Compile Data Set for Download or QSAR

Found 368 hits with Last Name = 'cowley' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418229 (CHEMBL1760646) Show SMILES COc1ccc(OC(F)(F)F)cc1Cn1c(cc2cc(ccc12)C#N)C(=O)NCC(C)(C)CO Show InChI InChI=1S/C24H24F3N3O4/c1-23(2,14-31)13-29-22(32)20-10-16-8-15(11-28)4-6-19(16)30(20)12-17-9-18(34-24(25,26)27)5-7-21(17)33-3/h4-10,31H,12-14H2,1-3H3,(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418228 (CHEMBL1760645) Show SMILES CC(C)(CO)CNC(=O)c1cc2cc(ccc2n1Cc1cccc(OC(F)(F)F)c1)C#N Show InChI InChI=1S/C23H22F3N3O3/c1-22(2,14-30)13-28-21(31)20-10-17-8-15(11-27)6-7-19(17)29(20)12-16-4-3-5-18(9-16)32-23(24,25)26/h3-10,30H,12-14H2,1-2H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21278 (5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159903 (1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pent...) Show SMILES COc1ccc(Cl)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)C(C)C)c1 Show InChI InChI=1S/C25H32ClN3O3/c1-17(2)23(32-24-16-19(31-3)8-9-20(24)26)12-15-28-13-10-18(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-18,23H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50200597 (1-(1-(3-(5-methoxy-2-methylphenoxy)-4-methylpentyl...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C26H35N3O3/c1-18(2)24(32-25-17-21(31-4)10-9-19(25)3)13-16-28-14-11-20(12-15-28)29-23-8-6-5-7-22(23)27-26(29)30/h5-10,17-18,20,24H,11-16H2,1-4H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418210 (CHEMBL1760664) Show SMILES Cc1ccc(cc1Cn1c(cc2cc(ccc12)C#N)C(=O)NCCC(C)(C)O)C(F)(F)F Show InChI InChI=1S/C24H24F3N3O2/c1-15-4-6-19(24(25,26)27)11-18(15)14-30-20-7-5-16(13-28)10-17(20)12-21(30)22(31)29-9-8-23(2,3)32/h4-7,10-12,32H,8-9,14H2,1-3H3,(H,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418212 (CHEMBL1760663) Show SMILES CC(C)(O)CCNC(=O)c1cc2cc(ccc2n1Cc1cccc(OC(F)(F)F)c1)C#N Show InChI InChI=1S/C23H22F3N3O3/c1-22(2,31)8-9-28-21(30)20-12-17-10-15(13-27)6-7-19(17)29(20)14-16-4-3-5-18(11-16)32-23(24,25)26/h3-7,10-12,31H,8-9,14H2,1-2H3,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418213 (CHEMBL1760661) Show SMILES COc1ccc(OC(F)(F)F)cc1Cn1c(cc2cc(ccc12)C#N)C(=O)NCC(C)(C)O Show InChI InChI=1S/C23H22F3N3O4/c1-22(2,31)13-28-21(30)19-10-15-8-14(11-27)4-6-18(15)29(19)12-16-9-17(33-23(24,25)26)5-7-20(16)32-3/h4-10,31H,12-13H2,1-3H3,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418211 (CHEMBL1760662) Show SMILES COc1ccc(cc1Cn1c(cc2cc(ccc12)C#N)C(=O)NCC(C)(C)O)C(F)(F)F Show InChI InChI=1S/C23H22F3N3O3/c1-22(2,31)13-28-21(30)19-10-15-8-14(11-27)4-6-18(15)29(19)12-16-9-17(23(24,25)26)5-7-20(16)32-3/h4-10,31H,12-13H2,1-3H3,(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159902 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-phenyl-propy...) Show SMILES Cc1ccc(Cl)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)c2ccccc2)c1 Show InChI InChI=1S/C28H30ClN3O2/c1-20-11-12-23(29)27(19-20)34-26(21-7-3-2-4-8-21)15-18-31-16-13-22(14-17-31)32-25-10-6-5-9-24(25)30-28(32)33/h2-12,19,22,26H,13-18H2,1H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159897 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159921 (1-{1-[3-(2,5-Dimethyl-phenoxy)-4-methyl-pentyl]-pi...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1C Show InChI InChI=1S/C26H35N3O2/c1-18(2)24(31-25-17-19(3)9-10-20(25)4)13-16-28-14-11-21(12-15-28)29-23-8-6-5-7-22(23)27-26(29)30/h5-10,17-18,21,24H,11-16H2,1-4H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159897 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159904 (1-(1-{2-[1-(2-Chloro-5-methyl-phenoxy)-cyclohexyl]...) Show SMILES Cc1ccc(Cl)c(OC2(CCCCC2)C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c1 Show InChI InChI=1S/C27H34ClN3O3/c1-19-9-10-21(28)24(17-19)34-27(13-5-2-6-14-27)25(32)18-30-15-11-20(12-16-30)31-23-8-4-3-7-22(23)29-26(31)33/h3-4,7-10,17,20,25,32H,2,5-6,11-16,18H2,1H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159900 (1-{1-[3-(5-Amino-2-methyl-phenoxy)-4-methyl-pentyl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(N)ccc1C Show InChI InChI=1S/C25H34N4O2/c1-17(2)23(31-24-16-19(26)9-8-18(24)3)12-15-28-13-10-20(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,20,23H,10-15,26H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159902 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-phenyl-propy...) Show SMILES Cc1ccc(Cl)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)c2ccccc2)c1 Show InChI InChI=1S/C28H30ClN3O2/c1-20-11-12-23(29)27(19-20)34-26(21-7-3-2-4-8-21)15-18-31-16-13-22(14-17-31)32-25-10-6-5-9-24(25)30-28(32)33/h2-12,19,22,26H,13-18H2,1H3,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159915 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexy...) Show SMILES CCCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C25H32ClN3O3/c1-3-6-23(32-24-15-17(2)9-10-19(24)26)22(30)16-28-13-11-18(12-14-28)29-21-8-5-4-7-20(21)27-25(29)31/h4-5,7-10,15,18,22-23,30H,3,6,11-14,16H2,1-2H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159913 (1-{1-[3-(2-Isopropyl-phenoxy)-4-methyl-pentyl]-pip...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccccc1C(C)C Show InChI InChI=1S/C27H37N3O2/c1-19(2)22-9-5-8-12-26(22)32-25(20(3)4)15-18-29-16-13-21(14-17-29)30-24-11-7-6-10-23(24)28-27(30)31/h5-12,19-21,25H,13-18H2,1-4H3,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159916 (1-[1-(4-Methyl-3-o-tolyloxy-pentyl)-piperidin-4-yl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccccc1C Show InChI InChI=1S/C25H33N3O2/c1-18(2)23(30-24-11-7-4-8-19(24)3)14-17-27-15-12-20(13-16-27)28-22-10-6-5-9-21(22)26-25(28)29/h4-11,18,20,23H,12-17H2,1-3H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159905 (1-{1-[3-(2-Ethyl-phenoxy)-4-methyl-pentyl]-piperid...) Show SMILES CCc1ccccc1OC(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)C(C)C Show InChI InChI=1S/C26H35N3O2/c1-4-20-9-5-8-12-25(20)31-24(19(2)3)15-18-28-16-13-21(14-17-28)29-23-11-7-6-10-22(23)27-26(29)30/h5-12,19,21,24H,4,13-18H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159922 (1-{1-[4-Methyl-3-(2-trifluoromethyl-phenoxy)-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C25H30F3N3O2/c1-17(2)22(33-23-10-6-3-7-19(23)25(26,27)28)13-16-30-14-11-18(12-15-30)31-21-9-5-4-8-20(21)29-24(31)32/h3-10,17-18,22H,11-16H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159922 (1-{1-[4-Methyl-3-(2-trifluoromethyl-phenoxy)-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccccc1C(F)(F)F Show InChI InChI=1S/C25H30F3N3O2/c1-17(2)22(33-23-10-6-3-7-19(23)25(26,27)28)13-16-30-14-11-18(12-15-30)31-21-9-5-4-8-20(21)29-24(31)32/h3-10,17-18,22H,11-16H2,1-2H3,(H,29,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159917 (1-{1-[3-(2-Fluoro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1F Show InChI InChI=1S/C25H32FN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159915 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexy...) Show SMILES CCCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C25H32ClN3O3/c1-3-6-23(32-24-15-17(2)9-10-19(24)26)22(30)16-28-13-11-18(12-14-28)29-21-8-5-4-7-20(21)27-25(29)31/h4-5,7-10,15,18,22-23,30H,3,6,11-14,16H2,1-2H3,(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159909 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-5-me...) Show SMILES CC(C)CC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C26H34ClN3O3/c1-17(2)14-25(33-24-15-18(3)8-9-20(24)27)23(31)16-29-12-10-19(11-13-29)30-22-7-5-4-6-21(22)28-26(30)32/h4-9,15,17,19,23,25,31H,10-14,16H2,1-3H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159923 (1-{1-[3-(4-Fluoro-2-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccc(F)cc1C Show InChI InChI=1S/C25H32FN3O2/c1-17(2)23(31-24-9-8-19(26)16-18(24)3)12-15-28-13-10-20(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,20,23H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159905 (1-{1-[3-(2-Ethyl-phenoxy)-4-methyl-pentyl]-piperid...) Show SMILES CCc1ccccc1OC(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)C(C)C Show InChI InChI=1S/C26H35N3O2/c1-4-20-9-5-8-12-25(20)31-24(19(2)3)15-18-28-16-13-21(14-17-28)29-23-11-7-6-10-22(23)27-26(29)30/h5-12,19,21,24H,4,13-18H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159923 (1-{1-[3-(4-Fluoro-2-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccc(F)cc1C Show InChI InChI=1S/C25H32FN3O2/c1-17(2)23(31-24-9-8-19(26)16-18(24)3)12-15-28-13-10-20(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,20,23H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159918 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-3-ph...) Show SMILES Cc1ccc(Cl)c(OC(C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c2ccccc2)c1 Show InChI InChI=1S/C28H30ClN3O3/c1-19-11-12-22(29)26(17-19)35-27(20-7-3-2-4-8-20)25(33)18-31-15-13-21(14-16-31)32-24-10-6-5-9-23(24)30-28(32)34/h2-12,17,21,25,27,33H,13-16,18H2,1H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159918 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-3-ph...) Show SMILES Cc1ccc(Cl)c(OC(C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c2ccccc2)c1 Show InChI InChI=1S/C28H30ClN3O3/c1-19-11-12-22(29)26(17-19)35-27(20-7-3-2-4-8-20)25(33)18-31-15-13-21(14-16-31)32-24-10-6-5-9-23(24)30-28(32)34/h2-12,17,21,25,27,33H,13-16,18H2,1H3,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159914 (1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[n-]c1=[OH+])Oc1cc(C)ccc1[N+]([O-])=O Show InChI InChI=1S/C25H32N4O4/c1-17(2)23(33-24-16-18(3)8-9-22(24)29(31)32)12-15-27-13-10-19(11-14-27)28-21-7-5-4-6-20(21)26-25(28)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159916 (1-[1-(4-Methyl-3-o-tolyloxy-pentyl)-piperidin-4-yl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccccc1C Show InChI InChI=1S/C25H33N3O2/c1-18(2)23(30-24-11-7-4-8-19(24)3)14-17-27-15-12-20(13-16-27)28-22-10-6-5-9-21(22)26-25(28)29/h4-11,18,20,23H,12-17H2,1-3H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159924 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-pent...) Show SMILES CCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30ClN3O3/c1-3-22(31-23-14-16(2)8-9-18(23)25)21(29)15-27-12-10-17(11-13-27)28-20-7-5-4-6-19(20)26-24(28)30/h4-9,14,17,21-22,29H,3,10-13,15H2,1-2H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159900 (1-{1-[3-(5-Amino-2-methyl-phenoxy)-4-methyl-pentyl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(N)ccc1C Show InChI InChI=1S/C25H34N4O2/c1-17(2)23(31-24-16-19(26)9-8-18(24)3)12-15-28-13-10-20(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,20,23H,10-15,26H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159907 (1-{1-[3-(4-Fluoro-3-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccc(F)c(C)c1 Show InChI InChI=1S/C25H32FN3O2/c1-17(2)24(31-20-8-9-21(26)18(3)16-20)12-15-28-13-10-19(11-14-28)29-23-7-5-4-6-22(23)27-25(29)30/h4-9,16-17,19,24H,10-15H2,1-3H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159906 (1-{1-[3-(2-Chloro-5-fluoro-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(F)ccc1Cl Show InChI InChI=1S/C24H29ClFN3O2/c1-16(2)22(31-23-15-17(26)7-8-19(23)25)11-14-28-12-9-18(10-13-28)29-21-6-4-3-5-20(21)27-24(29)30/h3-8,15-16,18,22H,9-14H2,1-2H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159904 (1-(1-{2-[1-(2-Chloro-5-methyl-phenoxy)-cyclohexyl]...) Show SMILES Cc1ccc(Cl)c(OC2(CCCCC2)C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c1 Show InChI InChI=1S/C27H34ClN3O3/c1-19-9-10-21(28)24(17-19)34-27(13-5-2-6-14-27)25(32)18-30-15-11-20(12-16-30)31-23-8-4-3-7-22(23)29-26(31)33/h3-4,7-10,17,20,25,32H,2,5-6,11-16,18H2,1H3,(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159903 (1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pent...) Show SMILES COc1ccc(Cl)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)C(C)C)c1 Show InChI InChI=1S/C25H32ClN3O3/c1-17(2)23(32-24-16-19(31-3)8-9-20(24)26)12-15-28-13-10-18(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-18,23H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50200597 (1-(1-(3-(5-methoxy-2-methylphenoxy)-4-methylpentyl...) Show SMILES COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)C(C)C)c1 |w:9.8| Show InChI InChI=1S/C26H35N3O3/c1-18(2)24(32-25-17-21(31-4)10-9-19(25)3)13-16-28-14-11-20(12-15-28)29-23-8-6-5-7-22(23)27-26(29)30/h5-10,17-18,20,24H,11-16H2,1-4H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159924 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-pent...) Show SMILES CCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H30ClN3O3/c1-3-22(31-23-14-16(2)8-9-18(23)25)21(29)15-27-12-10-17(11-13-27)28-20-7-5-4-6-19(20)26-24(28)30/h4-9,14,17,21-22,29H,3,10-13,15H2,1-2H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159914 (1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[n-]c1=[OH+])Oc1cc(C)ccc1[N+]([O-])=O Show InChI InChI=1S/C25H32N4O4/c1-17(2)23(33-24-16-18(3)8-9-22(24)29(31)32)12-15-27-13-10-19(11-14-27)28-21-7-5-4-6-20(21)26-25(28)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159897 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159921 (1-{1-[3-(2,5-Dimethyl-phenoxy)-4-methyl-pentyl]-pi...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1C Show InChI InChI=1S/C26H35N3O2/c1-18(2)24(31-25-17-19(3)9-10-20(25)4)13-16-28-14-11-21(12-15-28)29-23-8-6-5-7-22(23)27-26(29)30/h5-10,17-18,21,24H,11-16H2,1-4H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159897 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1Cl Show InChI InChI=1S/C25H32ClN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159917 (1-{1-[3-(2-Fluoro-5-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1cc(C)ccc1F Show InChI InChI=1S/C25H32FN3O2/c1-17(2)23(31-24-16-18(3)8-9-20(24)26)12-15-28-13-10-19(11-14-28)29-22-7-5-4-6-21(22)27-25(29)30/h4-9,16-17,19,23H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159919 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-4-me...) Show SMILES CC(C)C(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C25H32ClN3O3/c1-16(2)24(32-23-14-17(3)8-9-19(23)26)22(30)15-28-12-10-18(11-13-28)29-21-7-5-4-6-20(21)27-25(29)31/h4-9,14,16,18,22,24,30H,10-13,15H2,1-3H3,(H,27,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159927 (1-(1-{2-[1-(2-Chloro-5-methyl-phenoxy)-cyclohexyl]...) Show SMILES CN(C)C(CN1CCC(CC1)n1c2ccccc2[nH]c1=O)C1(CCCCC1)Oc1cc(C)ccc1Cl Show InChI InChI=1S/C29H39ClN4O2/c1-21-11-12-23(30)26(19-21)36-29(15-7-4-8-16-29)27(32(2)3)20-33-17-13-22(14-18-33)34-25-10-6-5-9-24(25)31-28(34)35/h5-6,9-12,19,22,27H,4,7-8,13-18,20H2,1-3H3,(H,31,35)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159907 (1-{1-[3-(4-Fluoro-3-methyl-phenoxy)-4-methyl-penty...) Show SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)Oc1ccc(F)c(C)c1 Show InChI InChI=1S/C25H32FN3O2/c1-17(2)24(31-20-8-9-21(26)18(3)16-20)12-15-28-13-10-19(11-14-28)29-23-7-5-4-6-22(23)27-25(29)30/h4-9,16-17,19,24H,10-15H2,1-3H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50159899 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-cyclohexyl-2...) Show SMILES Cc1ccc(Cl)c(OC(C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)C2CCCCC2)c1 Show InChI InChI=1S/C28H36ClN3O3/c1-19-11-12-22(29)26(17-19)35-27(20-7-3-2-4-8-20)25(33)18-31-15-13-21(14-16-31)32-24-10-6-5-9-23(24)30-28(32)34/h5-6,9-12,17,20-21,25,27,33H,2-4,7-8,13-16,18H2,1H3,(H,30,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50159919 (1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-4-me...) Show SMILES CC(C)C(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C25H32ClN3O3/c1-16(2)24(32-23-14-17(3)8-9-19(23)26)22(30)15-28-12-10-18(11-13-28)29-21-7-5-4-6-20(21)27-25(29)31/h4-9,14,16,18,22,24,30H,10-13,15H2,1-3H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd Curated by ChEMBL					Assay Description Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...				Bioorg Med Chem Lett 15: 589-93 (2005) Article DOI: 10.1016/j.bmcl.2004.11.049 BindingDB Entry DOI: 10.7270/Q2K35T50
					More data for this Ligand-Target Pair

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