Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315368 (CHEMBL1090182 | benzyl 1-acetyl-2-(4-methoxy-3-(tr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315367 (CHEMBL1089847 | benzyl 1-acetyl-2-(4-fluoro-3-(tri...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315366 (CHEMBL1092661 | benzyl 1-acetyl-2-(3-(trifluoromet...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315362 (CHEMBL1092325 | benzyl 1-acetyl-2-(4-cyanobenzyl)p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384300 (CHEMBL2030661) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315359 (CHEMBL1092255 | benzyl 1-acetyl-2-(4-fluorobenzyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384302 (CHEMBL2030663) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315365 (CHEMBL1092338 | benzyl 1-acetyl-2-(3-(methylsulfon...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384298 (CHEMBL2030659) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384301 (CHEMBL2030662) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315350 ((+)-benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315360 (CHEMBL1092256 | benzyl 1-acetyl-2-(4-chlorobenzyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315376 (CHEMBL1093303 | benzyl 2-benzyl-1-(cyclopropanecar...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315363 (CHEMBL1092336 | benzyl 1-acetyl-2-(3-cyanobenzyl)p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315361 ((+)-benzyl 1-acetyl-2-(4-(methylsulfonyl)benzyl)py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315357 (CHEMBL1091212 | benzyl 1-acetyl-2-(4-methoxybenzyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315373 (2-benzyl 1-methyl 2-benzylpyrrolidine-1,2-dicarbox...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384307 (CHEMBL2030669) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315358 (CHEMBL1091213 | benzyl 1-acetyl-2-(4-(trifluoromet...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315350 ((+)-benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315356 (CHEMBL1091211 | benzyl 1-acetyl-2-(4-methylbenzyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315355 (CHEMBL1090196 | benzyl 1-acetyl-2-(thiophen-3-ylme...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315350 ((+)-benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315389 (4-methylbenzyl 1-acetyl-2-benzylpyrrolidine-2-carb...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315350 ((+)-benzyl 1-acetyl-2-benzylpyrrolidine-2-carboxyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315361 ((+)-benzyl 1-acetyl-2-(4-(methylsulfonyl)benzyl)py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315361 ((+)-benzyl 1-acetyl-2-(4-(methylsulfonyl)benzyl)py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315353 (CHEMBL1088881 | benzyl 1-acetyl-2-(cyclohexylmethy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384305 (CHEMBL2030667) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315375 (CHEMBL1088923 | benzyl 2-benzyl-1-propionylpyrroli...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315388 (4-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carb...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384304 (CHEMBL2030665) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315372 (CHEMBL1088917 | benzyl 2-benzyl-1-(methylsulfonyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315374 (CHEMBL1088922 | benzyl 2-benzyl-1-(ethylcarbamoyl)...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315354 (CHEMBL1090195 | benzyl 1-acetyl-2-(pyridin-4-ylmet...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315387 (3-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carb...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315382 (1-phenylethyl 1-acetyl-2-benzylpyrrolidine-2-carbo...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315377 (CHEMBL1092317 | benzyl 1-benzoyl-2-benzylpyrrolidi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315369 (CHEMBL1090183 | benzyl 1-acetyl-2-(4-fluoro-2-(tri...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384306 (CHEMBL2030668) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315364 (CHEMBL1092337 | benzyl 1-acetyl-2-(2-cyanobenzyl)p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315390 (4-(trifluoromethyl)benzyl 1-acetyl-2-benzylpyrroli...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315386 (2-chlorobenzyl 1-acetyl-2-benzylpyrrolidine-2-carb...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315351 (CHEMBL1088879 | benzyl 1-acetyl-2-phenethylpyrroli...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315383 (CHEMBL1089178 | phenethyl 1-acetyl-2-benzylpyrroli...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384308 (CHEMBL2030666) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384303 (CHEMBL2030664) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315379 (1-acetyl-N,2-dibenzyl-N-methylpyrrolidine-2-carbox...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50384299 (CHEMBL2030660) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma Curated by ChEMBL | Assay Description Inhibition of rat KCC2 expressed in human Sk-Hep cells assessed as induction off Rb+ flux by atomic absorption spectroscopic analysis | Bioorg Med Chem Lett 22: 3978-82 (2012) Article DOI: 10.1016/j.bmcl.2012.04.097 BindingDB Entry DOI: 10.7270/Q27P90FX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 12 member 5 (Rattus norvegicus) | BDBM50315384 (CHEMBL1089191 | cyclohexylmethyl 1-acetyl-2-benzyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Pharma SA Curated by ChEMBL | Assay Description Antagonist activity of rat KCC2 transporter expressed in human SK-Hep cells assessed as inhibition of N-ethylmaleimide-mediated Rb+ influx after 10 m... | Bioorg Med Chem Lett 20: 2542-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.092 BindingDB Entry DOI: 10.7270/Q2BZ665C | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 101 total ) | Next | Last >> |