Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50373326 (CHEMBL444278) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human P2Y1 receptor | Bioorg Med Chem Lett 18: 3338-43 (2008) Article DOI: 10.1016/j.bmcl.2008.04.028 BindingDB Entry DOI: 10.7270/Q2X34Z95 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50373326 (CHEMBL444278) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]2-chloro-N 6- methyl-( N )-methanocarba-2'-deoxyadenosine 3 ' ,5 '-bis-phosphate from human P2Y1 expressed in baculovirus infecte... | Eur J Med Chem 158: 302-310 (2018) Article DOI: 10.1016/j.ejmech.2018.09.014 BindingDB Entry DOI: 10.7270/Q27H1N8S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50373326 (CHEMBL444278) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK Curated by ChEMBL | Assay Description Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cells | J Med Chem 46: 4974-87 (2003) Article DOI: 10.1021/jm030127+ BindingDB Entry DOI: 10.7270/Q2NS0T9D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM261048 (US9540323, 269 | US9540323, example 269) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.20 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245383 (US9428504, 133) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.20 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245297 (US9428504, 35) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.90 | -49.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50409757 (CHEMBL2112864) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK Curated by ChEMBL | Assay Description Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cells | J Med Chem 46: 4974-87 (2003) Article DOI: 10.1021/jm030127+ BindingDB Entry DOI: 10.7270/Q2NS0T9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260841 (US9540323, 27 | US9540323, example 27) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.10 | -48.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245282 (US9428504, 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.20 | -48.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260928 (US9540323, 119 | US9540323, example 119) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260845 (US9540323, 31 | US9540323, example 31) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245302 (US9428504, 42) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50015276 (CHEMBL3263056 | US9428504, 166 | US9428504, 167) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245275 (US9428504, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260816 (US9540323, 2 | US9540323, example 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.40 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245342 (US9428504, 91) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.40 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260932 (US9540323, 124 | US9540323, example 124) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.40 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245341 (US9428504, 90) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.5 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50409764 (CHEMBL2112867) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK Curated by ChEMBL | Assay Description Inhibition of [3H]-5 binding to P2Y purinoceptor 1 expressed in Sf9 cells | J Med Chem 46: 4974-87 (2003) Article DOI: 10.1021/jm030127+ BindingDB Entry DOI: 10.7270/Q2NS0T9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260843 (US9540323, 29 | US9540323, example 29) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.60 | -48.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245295 (US9428504, 33) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.70 | -48.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245296 (US9428504, 34) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.70 | -48.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245340 (US9428504, 85) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.70 | -48.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245414 (US9428504, 173) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.80 | -48.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50017083 (CHEMBL3287049 | US9428504, 39) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.80 | -48.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245271 (US9428504, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50017021 (CHEMBL3287047 | US9428504, 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Curated by ChEMBL | Assay Description Binding affinity to P2Y1 receptor in human platelets | Bioorg Med Chem Lett 24: 1294-8 (2014) Article DOI: 10.1016/j.bmcl.2014.01.066 BindingDB Entry DOI: 10.7270/Q20G3MQF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260934 (US9540323, 126 | US9540323, example 126) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.10 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260870 (US9540323, 58 | US9540323, example 58) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.10 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50445214 (CHEMBL3104636) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company Curated by ChEMBL | Assay Description Displacement of [33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysis | J Med Chem 56: 9275-95 (2013) Article DOI: 10.1021/jm4013906 BindingDB Entry DOI: 10.7270/Q2KW5HHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245284 (US9428504, 22) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.40 | -47.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50017091 (CHEMBL3287045 | US9428504, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.40 | -47.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245303 (US9428504, 43) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.40 | -47.7 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description Binding reactions were performed in WGA FLASHPLATEs (PerkinElmer Life Sciences, Cat # SMP105A) in a volume of 200 uL containing 45 fmol of P2Y1 recep... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260885 (US9540323, 73 | US9540323, example 73) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.5 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260931 (US9540323, 123 | US9540323, example 123) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.5 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50017087 (CHEMBL3287041 | US9428504, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.5 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50045627 (CHEMBL3314307 | US9540323, 200 | US9540323, exampl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 4.60 | -47.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50445208 (CHEMBL3105199) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company Curated by ChEMBL | Assay Description Displacement of [33P]-2MeS-ADP from human P2Y1 receptor expressed in HEK293 cells after 1 hr by scintillation counting analysis | J Med Chem 56: 9275-95 (2013) Article DOI: 10.1021/jm4013906 BindingDB Entry DOI: 10.7270/Q2KW5HHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260987 (US9540323, 188 | US9540323, example 188) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.70 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260935 (US9540323, 127 | US9540323, example 127) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.70 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260933 (US9540323, 125 | US9540323, example 125) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.80 | -47.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260817 (US9540323, 3 | US9540323, example 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.90 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260996 (US9540323, 212 | US9540323, example 212) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.90 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50045625 (CHEMBL3314305 | US9540323, 198 | US9540323, exampl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 4.90 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245287 (US9428504, 25) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.90 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245320 (US9428504, 63) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.90 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260826 (US9540323, 12 | US9540323, example 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM260866 (US9540323, 53 | US9540323, example 53) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9540323 (2017) BindingDB Entry DOI: 10.7270/Q289141P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM245336 (US9428504, 81) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we... | US Patent US9428504 (2016) BindingDB Entry DOI: 10.7270/Q24748SD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 1 (Homo sapiens (Human)) | BDBM50436912 (CHEMBL2401804) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Displacement of [beta-33P]-2MeS-ADP from human P2Y1 expressed in HEK293 cells after 1 hr by scintillation counting analysis | Bioorg Med Chem Lett 23: 4026-30 (2013) Article DOI: 10.1016/j.bmcl.2013.05.087 BindingDB Entry DOI: 10.7270/Q2D50PC8 | |||||||||||
More data for this Ligand-Target Pair |
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