Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50240434![]() (2-[1-(6-Amino-purin-9-yl)-2-oxo-ethoxy]-propenal |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of S-adenosyl homocysteine (SAH) hydrolase . | Bioorg Med Chem Lett 6: 1381-1386 (1996) Article DOI: 10.1016/0960-894X(96)00234-X BindingDB Entry DOI: 10.7270/Q29P31NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28586![]() (1-{3-[(3-chlorophenyl)methoxy]-2-methylphenyl}pipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.600 | -52.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28583![]() (5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 0.660 | -51.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002254![]() (2-(1-Benzyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-et...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28584![]() (1-[3-(benzyloxy)-2-methylphenyl]piperazine | tolyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.30 | -50.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28635![]() (2-methyl-3-(piperidin-4-yl)phenyl naphthalene-1-su...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.5 | -50.4 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002275![]() (1-Benzyl-4-(3-phenyl-propoxy)-piperidine; compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002303![]() (1-Cyclopropylmethyl-4-(3,4-difluoro-phenoxymethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002207![]() (1-Cyclopropylmethyl-4-(4-fluoro-phenoxymethyl)-pip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002292![]() (4-[4-(4-Fluoro-benzyloxymethyl)-piperidin-1-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002209![]() (1-(2,2-Dichloro-1-methyl-cyclopropylmethyl)-4-(4-f...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002235![]() (1-Benzyl-4-(4-trifluoromethyl-phenoxymethyl)-piper...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002232![]() (1-Benzyl-4-(4-phenyl-butoxymethyl)-piperidine; hyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002219![]() (1-Benzyl-4-cyclopropoxymethyl-piperidine; compound...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002252![]() (1-Benzyl-4-(4-fluoro-phenoxymethyl)-piperidine; hy...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002241![]() (1-(4-Chloro-benzyl)-4-(4-fluoro-benzyloxymethyl)-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002190![]() (1-Benzyl-4-(4-fluoro-benzyloxymethyl)-piperidine; ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002229![]() (1-Benzyl-4-cyclohexyloxymethyl-piperidine; hydroch...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28620![]() (2-[1-(3-chlorophenyl)-2,2,2-trifluoroethoxy]-3-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.40 | -49.2 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28594![]() (4-{3-[(3-fluorophenyl)methoxy]-2-methylphenyl}pipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.5 | -48.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28636![]() (2-methyl-3-(piperidin-4-yl)phenyl naphthalene-2-su...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.70 | -48.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28603![]() (4-{3-[(1S)-1-(3-chlorophenyl)ethoxy]-2-methylpheny...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.80 | -48.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002280![]() (1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-et...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002250![]() (1-(4-Fluoro-phenyl)-2-[1-(4-trifluoromethyl-benzyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002187![]() (1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-et...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002272![]() (1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-phenoxymethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002284![]() (1-Benzyl-4-(4-methoxy-phenoxymethyl)-piperidine | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002263![]() (1-Cyclohexylmethyl-4-(4-fluoro-benzyloxymethyl)-pi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002197![]() (1-(1-Benzyl-piperidin-4-yl)-3-(4-fluoro-phenyl)-pr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002217![]() (2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(4-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002268![]() (1-Benzyl-4-(3-phenyl-propoxymethyl)-piperidine; co...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28595![]() (4-{3-[(3-chlorophenyl)methoxy]-2-methylphenyl}pipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.30 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosylhomocysteinase (Homo sapiens (Human)) | BDBM50029130![]() (Adenosine dialdehyde | CHEMBL165876) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of S-adenosyl homocysteine (SAH) hydrolase . | Bioorg Med Chem Lett 6: 1381-1386 (1996) Article DOI: 10.1016/0960-894X(96)00234-X BindingDB Entry DOI: 10.7270/Q29P31NC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse)) | BDBM50002288![]() (1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28623![]() (4-[3-(3-chlorophenoxymethyl)-2-methylphenyl]piperi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | 3.5 | -48.3 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002267![]() (1-Benzyl-4-(4-methoxy-benzyloxymethyl)-piperidine;...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse)) | BDBM50002213![]() (1-(4-Fluoro-phenyl)-2-{1-[2-(1H-indol-3-yl)-ethyl]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002189![]() (2-(1-Benzyl-piperidin-4-yl)-1-(4-methoxy-phenyl)-e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50398864![]() (CHEMBL2178164) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research Curated by ChEMBL | Assay Description Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cells | J Med Chem 55: 9208-23 (2012) Article DOI: 10.1021/jm300931y BindingDB Entry DOI: 10.7270/Q20G3M8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002194![]() (4-(4-Fluoro-benzyloxymethyl)-1-phenethyl-piperidin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002222![]() (1-Benzyl-4-benzyloxymethyl-piperidine; hydrochlori...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002260![]() (1-Cyclopropylmethyl-4-(2,4-dichloro-phenoxymethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002256![]() (4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-2-ylmeth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002290![]() (1-Benzyl-4-[2-(4-fluoro-phenoxy)-ethyl]-piperidine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002293![]() (4-(4-Chloro-phenoxymethyl)-1-cyclopropylmethyl-pip...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM28621![]() (3-methyl-4-(piperidin-4-yl)-2-[2,2,2-trifluoro-1-(...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 4.30 | -47.8 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Pfizer | Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo... | Bioorg Med Chem Lett 19: 2409-12 (2009) Article DOI: 10.1016/j.bmcl.2009.03.077 BindingDB Entry DOI: 10.7270/Q24T6GP5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002225![]() (1-Benzyl-4-[2-(4-tert-butyl-benzyloxy)-ethyl]-pipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50398882![]() (CHEMBL2178180) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research Curated by ChEMBL | Assay Description Displacement of [3H]BMS-599240 from BACE1 expressed in HEK293 cells | J Med Chem 55: 9208-23 (2012) Article DOI: 10.1021/jm300931y BindingDB Entry DOI: 10.7270/Q20G3M8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002264![]() (2-(1-Benzyl-piperidin-4-yl)-1-thiophen-2-yl-ethano...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse)) | BDBM50002200![]() (4-(4-Fluoro-phenoxymethyl)-1-(2-methyl-cyclopropyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Du Pont Merck Pharmaceutical Company Curated by ChEMBL | Assay Description In vitro binding affinity for the mouse sigma opioid receptor | J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 2527 total ) | Next | Last >> |