Compile Data Set for Download or QSAR

Found 411 hits with Last Name = 'smith torhan' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210235 (4-(2-(aminomethyl)phenyl)-1-(1-phenylpentyl)piperi...) Show SMILES CCCCC(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:4.3| Show InChI InChI=1S/C23H32N2O/c1-2-3-13-22(19-9-5-4-6-10-19)25-16-14-23(26,15-17-25)21-12-8-7-11-20(21)18-24/h4-12,22,26H,2-3,13-18,24H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210242 (4-(2-(aminomethyl)phenyl)-1-(bis(2-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1F)c1ccccc1F Show InChI InChI=1S/C25H26F2N2O/c26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28/h1-12,24,30H,13-17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210229 (4-(2-(aminomethyl)phenyl)-1-((2-chlorophenyl)(phen...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1Cl |w:15.16| Show InChI InChI=1S/C25H27ClN2O/c26-23-13-7-5-11-21(23)24(19-8-2-1-3-9-19)28-16-14-25(29,15-17-28)22-12-6-4-10-20(22)18-27/h1-13,24,29H,14-18,27H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210247 (4-(2-(aminomethyl)phenyl)-1-(1-phenylhexyl)piperid...) Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:5.4| Show InChI InChI=1S/C24H34N2O/c1-2-3-5-14-23(20-10-6-4-7-11-20)26-17-15-24(27,16-18-26)22-13-9-8-12-21(22)19-25/h4,6-13,23,27H,2-3,5,14-19,25H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210206 (4-(2-(aminomethyl)phenyl)-1-(dio-tolylmethyl)piper...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1C Show InChI InChI=1S/C27H32N2O/c1-20-9-3-6-12-23(20)26(24-13-7-4-10-21(24)2)29-17-15-27(30,16-18-29)25-14-8-5-11-22(25)19-28/h3-14,26,30H,15-19,28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210212 (4-(2-(aminomethyl)phenyl)-1-(bis(2-chlorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C25H26Cl2N2O/c26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28/h1-12,24,30H,13-17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210238 (1-(bis(2-chlorophenyl)methyl)-4-(2-((4-(isopropyls...) Show SMILES CC(C)S(=O)(=O)N1CCN(Cc2ccccc2C2(O)CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)CC1 Show InChI InChI=1S/C32H39Cl2N3O3S/c1-24(2)41(39,40)37-21-19-35(20-22-37)23-25-9-3-6-12-28(25)32(38)15-17-36(18-16-32)31(26-10-4-7-13-29(26)33)27-11-5-8-14-30(27)34/h3-14,24,31,38H,15-23H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210383 (4-phenyl-1-(phenyl(o-tolyl)methyl)piperidin-4-ol |...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C25H27NO/c1-20-10-8-9-15-23(20)24(21-11-4-2-5-12-21)26-18-16-25(27,17-19-26)22-13-6-3-7-14-22/h2-15,24,27H,16-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][14Tyr]nociceptin FQ from human cloned NOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210246 (1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)m...) Show SMILES CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C26H28Cl2N2O/c1-29-18-19-8-2-5-11-22(19)26(31)14-16-30(17-15-26)25(20-9-3-6-12-23(20)27)21-10-4-7-13-24(21)28/h2-13,25,29,31H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210209 (4-(2-(aminomethyl)phenyl)-1-(phenyl(o-tolyl)methyl...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:7.8| Show InChI InChI=1S/C26H30N2O/c1-20-9-5-7-13-23(20)25(21-10-3-2-4-11-21)28-17-15-26(29,16-18-28)24-14-8-6-12-22(24)19-27/h2-14,25,29H,15-19,27H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210214 (1-(bis(2-chlorophenyl)methyl)-4-(2-((4-(ethylsulfo...) Show SMILES CCS(=O)(=O)N1CCN(Cc2ccccc2C2(O)CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)CC1 Show InChI InChI=1S/C31H37Cl2N3O3S/c1-2-40(38,39)36-21-19-34(20-22-36)23-24-9-3-6-12-27(24)31(37)15-17-35(18-16-31)30(25-10-4-7-13-28(25)32)26-11-5-8-14-29(26)33/h3-14,30,37H,2,15-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210393 (1-((2-methoxyphenyl)(phenyl)methyl)-4-phenylpiperi...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C25H27NO2/c1-28-23-15-9-8-14-22(23)24(20-10-4-2-5-11-20)26-18-16-25(27,17-19-26)21-12-6-3-7-13-21/h2-15,24,27H,16-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210211 (4-(2-(aminomethyl)phenyl)-1-((2-bromophenyl)(pheny...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1Br |w:15.16| Show InChI InChI=1S/C25H27BrN2O/c26-23-13-7-5-11-21(23)24(19-8-2-1-3-9-19)28-16-14-25(29,15-17-28)22-12-6-4-10-20(22)18-27/h1-13,24,29H,14-18,27H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210208 (4-(2-(aminomethyl)phenyl)-1-benzhydrylpiperidin-4-...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H28N2O/c26-19-22-13-7-8-14-23(22)25(28)15-17-27(18-16-25)24(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-14,24,28H,15-19,26H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210208 (4-(2-(aminomethyl)phenyl)-1-benzhydrylpiperidin-4-...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H28N2O/c26-19-22-13-7-8-14-23(22)25(28)15-17-27(18-16-25)24(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-14,24,28H,15-19,26H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210245 (4-(2-(aminomethyl)phenyl)-1-(bis(2-bromophenyl)met...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Br)c1ccccc1Br Show InChI InChI=1S/C25H26Br2N2O/c26-22-11-5-2-8-19(22)24(20-9-3-6-12-23(20)27)29-15-13-25(30,14-16-29)21-10-4-1-7-18(21)17-28/h1-12,24,30H,13-17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210221 (1-(bis(2-chlorophenyl)methyl)-4-(2-(piperazin-1-yl...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1CN1CCNCC1 Show InChI InChI=1S/C29H33Cl2N3O/c30-26-11-5-2-8-23(26)28(24-9-3-6-12-27(24)31)34-17-13-29(35,14-18-34)25-10-4-1-7-22(25)21-33-19-15-32-16-20-33/h1-12,28,32,35H,13-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210234 (1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...) Show SMILES CNC(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C27H29Cl2N3O2/c1-30-26(33)31-18-19-8-2-5-11-22(19)27(34)14-16-32(17-15-27)25(20-9-3-6-12-23(20)28)21-10-4-7-13-24(21)29/h2-13,25,34H,14-18H2,1H3,(H2,30,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210383 (4-phenyl-1-(phenyl(o-tolyl)methyl)piperidin-4-ol |...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C25H27NO/c1-20-10-8-9-15-23(20)24(21-11-4-2-5-12-21)26-18-16-25(27,17-19-26)22-13-6-3-7-14-22/h2-15,24,27H,16-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][14Tyr]nociceptin FQ from human cloned NOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210235 (4-(2-(aminomethyl)phenyl)-1-(1-phenylpentyl)piperi...) Show SMILES CCCCC(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:4.3| Show InChI InChI=1S/C23H32N2O/c1-2-3-13-22(19-9-5-4-6-10-19)25-16-14-23(26,15-17-25)21-12-8-7-11-20(21)18-24/h4-12,22,26H,2-3,13-18,24H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210247 (4-(2-(aminomethyl)phenyl)-1-(1-phenylhexyl)piperid...) Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:5.4| Show InChI InChI=1S/C24H34N2O/c1-2-3-5-14-23(20-10-6-4-7-11-20)26-17-15-24(27,16-18-26)22-13-9-8-12-21(22)19-25/h4,6-13,23,27H,2-3,5,14-19,25H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210240 (1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiper...) Show SMILES CN1CCN(Cc2ccccc2C2(O)CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)CC1 Show InChI InChI=1S/C30H35Cl2N3O/c1-33-18-20-34(21-19-33)22-23-8-2-5-11-26(23)30(36)14-16-35(17-15-30)29(24-9-3-6-12-27(24)31)25-10-4-7-13-28(25)32/h2-13,29,36H,14-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210392 (4-phenyl-1-(phenyl(m-tolyl)methyl)piperidin-4-ol |...) Show SMILES Cc1cccc(c1)C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C25H27NO/c1-20-9-8-12-22(19-20)24(21-10-4-2-5-11-21)26-17-15-25(27,16-18-26)23-13-6-3-7-14-23/h2-14,19,24,27H,15-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210389 (1-(bis(2-methoxyphenyl)methyl)-4-phenylpiperidin-4...) Show SMILES COc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1OC Show InChI InChI=1S/C26H29NO3/c1-29-23-14-8-6-12-21(23)25(22-13-7-9-15-24(22)30-2)27-18-16-26(28,17-19-27)20-10-4-3-5-11-20/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210404 (1-((2-chlorophenyl)(phenyl)methyl)-4-phenylpiperid...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1Cl)c1ccccc1 |w:7.7| Show InChI InChI=1S/C24H24ClNO/c25-22-14-8-7-13-21(22)23(19-9-3-1-4-10-19)26-17-15-24(27,16-18-26)20-11-5-2-6-12-20/h1-14,23,27H,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210387 (1-(dio-tolylmethyl)-4-phenylpiperidin-4-ol | CHEMB...) Show SMILES Cc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1C Show InChI InChI=1S/C26H29NO/c1-20-10-6-8-14-23(20)25(24-15-9-7-11-21(24)2)27-18-16-26(28,17-19-27)22-12-4-3-5-13-22/h3-15,25,28H,16-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210236 (CHEMBL437177 | N-(2-(1-(bis(2-chlorophenyl)methyl)...) Show SMILES CC(C)S(=O)(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C28H32Cl2N2O3S/c1-20(2)36(34,35)31-19-21-9-3-6-12-24(21)28(33)15-17-32(18-16-28)27(22-10-4-7-13-25(22)29)23-11-5-8-14-26(23)30/h3-14,20,27,31,33H,15-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210197 (4-(2-(aminomethyl)phenyl)-1-(cycloheptylmethyl)pip...) Show SMILES NCc1ccccc1C1(O)CCN(CC2CCCCCC2)CC1 Show InChI InChI=1S/C20H32N2O/c21-15-18-9-5-6-10-19(18)20(23)11-13-22(14-12-20)16-17-7-3-1-2-4-8-17/h5-6,9-10,17,23H,1-4,7-8,11-16,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210377 (4-phenyl-1-(1-phenylpentyl)piperidin-4-ol | CHEMBL...) Show SMILES CCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:4.3| Show InChI InChI=1S/C22H29NO/c1-2-3-14-21(19-10-6-4-7-11-19)23-17-15-22(24,16-18-23)20-12-8-5-9-13-20/h4-13,21,24H,2-3,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210398 (1-((2-fluorophenyl)(phenyl)methyl)-4-phenylpiperid...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1F)c1ccccc1 |w:7.7| Show InChI InChI=1S/C24H24FNO/c25-22-14-8-7-13-21(22)23(19-9-3-1-4-10-19)26-17-15-24(27,16-18-26)20-11-5-2-6-12-20/h1-14,23,27H,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210217 (4-(2-(aminomethyl)phenyl)-1-(4,4-dimethyl-1,2,3,4-...) Show SMILES CC1(C)CCC(N2CCC(O)(CC2)c2ccccc2CN)c2ccccc12 |w:5.5| Show InChI InChI=1S/C24H32N2O/c1-23(2)12-11-22(19-8-4-6-10-21(19)23)26-15-13-24(27,14-16-26)20-9-5-3-7-18(20)17-25/h3-10,22,27H,11-17,25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210203 (1-(bis(2-chlorophenyl)methyl)-4-(2-(morpholinometh...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1CN1CCOCC1 Show InChI InChI=1S/C29H32Cl2N2O2/c30-26-11-5-2-8-23(26)28(24-9-3-6-12-27(24)31)33-15-13-29(34,14-16-33)25-10-4-1-7-22(25)21-32-17-19-35-20-18-32/h1-12,28,34H,13-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210415 (1-(bis(2-fluorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1F)c1ccccc1F)c1ccccc1 Show InChI InChI=1S/C24H23F2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210394 (1-((2-(hydroxymethyl)phenyl)(phenyl)methyl)-4-phen...) Show SMILES OCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C25H27NO2/c27-19-21-11-7-8-14-23(21)24(20-9-3-1-4-10-20)26-17-15-25(28,16-18-26)22-12-5-2-6-13-22/h1-14,24,27-28H,15-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210407 (1-(4-methyl-1-phenylpentyl)-4-phenylpiperidin-4-ol...) Show SMILES CC(C)CCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:5.4| Show InChI InChI=1S/C23H31NO/c1-19(2)13-14-22(20-9-5-3-6-10-20)24-17-15-23(25,16-18-24)21-11-7-4-8-12-21/h3-12,19,22,25H,13-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210216 (4-(2-(aminomethyl)phenyl)-1-(bis(3-fluorophenyl)me...) Show SMILES NCc1ccccc1C1(O)CCN(CC1)C(c1cccc(F)c1)c1cccc(F)c1 Show InChI InChI=1S/C25H26F2N2O/c26-21-8-3-6-18(15-21)24(19-7-4-9-22(27)16-19)29-13-11-25(30,12-14-29)23-10-2-1-5-20(23)17-28/h1-10,15-16,24,30H,11-14,17,28H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210224 (1-benzhydryl-4-o-tolylpiperidin-4-ol | CHEMBL23227...) Show SMILES Cc1ccccc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27NO/c1-20-10-8-9-15-23(20)25(27)16-18-26(19-17-25)24(21-11-4-2-5-12-21)22-13-6-3-7-14-22/h2-15,24,27H,16-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210391 (1-((2-bromophenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1Br)c1ccccc1 |w:7.7| Show InChI InChI=1S/C24H24BrNO/c25-22-14-8-7-13-21(22)23(19-9-3-1-4-10-19)26-17-15-24(27,16-18-26)20-11-5-2-6-12-20/h1-14,23,27H,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210395 (4-phenyl-1-(phenyl(2-(trifluoromethyl)phenyl)methy...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1C(F)(F)F)c1ccccc1 |w:7.8| Show InChI InChI=1S/C25H24F3NO/c26-25(27,28)22-14-8-7-13-21(22)23(19-9-3-1-4-10-19)29-17-15-24(30,16-18-29)20-11-5-2-6-12-20/h1-14,23,30H,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210225 (1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...) Show SMILES CCNC(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C28H31Cl2N3O2/c1-2-31-27(34)32-19-20-9-3-6-12-23(20)28(35)15-17-33(18-16-28)26(21-10-4-7-13-24(21)29)22-11-5-8-14-25(22)30/h3-14,26,35H,2,15-19H2,1H3,(H2,31,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210223 (1-benzhydryl-4-phenylpiperidin-4-ol | CHEMBL228690) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25NO/c26-24(22-14-8-3-9-15-22)16-18-25(19-17-24)23(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-15,23,26H,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210223 (1-benzhydryl-4-phenylpiperidin-4-ol | CHEMBL228690) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H25NO/c26-24(22-14-8-3-9-15-22)16-18-25(19-17-24)23(20-10-4-1-5-11-20)21-12-6-2-7-13-21/h1-15,23,26H,16-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210418 (4-phenyl-1-(1-phenylhexyl)piperidin-4-ol | CHEMBL2...) Show SMILES CCCCCC(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:5.4| Show InChI InChI=1S/C23H31NO/c1-2-3-6-15-22(20-11-7-4-8-12-20)24-18-16-23(25,17-19-24)21-13-9-5-10-14-21/h4-5,7-14,22,25H,2-3,6,15-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210249 (1-benzhydryl-4-(4-fluorophenyl)piperidin-4-ol | CH...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C24H24FNO/c25-22-13-11-21(12-14-22)24(27)15-17-26(18-16-24)23(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-14,23,27H,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210231 (CHEMBL232478 | N-(2-(1-(bis(2-chlorophenyl)methyl)...) Show SMILES CCCS(=O)(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C28H32Cl2N2O3S/c1-2-19-36(34,35)31-20-21-9-3-6-12-24(21)28(33)15-17-32(18-16-28)27(22-10-4-7-13-25(22)29)23-11-5-8-14-26(23)30/h3-14,27,31,33H,2,15-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210241 (1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...) Show SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25NOS/c1-18-12-17-26-22(18)23(25)13-15-24(16-14-23)21(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-12,17,21,25H,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210235 (4-(2-(aminomethyl)phenyl)-1-(1-phenylpentyl)piperi...) Show SMILES CCCCC(N1CCC(O)(CC1)c1ccccc1CN)c1ccccc1 |w:4.3| Show InChI InChI=1S/C23H32N2O/c1-2-3-13-22(19-9-5-4-6-10-19)25-16-14-23(26,15-17-25)21-12-8-7-11-20(21)18-24/h4-12,22,26H,2-3,13-18,24H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair

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