Compile Data Set for Download or QSAR

Found 215 hits with Last Name = 'sawyer' and Initial = 'js'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029464 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C34H29FO9/c1-2-19-16-25(20-4-7-22(35)8-5-20)27(36)18-30(19)43-15-3-14-42-28-12-9-24-32(39)26-17-21(34(40)41)6-11-29(26)44-33(24)23(28)10-13-31(37)38/h4-9,11-12,16-18,36H,2-3,10,13-15H2,1H3,(H,37,38)(H,40,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029477 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C34H30O9/c1-2-20-17-25(21-7-4-3-5-8-21)27(35)19-30(20)42-16-6-15-41-28-13-10-24-32(38)26-18-22(34(39)40)9-12-29(26)43-33(24)23(28)11-14-31(36)37/h3-5,7-10,12-13,17-19,35H,2,6,11,14-16H2,1H3,(H,36,37)(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50013889 ((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...) Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O |r| Show InChI InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029464 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C34H29FO9/c1-2-19-16-25(20-4-7-22(35)8-5-20)27(36)18-30(19)43-15-3-14-42-28-12-9-24-32(39)26-17-21(34(40)41)6-11-29(26)44-33(24)23(28)10-13-31(37)38/h4-9,11-12,16-18,36H,2-3,10,13-15H2,1H3,(H,37,38)(H,40,41)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029477 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C34H30O9/c1-2-20-17-25(21-7-4-3-5-8-21)27(35)19-30(20)42-16-6-15-41-28-13-10-24-32(38)26-18-22(34(39)40)9-12-29(26)43-33(24)23(28)11-14-31(36)37/h3-5,7-10,12-13,17-19,35H,2,6,11,14-16H2,1H3,(H,36,37)(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029482 (6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...) Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O Show InChI InChI=1S/C30H28O10/c1-3-17-13-21(16(2)31)23(32)15-26(17)39-12-4-11-38-24-9-6-20-28(35)22-14-18(30(36)37)5-8-25(22)40-29(20)19(24)7-10-27(33)34/h5-6,8-9,13-15,32H,3-4,7,10-12H2,1-2H3,(H,33,34)(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029482 (6-[3-(4-Acetyl-2-ethyl-5-hydroxy-phenoxy)-propoxy]...) Show SMILES CCc1cc(C(C)=O)c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O Show InChI InChI=1S/C30H28O10/c1-3-17-13-21(16(2)31)23(32)15-26(17)39-12-4-11-38-24-9-6-20-28(35)22-14-18(30(36)37)5-8-25(22)40-29(20)19(24)7-10-27(33)34/h5-6,8-9,13-15,32H,3-4,7,10-12H2,1-2H3,(H,33,34)(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50013889 ((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...) Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O |r| Show InChI InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029462 (2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)-c2ccc(F)cc2)cccc1S(=O)c1ccccc1C(O)=O Show InChI InChI=1S/C33H33FO6S/c1-3-9-25-29(11-7-13-31(25)41(38)32-12-6-5-10-26(32)33(36)37)39-18-8-19-40-30-21-28(35)27(20-22(30)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligand				J Med Chem 38: 4411-32 (1995) BindingDB Entry DOI: 10.7270/Q20V8BSQ
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50045092 (5-(2-Carboxy-ethyl)-6-[(E)-6-(4-methoxy-phenyl)-he...) Show SMILES COc1ccc(\C=C\CCCCOc2ccc3c(oc4ccc(cc4c3=O)C(O)=O)c2CCC(O)=O)cc1 Show InChI InChI=1S/C30H28O8/c1-36-21-10-7-19(8-11-21)6-4-2-3-5-17-37-25-15-12-23-28(33)24-18-20(30(34)35)9-14-26(24)38-29(23)22(25)13-16-27(31)32/h4,6-12,14-15,18H,2-3,5,13,16-17H2,1H3,(H,31,32)(H,34,35)/b6-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition constant against binding of [3H]-LTB4 to human neutrophils				J Med Chem 36: 1726-34 (1993) BindingDB Entry DOI: 10.7270/Q2JQ1023
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C33H30O7/c1-2-21-19-26(22-9-4-3-5-10-22)27(34)20-30(21)39-18-8-17-38-28-15-13-25-32(37)23-11-6-7-12-29(23)40-33(25)24(28)14-16-31(35)36/h3-7,9-13,15,19-20,34H,2,8,14,16-18H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C33H30O7/c1-2-21-19-26(22-9-4-3-5-10-22)27(34)20-30(21)39-18-8-17-38-28-15-13-25-32(37)23-11-6-7-12-29(23)40-33(25)24(28)14-16-31(35)36/h3-7,9-13,15,19-20,34H,2,8,14,16-18H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029452 (2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCCc1c(Cc2ccccc2C(O)=O)cccc1OCCCOc1cc(O)c(cc1CC)-c1ccc(F)cc1 Show InChI InChI=1S/C34H35FO5/c1-3-9-28-25(20-26-10-5-6-12-29(26)34(37)38)11-7-13-32(28)39-18-8-19-40-33-22-31(36)30(21-23(33)4-2)24-14-16-27(35)17-15-24/h5-7,10-17,21-22,36H,3-4,8-9,18-20H2,1-2H3,(H,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligand				J Med Chem 38: 4411-32 (1995) BindingDB Entry DOI: 10.7270/Q20V8BSQ
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029468 (2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)-c2ccc(F)cc2)cccc1C(=O)c1ccccc1C(O)=O Show InChI InChI=1S/C34H33FO6/c1-3-9-25-26(33(37)27-10-5-6-11-28(27)34(38)39)12-7-13-31(25)40-18-8-19-41-32-21-30(36)29(20-22(32)4-2)23-14-16-24(35)17-15-23/h5-7,10-17,20-21,36H,3-4,8-9,18-19H2,1-2H3,(H,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligand				J Med Chem 38: 4411-32 (1995) BindingDB Entry DOI: 10.7270/Q20V8BSQ
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029460 (3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C33H29FO7/c1-2-20-18-26(21-8-10-22(34)11-9-21)27(35)19-30(20)40-17-5-16-39-28-14-12-25-32(38)23-6-3-4-7-29(23)41-33(25)24(28)13-15-31(36)37/h3-4,6-12,14,18-19,35H,2,5,13,15-17H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029467 (2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)-c2ccc(F)cc2)cccc1S(=O)(=O)c1ccccc1C(O)=O Show InChI InChI=1S/C33H33FO7S/c1-3-9-25-29(11-7-13-31(25)42(38,39)32-12-6-5-10-26(32)33(36)37)40-18-8-19-41-30-21-28(35)27(20-22(30)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligand				J Med Chem 38: 4411-32 (1995) BindingDB Entry DOI: 10.7270/Q20V8BSQ
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029460 (3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C33H29FO7/c1-2-20-18-26(21-8-10-22(34)11-9-21)27(35)19-30(20)40-17-5-16-39-28-14-12-25-32(38)23-6-3-4-7-29(23)41-33(25)24(28)13-15-31(36)37/h3-4,6-12,14,18-19,35H,2,5,13,15-17H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50029484 (2-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCCc1c(OCCCOc2cc(O)c(cc2CC)-c2ccc(F)cc2)cccc1Sc1ccccc1C(O)=O Show InChI InChI=1S/C33H33FO5S/c1-3-9-25-29(11-7-13-31(25)40-32-12-6-5-10-26(32)33(36)37)38-18-8-19-39-30-21-28(35)27(20-22(30)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards LTB4 receptor guinea pig spleen cells using [3H]-LTB4 as radioligand				J Med Chem 38: 4411-32 (1995) BindingDB Entry DOI: 10.7270/Q20V8BSQ
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50132988 (4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quino...) Show SMILES Brc1cccc(n1)-c1n[nH]cc1-c1ccnc2ccccc12 Show InChI InChI=1S/C17H11BrN4/c18-16-7-3-6-15(21-16)17-13(10-20-22-17)11-8-9-19-14-5-2-1-4-12(11)14/h1-10H,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)				J Med Chem 46: 3953-6 (2003) Article DOI: 10.1021/jm0205705 BindingDB Entry DOI: 10.7270/Q2RV0N38
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50029464 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C34H29FO9/c1-2-19-16-25(20-4-7-22(35)8-5-20)27(36)18-30(19)43-15-3-14-42-28-12-9-24-32(39)26-17-21(34(40)41)6-11-29(26)44-33(24)23(28)10-13-31(37)38/h4-9,11-12,16-18,36H,2-3,10,13-15H2,1H3,(H,37,38)(H,40,41)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of LTB4-induced up-regulation of human neutrophil CD11b/CD18 integrin				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518497 (US11124509, Compound 68) Show SMILES Fc1cc(F)cc(NCc2nc(-c3ccn(n3)C3CC3)c([nH]2)-c2ccc3nccnc3c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50029460 (3-{3-[3-(5-Ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yl...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C33H29FO7/c1-2-20-18-26(21-8-10-22(34)11-9-21)27(35)19-30(20)40-17-5-16-39-28-14-12-25-32(38)23-6-3-4-7-29(23)41-33(25)24(28)13-15-31(36)37/h3-4,6-12,14,18-19,35H,2,5,13,15-17H2,1H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to guinea pig lung membranes expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50001611 ((E)-3-{3-(2-Carboxy-ethyl)-4-[6-(4-methoxy-phenyl)...) Show SMILES COc1ccc(\C=C\CCCCOc2ccc(cc2CCC(O)=O)C(=O)c2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C30H30O7/c1-36-26-14-10-21(11-15-26)7-4-2-3-5-18-37-27-16-12-24(19-22(27)13-17-28(31)32)29(33)23-8-6-9-25(20-23)30(34)35/h4,6-12,14-16,19-20H,2-3,5,13,17-18H2,1H3,(H,31,32)(H,34,35)/b7-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-LTB4 to receptor on nonradioactive LTB4				J Med Chem 36: 1726-34 (1993) BindingDB Entry DOI: 10.7270/Q2JQ1023
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50132988 (4-[3-(6-Bromo-pyridin-2-yl)-1H-pyrazol-4-yl]-quino...) Show SMILES Brc1cccc(n1)-c1n[nH]cc1-c1ccnc2ccccc12 Show InChI InChI=1S/C17H11BrN4/c18-16-7-3-6-15(21-16)17-13(10-20-22-17)11-8-9-19-14-5-2-1-4-12(11)14/h1-10H,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)				J Med Chem 46: 3953-6 (2003) Article DOI: 10.1021/jm0205705 BindingDB Entry DOI: 10.7270/Q2RV0N38
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50132989 (4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...) Show SMILES Cc1cccc(n1)-c1n[nH]cc1-c1ccnc2ccccc12 Show InChI InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H,1H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)				J Med Chem 46: 3953-6 (2003) Article DOI: 10.1021/jm0205705 BindingDB Entry DOI: 10.7270/Q2RV0N38
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161301 (2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3CCCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C30H29N3O6S/c1-19-26(29(35)30(31)36)27-24(39-18-25(34)32-40(37,38)22-13-6-3-7-14-22)16-21-12-8-9-15-23(21)28(27)33(19)17-20-10-4-2-5-11-20/h2-7,10-11,13-14,16H,8-9,12,15,17-18H2,1H3,(H2,31,36)(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518501 (US11124509, Compound 69) Show SMILES Fc1cc(F)cc(NCc2nc(-c3ccn(n3)C3CC3)c([nH]2)-c2ccc3ncnn3c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50029477 (5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-2-hydroxy-biphen...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccc(cc3c2=O)C(O)=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C34H30O9/c1-2-20-17-25(21-7-4-3-5-8-21)27(35)19-30(20)42-16-6-15-41-28-13-10-24-32(38)26-18-22(34(39)40)9-12-29(26)43-33(24)23(28)11-14-31(36)37/h3-5,7-10,12-13,17-19,35H,2,6,11,14-16H2,1H3,(H,36,37)(H,39,40)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161305 ((3-Aminooxalyl-1-cyclohexylmethyl-2-methyl-2,3-dih...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3ccccc3c2n1CC1CCCCC1 Show InChI InChI=1S/C24H26N2O5/c1-14-20(23(29)24(25)30)21-18(31-13-19(27)28)11-16-9-5-6-10-17(16)22(21)26(14)12-15-7-3-2-4-8-15/h5-6,9-11,15H,2-4,7-8,12-13H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518482 (US11124509, Compound 55) Show SMILES Cn1ccc(n1)-c1nc[nH]c1-c1ccc2ncsc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.71	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1/2 (Homo sapiens (Human))	BDBM50029448 (3-{3-[3-(5-Ethyl-2-hydroxy-biphenyl-4-yloxy)-propo...) Show SMILES CCc1cc(c(O)cc1OCCCOc1ccc2c(oc3ccccc3c2=O)c1CCC(O)=O)-c1ccccc1 Show InChI InChI=1S/C33H30O7/c1-2-21-19-26(22-9-4-3-5-10-22)27(34)20-30(21)39-18-8-17-38-28-15-13-25-32(37)23-11-6-7-12-29(23)40-33(25)24(28)14-16-31(35)36/h3-7,9-13,15,19-20,34H,2,8,14,16-18H2,1H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Tested for inhibition of specific binding of [3H]-LTB4 to human neutrophil expressing LTB4 receptor				J Med Chem 36: 3982-4 (1994) BindingDB Entry DOI: 10.7270/Q2H1313H
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518474 (US11124509, Compound 46) Show SMILES FC(F)n1ccc(n1)-c1nc(CNc2cccc(F)c2)[nH]c1-c1ccc2nccnc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518465 (US11124509, Compound 37) Show SMILES Cn1ccc(n1)-c1nc([nH]c1-c1ccc2ncsc2c1)-c1ccc(cc1)C(N)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161293 ((3-Aminooxalyl-1-benzyl-2-methyl-1,6,7,8-tetrahydr...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C23H22N2O5/c1-13-19(22(28)23(24)29)20-17(30-12-18(26)27)10-15-8-5-9-16(15)21(20)25(13)11-14-6-3-2-4-7-14/h2-4,6-7,10H,5,8-9,11-12H2,1H3,(H2,24,29)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 1 (Homo sapiens (Human))	BDBM50045092 (5-(2-Carboxy-ethyl)-6-[(E)-6-(4-methoxy-phenyl)-he...) Show SMILES COc1ccc(\C=C\CCCCOc2ccc3c(oc4ccc(cc4c3=O)C(O)=O)c2CCC(O)=O)cc1 Show InChI InChI=1S/C30H28O8/c1-36-21-10-7-19(8-11-21)6-4-2-3-5-17-37-25-15-12-23-28(33)24-18-20(30(34)35)9-14-26(24)38-29(23)22(25)13-16-27(31)32/h4,6-12,14-15,18H,2-3,5,13,16-17H2,1H3,(H,31,32)(H,34,35)/b6-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of specific binding of LTB4 ( 0.1 nM) to receptors on intact human neutrophils				J Med Chem 36: 1726-34 (1993) BindingDB Entry DOI: 10.7270/Q2JQ1023
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518475 (US11124509, Compound 47) Show SMILES FC(F)n1ccc(n1)-c1nc(CNc2cccc(c2)C#N)[nH]c1-c1ccc2nccnc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518472 (US11124509, Compound 44) Show SMILES Cc1nc(-c2ccn(C)n2)c([nH]1)-c1ccc2ncsc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50132986 (4-(3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)q...) Show SMILES FC(F)(F)c1cccc(c1)-c1n[nH]cc1-c1ccnc2ccccc12 Show InChI InChI=1S/C19H12F3N3/c20-19(21,22)13-5-3-4-12(10-13)18-16(11-24-25-18)14-8-9-23-17-7-2-1-6-15(14)17/h1-11H,(H,24,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Mitogen-activated protein kinase p38				J Med Chem 46: 3953-6 (2003) Article DOI: 10.1021/jm0205705 BindingDB Entry DOI: 10.7270/Q2RV0N38
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161299 ((3-Aminooxalyl-1-benzyl-2-ethyl-1,6,7,8-tetrahydro...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C24H24N2O5/c1-2-17-20(23(29)24(25)30)21-18(31-13-19(27)28)11-15-9-6-10-16(15)22(21)26(17)12-14-7-4-3-5-8-14/h3-5,7-8,11H,2,6,9-10,12-13H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161301 (2-[4-(2-Benzenesulfonylamino-2-oxo-ethoxy)-1-benzy...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3CCCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C30H29N3O6S/c1-19-26(29(35)30(31)36)27-24(39-18-25(34)32-40(37,38)22-13-6-3-7-14-22)16-21-12-8-9-15-23(21)28(27)33(19)17-20-10-4-2-5-11-20/h2-7,10-11,13-14,16H,8-9,12,15,17-18H2,1H3,(H2,31,36)(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50055366 ((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1 Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50132989 (4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...) Show SMILES Cc1cccc(n1)-c1n[nH]cc1-c1ccnc2ccccc12 Show InChI InChI=1S/C18H14N4/c1-12-5-4-8-17(21-12)18-15(11-20-22-18)13-9-10-19-16-7-3-2-6-14(13)16/h2-11H,1H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)				J Med Chem 46: 3953-6 (2003) Article DOI: 10.1021/jm0205705 BindingDB Entry DOI: 10.7270/Q2RV0N38
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM518488 (US11124509, Compound 61) Show SMILES NC(=O)c1ccc(cc1)-c1nc(-c2ccn(n2)C(F)F)c([nH]1)-c1ccc2ncsc2c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.55	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Exemplified compounds were screened in 1% DMSO (final concentration) by 3-fold serial dilutions from 10,000 nM to 0.316 nM to produce an IC50 or at s...				Citation and Details BindingDB Entry DOI: 10.7270/Q2474F1M
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161308 (CHEMBL179118 | [3-Aminooxalyl-1-(2-fluoro-benzyl)-...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1ccccc1F Show InChI InChI=1S/C23H21FN2O5/c1-12-19(22(29)23(25)30)20-17(31-11-18(27)28)9-13-6-4-7-15(13)21(20)26(12)10-14-5-2-3-8-16(14)24/h2-3,5,8-9H,4,6-7,10-11H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161298 ((3-Aminooxalyl-1-benzyl-2-methyl-2,3,6,7,8,9-hexah...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C24H24N2O5/c1-14-20(23(29)24(25)30)21-18(31-13-19(27)28)11-16-9-5-6-10-17(16)22(21)26(14)12-15-7-3-2-4-8-15/h2-4,7-8,11H,5-6,9-10,12-13H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161293 ((3-Aminooxalyl-1-benzyl-2-methyl-1,6,7,8-tetrahydr...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C23H22N2O5/c1-13-19(22(28)23(24)29)20-17(30-12-18(26)27)10-15-8-5-9-16(15)21(20)25(13)11-14-6-3-2-4-7-14/h2-4,6-7,10H,5,8-9,11-12H2,1H3,(H2,24,29)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161294 (CHEMBL179966 | [3-Aminooxalyl-1-(3-fluoro-benzyl)-...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1cccc(F)c1 Show InChI InChI=1S/C23H21FN2O5/c1-12-19(22(29)23(25)30)20-17(31-11-18(27)28)9-14-5-3-7-16(14)21(20)26(12)10-13-4-2-6-15(24)8-13/h2,4,6,8-9H,3,5,7,10-11H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161296 ((3-Aminooxalyl-1-benzyl-2-ethyl-2,3,6,7,8,9-hexahy...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C25H26N2O5/c1-2-18-21(24(30)25(26)31)22-19(32-14-20(28)29)12-16-10-6-7-11-17(16)23(22)27(18)13-15-8-4-3-5-9-15/h3-5,8-9,12H,2,6-7,10-11,13-14H2,1H3,(H2,26,31)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161305 ((3-Aminooxalyl-1-cyclohexylmethyl-2-methyl-2,3-dih...) Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3ccccc3c2n1CC1CCCCC1 Show InChI InChI=1S/C24H26N2O5/c1-14-20(23(29)24(25)30)21-18(31-13-19(27)28)11-16-9-5-6-10-17(16)22(21)26(14)12-15-7-3-2-4-8-15/h5-6,9-11,15H,2-4,7-8,12-13H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50161299 ((3-Aminooxalyl-1-benzyl-2-ethyl-1,6,7,8-tetrahydro...) Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cc3CCCc3c2n1Cc1ccccc1 Show InChI InChI=1S/C24H24N2O5/c1-2-17-20(23(29)24(25)30)21-18(31-13-19(27)28)11-15-9-6-10-16(15)22(21)26(17)12-14-7-4-3-5-8-14/h3-5,7-8,11H,2,6,9-10,12-13H2,1H3,(H2,25,30)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
The Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against human nonpancreatic secretory phospholipase A2				J Med Chem 48: 893-6 (2005) Article DOI: 10.1021/jm0401309 BindingDB Entry DOI: 10.7270/Q20001M3
					More data for this Ligand-Target Pair

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