Found 53 hits Enz. Inhib. hit(s) with all data for entry = 50039780 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384024
(CHEMBL2032280 | CHEMBL2079349)Show SMILES Cc1c(O)ccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-18(28)3-2-17-19(12)29-21(26-17)16-8-13(9-24-20(16)22)14-10-25-27(11-14)15-4-6-23-7-5-15/h2-3,8-11,15,23,28H,4-7H2,1H3,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384038
(CHEMBL2032155)Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384038
(CHEMBL2032155)Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O/c26-24-20(12-16(13-29-24)17-14-30-32(15-17)18-7-10-27-11-8-18)25-31-22-6-3-4-19(23(22)33-25)21-5-1-2-9-28-21/h1-6,9,12-15,18,27H,7-8,10-11H2,(H2,26,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384004
(CHEMBL2032276)Show SMILES Cc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-6-19-17(8-18(12)28)26-21(29-19)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384027
(CHEMBL2032277)Show SMILES Cc1cc2oc(nc2c(C)c1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H24N6O2/c1-12-7-18-19(13(2)20(12)29)27-22(30-18)17-8-14(9-25-21(17)23)15-10-26-28(11-15)16-3-5-24-6-4-16/h7-11,16,24,29H,3-6H2,1-2H3,(H2,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384019
(CHEMBL2032285 | CHEMBL2079397)Show SMILES Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H21N7O/c21-14-1-2-17-18(8-14)28-20(26-17)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6,21H2,(H2,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384023
(CHEMBL2032281)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cccnc3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O2/c26-24-19(10-16(12-29-24)17-13-30-32(14-17)18-5-8-27-9-6-18)25-31-20-3-4-21(33)22(23(20)34-25)15-2-1-7-28-11-15/h1-4,7,10-14,18,27,33H,5-6,8-9H2,(H2,26,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384006
(CHEMBL2032274)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384026
(CHEMBL2032278)Show SMILES CCc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H24N6O2/c1-2-13-8-20-18(9-19(13)29)27-22(30-20)17-7-14(10-25-21(17)23)15-11-26-28(12-15)16-3-5-24-6-4-16/h7-12,16,24,29H,2-6H2,1H3,(H2,23,25) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384022
(CHEMBL2032282)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cnccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H22N8O2/c25-23-17(9-14(10-29-23)15-11-30-32(13-15)16-3-5-26-6-4-16)24-31-18-1-2-20(33)21(22(18)34-24)19-12-27-7-8-28-19/h1-2,7-13,16,26,33H,3-6H2,(H2,25,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384026
(CHEMBL2032278)Show SMILES CCc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H24N6O2/c1-2-13-8-20-18(9-19(13)29)27-22(30-20)17-7-14(10-25-21(17)23)15-11-26-28(12-15)16-3-5-24-6-4-16/h7-12,16,24,29H,2-6H2,1H3,(H2,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384045
(CHEMBL2032298)Show SMILES Cn1cc(cn1)-c1cnc(N)c(c1)-c1nc2cccc(-c3ccccn3)c2o1 Show InChI InChI=1S/C21H16N6O/c1-27-12-14(11-25-27)13-9-16(20(22)24-10-13)21-26-18-7-4-5-15(19(18)28-21)17-6-2-3-8-23-17/h2-12H,1H3,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Macrophage-stimulating protein receptor
(Homo sapiens (Human)) | BDBM50384006
(CHEMBL2032274)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of Ron |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384019
(CHEMBL2032285 | CHEMBL2079397)Show SMILES Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H21N7O/c21-14-1-2-17-18(8-14)28-20(26-17)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6,21H2,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384021
(CHEMBL2032283 | CHEMBL2079205)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3ccccc3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H24N6O2/c27-25-20(12-17(13-29-25)18-14-30-32(15-18)19-8-10-28-11-9-19)26-31-21-6-7-22(33)23(24(21)34-26)16-4-2-1-3-5-16/h1-7,12-15,19,28,33H,8-11H2,(H2,27,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384006
(CHEMBL2032274)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384029
(CHEMBL2032273)Show SMILES Nc1ncc(cc1-c1nc2cc(O)ccc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-8-15(27)1-2-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384030
(CHEMBL2032272 | CHEMBL2079392)Show SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H22N8O2/c25-22-19(10-15(12-29-22)16-13-30-32(14-16)17-4-8-26-9-5-17)23-31-20-3-2-18(11-21(20)34-23)33-24-27-6-1-7-28-24/h1-3,6-7,10-14,17,26H,4-5,8-9H2,(H2,25,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384004
(CHEMBL2032276)Show SMILES Cc1cc2oc(nc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-6-19-17(8-18(12)28)26-21(29-19)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384040
(CHEMBL2032153)Show SMILES Nc1ncc(cc1-c1nc2ccc(cc2o1)-c1cccnc1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C25H23N7O/c26-24-21(10-18(13-29-24)19-14-30-32(15-19)20-5-8-27-9-6-20)25-31-22-4-3-16(11-23(22)33-25)17-2-1-7-28-12-17/h1-4,7,10-15,20,27H,5-6,8-9H2,(H2,26,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384008
(CHEMBL2032296)Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2c(C)c(O)c(C)cc2o1 Show InChI InChI=1S/C24H26N6O3/c1-13-8-20-21(14(2)22(13)32)28-24(33-20)19-9-16(10-26-23(19)25)17-11-27-30(12-17)18-4-6-29(7-5-18)15(3)31/h8-12,18,32H,4-7H2,1-3H3,(H2,25,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384031
(CHEMBL2032162)Show SMILES Nc1ncc(cc1-c1nc2ccc(Oc3ccncn3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H22N8O2/c25-23-19(9-15(11-28-23)16-12-30-32(13-16)17-3-6-26-7-4-17)24-31-20-2-1-18(10-21(20)34-24)33-22-5-8-27-14-29-22/h1-2,5,8-14,17,26H,3-4,6-7H2,(H2,25,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384024
(CHEMBL2032280 | CHEMBL2079349)Show SMILES Cc1c(O)ccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-18(28)3-2-17-19(12)29-21(26-17)16-8-13(9-24-20(16)22)14-10-25-27(11-14)15-4-6-23-7-5-15/h2-3,8-11,15,23,28H,4-7H2,1H3,(H2,22,24) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50384022
(CHEMBL2032282)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3cnccn3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H22N8O2/c25-23-17(9-14(10-29-23)15-11-30-32(13-15)16-3-5-26-6-4-16)24-31-18-1-2-20(33)21(22(18)34-24)19-12-27-7-8-28-19/h1-2,7-13,16,26,33H,3-6H2,(H2,25,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384043
(CHEMBL2032150)Show SMILES Nc1ncc(cc1-c1nc2cc(Cl)cc(F)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H18ClFN6O/c21-13-6-16(22)18-17(7-13)27-20(29-18)15-5-11(8-25-19(15)23)12-9-26-28(10-12)14-1-3-24-4-2-14/h5-10,14,24H,1-4H2,(H2,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384014
(CHEMBL2032290)Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C28H28N8O4S/c1-17-2-5-22(6-3-17)41(38,39)35-28(37)33-20-4-7-24-25(13-20)40-27(34-24)23-12-18(14-31-26(23)29)19-15-32-36(16-19)21-8-10-30-11-9-21/h2-7,12-16,21,30H,8-11H2,1H3,(H2,29,31)(H2,33,35,37) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384021
(CHEMBL2032283 | CHEMBL2079205)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)c(-c3ccccc3)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H24N6O2/c27-25-20(12-17(13-29-25)18-14-30-32(15-18)19-8-10-28-11-9-19)26-31-21-6-7-22(33)23(24(21)34-26)16-4-2-1-3-5-16/h1-7,12-15,19,28,33H,8-11H2,(H2,27,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384009
(CHEMBL2032295)Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2cc(O)c(C)cc2o1 Show InChI InChI=1S/C23H24N6O3/c1-13-7-21-19(9-20(13)31)27-23(32-21)18-8-15(10-25-22(18)24)16-11-26-29(12-16)17-3-5-28(6-4-17)14(2)30/h7-12,17,31H,3-6H2,1-2H3,(H2,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384007
(CHEMBL2032297)Show SMILES Nc1ncc(cc1-c1nc2cccc(-c3ccccn3)c2o1)-c1cnn(CCO)c1 Show InChI InChI=1S/C22H18N6O2/c23-21-17(10-14(11-25-21)15-12-26-28(13-15)8-9-29)22-27-19-6-3-4-16(20(19)30-22)18-5-1-2-7-24-18/h1-7,10-13,29H,8-9H2,(H2,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384044
(CHEMBL2032149)Show SMILES Nc1ncc(cc1-c1nc2cc(Cl)ccc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H19ClN6O/c21-14-1-2-18-17(8-14)26-20(28-18)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6H2,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384020
(CHEMBL2032284 | CHEMBL2079522)Show SMILES Nc1ccc2oc(nc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H21N7O/c21-14-1-2-18-17(8-14)26-20(28-18)16-7-12(9-24-19(16)22)13-10-25-27(11-13)15-3-5-23-6-4-15/h1-2,7-11,15,23H,3-6,21H2,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384032
(CHEMBL2032161)Show SMILES Nc1ncc(cc1-c1nc2ccc(Nc3ncccn3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C24H23N9O/c25-22-19(10-15(12-29-22)16-13-30-33(14-16)18-4-8-26-9-5-18)23-32-20-3-2-17(11-21(20)34-23)31-24-27-6-1-7-28-24/h1-3,6-7,10-14,18,26H,4-5,8-9H2,(H2,25,29)(H,27,28,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384016
(CHEMBL2032288)Show SMILES Nc1ncc(cc1-c1nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H24FN7O3S/c27-18-1-4-21(5-2-18)38(35,36)33-19-3-6-23-24(12-19)37-26(32-23)22-11-16(13-30-25(22)28)17-14-31-34(15-17)20-7-9-29-10-8-20/h1-6,11-15,20,29,33H,7-10H2,(H2,28,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384037
(CHEMBL2032156)Show SMILES COc1ccc(cc1)-c1cccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C27H26N6O2/c1-34-21-7-5-17(6-8-21)22-3-2-4-24-25(22)35-27(32-24)23-13-18(14-30-26(23)28)19-15-31-33(16-19)20-9-11-29-12-10-20/h2-8,13-16,20,29H,9-12H2,1H3,(H2,28,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50321421
(3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-p...)Show SMILES Nc1ncc(cc1-c1nc2ccccc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O/c21-19-16(20-25-17-3-1-2-4-18(17)27-20)9-13(10-23-19)14-11-24-26(12-14)15-5-7-22-8-6-15/h1-4,9-12,15,22H,5-8H2,(H2,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384017
(CHEMBL2032287)Show SMILES CS(=O)(=O)Nc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H23N7O3S/c1-32(29,30)27-15-2-3-18-19(9-15)31-21(26-18)17-8-13(10-24-20(17)22)14-11-25-28(12-14)16-4-6-23-7-5-16/h2-3,8-12,16,23,27H,4-7H2,1H3,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384011
(CHEMBL2032293)Show SMILES Nc1ncc(cc1-c1nc2ccc(F)cc2o1)-c1cnn(c1)C1CCN(CCO)CC1 Show InChI InChI=1S/C22H23FN6O2/c23-16-1-2-19-20(10-16)31-22(27-19)18-9-14(11-25-21(18)24)15-12-26-29(13-15)17-3-5-28(6-4-17)7-8-30/h1-2,9-13,17,30H,3-8H2,(H2,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50384006
(CHEMBL2032274)Show SMILES Nc1ncc(cc1-c1nc2ccc(O)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-16(20-25-17-2-1-15(27)8-18(17)28-20)7-12(9-23-19)13-10-24-26(11-13)14-3-5-22-6-4-14/h1-2,7-11,14,22,27H,3-6H2,(H2,21,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of Aurora A |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384028
(CHEMBL2032275)Show SMILES Nc1ncc(cc1-c1nc2cccc(O)c2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C20H20N6O2/c21-19-15(20-25-16-2-1-3-17(27)18(16)28-20)8-12(9-23-19)13-10-24-26(11-13)14-4-6-22-7-5-14/h1-3,8-11,14,22,27H,4-7H2,(H2,21,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384041
(CHEMBL2032152)Show SMILES CC(O)c1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H24N6O2/c1-13(29)14-2-3-19-20(9-14)30-22(27-19)18-8-15(10-25-21(18)23)16-11-26-28(12-16)17-4-6-24-7-5-17/h2-3,8-13,17,24,29H,4-7H2,1H3,(H2,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384018
(CHEMBL2032286)Show SMILES Nc1ncc(cc1-c1nc2ccc(NC(=O)Nc3ccccc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C27H26N8O2/c28-25-22(12-17(14-30-25)18-15-31-35(16-18)21-8-10-29-11-9-21)26-34-23-7-6-20(13-24(23)37-26)33-27(36)32-19-4-2-1-3-5-19/h1-7,12-16,21,29H,8-11H2,(H2,28,30)(H2,32,33,36) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384036
(CHEMBL2032157)Show SMILES CC(C)Nc1cccc2nc(oc12)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C23H27N7O/c1-14(2)28-19-4-3-5-20-21(19)31-23(29-20)18-10-15(11-26-22(18)24)16-12-27-30(13-16)17-6-8-25-9-7-17/h3-5,10-14,17,25,28H,6-9H2,1-2H3,(H2,24,26) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384033
(CHEMBL2032160)Show SMILES CCCNc1ccc2nc(oc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C23H27N7O/c1-2-7-26-17-3-4-20-21(11-17)31-23(29-20)19-10-15(12-27-22(19)24)16-13-28-30(14-16)18-5-8-25-9-6-18/h3-4,10-14,18,25-26H,2,5-9H2,1H3,(H2,24,27) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384035
(CHEMBL2032158 | CHEMBL2078645)Show SMILES CNc1ccc2oc(nc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H23N7O/c1-23-15-2-3-19-18(9-15)27-21(29-19)17-8-13(10-25-20(17)22)14-11-26-28(12-14)16-4-6-24-7-5-16/h2-3,8-12,16,23-24H,4-7H2,1H3,(H2,22,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384025
(CHEMBL2032279 | CHEMBL2079395)Show SMILES Cc1cc2nc(oc2cc1O)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C21H22N6O2/c1-12-6-17-19(8-18(12)28)29-21(26-17)16-7-13(9-24-20(16)22)14-10-25-27(11-14)15-2-4-23-5-3-15/h6-11,15,23,28H,2-5H2,1H3,(H2,22,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384039
(CHEMBL2032154)Show SMILES Nc1ncc(cc1-c1nc2ccc(cc2o1)-c1cc[nH]n1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C23H22N8O/c24-22-18(23-29-20-2-1-14(10-21(20)32-23)19-5-8-27-30-19)9-15(11-26-22)16-12-28-31(13-16)17-3-6-25-7-4-17/h1-2,5,8-13,17,25H,3-4,6-7H2,(H2,24,26)(H,27,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384010
(CHEMBL2032294)Show SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccc(Cl)cc2o1 Show InChI InChI=1S/C22H21ClN6O2/c1-13(30)28-6-4-17(5-7-28)29-12-15(11-26-29)14-8-18(21(24)25-10-14)22-27-19-3-2-16(23)9-20(19)31-22/h2-3,8-12,17H,4-7H2,1H3,(H2,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384012
(CHEMBL2032292)Show SMILES CN1CCC(CC1)n1cc(cn1)-c1cnc(N)c(c1)-c1nc2ccc(F)cc2o1 Show InChI InChI=1S/C21H21FN6O/c1-27-6-4-16(5-7-27)28-12-14(11-25-28)13-8-17(20(23)24-10-13)21-26-18-3-2-15(22)9-19(18)29-21/h2-3,8-12,16H,4-7H2,1H3,(H2,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384015
(CHEMBL2032289)Show SMILES Nc1ncc(cc1-c1nc2ccc(Nc3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C26H24FN7O/c27-18-1-3-19(4-2-18)32-20-5-6-23-24(12-20)35-26(33-23)22-11-16(13-30-25(22)28)17-14-31-34(15-17)21-7-9-29-10-8-21/h1-6,11-15,21,29,32H,7-10H2,(H2,28,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50384034
(CHEMBL2032159 | CHEMBL2032299)Show SMILES CC(=O)Nc1ccc2oc(nc2c1)-c1cc(cnc1N)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C22H23N7O2/c1-13(30)27-16-2-3-20-19(9-16)28-22(31-20)18-8-14(10-25-21(18)23)15-11-26-29(12-15)17-4-6-24-7-5-17/h2-3,8-12,17,24H,4-7H2,1H3,(H2,23,25)(H,27,30) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysis |
Bioorg Med Chem Lett 22: 4044-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.04.083 BindingDB Entry DOI: 10.7270/Q2FF3TC4 |
More data for this Ligand-Target Pair | |