Compile Data Set for Download or QSAR

Found 487 hits with Last Name = 'korfmacher' and Initial = 'wa'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (GUINEA PIG)	BDBM50325449 (1-(2-(piperidin-1-yl)ethyl)-3-(1-(1-(pyridin-4-ylm...) Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2n(CCN2CCCCC2)c1=O Show InChI InChI=1S/C31H42N6O2/c38-30(26-10-18-34(19-11-26)24-25-8-14-32-15-9-25)35-20-12-27(13-21-35)37-29-7-3-2-6-28(29)36(31(37)39)23-22-33-16-4-1-5-17-33/h2-3,6-9,14-15,26-27H,1,4-5,10-13,16-24H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325466 (1-(3-(dimethylamino)propyl)-3-(1-(1-(pyridin-4-ylm...) Show SMILES CN(C)CCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C29H40N6O2/c1-31(2)16-5-17-34-26-6-3-4-7-27(26)35(29(34)37)25-12-20-33(21-13-25)28(36)24-10-18-32(19-11-24)22-23-8-14-30-15-9-23/h3-4,6-9,14-15,24-25H,5,10-13,16-22H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325465 (1-benzyl-3-(1-(1-(pyridin-4-ylmethyl)piperidine-4-...) Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2n(Cc2ccccc2)c1=O Show InChI InChI=1S/C31H35N5O2/c37-30(26-12-18-33(19-13-26)22-25-10-16-32-17-11-25)34-20-14-27(15-21-34)36-29-9-5-4-8-28(29)35(31(36)38)23-24-6-2-1-3-7-24/h1-11,16-17,26-27H,12-15,18-23H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325450 (1-(2-(dimethylamino)ethyl)-3-(1-(1-(pyridin-4-ylme...) Show SMILES CN(C)CCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C28H38N6O2/c1-30(2)19-20-33-25-5-3-4-6-26(25)34(28(33)36)24-11-17-32(18-12-24)27(35)23-9-15-31(16-10-23)21-22-7-13-29-14-8-22/h3-8,13-14,23-24H,9-12,15-21H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325460 (1-(4-methoxybenzyl)-3-(1-(1-(pyridin-4-ylmethyl)pi...) Show SMILES COc1ccc(Cn2c3ccccc3n(C3CCN(CC3)C(=O)C3CCN(Cc4ccncc4)CC3)c2=O)cc1 Show InChI InChI=1S/C32H37N5O3/c1-40-28-8-6-24(7-9-28)23-36-29-4-2-3-5-30(29)37(32(36)39)27-14-20-35(21-15-27)31(38)26-12-18-34(19-13-26)22-25-10-16-33-17-11-25/h2-11,16-17,26-27H,12-15,18-23H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325461 (1-(3-methoxybenzyl)-3-(1-(1-(pyridin-4-ylmethyl)pi...) Show SMILES COc1cccc(Cn2c3ccccc3n(C3CCN(CC3)C(=O)C3CCN(Cc4ccncc4)CC3)c2=O)c1 Show InChI InChI=1S/C32H37N5O3/c1-40-28-6-4-5-25(21-28)23-36-29-7-2-3-8-30(29)37(32(36)39)27-13-19-35(20-14-27)31(38)26-11-17-34(18-12-26)22-24-9-15-33-16-10-24/h2-10,15-16,21,26-27H,11-14,17-20,22-23H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325473 (1-isobutyl-3-(1-(1-(pyridin-4-ylmethyl)piperidine-...) Show SMILES CC(C)Cn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C28H37N5O2/c1-21(2)19-32-25-5-3-4-6-26(25)33(28(32)35)24-11-17-31(18-12-24)27(34)23-9-15-30(16-10-23)20-22-7-13-29-14-8-22/h3-8,13-14,21,23-24H,9-12,15-20H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325448 (1-(2-morpholinoethyl)-3-(1-(1-(pyridin-4-ylmethyl)...) Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2n(CCN2CCOCC2)c1=O Show InChI InChI=1S/C30H40N6O3/c37-29(25-7-13-33(14-8-25)23-24-5-11-31-12-6-24)34-15-9-26(10-16-34)36-28-4-2-1-3-27(28)35(30(36)38)18-17-32-19-21-39-22-20-32/h1-6,11-12,25-26H,7-10,13-23H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441652 (CHEMBL2437433) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(-c3cnccn3)c2=O)ccn1 Show InChI InChI=1S/C28H31FN8O2/c29-21-1-2-23-24(16-21)37(26-17-31-9-10-33-26)28(39)36(23)22-6-13-35(14-7-22)27(38)20-4-11-34(12-5-20)18-19-3-8-32-25(30)15-19/h1-3,8-10,15-17,20,22H,4-7,11-14,18H2,(H2,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441649 (CHEMBL2437416) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3[nH]c2=O)ccn1 Show InChI InChI=1S/C24H30N6O2/c25-22-15-17(5-10-26-22)16-28-11-6-18(7-12-28)23(31)29-13-8-19(9-14-29)30-21-4-2-1-3-20(21)27-24(30)32/h1-5,10,15,18-19H,6-9,11-14,16H2,(H2,25,26)(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325469 (1-(2-isopropoxyethyl)-3-(1-(1-(pyridin-4-ylmethyl)...) Show SMILES CC(C)OCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C29H39N5O3/c1-22(2)37-20-19-33-26-5-3-4-6-27(26)34(29(33)36)25-11-17-32(18-12-25)28(35)24-9-15-31(16-10-24)21-23-7-13-30-14-8-23/h3-8,13-14,22,24-25H,9-12,15-21H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441646 (CHEMBL2437421) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3n(CCN3CCOCC3)c2=O)ccn1 Show InChI InChI=1S/C30H41N7O3/c31-28-21-23(5-10-32-28)22-34-11-6-24(7-12-34)29(38)35-13-8-25(9-14-35)37-27-4-2-1-3-26(27)36(30(37)39)16-15-33-17-19-40-20-18-33/h1-5,10,21,24-25H,6-9,11-20,22H2,(H2,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325467 (1-(3-ethoxypropyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES CCOCCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C29H39N5O3/c1-2-37-21-5-16-33-26-6-3-4-7-27(26)34(29(33)36)25-12-19-32(20-13-25)28(35)24-10-17-31(18-11-24)22-23-8-14-30-15-9-23/h3-4,6-9,14-15,24-25H,2,5,10-13,16-22H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325462 (1-(4-chlorobenzyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES Clc1ccc(Cn2c3ccccc3n(C3CCN(CC3)C(=O)C3CCN(Cc4ccncc4)CC3)c2=O)cc1 Show InChI InChI=1S/C31H34ClN5O2/c32-26-7-5-23(6-8-26)22-36-28-3-1-2-4-29(28)37(31(36)39)27-13-19-35(20-14-27)30(38)25-11-17-34(18-12-25)21-24-9-15-33-16-10-24/h1-10,15-16,25,27H,11-14,17-22H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441637 (CHEMBL2437430) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(-c3cc(F)cc(F)c3)c2=O)ccn1 Show InChI InChI=1S/C30H31F3N6O2/c31-21-1-2-26-27(17-21)39(25-15-22(32)14-23(33)16-25)30(41)38(26)24-6-11-37(12-7-24)29(40)20-4-9-36(10-5-20)18-19-3-8-35-28(34)13-19/h1-3,8,13-17,20,24H,4-7,9-12,18H2,(H2,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325472 (1-(2-hydroxyethyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES OCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C26H33N5O3/c32-18-17-30-23-3-1-2-4-24(23)31(26(30)34)22-9-15-29(16-10-22)25(33)21-7-13-28(14-8-21)19-20-5-11-27-12-6-20/h1-6,11-12,21-22,32H,7-10,13-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177543 (1-(3-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1cccc(CN2CCCCC2)c1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C24H36N4O/c1-2-10-28(11-3-1)19-22-6-4-7-24(17-22)29-15-5-12-27-13-8-21(9-14-27)16-23-18-25-20-26-23/h4,6-7,17-18,20-21H,1-3,5,8-16,19H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441642 (CHEMBL2437425) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(CC(F)(F)F)c2=O)ccn1 Show InChI InChI=1S/C26H30F4N6O2/c27-19-1-2-21-22(14-19)35(16-26(28,29)30)25(38)36(21)20-6-11-34(12-7-20)24(37)18-4-9-33(10-5-18)15-17-3-8-32-23(31)13-17/h1-3,8,13-14,18,20H,4-7,9-12,15-16H2,(H2,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441647 (CHEMBL2437420) Show SMILES COCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccnc(N)c3)CC2)c1=O Show InChI InChI=1S/C27H36N6O3/c1-36-17-16-32-23-4-2-3-5-24(23)33(27(32)35)22-9-14-31(15-10-22)26(34)21-7-12-30(13-8-21)19-20-6-11-29-25(28)18-20/h2-6,11,18,21-22H,7-10,12-17,19H2,1H3,(H2,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325470 (1-(2-ethoxyethyl)-3-(1-(1-(pyridin-4-ylmethyl)pipe...) Show SMILES CCOCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C28H37N5O3/c1-2-36-20-19-32-25-5-3-4-6-26(25)33(28(32)35)24-11-17-31(18-12-24)27(34)23-9-15-30(16-10-23)21-22-7-13-29-14-8-22/h3-8,13-14,23-24H,2,9-12,15-21H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325468 (1-(2-phenoxyethyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2n(CCOc2ccccc2)c1=O Show InChI InChI=1S/C32H37N5O3/c38-31(26-12-18-34(19-13-26)24-25-10-16-33-17-11-25)35-20-14-27(15-21-35)37-30-9-5-4-8-29(30)36(32(37)39)22-23-40-28-6-2-1-3-7-28/h1-11,16-17,26-27H,12-15,18-24H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325451 (1-(1-(1-(pyridin-4-ylmethyl)piperidine-4-carbonyl)...) Show SMILES O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C24H29N5O2/c30-23(19-7-13-27(14-8-19)17-18-5-11-25-12-6-18)28-15-9-20(10-16-28)29-22-4-2-1-3-21(22)26-24(29)31/h1-6,11-12,19-20H,7-10,13-17H2,(H,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325471 (1-(2-methoxyethyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES COCCn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C27H35N5O3/c1-35-19-18-31-24-4-2-3-5-25(24)32(27(31)34)23-10-16-30(17-11-23)26(33)22-8-14-29(15-9-22)20-21-6-12-28-13-7-21/h2-7,12-13,22-23H,8-11,14-20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325463 (1-(3-chlorobenzyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES Clc1cccc(Cn2c3ccccc3n(C3CCN(CC3)C(=O)C3CCN(Cc4ccncc4)CC3)c2=O)c1 Show InChI InChI=1S/C31H34ClN5O2/c32-26-5-3-4-24(20-26)22-36-28-6-1-2-7-29(28)37(31(36)39)27-12-18-35(19-13-27)30(38)25-10-16-34(17-11-25)21-23-8-14-33-15-9-23/h1-9,14-15,20,25,27H,10-13,16-19,21-22H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383459 (CHEMBL2031619) Show SMILES O=c1ccnc2c(cccn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C20H24N6OS/c27-17-6-9-21-18-16(5-4-12-26(17)18)19-22-23-20(28-19)25-13-7-15(8-14-25)24-10-2-1-3-11-24/h4-6,9,12,15H,1-3,7-8,10-11,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441641 (CHEMBL2437426) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(CC3CC3)c2=O)ccn1 Show InChI InChI=1S/C28H35FN6O2/c29-22-3-4-24-25(16-22)34(18-19-1-2-19)28(37)35(24)23-8-13-33(14-9-23)27(36)21-6-11-32(12-7-21)17-20-5-10-31-26(30)15-20/h3-5,10,15-16,19,21,23H,1-2,6-9,11-14,17-18H2,(H2,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441645 (CHEMBL2437422) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(CCN3CCOCC3)c2=O)ccn1 Show InChI InChI=1S/C30H40FN7O3/c31-24-1-2-26-27(20-24)37(14-13-34-15-17-41-18-16-34)30(40)38(26)25-6-11-36(12-7-25)29(39)23-4-9-35(10-5-23)21-22-3-8-33-28(32)19-22/h1-3,8,19-20,23,25H,4-7,9-18,21H2,(H2,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50383442 (CHEMBL2031602) Show SMILES Cc1nnc2ccc(cn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C19H25N7S/c1-14-20-21-17-6-5-15(13-26(14)17)18-22-23-19(27-18)25-11-7-16(8-12-25)24-9-3-2-4-10-24/h5-6,13,16H,2-4,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441654 (CHEMBL2437431) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(-c3ccccn3)c2=O)ccn1 Show InChI InChI=1S/C29H32FN7O2/c30-22-4-5-24-25(18-22)37(27-3-1-2-11-33-27)29(39)36(24)23-9-15-35(16-10-23)28(38)21-7-13-34(14-8-21)19-20-6-12-32-26(31)17-20/h1-6,11-12,17-18,21,23H,7-10,13-16,19H2,(H2,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Mus musculus)	BDBM50383459 (CHEMBL2031619) Show SMILES O=c1ccnc2c(cccn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C20H24N6OS/c27-17-6-9-21-18-16(5-4-12-26(17)18)19-22-23-20(28-19)25-13-7-15(8-14-25)24-10-2-1-3-11-24/h4-6,9,12,15H,1-3,7-8,10-11,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from mouse histamine H3 receptor				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441638 (CHEMBL2437429) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(-c3ccc(F)c(F)c3)c2=O)ccn1 Show InChI InChI=1S/C30H31F3N6O2/c31-21-1-4-26-27(16-21)39(23-2-3-24(32)25(33)17-23)30(41)38(26)22-8-13-37(14-9-22)29(40)20-6-11-36(12-7-20)18-19-5-10-35-28(34)15-19/h1-5,10,15-17,20,22H,6-9,11-14,18H2,(H2,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177536 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C24H36N4O/c1-2-11-28(12-3-1)19-22-5-7-24(8-6-22)29-16-4-13-27-14-9-21(10-15-27)17-23-18-25-20-26-23/h5-8,18,20-21H,1-4,9-17,19H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177531 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(CCN2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C25H38N4O/c1-2-12-28(13-3-1)15-9-22-5-7-25(8-6-22)30-18-4-14-29-16-10-23(11-17-29)19-24-20-26-21-27-24/h5-8,20-21,23H,1-4,9-19H2,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177538 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(COc1ccc(CN2CCC(CC2)N2CCCCC2)cc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C29H45N5O/c1-2-14-34(15-3-1)28-11-18-33(19-12-28)23-26-5-7-29(8-6-26)35-20-4-13-32-16-9-25(10-17-32)21-27-22-30-24-31-27/h5-8,22,24-25,28H,1-4,9-21,23H2,(H,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177530 (4-((1H-imidazol-4-yl)methyl)-1-(3-(3-(cyclohexylox...) Show SMILES C(COc1cccc(OC2CCCCC2)c1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C24H35N3O2/c1-2-6-22(7-3-1)29-24-9-4-8-23(17-24)28-15-5-12-27-13-10-20(11-14-27)16-21-18-25-19-26-21/h4,8-9,17-20,22H,1-3,5-7,10-16H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383444 (CHEMBL2031604) Show SMILES C1CCN(CC1)C1CCN(CC1)c1nnc(s1)-c1cccc2ccnn12 Show InChI InChI=1S/C19H24N6S/c1-2-11-23(12-3-1)15-8-13-24(14-9-15)19-22-21-18(26-19)17-6-4-5-16-7-10-20-25(16)17/h4-7,10,15H,1-3,8-9,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383442 (CHEMBL2031602) Show SMILES Cc1nnc2ccc(cn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C19H25N7S/c1-14-20-21-17-6-5-15(13-26(14)17)18-22-23-19(27-18)25-11-7-16(8-12-25)24-9-3-2-4-10-24/h5-6,13,16H,2-4,7-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441644 (CHEMBL2437423) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(CCCC(F)(F)F)c2=O)ccn1 Show InChI InChI=1S/C28H34F4N6O2/c29-21-2-3-23-24(17-21)37(11-1-9-28(30,31)32)27(40)38(23)22-7-14-36(15-8-22)26(39)20-5-12-35(13-6-20)18-19-4-10-34-25(33)16-19/h2-4,10,16-17,20,22H,1,5-9,11-15,18H2,(H2,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177551 (4-((1H-imidazol-4-yl)methyl)-N-(thiazol-2-yl)piper...) Show SMILES O=C(Nc1nccs1)N1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C13H17N5OS/c19-13(17-12-15-3-6-20-12)18-4-1-10(2-5-18)7-11-8-14-9-16-11/h3,6,8-10H,1-2,4-5,7H2,(H,14,16)(H,15,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177542 (1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES FC1(F)CCN(Cc2ccc(OCCCN3CCC(Cc4cnc[nH]4)CC3)cc2)CC1 Show InChI InChI=1S/C24H34F2N4O/c25-24(26)8-13-30(14-9-24)18-21-2-4-23(5-3-21)31-15-1-10-29-11-6-20(7-12-29)16-22-17-27-19-28-22/h2-5,17,19-20H,1,6-16,18H2,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177535 (CHEMBL379445 | N-(4-(3-(4-((1H-imidazol-4-yl)methy...) Show SMILES CCN(CC)Cc1ccc(OCCCN2CCC(Cc3cnc[nH]3)CC2)cc1 Show InChI InChI=1S/C23H36N4O/c1-3-26(4-2)18-21-6-8-23(9-7-21)28-15-5-12-27-13-10-20(11-14-27)16-22-17-24-19-25-22/h6-9,17,19-20H,3-5,10-16,18H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441653 (CHEMBL2437432) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(-c3ncccn3)c2=O)ccn1 Show InChI InChI=1S/C28H31FN8O2/c29-21-2-3-23-24(17-21)37(27-32-9-1-10-33-27)28(39)36(23)22-7-14-35(15-8-22)26(38)20-5-12-34(13-6-20)18-19-4-11-31-25(30)16-19/h1-4,9-11,16-17,20,22H,5-8,12-15,18H2,(H2,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50175839 (4-((1H-imidazol-4-yl)methyl)-1-(3-phenoxypropyl)pi...) Show SMILES C(COc1ccccc1)CN1CCC(Cc2cnc[nH]2)CC1 Show InChI InChI=1S/C18H25N3O/c1-2-5-18(6-3-1)22-12-4-9-21-10-7-16(8-11-21)13-17-14-19-15-20-17/h1-3,5-6,14-16H,4,7-13H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325474 (1-methyl-3-(1-(1-(pyridin-4-ylmethyl)piperidine-4-...) Show SMILES Cn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C25H31N5O2/c1-27-22-4-2-3-5-23(22)30(25(27)32)21-10-16-29(17-11-21)24(31)20-8-14-28(15-9-20)18-19-6-12-26-13-7-19/h2-7,12-13,20-21H,8-11,14-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383448 (CHEMBL2031608) Show SMILES O=C(N1CCC1)c1cccc(n1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C21H28N6OS/c28-20(26-12-5-13-26)18-7-4-6-17(22-18)19-23-24-21(29-19)27-14-8-16(9-15-27)25-10-2-1-3-11-25/h4,6-7,16H,1-3,5,8-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50325464 (1-(2-chlorobenzyl)-3-(1-(1-(pyridin-4-ylmethyl)pip...) Show SMILES Clc1ccccc1Cn1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccncc3)CC2)c1=O Show InChI InChI=1S/C31H34ClN5O2/c32-27-6-2-1-5-25(27)22-36-28-7-3-4-8-29(28)37(31(36)39)26-13-19-35(20-14-26)30(38)24-11-17-34(18-12-24)21-23-9-15-33-16-10-23/h1-10,15-16,24,26H,11-14,17-22H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylhistamine from histamine H3 receptor in guinea pig brain				Bioorg Med Chem Lett 20: 5004-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.052 BindingDB Entry DOI: 10.7270/Q2N016QS
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50383445 (CHEMBL2031605) Show SMILES C1CCN(CC1)C1CCN(CC1)c1nnc(s1)-c1cccc2cccnc12 Show InChI InChI=1S/C21H25N5S/c1-2-12-25(13-3-1)17-9-14-26(15-10-17)21-24-23-20(27-21)18-8-4-6-16-7-5-11-22-19(16)18/h4-8,11,17H,1-3,9-10,12-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...				Bioorg Med Chem Lett 22: 3354-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.076 BindingDB Entry DOI: 10.7270/Q2DN462S
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441651 (CHEMBL2437417) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3n(CCCC(F)(F)F)c2=O)ccn1 Show InChI InChI=1S/C28H35F3N6O2/c29-28(30,31)11-3-13-36-23-4-1-2-5-24(23)37(27(36)39)22-9-16-35(17-10-22)26(38)21-7-14-34(15-8-21)19-20-6-12-33-25(32)18-20/h1-2,4-6,12,18,21-22H,3,7-11,13-17,19H2,(H2,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50177544 (1-(4-(2-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...) Show SMILES C(CN1CCC(Cc2cnc[nH]2)CC1)Oc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C23H34N4O/c1-2-10-27(11-3-1)18-21-4-6-23(7-5-21)28-15-14-26-12-8-20(9-13-26)16-22-17-24-19-25-22/h4-7,17,19-20H,1-3,8-16,18H2,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptor				Bioorg Med Chem Lett 16: 989-94 (2006) Article DOI: 10.1016/j.bmcl.2005.10.087 BindingDB Entry DOI: 10.7270/Q2SJ1K5X
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM50441640 (CHEMBL2437427) Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccc(F)cc3n(C3CCCC3)c2=O)ccn1 Show InChI InChI=1S/C29H37FN6O2/c30-22-5-6-25-26(18-22)36(23-3-1-2-4-23)29(38)35(25)24-10-15-34(16-11-24)28(37)21-8-13-33(14-9-21)19-20-7-12-32-27(31)17-20/h5-7,12,17-18,21,23-24H,1-4,8-11,13-16,19H2,(H2,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates				Bioorg Med Chem Lett 23: 6001-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.012 BindingDB Entry DOI: 10.7270/Q2542Q1F
					More data for this Ligand-Target Pair

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