2,1H3,(H,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152559
(4-Biphenyl-4-yl-2,4-dioxo-butyric acid | CHEMBL182...)Show InChI InChI=1S/C16H12O4/c17-14(10-15(18)16(19)20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9H,10H2,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152563
(2,4-Dioxo-4-(5-phenyl-furan-2-yl)-butyric acid | C...)Show InChI InChI=1S/C14H10O5/c15-10(8-11(16)14(17)18)13-7-6-12(19-13)9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50115581
((Z)-2-Hydroxy-4-oxo-4-(4-phenoxy-phenyl)-but-2-eno...)Show InChI InChI=1S/C16H12O5/c17-14(10-15(18)16(19)20)11-6-8-13(9-7-11)21-12-4-2-1-3-5-12/h1-9H,10H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152562
(4-(3,4''-Dichloro-biphenyl-4-yl)-2,4-dioxo-butyric...)Show InChI InChI=1S/C16H10Cl2O4/c17-11-4-1-9(2-5-11)10-3-6-12(13(18)7-10)14(19)8-15(20)16(21)22/h1-7H,8H2,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152563
(2,4-Dioxo-4-(5-phenyl-furan-2-yl)-butyric acid | C...)Show InChI InChI=1S/C14H10O5/c15-10(8-11(16)14(17)18)13-7-6-12(19-13)9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152577
(4-(2,5-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-5-1-2-7(12)6(3-5)8(13)4-9(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152551
(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C14H9ClO5/c15-9-4-2-1-3-8(9)12-5-6-13(20-12)10(16)7-11(17)14(18)19/h1-6H,7H2,(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152572
(2,4-Dioxo-4-(5-phenyl-thiophen-2-yl)-butyric acid ...)Show InChI InChI=1S/C14H10O4S/c15-10(8-11(16)14(17)18)13-7-6-12(19-13)9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50115581
((Z)-2-Hydroxy-4-oxo-4-(4-phenoxy-phenyl)-but-2-eno...)Show InChI InChI=1S/C16H12O5/c17-14(10-15(18)16(19)20)11-6-8-13(9-7-11)21-12-4-2-1-3-5-12/h1-9H,10H2,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152567
(2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-buty...)Show InChI InChI=1S/C9H5F3O4S/c10-9(11,12)7-2-1-6(17-7)4(13)3-5(14)8(15)16/h1-2H,3H2,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152566
(4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...)Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(o1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C18H18O5/c1-18(2,3)12-6-4-11(5-7-12)15-8-9-16(23-15)13(19)10-14(20)17(21)22/h4-9H,10H2,1-3H3,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152548
(4-Biphenyl-3-yl-2,4-dioxo-butyric acid | CHEMBL185...)Show InChI InChI=1S/C16H12O4/c17-14(10-15(18)16(19)20)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-9H,10H2,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152559
(4-Biphenyl-4-yl-2,4-dioxo-butyric acid | CHEMBL182...)Show InChI InChI=1S/C16H12O4/c17-14(10-15(18)16(19)20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9H,10H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152554
(4-(2-Chloro-phenyl)-2,4-dioxo-butyric acid | CHEMB...)Show InChI InChI=1S/C10H7ClO4/c11-7-4-2-1-3-6(7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152548
(4-Biphenyl-3-yl-2,4-dioxo-butyric acid | CHEMBL185...)Show InChI InChI=1S/C16H12O4/c17-14(10-15(18)16(19)20)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-9H,10H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152569
(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)Show InChI InChI=1S/C16H12O5/c17-14(10-15(18)16(19)20)11-5-4-8-13(9-11)21-12-6-2-1-3-7-12/h1-9H,10H2,(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152568
(4-(2,4-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-5-1-2-6(7(12)3-5)8(13)4-9(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50083940
(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)Show InChI InChI=1S/C10H7ClO4/c11-7-3-1-2-6(4-7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152577
(4-(2,5-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-5-1-2-7(12)6(3-5)8(13)4-9(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152569
(2,4-Dioxo-4-(3-phenoxy-phenyl)-butyric acid | CHEM...)Show InChI InChI=1S/C16H12O5/c17-14(10-15(18)16(19)20)11-5-4-8-13(9-11)21-12-6-2-1-3-7-12/h1-9H,10H2,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152572
(2,4-Dioxo-4-(5-phenyl-thiophen-2-yl)-butyric acid ...)Show InChI InChI=1S/C14H10O4S/c15-10(8-11(16)14(17)18)13-7-6-12(19-13)9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152568
(4-(2,4-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-5-1-2-6(7(12)3-5)8(13)4-9(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152574
(2,4-Dioxo-4-thiophen-2-yl-butyric acid | CHEMBL183...)Show InChI InChI=1S/C8H6O4S/c9-5(4-6(10)8(11)12)7-2-1-3-13-7/h1-3H,4H2,(H,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152564
(4-[5-(4-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C14H9ClO5/c15-9-3-1-8(2-4-9)12-5-6-13(20-12)10(16)7-11(17)14(18)19/h1-6H,7H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152580
(4-[5-(4-Ethoxy-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C16H14O6/c1-2-21-11-5-3-10(4-6-11)14-7-8-15(22-14)12(17)9-13(18)16(19)20/h3-8H,2,9H2,1H3,(H,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152551
(4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyr...)Show InChI InChI=1S/C14H9ClO5/c15-9-4-2-1-3-8(9)12-5-6-13(20-12)10(16)7-11(17)14(18)19/h1-6H,7H2,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50083934
(4-(4-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)Show InChI InChI=1S/C10H7ClO4/c11-7-3-1-6(2-4-7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152575
(2,4-Dioxo-4-o-tolyl-butyric acid | CHEMBL1829214 |...)Show InChI InChI=1S/C11H10O4/c1-7-4-2-3-5-8(7)9(12)6-10(13)11(14)15/h2-5H,6H2,1H3,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50083940
(4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)Show InChI InChI=1S/C10H7ClO4/c11-7-3-1-2-6(4-7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152566
(4-[5-(4-tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-b...)Show SMILES CC(C)(C)c1ccc(cc1)-c1ccc(o1)C(=O)CC(=O)C(O)=O Show InChI InChI=1S/C18H18O5/c1-18(2,3)12-6-4-11(5-7-12)15-8-9-16(23-15)13(19)10-14(20)17(21)22/h4-9H,10H2,1-3H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152579
(4-(2-Fluoro-phenyl)-2,4-dioxo-butyric acid | CHEMB...)Show InChI InChI=1S/C10H7FO4/c11-7-4-2-1-3-6(7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152552
(4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-6-3-1-2-5(9(6)12)7(13)4-8(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50083934
(4-(4-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic ac...)Show InChI InChI=1S/C10H7ClO4/c11-7-3-1-6(2-4-7)8(12)5-9(13)10(14)15/h1-4H,5H2,(H,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
DNA excision repair protein ERCC-5
(Homo sapiens (Human)) | BDBM50152552
(4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)Show InChI InChI=1S/C10H6Cl2O4/c11-6-3-1-2-5(9(6)12)7(13)4-8(14)10(15)16/h1-3H,4H2,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Xeroderma pigmentosum G |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50115579
((Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid | 2-...)Show InChI InChI=1S/C10H8O4/c11-8(6-9(12)10(13)14)7-4-2-1-3-5-7/h1-5H,6H2,(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |
Flap endonuclease 1
(Homo sapiens (Human)) | BDBM50152570
((8-Hydroxy-[1,6]naphthyridin-7-yl)-(4-phenoxy-phen...)Show InChI InChI=1S/C21H14N2O3/c24-20(19-21(25)18-15(13-23-19)5-4-12-22-18)14-8-10-17(11-9-14)26-16-6-2-1-3-7-16/h1-13,25H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Athersys, Inc.
Curated by ChEMBL
| Assay Description Concentration required for 50% inhibition of Flap endonuclease-1 |
Bioorg Med Chem Lett 14: 4915-8 (2004)
Article DOI: 10.1016/j.bmcl.2004.07.028 BindingDB Entry DOI: 10.7270/Q2ZC82BF |
More data for this Ligand-Target Pair | |