Compile Data Set for Download or QSAR

Found 162 hits with Last Name = 'culp' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076782 (CHEMBL10154 | N-Cyclopropylmethyl-N-ethyl-2,5-dime...) Show SMILES CCN(CC1CC1)c1nc(C)nc(Nc2c(Cl)cc(Cl)cc2Cl)c1C Show InChI InChI=1S/C18H21Cl3N4/c1-4-25(9-12-5-6-12)18-10(2)17(22-11(3)23-18)24-16-14(20)7-13(19)8-15(16)21/h7-8,12H,4-6,9H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074349 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-(1-ethyl-pro...) Show SMILES CCC(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H30BrN3/c1-7-16(8-2)19-12-15(6)23-21(24-19)25(9-3)20-11-10-17(14(4)5)13-18(20)22/h10-14,16H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076765 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1[N+]([O-])=O)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H23BrN4O2/c1-5-26(21-11-10-16(14(2)3)13-18(21)23)22-24-15(4)12-19(25-22)17-8-6-7-9-20(17)27(28)29/h6-14H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076764 ((2-Bromo-4-methylsulfanyl-phenyl)-ethyl-[4-methyl-...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(SC)cc1Br Show InChI InChI=1S/C21H19BrF3N3S/c1-4-28(19-10-9-14(29-3)12-17(19)22)20-26-13(2)11-18(27-20)15-7-5-6-8-16(15)21(23,24)25/h5-12H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50058163 (Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...) Show SMILES CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c1c(C)cc(C)cc1C |(-10.62,2.69,;-9.29,3.46,;-7.95,2.7,;-6.62,3.48,;-5.28,2.71,;-3.95,3.49,;-3.96,5.03,;-5.27,1.17,;-6.6,.4,;-6.6,-1.14,;-7.94,-1.91,;-5.27,-1.91,;-3.92,-1.14,;-2.44,-1.61,;-1.54,-.35,;-2.46,.9,;-1.99,2.37,;-3.93,.41,;-1.96,-3.07,;-2.99,-4.22,;-4.49,-3.91,;-2.5,-5.68,;-.99,-5.99,;-.51,-7.46,;.03,-4.83,;-.46,-3.38,;.56,-2.22,)| Show InChI InChI=1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50058163 (Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...) Show SMILES CCCCN(CC)c1nc(C)nc2n(cc(C)c12)-c1c(C)cc(C)cc1C |(-10.62,2.69,;-9.29,3.46,;-7.95,2.7,;-6.62,3.48,;-5.28,2.71,;-3.95,3.49,;-3.96,5.03,;-5.27,1.17,;-6.6,.4,;-6.6,-1.14,;-7.94,-1.91,;-5.27,-1.91,;-3.92,-1.14,;-2.44,-1.61,;-1.54,-.35,;-2.46,.9,;-1.99,2.37,;-3.93,.41,;-1.96,-3.07,;-2.99,-4.22,;-4.49,-3.91,;-2.5,-5.68,;-.99,-5.99,;-.51,-7.46,;.03,-4.83,;-.46,-3.38,;.56,-2.22,)| Show InChI InChI=1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074354 (CHEMBL168131 | N,N-Diallyl-N'-(2-bromo-4-dimethyla...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)N(C)C Show InChI InChI=1S/C20H27BrN6/c1-7-12-26(13-8-2)19-22-15(4)23-20(24-19)27(9-3)18-11-10-16(25(5)6)14-17(18)21/h7-8,10-11,14H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076754 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C23H23BrF3N3/c1-5-30(21-11-10-16(14(2)3)13-19(21)24)22-28-15(4)12-20(29-22)17-8-6-7-9-18(17)23(25,26)27/h6-14H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074458 (CHEMBL9633 | [3-(2-Bromo-4,6-dimethoxy-phenyl)-5-m...) Show SMILES CCCCN(CC)c1nc(C)nc2n(nnc12)-c1c(Br)cc(OC)cc1OC |(13.26,-.73,;11.93,.04,;10.59,-.73,;9.26,.02,;7.91,-.75,;6.58,.02,;5.24,-.76,;7.92,-2.29,;6.59,-3.06,;6.59,-4.61,;5.24,-5.38,;7.92,-5.38,;9.26,-4.6,;10.73,-5.08,;11.64,-3.83,;10.73,-2.58,;9.26,-3.06,;11.2,-6.55,;12.7,-6.86,;13.73,-5.71,;13.19,-8.31,;12.16,-9.47,;12.63,-10.95,;11.6,-12.09,;10.64,-9.15,;10.17,-7.69,;8.66,-7.37,;7.63,-8.52,)| Show InChI InChI=1S/C19H25BrN6O2/c1-6-8-9-25(7-2)18-16-19(22-12(3)21-18)26(24-23-16)17-14(20)10-13(27-4)11-15(17)28-5/h10-11H,6-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074456 (CHEMBL10504 | SC241 | [3-(2-Bromo-4-isopropyl-phen...) Show SMILES COCCN(CCOC)c1nc(C)nc2n(nnc12)-c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C20H27BrN6O2/c1-13(2)15-6-7-17(16(21)12-15)27-20-18(24-25-27)19(22-14(3)23-20)26(8-10-28-4)9-11-29-5/h6-7,12-13H,8-11H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074332 (CHEMBL167463 | N,N-Diallyl-N'-(2-bromo-4-trifluoro...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(OC(F)(F)F)cc1Br Show InChI InChI=1S/C19H21BrF3N5O/c1-5-10-27(11-6-2)17-24-13(4)25-18(26-17)28(7-3)16-9-8-14(12-15(16)20)29-19(21,22)23/h5-6,8-9,12H,1-2,7,10-11H2,3-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074404 (CHEMBL168844 | N-(2-Bromo-4-isopropyl-phenyl)-N-et...) Show SMILES CCCN(CCC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H32BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h10-11,14-15H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074391 (CHEMBL424555 | N,N-Diallyl-N'-(2-bromo-4-isopropyl...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h7-8,10-11,14-15H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076746 (1-(3-Bromo-4-{ethyl-[4-methyl-6-(2-trifluoromethyl...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)=O Show InChI InChI=1S/C22H19BrF3N3O/c1-4-29(20-10-9-15(14(3)30)12-18(20)23)21-27-13(2)11-19(28-21)16-7-5-6-8-17(16)22(24,25)26/h5-12H,4H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074333 (CHEMBL353877 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...) Show SMILES CCCN(C1CC1)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H31BrN4/c1-6-12-27(18-9-10-18)21-13-16(5)24-22(25-21)26(7-2)20-11-8-17(15(3)4)14-19(20)23/h8,11,13-15,18H,6-7,9-10,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074338 (2-Bromo-N*1*-(4,6-dimethyl-pyrimidin-2-yl)-N*1*-et...) Show SMILES CCN(c1nc(C)cc(C)n1)c1c(Br)cc(cc1OC)N(C)C Show InChI InChI=1S/C17H23BrN4O/c1-7-22(17-19-11(2)8-12(3)20-17)16-14(18)9-13(21(4)5)10-15(16)23-6/h8-10H,7H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074399 (CHEMBL354367 | N-(2-Bromo-4-trifluoromethoxy-pheny...) Show SMILES CCCCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(OC(F)(F)F)cc1Br Show InChI InChI=1S/C19H25BrF3N5O/c1-5-8-11-27(6-2)17-24-13(4)25-18(26-17)28(7-3)16-10-9-14(12-15(16)20)29-19(21,22)23/h9-10,12H,5-8,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074401 (CHEMBL166345 | N-Allyl-N'-(2-bromo-4-isopropyl-phe...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)C1CC1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-6-12-27(17-9-10-17)21-24-15(5)23-20(25-21)26(7-2)19-11-8-16(14(3)4)13-18(19)22/h6,8,11,13-14,17H,1,7,9-10,12H2,2-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074397 (CHEMBL166388 | N-(2-Bromo-4-isopropyl-phenyl)-N'-b...) Show SMILES CCCCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H32BrN5/c1-7-10-13-26(8-2)20-23-16(6)24-21(25-20)27(9-3)19-12-11-17(15(4)5)14-18(19)22/h11-12,14-15H,7-10,13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074384 (CHEMBL167428 | N-Cyclopropylmethyl-N'-(4-dimethyla...) Show SMILES CCCN(CC1CC1)c1nc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C22H31F3N6/c1-6-12-30(14-16-8-9-16)20-26-15(3)27-21(28-20)31(7-2)19-11-10-17(29(4)5)13-18(19)22(23,24)25/h10-11,13,16H,6-9,12,14H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074375 (CHEMBL354395 | N,N-Bis-cyclopropylmethyl-N'-(4-dim...) Show SMILES CCN(c1nc(C)nc(n1)N(CC1CC1)CC1CC1)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C23H31F3N6/c1-5-32(20-11-10-18(30(3)4)12-19(20)23(24,25)26)22-28-15(2)27-21(29-22)31(13-16-6-7-16)14-17-8-9-17/h10-12,16-17H,5-9,13-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074336 (1-{3-Bromo-4-[(4-diethylamino-6-methyl-pyrimidin-2...) Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)=O Show InChI InChI=1S/C19H25BrN4O/c1-6-23(7-2)18-11-13(4)21-19(22-18)24(8-3)17-10-9-15(14(5)25)12-16(17)20/h9-12H,6-8H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074330 (3-({4-[(4-Dimethylamino-2-trifluoromethyl-phenyl)-...) Show SMILES CCCN(CCC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C21H28F3N7/c1-6-12-30(13-8-11-25)19-26-15(3)27-20(28-19)31(7-2)18-10-9-16(29(4)5)14-17(18)21(22,23)24/h9-10,14H,6-8,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076779 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2-...) Show SMILES CCN(c1nc(C)nc(n1)-c1ccccc1C(F)(F)F)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H22BrF3N4/c1-5-30(19-11-10-15(13(2)3)12-18(19)23)21-28-14(4)27-20(29-21)16-8-6-7-9-17(16)22(24,25)26/h6-13H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076768 ((2,4-Dibromo-phenyl)-ethyl-[4-methyl-6-(2-trifluor...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1ccc(Br)cc1Br Show InChI InChI=1S/C20H16Br2F3N3/c1-3-28(18-9-8-13(21)11-16(18)22)19-26-12(2)10-17(27-19)14-6-4-5-7-15(14)20(23,24)25/h4-11H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076747 (2-{2-[(2-Bromo-4-isopropyl-phenyl)-ethyl-amino]-6-...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C#N)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C23H23BrN4/c1-5-28(22-11-10-17(15(2)3)13-20(22)24)23-26-16(4)12-21(27-23)19-9-7-6-8-18(19)14-25/h6-13,15H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074347 ((Butyl-{4-[(4-dimethylamino-2-trifluoromethyl-phen...) Show SMILES CCCCN(CC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C21H28F3N7/c1-6-8-12-30(13-11-25)19-26-15(3)27-20(28-19)31(7-2)18-10-9-16(29(4)5)14-17(18)21(22,23)24/h9-10,14H,6-8,12-13H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074388 (CHEMBL168497 | N-(4-Dimethylamino-2-trifluoromethy...) Show SMILES CCCN(CCC)c1nc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C21H31F3N6/c1-7-12-29(13-8-2)19-25-15(4)26-20(27-19)30(9-3)18-11-10-16(28(5)6)14-17(18)21(22,23)24/h10-11,14H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074339 (CHEMBL424538 | N-(2-Bromo-4-dimethylamino-phenyl)-...) Show SMILES CCN(CC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)N(C)C Show InChI InChI=1S/C18H27BrN6/c1-7-24(8-2)17-20-13(4)21-18(22-17)25(9-3)16-11-10-14(23(5)6)12-15(16)19/h10-12H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074381 (CHEMBL168169 | N-(4-Dimethylamino-2-methyl-phenyl)...) Show SMILES CCCN(CCC)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C Show InChI InChI=1S/C21H34N6/c1-8-13-26(14-9-2)20-22-17(5)23-21(24-20)27(10-3)19-12-11-18(25(6)7)15-16(19)4/h11-12,15H,8-10,13-14H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074335 (3-({4-[(4-Dimethylamino-2-methyl-phenyl)-ethyl-ami...) Show SMILES CCCN(CCC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C Show InChI InChI=1S/C21H31N7/c1-7-13-27(14-9-12-22)20-23-17(4)24-21(25-20)28(8-2)19-11-10-18(26(5)6)15-16(19)3/h10-11,15H,7-9,13-14H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076766 ((2-Bromo-4-isopropyl-phenyl)-ethyl-(4-methyl-6-nap...) Show SMILES CCN(c1nc(C)cc(n1)-c1cccc2ccccc12)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C26H26BrN3/c1-5-30(25-14-13-20(17(2)3)16-23(25)27)26-28-18(4)15-24(29-26)22-12-8-10-19-9-6-7-11-21(19)22/h6-17H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074368 (1-(3-Bromo-4-{[4-(butyl-ethyl-amino)-6-methyl-pyri...) Show SMILES CCCCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)=O Show InChI InChI=1S/C21H29BrN4O/c1-6-9-12-25(7-2)20-13-15(4)23-21(24-20)26(8-3)19-11-10-17(16(5)27)14-18(19)22/h10-11,13-14H,6-9,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074394 (3-(Butyl-{4-[(4-dimethylamino-2-methyl-phenyl)-eth...) Show SMILES CCCCN(CCC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C Show InChI InChI=1S/C22H33N7/c1-7-9-14-28(15-10-13-23)21-24-18(4)25-22(26-21)29(8-2)20-12-11-19(27(5)6)16-17(20)3/h11-12,16H,7-10,14-15H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074407 ((Butyl-{4-[(4-dimethylamino-2-methyl-phenyl)-ethyl...) Show SMILES CCCCN(CC#N)c1nc(C)nc(n1)N(CC)c1ccc(cc1C)N(C)C Show InChI InChI=1S/C21H31N7/c1-7-9-13-27(14-12-22)20-23-17(4)24-21(25-20)28(8-2)19-11-10-18(26(5)6)15-16(19)3/h10-11,15H,7-9,13-14H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076756 ((4-Biphenyl-2-yl-6-methyl-pyrimidin-2-yl)-(2-bromo...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1-c1ccccc1)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C28H28BrN3/c1-5-32(27-16-15-22(19(2)3)18-25(27)29)28-30-20(4)17-26(31-28)24-14-10-9-13-23(24)21-11-7-6-8-12-21/h6-19H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076761 ((2-Bromo-4,6-dimethoxy-phenyl)-ethyl-[4-methyl-6-(...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1c(Br)cc(OC)cc1OC Show InChI InChI=1S/C22H21BrF3N3O2/c1-5-29(20-17(23)11-14(30-3)12-19(20)31-4)21-27-13(2)10-18(28-21)15-8-6-7-9-16(15)22(24,25)26/h6-12H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074366 (CHEMBL10203 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N*...) Show SMILES CCCN(CCC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H33BrN4/c1-7-12-26(13-8-2)21-14-17(6)24-22(25-21)27(9-3)20-11-10-18(16(4)5)15-19(20)23/h10-11,14-16H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074383 (CHEMBL268993 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...) Show SMILES CCCN(CC1CC1)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C23H33BrN4/c1-6-12-27(15-18-8-9-18)22-13-17(5)25-23(26-22)28(7-2)21-11-10-19(16(3)4)14-20(21)24/h10-11,13-14,16,18H,6-9,12,15H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074393 (CHEMBL353973 | N*2*-(2-Bromo-4-iodo-phenyl)-N*2*,N...) Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(I)cc1Br Show InChI InChI=1S/C17H22BrIN4/c1-5-22(6-2)16-10-12(4)20-17(21-16)23(7-3)15-9-8-13(19)11-14(15)18/h8-11H,5-7H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074366 (CHEMBL10203 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N*...) Show SMILES CCCN(CCC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H33BrN4/c1-7-12-26(13-8-2)21-14-17(6)24-22(25-21)27(9-3)20-11-10-18(16(4)5)15-19(20)23/h10-11,14-16H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076751 ((2-Bromo-4,6-dimethoxy-phenyl)-[4-(2-chloro-phenyl...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1Cl)c1c(Br)cc(OC)cc1OC Show InChI InChI=1S/C21H21BrClN3O2/c1-5-26(20-16(22)11-14(27-3)12-19(20)28-4)21-24-13(2)10-18(25-21)15-8-6-7-9-17(15)23/h6-12H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076758 (2-Bromo-N*1*-ethyl-6-methoxy-N*4*,N*4*-dimethyl-N*...) Show SMILES CCN(c1nc(C)cc(n1)-c1ccccc1C(F)(F)F)c1c(Br)cc(cc1OC)N(C)C Show InChI InChI=1S/C23H24BrF3N4O/c1-6-31(21-18(24)12-15(30(3)4)13-20(21)32-5)22-28-14(2)11-19(29-22)16-9-7-8-10-17(16)23(25,26)27/h7-13H,6H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076785 (2,5,6-Trimethyl-4-(2-trifluoromethyl-phenyl)-7-(2,...) Show SMILES Cc1c(C)c2c(nc(C)nc2n1-c1c(C)cc(C)cc1C)-c1ccccc1C(F)(F)F |(10.94,-6.24,;9.41,-6.24,;8.5,-5,;8.98,-3.54,;7.03,-5.47,;5.71,-4.71,;4.36,-5.47,;4.36,-7.01,;3.03,-7.78,;5.68,-7.8,;7.03,-7.01,;8.5,-7.49,;8.99,-8.96,;7.94,-10.1,;6.44,-9.79,;8.42,-11.57,;9.93,-11.89,;10.41,-13.36,;10.96,-10.73,;10.49,-9.27,;11.51,-8.13,;5.68,-3.16,;7.03,-2.38,;7.03,-.82,;5.68,-.05,;4.36,-.84,;4.36,-2.38,;3.03,-3.15,;1.82,-3.85,;1.54,-2.58,;2.78,-4.73,)| Show InChI InChI=1S/C25H24F3N3/c1-13-11-14(2)23(15(3)12-13)31-17(5)16(4)21-22(29-18(6)30-24(21)31)19-9-7-8-10-20(19)25(26,27)28/h7-12H,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Antagonistic activity for Corticotropin releasing factor receptor 1				Bioorg Med Chem Lett 9: 1063-6 (1999) BindingDB Entry DOI: 10.7270/Q21V5D5N
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076775 ((2-Bromo-4-isopropyl-phenyl)-[4-(2,6-dichloro-phen...) Show SMILES CCN(c1nc(C)cc(n1)-c1c(Cl)cccc1Cl)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H22BrCl2N3/c1-5-28(20-10-9-15(13(2)3)12-16(20)23)22-26-14(4)11-19(27-22)21-17(24)7-6-8-18(21)25/h6-13H,5H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074400 (CHEMBL167122 | N-(2-Bromo-4,6-dimethoxy-phenyl)-N,...) Show SMILES CCN(CC)c1nc(C)nc(n1)N(CC)c1c(Br)cc(OC)cc1OC Show InChI InChI=1S/C18H26BrN5O2/c1-7-23(8-2)17-20-12(4)21-18(22-17)24(9-3)16-14(19)10-13(25-5)11-15(16)26-6/h10-11H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074360 (CHEMBL352378 | N*2*-(2-Chloro-4,6-dimethoxy-phenyl...) Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1c(Cl)cc(OC)cc1OC Show InChI InChI=1S/C19H27ClN4O2/c1-7-23(8-2)17-10-13(4)21-19(22-17)24(9-3)18-15(20)11-14(25-5)12-16(18)26-6/h10-12H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074413 (CHEMBL169094 | N*2*-(4-Dimethylamino-2-trifluorome...) Show SMILES CCN(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1C(F)(F)F)N(C)C Show InChI InChI=1S/C20H28F3N5/c1-7-27(8-2)18-12-14(4)24-19(25-18)28(9-3)17-11-10-15(26(5)6)13-16(17)20(21,22)23/h10-13H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074331 (CHEMBL167444 | N*2*-(2-Bromo-4-isopropyl-phenyl)-N...) Show SMILES CCCN(CCOC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C22H33BrN4O/c1-7-11-26(12-13-28-6)21-14-17(5)24-22(25-21)27(8-2)20-10-9-18(16(3)4)15-19(20)23/h9-10,14-16H,7-8,11-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50076753 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-methyl-6-(2,...) Show SMILES CCN(c1nc(C)cc(n1)-c1c(C)cc(C)cc1C)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C25H30BrN3/c1-8-29(23-10-9-20(15(2)3)14-21(23)26)25-27-19(7)13-22(28-25)24-17(5)11-16(4)12-18(24)6/h9-15H,8H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Displacement of [125I]-TYR-ovine CRH from cloned human corticotropin releasing factor receptor 1 expressed in 293 EBNA cells				Bioorg Med Chem Lett 9: 1057-62 (1999) BindingDB Entry DOI: 10.7270/Q25M64WZ
					More data for this Ligand-Target Pair

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